Page last updated: 2024-08-23

tramadol and Serotonin Syndrome

tramadol has been researched along with Serotonin Syndrome in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.17)18.2507
2000's17 (36.96)29.6817
2010's26 (56.52)24.3611
2020's2 (4.35)2.80

Authors

AuthorsStudies
Chawla, P; Raj, K; Singh, S1
Al-Khalil, M; Elson, R; Pleat, J; Sack, A1
Hardy, M; Panikkar, G1
Adroja, B; Parekh, H; Prakash, S1
Dale, W; Danovitch, I; Hassamal, S; Miotto, K1
Chevillard, L; Lagard, C; Mégarbane, B1
Ekşi, MŞ; Güngör, A; Özcan-Ekşi, EE; Pamir, MN; Tükel Turgut, FN; Turgut, VU1
May, M; Picksak, G; Stichtenoth, DO1
Belani, P; Prakash, S; Trivedi, A1
Haen, E; Wenzel-Seifert, K1
Park, SH; Stimmel, GL; Wackernah, RC1
Breivik, H1
Indrawirawan, Y; McAlees, T1
Fujimoto, Y; Funao, T; Mori, T; Nishikawa, K; Suehiro, K; Takahashi, R1
Ahad, A; Ayub, S; Ayub, Z; Shakoor, M1
Isbister, GK; Ryan, NM1
Aminiahidashti, H; Hajiaghaei, G; Mousavi, SJ; Shafiee, S1
Boettcher, BT; Cronin, DC; Gollapudy, S; Pagel, PS1
Sharma, V1
Choong, K; Ghiculescu, RA1
Buckley, N; Kelman, C; Mant, A; McGettigan, P; Mitchell, P; Pearson, SA; Ringland, C1
Homler, H1
Afshari, R; Tashakori, A1
Bhatia, N; Gombar, S1
Kadowitz, PJ; Nossaman, BD; Nossaman, VE; Ramadhyani, U1
Claudet, I; Honorat, R; Maréchal, C1
Peacock, LE; Wright, F1
Sanaei-Zadeh, H1
Gordin, VN; Lamberg, JJ1
Nelson, EM; Philbrick, AM1
Shahani, L1
Hiemke, C; Lange-Asschenfeldt, C; Mann, K; Weigmann, H1
Houlihan, DJ1
Kirchheiner, J; Kunz, D; Mahlberg, R; Sasse, J1
Garrett, PM1
Chabolla, DR; Freeman, WD1
Jones, D; Story, DA1
Carr, B; Kitson, R1
Gillman, K1
Escrivá-Moscardó, S; Llinares-Tello, F; Martínez-Mascaraque, P; Martínez-Pastor, F1
John, AP; Koloth, R1
Palazzo, M; Vizcaychipi, MP; Walker, S1
Kesavan, S; Sobala, GM1
De Heredia, JL; Gonzalez-Pinto, A; Gutierrez, M; Imaz, H; Micó, JA1
Duggal, HS; Fetchko, J1

Reviews

7 review(s) available for tramadol and Serotonin Syndrome

ArticleYear
Neurobehavioral Consequences Associated with Long Term Tramadol Utilization and Pathological Mechanisms.
    CNS & neurological disorders drug targets, 2019, Volume: 18, Issue:10

    Topics: Analgesics, Opioid; Animals; Humans; Parkinson Disease, Secondary; Seizures; Serotonin Syndrome; Tramadol

2019
Tramadol: Understanding the Risk of Serotonin Syndrome and Seizures.
    The American journal of medicine, 2018, Volume: 131, Issue:11

    Topics: Analgesics, Opioid; Anticonvulsants; Humans; Risk Factors; Seizures; Serotonin Syndrome; Tramadol

2018
Serotonin syndrome: is it a reason to avoid the use of tramadol with antidepressants?
    Journal of pharmacy practice, 2014, Volume: 27, Issue:1

    Topics: Age Factors; Antidepressive Agents; Dose-Response Relationship, Drug; Drug Interactions; Humans; Monoamine Oxidase Inhibitors; Risk Factors; Serotonin Syndrome; Tramadol

2014
Tramadol toxicity in a cat: case report and literature review of serotonin syndrome.
    Journal of feline medicine and surgery, 2014, Volume: 16, Issue:7

    Topics: Analgesics, Opioid; Animals; Australia; Cat Diseases; Cats; Dogs; Drug Overdose; Humans; Medication Errors; Serotonin Syndrome; Tramadol

2014
Advances in perioperative pain management: use of medications with dual analgesic mechanisms, tramadol & tapentadol.
    Anesthesiology clinics, 2010, Volume: 28, Issue:4

