Page last updated: 2024-11-05

tranexamic acid and Anasarca

tranexamic acid has been researched along with Anasarca in 21 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Research Excerpts

ExcerptRelevanceReference
"Dexamethasone and tranexamic acid are used to decrease post-rhinoplasty periorbital edema and ecchymosis."9.27Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-Rhinoplasty Edema and Ecchymosis. ( Bijani, A; Ghanepur, H; Ghassemi, A; Khakzad, M; Mehdizadeh, M; Mehrbakhsh, Z; Mir, M; Moghadamnia, A; Nekoohesh, L, 2018)
"The aim of this study was to investigate the efficacy of tranexamic acid (TA) and methylprednisolone on periorbital edema, ecchymosis, and intraoperative bleeding in patients who underwent open septorhinoplasty (oSRP)."9.20The efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplasty. ( Akyiğit, A; Düzer, S; Orhan, İ; Polat, C; Sakallioğlu, Ö; Soylu, E, 2015)
"To systematically examine the role of tranexamic acid in reducing intraoperative blood loss and postoperative edema and ecchymosis among patients undergoing primary elective rhinoplasty."9.01Role of Tranexamic Acid in Reducing Intraoperative Blood Loss and Postoperative Edema and Ecchymosis in Primary Elective Rhinoplasty: A Systematic Review and Meta-analysis. ( Bezuhly, M; McGuire, C; Nurmsoo, S; Samargandi, OA, 2019)
"To investigate the results of tranexamic acid use to reduce intraoperative bleeding, postoperative eyelid edema, and periorbital ecchymosis in rhinoplasty."8.98Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty: A Systematic Review and Meta-analysis. ( de Aguiar Menezes, MV; de Souza Dantas, R; de Vasconcellos, SJA; do Nascimento-Júnior, EM; Martins-Filho, PRS; Tavares Mendes, ML, 2018)
"The aim of the present study is to examine the effect of local administration of tranexamic acid (TXA) through lateral osteotomy line on postoperative periorbital edema and ecchymosis."8.02The Effects of Intraoperative Local Tranexamic Acid on Periorbital Edema and Ecchymosis in Septorhinoplasty. ( Bezgin, SÜ; Çakabay, T; Çelebi, Ş; İpek, HD, 2021)
"Previous studies have shown that systemic tranexamic acid reduces bleeding during soft tissue surgeries and reduces postoperative ecchymosis and edema experienced by surgical patients."8.02Effect of Tranexamic Acid Administration on Postoperative Ecchymosis and Edema in Excision of Lipomas. ( Choi, YJ; Kim, WS; Lee, GY; Lee, HJ; Park, HJ, 2021)
"Dexamethasone and tranexamic acid are used to decrease post-rhinoplasty periorbital edema and ecchymosis."5.27Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-Rhinoplasty Edema and Ecchymosis. ( Bijani, A; Ghanepur, H; Ghassemi, A; Khakzad, M; Mehdizadeh, M; Mehrbakhsh, Z; Mir, M; Moghadamnia, A; Nekoohesh, L, 2018)
"The aim of this randomized double-blind study was to evaluate the efficacy of Tranexamic acid (TXA) on intraoperative bleeding, postoperative eyelid edema, and postoperative periorbital ecchymosis in rhinoplasty."5.24Efficacy of tranexamic acid on side effects of rhinoplasty: A randomized double-blind study. ( Chavoshzadeh, MA; Ghavimi, MA; Ghoreishizadeh, A; Taheri Talesh, K; Zarandi, A, 2017)
"The aim of this study was to investigate the efficacy of tranexamic acid (TA) and methylprednisolone on periorbital edema, ecchymosis, and intraoperative bleeding in patients who underwent open septorhinoplasty (oSRP)."5.20The efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplasty. ( Akyiğit, A; Düzer, S; Orhan, İ; Polat, C; Sakallioğlu, Ö; Soylu, E, 2015)
"To systematically examine the role of tranexamic acid in reducing intraoperative blood loss and postoperative edema and ecchymosis among patients undergoing primary elective rhinoplasty."5.01Role of Tranexamic Acid in Reducing Intraoperative Blood Loss and Postoperative Edema and Ecchymosis in Primary Elective Rhinoplasty: A Systematic Review and Meta-analysis. ( Bezuhly, M; McGuire, C; Nurmsoo, S; Samargandi, OA, 2019)
"To investigate the results of tranexamic acid use to reduce intraoperative bleeding, postoperative eyelid edema, and periorbital ecchymosis in rhinoplasty."4.98Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty: A Systematic Review and Meta-analysis. ( de Aguiar Menezes, MV; de Souza Dantas, R; de Vasconcellos, SJA; do Nascimento-Júnior, EM; Martins-Filho, PRS; Tavares Mendes, ML, 2018)
"The aim of the present study is to examine the effect of local administration of tranexamic acid (TXA) through lateral osteotomy line on postoperative periorbital edema and ecchymosis."4.02The Effects of Intraoperative Local Tranexamic Acid on Periorbital Edema and Ecchymosis in Septorhinoplasty. ( Bezgin, SÜ; Çakabay, T; Çelebi, Ş; İpek, HD, 2021)
