tranexamic acid has been researched along with Alzheimer Disease in 1 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Second, treatment of AD mice with the plasmin inhibitor tranexamic acid aggravated pathology, whereas removal of fibrinogen from the circulation of AD mice with ancrod treatment attenuated measures of neuroinflammation and vascular pathology." | 7.74 | Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease. ( Melchor, JP; Paul, J; Strickland, S, 2007) |
| " Second, treatment of AD mice with the plasmin inhibitor tranexamic acid aggravated pathology, whereas removal of fibrinogen from the circulation of AD mice with ancrod treatment attenuated measures of neuroinflammation and vascular pathology." | 3.74 | Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease. ( Melchor, JP; Paul, J; Strickland, S, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paul, J | 1 |
| Strickland, S | 1 |
| Melchor, JP | 1 |
1 other study available for tranexamic acid and Alzheimer Disease
| Article | Year |
|---|---|
Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Disease Models, Animal; Disease Progression; Fibrin | 2007 |