trandolapril has been researched along with Pain* in 1 studies
1 other study(ies) available for trandolapril and Pain
Article | Year |
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The prevention of pain from sickle cell disease by trandolapril.
A 48-year-old African-American woman with both sickle cell anemia and chronic pain was treated with a hydrophobic angiotensin I-converting enzyme (ACE) inhibitor. This resulted in the complete resolution of her pain. When the ACE inhibitor was deliberately stopped, her pain recurred, only to cease again after the ACE inhibitor was deliberately resumed. The activation of ACE may be an early step in the arterial vaso-occlusion typical of sickle cell disease. Topics: Anemia, Sickle Cell; Angiotensin-Converting Enzyme Inhibitors; Black or African American; Cell Hypoxia; Chronic Disease; Female; Gene Frequency; Genotype; Humans; Indoles; Middle Aged; Pain; Peptidyl-Dipeptidase A; Vasoconstriction | 2007 |