Page last updated: 2024-11-05

tranexamic acid and ACL Injuries

tranexamic acid has been researched along with ACL Injuries in 6 studies

Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.

Research Excerpts

ExcerptRelevanceReference
"Administration of intravenous tranexamic acid significantly improved swelling, pain and lower ROM restriction in patients undergoing ACL reconstruction."9.69The effect of tranexamic acid injection during anterior cruciate ligament reconstruction surgery on postoperative bleeding, pain and swelling. ( Akbari-Aghdam, H; Entezari, R; Mousavi, H, 2023)
"The purpose of this double-blind, randomized, controlled trial was to evaluate the use of intravenous (IV) tranexamic acid (TXA) in patients undergoing primary bone-patellar tendon-bone (BPTB) anterior cruciate ligament reconstruction (ACLR) regarding postoperative hemarthrosis, pain, opioid consumption, and quadriceps atrophy and activation."9.41Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial. ( Alaia, MJ; Baron, SL; Bloom, DA; Campbell, KA; Fried, JW; Hurley, ET; Jazrawi, LM; Popovic, J; Strauss, EJ, 2021)
"Administration of intravenous tranexamic acid significantly improved swelling, pain and lower ROM restriction in patients undergoing ACL reconstruction."5.69The effect of tranexamic acid injection during anterior cruciate ligament reconstruction surgery on postoperative bleeding, pain and swelling. ( Akbari-Aghdam, H; Entezari, R; Mousavi, H, 2023)
"The purpose of this double-blind, randomized, controlled trial was to evaluate the use of intravenous (IV) tranexamic acid (TXA) in patients undergoing primary bone-patellar tendon-bone (BPTB) anterior cruciate ligament reconstruction (ACLR) regarding postoperative hemarthrosis, pain, opioid consumption, and quadriceps atrophy and activation."5.41Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial. ( Alaia, MJ; Baron, SL; Bloom, DA; Campbell, KA; Fried, JW; Hurley, ET; Jazrawi, LM; Popovic, J; Strauss, EJ, 2021)
"To analyze the available literature on hemarthrosis, pain, functional outcomes, and complications after administration of tranexamic acid in ACL reconstruction procedures."5.12Tranexamic Acid in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis. ( Ciccotti, MG; Gonzalez, TA; Hammoud, S; Johns, WL; Patel, NK; Walley, KC, 2021)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's5 (83.33)2.80

Authors

AuthorsStudies
Mousavi, H1
Akbari-Aghdam, H1
Entezari, R1
Ma, R1
Wu, M1
Li, Y1
Wang, J1
Wang, W1
Yang, P1
Wang, K1
Fried, JW1
Bloom, DA1
Hurley, ET1
Baron, SL1
Popovic, J1
Campbell, KA1
Strauss, EJ1
Jazrawi, LM1
Alaia, MJ1
Johns, WL1
Walley, KC1
Hammoud, S1
Gonzalez, TA1
Ciccotti, MG1
Patel, NK1
Kalina, R1
Fidler, E1
Béreš, M1
Zeman, P1
Sigmund, M1
Gallo, J1
Felli, L1
Revello, S1
Burastero, G1
Gatto, P1
Carletti, A1
Formica, M1
Alessio-Mazzola, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Administration of Tranexamic Acid Significantly Improved Clarity of Visual Field in Arthroscopic Shoulder Surgery. A Prospective, Double-blind and Randomized Controlled Trial[NCT04025736]72 participants (Actual)Interventional2017-06-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for tranexamic acid and ACL Injuries

ArticleYear
Tranexamic Acid in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis.
    The American journal of sports medicine, 2021, Volume: 49, Issue:14

    Topics: Adult; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Hemarthrosis;

2021

Trials

5 trials available for tranexamic acid and ACL Injuries

ArticleYear
The effect of tranexamic acid injection during anterior cruciate ligament reconstruction surgery on postoperative bleeding, pain and swelling.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023, Volume: 33, Issue:3

    Topics: Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Humans; Knee Joint;

2023
The comparative efficacies of intravenous administration and intra-articular injection of tranexamic acid during anterior cruciate ligament reconstruction for reducing postoperative hemarthrosis: a prospective randomized study.
    BMC musculoskeletal disorders, 2021, Jan-26, Volume: 22, Issue:1

    Topics: Administration, Intravenous; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconst

2021
Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2021, Volume: 37, Issue:6

    Topics: Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Autografts; Bone-Pat

2021
[Effect of a Single Dose of Tranexamic Acid Administered during Anterior Cruciate Ligament Reconstruction Using Hamstrings: a Randomized Clinical Study].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2021, Volume: 88, Issue:3

    Topics: Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Humans; Knee Joint;

2021
Single Intravenous Administration of Tranexamic Acid in Anterior Cruciate Ligament Reconstruction to Reduce Postoperative Hemarthrosis and Increase Functional Outcomes in the Early Phase of Postoperative Rehabilitation: A Randomized Controlled Trial.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2019, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; A

2019