"Previous studies have shown that systemic tranexamic acid reduces bleeding during soft tissue surgeries and reduces postoperative ecchymosis and edema experienced by surgical patients."4.02Effect of Tranexamic Acid Administration on Postoperative Ecchymosis and Edema in Excision of Lipomas. ( Choi, YJ; Kim, WS; Lee, GY; Lee, HJ; Park, HJ, 2021)
" We describe a case of a patient with HAE who had previously been refused surgery for tonsillitis due to the potential for oedema, in whom regular monitoring of C1-INH levels combined with intensified therapy with danazol, tranexamic acid and C1-INH concentrate enabled an uncomplicated procedure with no oedema crisis."3.78Successful management of hereditary angioedema during tonsillectomy: a case report. ( Hermans, C; Lambert, C; Vander Vorst, S, 2012)
" Patients with keratitis, stromal dystrophy and corrosion or mechanical lesion showed a secondary rise in graft thickness on the 6th postoperative day, while patients with keratoconus and those treated with tranexamic acid showed no rise on the 6th day."3.66Early postoperative changes in graft thickness after penetrating keratoplasty. Influence of host corneal disorder on time course. ( Bramsen, T; Ehlers, N, 1979)
"Edema and ecchymosis were the two most investigated outcomes."2.82Complications Associated with Rhinoplasty: An Umbrella Review of Meta-analyses. ( Chen, S; Sun, K; Wu, B; Xu, X, 2022)
"Tranexamic acid (TXA) is an antifibrinolytic, and it was used to reduce the perioperative bleeding."2.61Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial. ( Li, F; Lu, HS; Ping, WD; Sun, HF; Zhao, QM, 2019)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's14 (66.67)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Wu, B1
Chen, S1
Sun, K1
Xu, X1
İpek, HD1
Bezgin, SÜ1
Çakabay, T1
Çelebi, Ş1
Choi, YJ1
Park, HJ1
Lee, HJ1
Lee, GY1
Kim, WS1
Ghavimi, MA1
Taheri Talesh, K1
Ghoreishizadeh, A1
Chavoshzadeh, MA1
Zarandi, A1
Murad, A1
Leahy, TR1
Lenane, P1
Mehdizadeh, M1
Ghassemi, A1
Khakzad, M1
Mir, M1
Nekoohesh, L1
Moghadamnia, A1
Bijani, A1
Mehrbakhsh, Z1
Ghanepur, H1
Berkowitz, RL1
Dorweiler, MA1
Boin, MA1
Froehle, AW1
Lawless, MW1
May, JH1
de Vasconcellos, SJA1
do Nascimento-Júnior, EM1
de Aguiar Menezes, MV1
Tavares Mendes, ML1
de Souza Dantas, R1
Martins-Filho, PRS1
McGuire, C1
Nurmsoo, S1
Samargandi, OA1
Bezuhly, M1
Maniar, RN1
Pradhan, P1
Bhatnagar, N1
Maniar, A1
Bidwai, R1
Bindal, P1
Ping, WD1
Zhao, QM1
Sun, HF1
Lu, HS1
Li, F1
Sakallioğlu, Ö1
Polat, C1
Soylu, E1
Düzer, S1
Orhan, İ1
Akyiğit, A1
Chen, JY1
Chin, PL1
Moo, IH1
Pang, HN1
Tay, DK1
Chia, SL1
Lo, NN1
Yeo, SJ1
Ishida, K1
Tsumura, N1
Kitagawa, A1
Hamamura, S1
Fukuda, K1
Dogaki, Y1
Kubo, S1
Matsumoto, T1
Matsushita, T1
Chin, T1
Iguchi, T1
Kurosaka, M1
Kuroda, R1
Hermans, C1
Vander Vorst, S1
Lambert, C1
Skovgaard, C1
Holm, B1
Troelsen, A1
Lunn, TH1
Gaarn-Larsen, L1
Kehlet, H1
Husted, H1
Bramsen, T2
Ehlers, N2
Hull, DS1
Green, K1
Buyer, JG1
Nørrelykke Nissen, J1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis[NCT05774717]Phase 160 participants (Anticipated)Interventional2023-04-01Recruiting
Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery: A Double-Blind Randomized Controlled Trial[NCT04863339]Phase 20 participants (Actual)Interventional2022-03-31Withdrawn (stopped due to Challenges in recruitment)
Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgery[NCT04754230]Phase 440 participants (Actual)Interventional2021-06-17Completed
The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery[NCT04951128]Phase 450 participants (Anticipated)Interventional2021-08-01Not yet recruiting
Role of Topical Tranexamic Acid in Total Hip Arthroplasty[NCT01866943]Phase 241 participants (Actual)Interventional2011-11-30Terminated
Peri-articular Tranexamic Acid Injection in Total Knee Arthroplasty: A Randomized Controlled Trial[NCT02829346]Phase 260 participants (Actual)Interventional2012-10-31Completed
Efficacy of Low-dose Intra-articular Tranexamic Acid in Total Knee Replacement; A Prospective Triple-blinded Randomized Controlled Trial.[NCT01850394]152 participants (Actual)Interventional2010-01-31Completed
Evaluation of the Pharmacokinetic Profile of Tranexamic Acid, After Injection in a Knee Neo-articulation.[NCT02319915]Early Phase 114 participants (Actual)Interventional2015-02-18Completed
Tranexamic Acid in Knee Joint Surgery - a Randomised Controlled Trial[NCT02278263]Phase 4150 participants (Actual)Interventional2014-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Bleeding VAS - POD1