    Topics: Analgesics; Animals; Cytochrome P-450 CYP2D6; Humans; Injections, Spinal; Pain, Postoperative; Perioperative Care; Phenols; Receptors, Opioid, mu; Serotonin Syndrome; Tapentadol; Tramadol

2010
Avoiding serotonin syndrome: the nature of the interaction between tramadol and selective serotonin reuptake inhibitors.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:12

    Topics: Analgesics, Opioid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Enzyme Inhibitors; Humans; Pharmacogenetics; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Syndrome; Tramadol

2012
Serotonin syndrome and the anaesthetist.
    Anaesthesia and intensive care, 2005, Volume: 33, Issue:2

    Topics: Analgesics, Opioid; Anesthesiology; Humans; Serotonin; Serotonin Syndrome; Tramadol

2005

Other Studies

39 other study(ies) available for tramadol and Serotonin Syndrome

ArticleYear
A 5-year single-centre retrospective study of potential drug interactions in burns inpatients with psychiatric comorbidities.
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:5

    Topics: Adult; Analgesics, Opioid; Antidepressive Agents; Arrhythmias, Cardiac; Burns; Comorbidity; Drug Interactions; Female; Fentanyl; Humans; Long QT Syndrome; Male; Mental Disorders; Middle Aged; Mirtazapine; Ondansetron; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Serotonin Antagonists; Serotonin Syndrome; Torsades de Pointes; Tramadol

2020
A Case of Serotonin Syndrome in the Setting of Dextromethorphan-Based Cough Medicine, Tramadol, and Multiple Antidepressants.
    The primary care companion for CNS disorders, 2020, 03-05, Volume: 22, Issue:2

    Topics: Aged; Analgesics, Opioid; Antitussive Agents; Dextromethorphan; Female; Humans; Serotonin Agents; Serotonin Syndrome; Tramadol

2020
Serotonin syndrome in patients with headache disorders.
    BMJ case reports, 2017, Aug-07, Volume: 2017

    Topics: Acetaminophen; Adult; Amitriptyline; Analgesics; Cluster Headache; Drug Therapy, Combination; Flunarizine; Humans; Lithium; Male; Middle Aged; Migraine Disorders; Serotonin Agents; Serotonin Syndrome; Tramadol; Valproic Acid

2017
Tramadol: Distinguishing the Pathophysiology of Serotonin Syndrome and Seizures.
    The American journal of medicine, 2018, Volume: 131, Issue:11

    Topics: Analgesics, Opioid; Humans; Seizures; Serotonin Syndrome; Tramadol

2018
Serotonin Syndrome Following Tramadol and Gabapentin Use After Spine Surgery.
    World neurosurgery, 2019, Volume: 126

    Topics: Aged; Analgesics; Gabapentin; Humans; Laminectomy; Male; Pain, Postoperative; Serotonin Syndrome; Spinal Fusion; Spinal Stenosis; Tramadol

2019
[Sweating under polypharmacy with tramadol, amitriptyline and duloxetine?].
    Medizinische Monatsschrift fur Pharmazeuten, 2013, Volume: 36, Issue:5

    Topics: Amitriptyline; Analgesics, Opioid; Antidepressive Agents; Antidepressive Agents, Tricyclic; Duloxetine Hydrochloride; Humans; Polypharmacy; Serotonin Syndrome; Sweating; Thiophenes; Tramadol

2013
Headache as a presenting feature in patients with serotonin syndrome: a case series.
    Cephalalgia : an international journal of headache, 2014, Volume: 34, Issue:2

    Topics: Adult; Analgesics, Opioid; Antidepressive Agents; Female; Headache; Humans; Iatrogenic Disease; Male; Middle Aged; Serotonin; Serotonin Agents; Serotonin Syndrome; Tramadol; Young Adult

2014
[Can serotonin syndrome also be caused by tramadol administration alone?].
    Medizinische Monatsschrift fur Pharmazeuten, 2013, Volume: 36, Issue:9

    Topics: Analgesics, Opioid; Drug Synergism; Drug Therapy, Combination; Humans; Risk Factors; Serotonin Agents; Serotonin Syndrome; Tramadol

2013
Pain management discussion forum: serious interaction among frequently used drugs for chronic pain.
    Journal of pain & palliative care pharmacotherapy, 2014, Volume: 28, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Chronic Pain; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Serotonin Syndrome; Thiophenes; Tramadol

2014
Brain serotonin content regulates the manifestation of tramadol-induced seizures in rats: disparity between tramadol-induced seizure and serotonin syndrome.
    Anesthesiology, 2015, Volume: 122, Issue:1

