tranexamic acid has been researched along with Acidosis in 6 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our purposes were to study the efficacy of tranexamic acid (TXA) and prothrombin complex concentrate (PCC) on a traumatic coagulopathy with a severe native metabolic acidosis and compare the efficacy of PCC versus fresh frozen plasma (FFP) to reverse a dilutional coagulopathy." | 7.79 | The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis. ( Eckert, M; Izenberg, S; Martin, MJ; McVay, D; Nelson, D; Porta, CR; Salgar, S, 2013) |
| " Our purposes were to study the efficacy of tranexamic acid (TXA) and prothrombin complex concentrate (PCC) on a traumatic coagulopathy with a severe native metabolic acidosis and compare the efficacy of PCC versus fresh frozen plasma (FFP) to reverse a dilutional coagulopathy." | 3.79 | The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis. ( Eckert, M; Izenberg, S; Martin, MJ; McVay, D; Nelson, D; Porta, CR; Salgar, S, 2013) |
| "Future treatment of trauma-induced coagulopathy may be based on systemic antifibrinolytics, local haemostatics and individualized point-of-care-guided rational use of coagulation factor concentrates such as fibrinogen, prothrombin complex concentrate, recombinant factor VIIa and factor XIII." | 2.48 | Emerging treatment strategies for trauma-induced coagulopathy. ( Fries, D; Sorensen, B, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Porta, CR | 1 |
| Nelson, D | 1 |
| McVay, D | 1 |
| Salgar, S | 1 |
| Eckert, M | 1 |
| Izenberg, S | 1 |
| Martin, MJ | 1 |
| Panteli, M | 1 |
| Pountos, I | 1 |
| Giannoudis, PV | 1 |
| Jansen, JO | 1 |
| Thomas, R | 1 |
| Loudon, MA | 1 |
| Brooks, A | 1 |
| Annecke, T | 1 |
| Geisenberger, T | 1 |
| Kürzl, R | 1 |
| Penning, R | 1 |
| Heindl, B | 1 |
| Sorensen, B | 1 |
| Fries, D | 1 |
| Dirkmann, D | 1 |
| Radü-Berlemann, J | 1 |
| Görlinger, K | 1 |
| Peters, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Estimation of Coagulation Factor XIII Activity Based on the Initial Plasma Fibrinogen Level in Trauma[NCT03634215] | 357 participants (Actual) | Observational | 2018-09-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for tranexamic acid and Acidosis
| Article | Year |
|---|---|
Pharmacological adjuncts to stop bleeding: options and effectiveness.
Topics: Acidosis; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Trans | 2016 |
Damage control resuscitation for patients with major trauma.
Topics: Acidosis; Blood Cells; Blood Coagulation Disorders; Calcium; Factor VIIa; Fibrinogen; Hemostasis; Hu | 2009 |
Emerging treatment strategies for trauma-induced coagulopathy.
Topics: Acidosis; Anemia; Antifibrinolytic Agents; Bandages; Blood Coagulation Disorders; Blood Coagulation | 2012 |
3 other studies available for tranexamic acid and Acidosis
| Article | Year |
|---|---|
The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis.
Topics: Acidosis; Animals; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Factors; | 2013 |
Algorithm-based coagulation management of catastrophic amniotic fluid embolism.
Topics: Acidosis; Adult; Algorithms; Blood Coagulation Factors; Blood Component Transfusion; Cardiovascular | 2010 |
Recombinant tissue-type plasminogen activator-evoked hyperfibrinolysis is enhanced by acidosis and inhibited by hypothermia but still can be blocked by tranexamic acid.
Topics: Acidosis; Adult; Blood Coagulation; Blood Coagulation Disorders; Female; Fibrinolytic Agents; Humans | 2013 |