Patient-reported Visual Analog Scale - Bleeding Score Day 1. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 1 (assessed within first 24 hours following surgery)

Interventionscore on a scale (Mean)
Normal Saline5.03
1,000mg IV Tranexamic Acid4.82

Bleeding VAS - POD2

Patient-reported Visual Analog Scale - Bleeding Score Day 2. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 2

Interventionscore on a scale (Mean)
Normal Saline4.47
1,000mg IV Tranexamic Acid3.89

Bleeding VAS - POD3

Patient-reported Visual Analog Scale - Bleeding Score Day 3. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 3

Interventionscore on a scale (Mean)
Normal Saline2.93
1,000mg IV Tranexamic Acid2.29

Bleeding VAS - POD4

Patient-reported Visual Analog Scale - Bleeding Score Day 4. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 4

Interventionscore on a scale (Mean)
Normal Saline2.12
1,000mg IV Tranexamic Acid1.44

Bleeding VAS - POD5

Patient-reported Visual Analog Scale - Bleeding Score Day 5. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 5

Interventionscore on a scale (Mean)
Normal Saline1.32
1,000mg IV Tranexamic Acid1.15

Bleeding VAS - POD6

Patient-reported Visual Analog Scale - Bleeding Score Day 6. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 6

Interventionscore on a scale (Mean)
Normal Saline1.36
1,000mg IV Tranexamic Acid0.76

Bleeding VAS - POD7

Patient-reported Visual Analog Scale - Bleeding Score Day 7. Score range: 0 (no bleeding) to 10 (uncontrolled bleeding). (NCT04754230)
Timeframe: Postoperative Day 7

Interventionscore on a scale (Mean)
Normal Saline0.97
1,000mg IV Tranexamic Acid0.72

Frequency of Participant Follow-up

Number of patients in each arm requiring evaluation by the resident service for bleeding concerns expressed by the recovery nurse (in PACU), had any follow-up visit or phone call outside of regularly scheduled follow-up (NCT04754230)
Timeframe: Day of surgery through 1 week

,
InterventionParticipants (Count of Participants)
PACUFollow-up visitFollow-up phone call
1,000mg IV Tranexamic Acid012
Normal Saline002

