tramiprosate has been researched along with Disease Models, Animal in 11 studies
tramiprosate: GABA receptor agonist and a glycosaminoglycan mimetic; has nootropic acitivity; structure; a sulfonate analog of GABA
3-aminopropanesulfonic acid : An amino sulfonic acid that is the 3-amino derivative of propanesulfonic acid.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of this study was to evaluate the neuroprotective potential of RGC death induced by the in vivo transient increase in intraocular pressure (IOP) of a combined treatment with forskolin, homotaurine, and L-carnosine." | 3.81 | Intravitreal injection of forskolin, homotaurine, and L-carnosine affords neuroprotection to retinal ganglion cells following retinal ischemic injury. ( Adornetto, A; Bagetta, G; Cavaliere, F; Corasaniti, MT; Morrone, LA; Nucci, C; Rusciano, D; Russo, R; Varano, GP, 2015) |
| "With the surge in the cases of Alzheimer's disease (AD) over the years, several targets have been explored to curb the disease." | 1.56 | Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives. ( Chakravarty, H; Chen, WH; Ju, Y; Tam, KY, 2020) |
| " An anti-amyloidogenic bis-styrylbenzene derivative, KMS80013, showed excellent oral bioavailability (F=46." | 1.39 | Therapeutic and pharmacokinetic characterizations of an anti-amyloidogenic bis-styrylbenzene derivative for Alzheimer's disease treatment. ( Ahn, YG; Byeon, SR; Jeon, M; Kim, DJ; Kim, HV; Kim, HY; Kim, MS; Kim, YS; Kong, JY, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 4 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Byeon, SR | 1 |
| Kim, HV | 1 |
| Jeon, M | 1 |
| Ahn, YG | 1 |
| Kim, MS | 1 |
| Kong, JY | 1 |
| Kim, HY | 1 |
| Kim, YS | 1 |
| Kim, DJ | 1 |
| Singla, R | 1 |
| Mishra, A | 1 |
| Joshi, R | 1 |
| Sarma, P | 1 |
| Kumar, R | 1 |
| Kaur, G | 1 |
| Sharma, AR | 1 |
| Jain, A | 1 |
| Prakash, A | 1 |
| Bhatia, A | 1 |
| Medhi, B | 1 |
| Chakravarty, H | 1 |
| Ju, Y | 1 |
| Chen, WH | 1 |
| Tam, KY | 1 |
| Cammalleri, M | 1 |
| Dal Monte, M | 1 |
| Amato, R | 1 |
| Bagnoli, P | 1 |
| Rusciano, D | 2 |
| Tian, J | 2 |
| Song, M | 1 |
| Kaufman, DL | 2 |
| Dang, H | 1 |
| Wallner, M | 1 |
| Olsen, R | 1 |
| Russo, R | 1 |
| Adornetto, A | 1 |
| Cavaliere, F | 1 |
| Varano, GP | 1 |
| Morrone, LA | 1 |
| Corasaniti, MT | 1 |
| Bagetta, G | 1 |
| Nucci, C | 1 |
| Brener, O | 1 |
| Dunkelmann, T | 1 |
| Gremer, L | 1 |
| van Groen, T | 1 |
| Mirecka, EA | 1 |
| Kadish, I | 1 |
| Willuweit, A | 1 |
| Kutzsche, J | 1 |
| Jürgens, D | 1 |
| Rudolph, S | 1 |
| Tusche, M | 1 |
| Bongen, P | 1 |
| Pietruszka, J | 1 |
| Oesterhelt, F | 1 |
| Langen, KJ | 1 |
| Demuth, HU | 1 |
| Janssen, A | 1 |
| Hoyer, W | 1 |
| Funke, SA | 1 |
| Nagel-Steger, L | 1 |
| Willbold, D | 1 |
| Gervais, F | 1 |
| Paquette, J | 1 |
| Morissette, C | 1 |
| Krzywkowski, P | 1 |
| Yu, M | 1 |
| Azzi, M | 1 |
| Lacombe, D | 1 |
| Kong, X | 1 |
| Aman, A | 1 |
| Laurin, J | 1 |
| Szarek, WA | 1 |
| Tremblay, P | 1 |
| Golden, GT | 1 |
| Fariello, RG | 1 |
| Renner, M | 1 |
| Melki, R | 1 |
1 review available for tramiprosate and Disease Models, Animal
| Article | Year |
|---|---|
Protein aggregation and prionopathies.
Topics: Aging; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Autophagy; Biopolymers; Clinical T | 2014 |
10 other studies available for tramiprosate and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic and pharmacokinetic characterizations of an anti-amyloidogenic bis-styrylbenzene derivative for Alzheimer's disease treatment.
Topics: Administration, Oral; Alzheimer Disease; Aniline Compounds; Animals; Benzene Derivatives; Brain; Dis | 2013 |
Homotaurine ameliorates the core ASD symptomatology in VPA rats through GABAergic signaling: Role of GAD67.
Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Female; gamma-Aminobuty | 2022 |
Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Catalytic Domain; Cell Line | 2020 |
A Dietary Combination of Forskolin with Homotaurine, Spearmint and B Vitamins Protects Injured Retinal Ganglion Cells in a Rodent Model of Hypertensive Glaucoma.
Topics: Animals; Colforsin; Dietary Supplements; Disease Models, Animal; Female; Glaucoma; Intraocular Press | 2020 |
Homotaurine limits the spreading of T cell autoreactivity within the CNS and ameliorates disease in a model of multiple sclerosis.
Topics: Animals; Antigen Presentation; Antigen-Presenting Cells; Cell Proliferation; Central Nervous System; | 2021 |
Homotaurine, a safe blood-brain barrier permeable GABA
Topics: Administration, Oral; Animals; Blood-Brain Barrier; Disease Models, Animal; GABA Agonists; Mice; Mic | 2018 |
Intravitreal injection of forskolin, homotaurine, and L-carnosine affords neuroprotection to retinal ganglion cells following retinal ischemic injury.
Topics: Animals; Carnosine; Cell Survival; Colforsin; Disease Models, Animal; Drug Synergism; Glaucoma; Glyc | 2015 |
QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Carrier Proteins; Catechin; Disease Models, Anima | 2015 |
Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Brain; Cell Death; Cell | 2007 |
Penicillin spikes in rats. Limitations of a simple model for the study of anticonvulsants.
Topics: Action Potentials; Animals; Anticonvulsants; Dimethyl Sulfoxide; Disease Models, Animal; Drug Evalua | 1984 |