    Topics: Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Male; Rats; Rats, Sprague-Dawley; Seizures; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Serotonin Syndrome; Tramadol

2015
Transient serotonin syndrome caused by concurrent use of tramadol and selective serotonin reuptake inhibitor.
    The American journal of case reports, 2014, Dec-19, Volume: 15

    Topics: Adult; Analgesics, Opioid; Chronic Pain; Depressive Disorder, Major; Drug Interactions; Female; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol

2014
Tramadol overdose causes seizures and respiratory depression but serotonin toxicity appears unlikely.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:6

    Topics: Adult; Analgesics, Opioid; Brain; Brain Waves; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Lung; Male; Middle Aged; New South Wales; Prognosis; Respiration; Respiratory Insufficiency; Retrospective Studies; Risk Factors; Seizures; Serotonin Syndrome; Severity of Illness Index; Tertiary Care Centers; Tramadol

2015
Tramadol Pill Alone May Cause Serotonin Syndrome.
    Chinese medical journal, 2016, Apr-05, Volume: 129, Issue:7

    Topics: Adult; Analgesics, Opioid; Humans; Male; Serotonin Syndrome; Tramadol

2016
Serotonin Syndrome Resulting From Acute Decompensation of Nonalcoholic Steatohepatitis Cirrhosis in a Patient Chronically Treated With Citalopram and Tramadol.
    Journal of cardiothoracic and vascular anesthesia, 2017, Volume: 31, Issue:4

    Topics: Citalopram; Drug Administration Schedule; Female; Humans; Middle Aged; Non-alcoholic Fatty Liver Disease; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol

2017
Tramadol-Induced Hypomania and Serotonin Syndrome.
    The primary care companion for CNS disorders, 2016, Dec-15, Volume: 18, Issue:6

    Topics: Analgesics, Opioid; Bipolar Disorder; Diagnosis, Differential; Female; Fibromyalgia; Humans; Lithium Compounds; Middle Aged; Serotonin Syndrome; Tramadol

2016
Iatrogenic neuropsychiatric syndromes.
    Australian family physician, 2008, Volume: 37, Issue:8

    Topics: Adult; Analgesics, Opioid; Female; Humans; Iatrogenic Disease; Male; Middle Aged; Psychomotor Disorders; Serotonin Syndrome; Substance Withdrawal Syndrome; Tramadol

2008
Uncovering the potential risk of serotonin toxicity in Australian veterans using pharmaceutical claims data.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:5

    Topics: Aged; Australia; Databases, Factual; Drug Prescriptions; Female; Humans; Male; Medical Errors; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Polypharmacy; Retrospective Studies; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol; Veterans; Veterans Disability Claims; Widowhood

2008
Herpes zoster: query and concern.
    Mayo Clinic proceedings, 2009, Volume: 84, Issue:7

    Topics: Analgesics, Opioid; Herpes Zoster; Humans; Neuralgia, Postherpetic; Serotonin Syndrome; Tramadol

2009
Tramadol overdose as a cause of serotonin syndrome: a case series.
    Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:4

    Topics: Adult; Demography; Drug Overdose; Female; Humans; Male; Prospective Studies; Seizures; Serotonin Syndrome; Substance-Related Disorders; Tramadol

2010
Serotonin syndrome in the perioperative period: role of tramadol.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:4

    Topics: Humans; Norepinephrine; Perioperative Care; Receptors, Opioid, mu; Serotonin Syndrome; Tramadol

2010
Serotonin syndrome induced by tramadol intoxication in an 8-month-old infant.
    Pediatric neurology, 2011, Volume: 44, Issue:1

    Topics: Analgesics, Opioid; Epistaxis; Female; Fever; Glasgow Coma Scale; Hemodynamics; Humans; Infant; Reflex; Seizures; Serotonin Syndrome; Tramadol

2011
Serotonin syndrome secondary to tramadol and citalopram.
    Age and ageing, 2011, Volume: 40, Issue:4

    Topics: Aged; Analgesics, Opioid; Citalopram; Female; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol

2011
Serotonin syndrome induced by tramadol intoxication in an 8-month-old infant.
    Pediatric neurology, 2012, Volume: 46, Issue:3

    Topics: Analgesics, Opioid; Female; Humans; Serotonin Syndrome; Tramadol

2012
Serotonin syndrome in a patient with chronic pain polypharmacy.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:8

    Topics: Adult; Amitriptyline; Anti-Allergic Agents; Antidepressive Agents; Carisoprodol; Cetirizine; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Muscle Relaxants, Central; Narcotics; Polypharmacy; Serotonin Syndrome; Thiophenes; Tramadol