Guaze Saturation VAS Though POD7

Patient-reported Visual Analog Scale - Guaze Saturation Score through Postoperative Day 7. Score range: 0 (not at all) to 10 (dripping blood). (NCT04754230)
Timeframe: Postoperative Day 2 through Postoperative Day 7

,
Interventionscore on a scale (Mean)
Postoperative day 2Postoperative day 3Postoperative day 4Postoperative day 5Postoperative day 6Postoperative day 7
1,000mg IV Tranexamic Acid4.562.090.760.400.290.28
Normal Saline5.163.031.741.110.990.80

Estimated Blood Loss

Estimated Blood Loss defined as Pre Op Hgb mins the Post Op Day two Hgb. (NCT01866943)
Timeframe: Pre Op, Post Op Day 2

InterventionHemoglobin (grams/deciliter) (Mean)
Baseline Population2.93

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: 2 week

Interventionunits on a scale (Mean)
All Study Participants65.76

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: 6 week

Interventionunits on a scale (Mean)
All Study Participants81.77

Harris Hip Scores

Standardized questionnaire that measures clinical function related to the hip. Total potential range is from 4.0 - 96.0. A higher score indicates a more favorable clinical outcome. (NCT01866943)
Timeframe: Preoperative

Interventionunits on a scale (Mean)
All Study Participants58.34

Mid Thigh Circumference

Measurement of the thigh at the half way point between the prominence of the greater trochanter and the lateral epicondyle of the femur. No data recorded at 2 weeks or 6 weeks for this study population. (NCT01866943)
Timeframe: Pre Op

Interventioncentimeters (Mean)
Baseline Population52.99

Number of Patients Required Blood Transfusion

(NCT01850394)
Timeframe: postoperative period (5 days after surgery)

Interventionparticipants (Number)
Control Group10
TXA-250 Group6
TXA-500 Group0

Total Hemoglobin Loss

Total hemoglobin loos measured by difference between hemoglobin preoperatively and the fourth postoperative day (NCT01850394)
Timeframe: 5 days after surgery

Interventiong/dL (Mean)
Control Group2.9
TXA-250 Group2.2
TXA-500 Group2.2

Knee Function Scores

"Knee function score was measured with 2 methods, and were evaluated preoperatively and then postoperatively at 3-month, 6-month, and 1-year period.~Knee Society Knee Score using for rating knee function measurement and subdivided into two parts; knee score and function score 1.1. Knee score : calculated from pain, presence of deformity, total range of flexion, alignment, and stability. Total score is 100 (0-100), more score means better.~1.2. Function score : calculated from patient's ability to walk and climb stairs. The score ranges from 0-100, more score means better.~Western Ontario and McMaster Universities Arthritis Index or WOMAC score : a widely used, standardized questionnaires for evaluating the condition of patients with knee osteoarthritis, including pain (score = 0-20), stiffness (0-8), and functional limitation (0-68). Total score ranges from 0-68, lower score means better." (NCT01850394)
Timeframe: 1 year after surgery

,,
Interventionunits on a scale (Mean)
Knee Society Knee score at 1 yearWOMAC score at 1 year
Control Group148.915.5
TXA-250 Group151.215.1
TXA-500 Group150.914.5

Number of Patients Having Postoperative Complications

"Postoperative complications were measured as an incidence of the following complications;~wound hematoma~surgical site infection~systemic infection~deep vein thrombosis~pulmonary embolism~knee stiffness requiring manipulation~medical complication such as myocardial infarction, congestive hear failure" (NCT01850394)
Timeframe: postoperative 1-year period

,,
Interventionparticipants (Number)
Re-clamp incidenceRe-dressing incidenceVenous thromboembolic complicationCongestive heart failure
Control Group6340
TXA-250 Group1011
TXA-500 Group0020

Perioperative Blood Loss

"Drainage blood loss measured by accumulating total drainage volume postoperatively~Calculated total blood loss measured by using specific formula and difference between hematocrit preoperatively and the fourth postoperative day" (NCT01850394)
Timeframe: 5 days after surgery

,,
Interventionml (Median)
Drainage blood lossCalculated total blood loss
Control Group546.9329.2
TXA-250 Group475.0239.7
TXA-500 Group430.2217.2

