tramiprosate has been researched along with Muscle Contraction in 19 studies
tramiprosate: GABA receptor agonist and a glycosaminoglycan mimetic; has nootropic acitivity; structure; a sulfonate analog of GABA
3-aminopropanesulfonic acid : An amino sulfonic acid that is the 3-amino derivative of propanesulfonic acid.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5." | 1.28 | GABAA receptor-mediated stimulation of non-adrenergic non-cholinergic neurones in the dog ileocolonic junction. ( Boeckxstaens, GE; Herman, AG; Pelckmans, PA; Rampart, M; Ruytjens, IF; Van Maercke, YM; Verbeuren, TJ, 1990) |
| " There was a sinistral shift of the GABA dose-response curve in the presence of 10 pM cortisol, with a significant potentiation of the GABA-induced contractions over the lower dose range of GABA (3-30 microM), whereas 100 nM cortisol caused a non-parallel dextral shift of the GABA dose-response curve, with a depression of the maximum GABA response indicative of non-competitive antagonism." | 1.27 | Cortisol: a potent biphasic modulator at GABAA-receptor complexes in the guinea pig isolated ileum. ( Johnston, GA; Kerr, DI; Ong, J, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (78.95) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Santicioli, P | 4 |
| Maggi, CA | 5 |
| Meli, A | 5 |
| Giotti, A | 3 |
| Luzzi, S | 2 |
| Spagnesi, S | 2 |
| Zilletti, L | 3 |
| Franconi, F | 1 |
| Manzini, S | 2 |
| Martini, F | 1 |
| Stendardi, I | 1 |
| Krantis, A | 2 |
| Mattar, K | 1 |
| Glasgow, I | 1 |
| Ozdem, SS | 1 |
| Sadan, G | 1 |
| Usta, C | 1 |
| Taşatargil, A | 1 |
| Frye, GD | 1 |
| Fincher, AS | 1 |
| Lorenzetti, M | 1 |
| Trzeciakowski, J | 1 |
| Griffith, WH | 1 |
| Boeckxstaens, GE | 1 |
| Pelckmans, PA | 1 |
| Rampart, M | 1 |
| Ruytjens, IF | 1 |
| Verbeuren, TJ | 1 |
| Herman, AG | 1 |
| Van Maercke, YM | 1 |
| Tonini, M | 2 |
| Onori, L | 1 |
| Rizzi, CA | 2 |
| Perucca, E | 1 |
| Manzo, L | 2 |
| Crema, A | 1 |
| Barbier, AJ | 1 |
| Guenaneche, F | 1 |
| Lefebvre, RA | 1 |
| Costa, LG | 1 |
| Candura, SM | 1 |
| Olibet, G | 1 |
| Garlaschelli, L | 1 |
| Harding, RK | 1 |
| Ong, J | 2 |
| Kerr, DI | 1 |
| Johnston, GA | 1 |
| Kannisto, P | 1 |
| Owman, C | 1 |
| Schmidt, G | 1 |
| Walles, B | 1 |
19 other studies available for tramiprosate and Muscle Contraction
| Article | Year |
|---|---|
GABAB receptor mediated inhibition of field stimulation-induced contractions of rabbit bladder muscle in-vitro.
Topics: Acetylcholine; Amino Acids; Amino Acids, Neutral; Animals; Atropine; Baclofen; Electric Stimulation; | 1984 |
GABAA and GABAB receptor-mediated effects in guinea-pig ileum.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Ma | 1983 |
GABAB receptor mediated inhibition of field stimulation induced contractions of detrusor muscle strips from newborn rats.
Topics: Aging; Animals; Animals, Newborn; Atropine; Baclofen; Electric Stimulation; Female; Hexamethonium Co | 1984 |
Homotaurine: a GABAB antagonist in guinea-pig ileum.
Topics: Animals; Baclofen; Electric Stimulation; GABA Antagonists; Guinea Pigs; Ileum; In Vitro Techniques; | 1983 |
The effect of taurine on high potassium-and noradrenaline-induced contraction in rabbit ear artery.
Topics: Alanine; Animals; Arteries; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle | 1982 |
Rat gastroduodenal motility in vivo: interaction of GABA and VIP in control of spontaneous relaxations.
Topics: Animals; Bicuculline; Duodenum; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; | 1998 |
Effect of experimental diabetes on GABA-mediated inhibition of neurally induced contractions in rat isolated trachea.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Blood Glucose; Body Weight; Diabetes Mellitus, Experi | 2000 |
Comparison of contractile responses of the guinea pig ileum longitudinal muscle to ethanol and GABAA agonists.
Topics: Animals; Atropine; Bicuculline; Chlorides; Ethanol; Female; Guinea Pigs; Ileum; In Vitro Techniques; | 1990 |
GABAA receptor-mediated stimulation of non-adrenergic non-cholinergic neurones in the dog ileocolonic junction.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Colon; Dogs; Electric Stimulation; Female; GABA Antag | 1990 |
Involvement of substance P in the excitatory action of GABAA agonists on cholinergic neurons in the guinea-pig ileum.
Topics: Animals; Capsaicin; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol | 1987 |
Influence of GABA and ethylenediamine in the guinea-pig duodenum.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Duodenum; Electric Stimulation; Ethylenediamines; Fe | 1989 |
Interaction of the pyrethroid insecticides tetramethrin and cypermethrin with enteric cholinergic transmission in the guinea-pig.
Topics: Animals; Cholinergic Fibers; Electric Stimulation; Female; Guinea Pigs; Ileum; Insecticides; Male; M | 1989 |
GABA-related actions in isolated in vitro preparations of the rat small intestine.
Topics: Animals; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Intestine, Small; Male; Muscle Contra | 1987 |
Cortisol: a potent biphasic modulator at GABAA-receptor complexes in the guinea pig isolated ileum.
Topics: Animals; Baclofen; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hydrocortisone; Ileum; In Vitro Tec | 1987 |
GABAA and GABAB receptors in detrusor strips from guinea-pig bladder dome.
Topics: Animals; Baclofen; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; | 1985 |
Dual effect of GABA on the contractile activity of the guinea-pig isolated urinary bladder.
Topics: Acetylcholine; Animals; Baclofen; Dimethylphenylpiperazinium Iodide; Drug Interactions; gamma-Aminob | 1985 |
Evidence for prejunctional GABAB receptors mediating inhibition of ovarian follicle contraction induced by nerve stimulation.
Topics: Animals; Atropine; Baclofen; Bicuculline; Cattle; Electric Stimulation; Female; gamma-Aminobutyric A | 1986 |
GABA A receptor mediated neurogenic inhibition of motility in the small intestine of urethane-anaesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; Gastrointestinal Motility; Hexamethonium Compounds; In Vitro Techn | 1986 |
Uptake inhibitors potentiate gamma-aminobutyric acid-induced contractile responses in the isolated ileum of the guinea-pig.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male | 1987 |