Page last updated: 2024-11-05

tranexamic acid and Acute Lung Injury

tranexamic acid has been researched along with Acute Lung Injury in 5 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).

Research Excerpts

ExcerptRelevanceReference
"It has been demonstrated that tranexamic acid (TXA), a synthetic derivative of lysine, alleviates lung damage in a trauma-hemorrhagic shock (T/HS) model."7.88Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats. ( Feng, C; Gao, Y; Jin, H; Li, T; Liu, Y; Teng, Y, 2018)
"Sprague-Dawley rats were subjected to polytrauma (laparotomy, and trauma to intestines, liver, right leg skeletal muscle, and right femur fracture), then bled 40% of their blood volume."5.46Tranexamic Acid Attenuates The Loss of Lung Barrier Function in a Rat Model of Polytrauma And Hemorrhage With Resuscitation. ( Cap, AP; Darlington, DN; Dubick, MA; Schwacha, MG; Wu, X, 2017)
"It has been demonstrated that tranexamic acid (TXA), a synthetic derivative of lysine, alleviates lung damage in a trauma-hemorrhagic shock (T/HS) model."3.88Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats. ( Feng, C; Gao, Y; Jin, H; Li, T; Liu, Y; Teng, Y, 2018)
"Sprague-Dawley rats were subjected to polytrauma (laparotomy, and trauma to intestines, liver, right leg skeletal muscle, and right femur fracture), then bled 40% of their blood volume."1.46Tranexamic Acid Attenuates The Loss of Lung Barrier Function in a Rat Model of Polytrauma And Hemorrhage With Resuscitation. ( Cap, AP; Darlington, DN; Dubick, MA; Schwacha, MG; Wu, X, 2017)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cybulska, P1
Goss, C1
Tew, WP1
Parameswaran, R1
Sonoda, Y1
Teng, Y1
Feng, C1
Liu, Y1
Jin, H1
Gao, Y1
Li, T1
Engelbrecht, S1
Wood, EM1
Cole-Sinclair, MF1
Bock, A1
Tucker, N1
Kelher, MR1
Khan, SY1
Gonzalez, E1
Wohlauer, M1
Hansen, K1
Dzieciatkowska, M1
Sauaia, A1
Banerjee, A1
Moore, EE1
Silliman, CC1
Wu, X1
Dubick, MA1
Schwacha, MG1
Cap, AP1
Darlington, DN1

Reviews

1 review available for tranexamic acid and Acute Lung Injury

ArticleYear
Indications for and complications of transfusion and the management of gynecologic malignancies.
    Gynecologic oncology, 2017, Volume: 146, Issue:2

    Topics: Acute Lung Injury; Anemia; Antifibrinolytic Agents; Blood Loss, Surgical; Erythrocyte Transfusion; F

2017

Other Studies

4 other studies available for tranexamic acid and Acute Lung Injury

ArticleYear
Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats.
    Experimental animals, 2018, Jul-30, Volume: 67, Issue:3

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Disease Models,

2018
Clinical transfusion practice update: haemovigilance, complications, patient blood management and national standards.
    The Medical journal of Australia, 2013, Sep-16, Volume: 199, Issue:6

    Topics: Acute Lung Injury; Anticoagulants; Antifibrinolytic Agents; Australia; Blood Transfusion; Clinical P

2013
α-Enolase Causes Proinflammatory Activation of Pulmonary Microvascular Endothelial Cells and Primes Neutrophils Through Plasmin Activation of Protease-Activated Receptor 2.
    Shock (Augusta, Ga.), 2015, Volume: 44, Issue:2

    Topics: Acute Lung Injury; Cell Membrane; Endothelial Cells; Flow Cytometry; Humans; Inflammation; Intercell

2015
Tranexamic Acid Attenuates The Loss of Lung Barrier Function in a Rat Model of Polytrauma And Hemorrhage With Resuscitation.
    Shock (Augusta, Ga.), 2017, Volume: 47, Issue:4

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Hemorrhage; Lung; Male; Multiple Trauma; Rats; R

2017