Blood Loss

"The loss of haemoglobin (Hb) was then estimated according to the formula:~Hb(loss) = Blood volume (BV) x (Hbi-Hbe) x 0.001+Hbt~where Hb (loss) (g) is the amount of Hb lost, Hbi (g/L) the Hb concentration before surgery, Hbe (g/L) is the Hbe concentration on the third day after surgery, and Hbt (g) is the total amount of allogeneic Hb transfused. A unit of banked blood is considered to contain a minimum of 40g Hb (Blood component data sheet, New Zealand Blood Services [NZBS]). All units of blood are processed and stored in a nationally standardised manner. The blood loss (ml) was related to the patient's preoperative Hb value (g/L):~Blood loss =1000 x Hb(loss) /Hbi" (NCT02278263)
Timeframe: Post operative day 3

Interventionmls (Mean)
Control1090
Intraarticular716
Systemic746

Length of Stay (LOS)

Day of surgery is counted as Day 0. (NCT02278263)
Timeframe: Average length of stay is expected to be 3 to 5 days

Interventiondays (Median)
Control4
Topical4
Systemic4

Number of Participants Receiving Allogenic Blood Transfusion

"Those patients receiving blood products. Standardised protocol is as follows:~The criterion for transfusion of blood products will be a haemoglobin < 80g/L or a haemoglobin <100g/L in a patient with ischaemic heart disease or with significant symptomatology" (NCT02278263)
Timeframe: Participants will be followed for the duration of their hospital stay expected to be an average of 3-5 days

InterventionParticipants (Count of Participants)
Control2
Topical1
Systemic0

Perioperative Fluid Administration

Intravenous fluid (excluding blood transfusion) given during and first 24 hours after surgery (NCT02278263)
Timeframe: Day 1

Interventionmls (Mean)
Control1765
Topical1613
Systemic1807

Number of Participants Experiencing Symptomatic Venothromboembolic (VTE) Disease

Rates of deep vein thrombosis (DVT) and pulmonary embolus (PE) in each group recorded as a percentage (NCT02278263)
Timeframe: Postoperatively within 30 days after surgery

,,
InterventionParticipants (Count of Participants)
DVTPE
Control00
Systemic01
Topical02

Range of Active Flexion

Range of motion measured in degrees on postoperative days 1-3 (NCT02278263)
Timeframe: Days 1-3

,,
Interventiondegrees (Mean)
Day 1Day 2Day 3
Control577175
Systemic587278
Topical657582

Range of Passive Flexion

Range of motion measured in degrees for postoperative days 1 to 3 (NCT02278263)
Timeframe: Days 1-3

,,
Interventiondegrees (Mean)
Day 1Day 2Day 3
Control657682
Systemic688087
Topical748187

Reviews

4 reviews available for tranexamic acid and Anasarca

ArticleYear
Complications Associated with Rhinoplasty: An Umbrella Review of Meta-analyses.
    Aesthetic plastic surgery, 2022, Volume: 46, Issue:2

    Topics: Ecchymosis; Edema; Humans; Osteotomy; Rhinoplasty; Tranexamic Acid; Treatment Outcome

2022
Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty: A Systematic Review and Meta-analysis.
    JAMA otolaryngology-- head & neck surgery, 2018, 09-01, Volume: 144, Issue:9

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration Schedule; Ecchymosis; Edema; Eyel

2018
Role of Tranexamic Acid in Reducing Intraoperative Blood Loss and Postoperative Edema and Ecchymosis in Primary Elective Rhinoplasty: A Systematic Review and Meta-analysis.
    JAMA facial plastic surgery, 2019, May-01, Volume: 21, Issue:3

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Humans; Postoperative Complication

2019
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
    Medicine, 2019, Volume: 98, Issue:16

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur

2019
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
    Medicine, 2019, Volume: 98, Issue:16

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur

2019
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
    Medicine, 2019, Volume: 98, Issue:16

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur

2019
Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial.
    Medicine, 2019, Volume: 98, Issue:16

    Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Ecchymosis; Edema; Eyelid Diseases; Humans; Nasal Sur

2019

Trials

8 trials available for tranexamic acid and Anasarca

ArticleYear
Efficacy of tranexamic acid on side effects of rhinoplasty: A randomized double-blind study.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2017, Volume: 45, Issue:6

    Topics: Adult; Antifibrinolytic Agents; Blood Loss, Surgical; Double-Blind Method; Ecchymosis; Edema; Female