2014
Tramadol precipitating serotonin syndrome in a patient on antidepressants.
    The Journal of neuropsychiatry and clinical neurosciences, 2012,Fall, Volume: 24, Issue:4

    Topics: Analgesics, Opioid; Antidepressive Agents; Bupropion; Citalopram; Depressive Disorder; Drug Therapy, Combination; Humans; Male; Middle Aged; Musculoskeletal Pain; Serotonin Syndrome; Tramadol

2012
Serotonin syndrome as a result of fluoxetine in a patient with tramadol abuse: plasma level-correlated symptomatology.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:4

    Topics: Adult; Analgesics, Opioid; Female; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol; Treatment Refusal

2002
Serotonin syndrome resulting from coadministration of tramadol, venlafaxine, and mirtazapine.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:3

    Topics: Analgesics, Opioid; Antidepressive Agents; Cyclohexanols; Depressive Disorder; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Pain; Polypharmacy; Serotonin Syndrome; Tramadol; Venlafaxine Hydrochloride

2004
Venlafaxine + tramadol: serotonin syndrome.
    Prescrire international, 2004, Volume: 13, Issue:70

    Topics: Antidepressive Agents; Cyclobutanes; Cyclohexanols; Drug Interactions; Female; France; Humans; Narcotics; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol

2004
Serotonin syndrome with tramadol and citalopram.
    The American journal of psychiatry, 2004, Volume: 161, Issue:6

    Topics: Aged; Citalopram; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Narcotics; Pain; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol

2004
Tramadol overdose and serotonin syndrome manifesting as acute right heart dysfunction.
    Anaesthesia and intensive care, 2004, Volume: 32, Issue:4

    Topics: Acute Disease; Adult; Analgesics, Opioid; Drug Overdose; Female; Humans; Hypertension, Pulmonary; Rhabdomyolysis; Serotonin Syndrome; Tramadol; Ventricular Dysfunction, Right

2004
36-Year-old woman with loss of consciousness, fever, and tachycardia.
    Mayo Clinic proceedings, 2005, Volume: 80, Issue:5

    Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Back Pain; Depression; Diagnosis, Differential; Drug Interactions; Drug Therapy, Combination; Female; Fever; Follow-Up Studies; Humans; Mianserin; Mirtazapine; Neck Pain; Serotonin Syndrome; Tachycardia; Tramadol; Unconsciousness

2005
Tramadol and severe serotonin syndrome.
    Anaesthesia, 2005, Volume: 60, Issue:9

    Topics: Aged; Amitriptyline; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Drug Interactions; Female; Humans; Serotonin Syndrome; Tramadol

2005
A response to 'Tramadol and severe serotonin syndrome'.
    Anaesthesia, 2006, Volume: 61, Issue:1

    Topics: Amitriptyline; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Drug Interactions; Humans; Serotonin Syndrome; Tramadol

2006
[Possible serotoninergic syndrome associated with coadministration of paroxetine and tramadol].
    Medicina clinica, 2007, Mar-24, Volume: 128, Issue:11

    Topics: Aged; Aged, 80 and over; Algorithms; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female; Humans; Iatrogenic Disease; Osteoarthritis; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Time Factors; Tramadol

2007
Severe serotonin toxicity and manic switch induced by combined use of tramadol and paroxetine.
    The Australian and New Zealand journal of psychiatry, 2007, Volume: 41, Issue:2

    Topics: Analgesics, Opioid; Bipolar Disorder; Depressive Disorder, Major; Drug Therapy, Combination; Female; Humans; Middle Aged; Pain; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol

2007
Serotonin syndrome triggered by tramadol.
    British journal of anaesthesia, 2007, Volume: 99, Issue:6

    Topics: Analgesics, Opioid; Humans; Male; Middle Aged; Serotonin Syndrome; Tramadol

2007
Serotonin syndrome with fluoxetine plus tramadol.
    Journal of the Royal Society of Medicine, 1999, Volume: 92, Issue:9

    Topics: Adult; Analgesics, Opioid; Drug Interactions; Female; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol

1999
Mania and tramadol-fluoxetine combination.
    The American journal of psychiatry, 2001, Volume: 158, Issue:6

    Topics: Aged; Analgesics, Opioid; Bipolar Disorder; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol

2001
Serotonin syndrome and atypical antipsychotics.
    The American journal of psychiatry, 2002, Volume: 159, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Depressive Disorder, Major; Drug Interactions; Drug Therapy, Combination; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Olanzapine; Pirenzepine; Schizophrenia; Schizotypal Personality Disorder; Serotonin Syndrome; Tramadol

2002