2017
Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-Rhinoplasty Edema and Ecchymosis.
    Aesthetic plastic surgery, 2018, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Dexamethasone; Double-Blind Method; Drug Therapy, Combinati

2018
Role of Suction Drain after Knee Arthroplasty in the Tranexamic Acid Era: A Randomized Controlled Study.
    Clinics in orthopedic surgery, 2019, Volume: 11, Issue:1

    Topics: Aged; Analgesics, Opioid; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Edema; Female; H

2019
The efficacy of tranexamic acid and corticosteroid on edema and ecchymosis in septorhinoplasty.
    Annals of plastic surgery, 2015, Volume: 74, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Antifibrinolytic Agents; Blood Loss, Surgical; Drug Administration

2015
Intravenous versus intra-articular tranexamic acid in total knee arthroplasty: A double-blinded randomised controlled noninferiority trial.
    The Knee, 2016, Volume: 23, Issue:1

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replace

2016
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty.
    International orthopaedics, 2011, Volume: 35, Issue:11

    Topics: Aged; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Edema; Female;

2011
No effect of fibrin sealant on drain output or functional recovery following simultaneous bilateral total knee arthroplasty: a randomized, double-blind, placebo-controlled study.
    Acta orthopaedica, 2013, Volume: 84, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Double-Bli

2013
No additive effect of tranexamic acid and naproxen on corneal deswelling. A study on oedema after uncomplicated intracapsular cataract extraction with anterior chamber lens implantation.
    Acta ophthalmologica, 1986, Volume: 64, Issue:3

    Topics: Aged; Cataract Extraction; Clinical Trials as Topic; Cornea; Corneal Diseases; Cyclohexanecarboxylic

1986

Other Studies

9 other studies available for tranexamic acid and Anasarca

ArticleYear
The Effects of Intraoperative Local Tranexamic Acid on Periorbital Edema and Ecchymosis in Septorhinoplasty.
    The Journal of craniofacial surgery, 2021, Sep-01, Volume: 32, Issue:6

    Topics: Ecchymosis; Edema; Humans; Postoperative Complications; Rhinoplasty; Tranexamic Acid

2021
Effect of Tranexamic Acid Administration on Postoperative Ecchymosis and Edema in Excision of Lipomas.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2021, 03-01, Volume: 47, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Dermatologic Surgical

2021
Acute Genital Swelling Heralding C1 Esterase Inhibitor Deficiency in a Child.
    Pediatric dermatology, 2017, Volume: 34, Issue:5

    Topics: Angioedemas, Hereditary; Child, Preschool; Complement C1 Inhibitor Protein; Diagnosis, Differential;

2017
Commentary on: "Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-rhinoplasty and Edema and Ecchymosis".
    Aesthetic plastic surgery, 2018, Volume: 42, Issue:1

    Topics: Dexamethasone; Ecchymosis; Edema; Humans; Osteotomy; Postoperative Complications; Rhinoplasty; Trane

2018
Improved Early Postoperative Range of Motion in Total Knee Arthroplasty Using Tranexamic Acid: A Retrospective Analysis.
    The journal of knee surgery, 2019, Volume: 32, Issue:2

    Topics: Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Case-Control Studies

2019
Successful management of hereditary angioedema during tonsillectomy: a case report.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2012, Volume: 23, Issue:2

    Topics: Adult; Angioedemas, Hereditary; Complement C1 Inhibitor Protein; Danazol; Edema; Female; Humans; Ton

2012
The influence of antifibrinolytica on traumatic hyphaema and corneal oedema.
    Acta ophthalmologica. Supplementum, 1980, Issue:145

    Topics: Adult; Aged; Antifibrinolytic Agents; Cornea; Corneal Diseases; Corneal Transplantation; Cyclohexane

1980
Early postoperative changes in graft thickness after penetrating keratoplasty. Influence of host corneal disorder on time course.
    Acta ophthalmologica, 1979, Volume: 57, Issue:2

    Topics: Age Factors; Cornea; Corneal Diseases; Corneal Dystrophies, Hereditary; Corneal Transplantation; Cor

1979
Tranexamic acid and corneal deturgescence.
    Acta ophthalmologica, 1979, Volume: 57, Issue:2

    Topics: Animals; Cornea; Cyclohexanecarboxylic Acids; Edema; Female; In Vitro Techniques; Injections, Intrav

1979