Page last updated: 2024-08-23

tramadol and Osteoarthritis of Knee

tramadol has been researched along with Osteoarthritis of Knee in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (33.33)29.6817
2010's16 (44.44)24.3611
2020's8 (22.22)2.80

Authors

AuthorsStudies
Beck, CG; Fernan, C; Rice, JB; Robinson, RL; Schepman, P; Silverman, S; White, AG1
Baerwald, C; Krasselt, M1
Adachi, T; Jinnouchi, M; Kawai, S; Nakano, H; Ohtani, H; Sakata, M; Sobajima, S1
Driban, JB; McAlindon, TE; Richard, MJ1
Beck, CG; Emir, B; Fernan, C; Rice, JB; Robinson, RL; Schepman, P; Silverman, S; Thakkar, S; White, A1
Cho, SK; Choi, S; Choi, WS; Im, SG; Jang, EJ; Jung, SY; Kim, H; Sung, YK1
Chen, GD; Ji, CC; Jiang, HY; Liang, T; Liu, B; Luo, ZP; Shao, YJ1
Bradbury, TL; Erens, GA; Farley, KX; Guild, GN; Schwartz, AM; Wilson, JM1
Lei, G; Li, X; Sha, T; Wang, Y; Wei, J; Xiong, Y; Zeng, C; Zhang, X1
Cronin, T; Smith, LF1
Bolognesi, MP; Goltz, DE; Green, CL; Kildow, BJ; Politzer, CS; Seyler, TM1
Driesman, A; Feng, JE; Fernandez-Madrid, I; Kaplan, D; Macaulay, W; Meere, P; Slover, J; Vigdorchik, J; Waren, DP1
Bisaillon, J; El Hindi, T; Husni, ME; Jüni, P; Maxwell, LJ; Rutjes, AW; Toupin April, K; Tugwell, P; Vincent, J; Welch, V; Wells, GA1
Bobacz, K1
Basedow, M; Esterman, A; Runciman, WB; Shanahan, EM; Williams, H1
Collins, JE; Hunter, DJ; Jordan, JM; Katz, JN; Losina, E; Paltiel, AD; Smith, SR; Solomon, DH; Suter, LG; Yelin, E1
Collins, JE; David Paltiel, A; Jordan, JM; Katz, JN; Losina, E; Smith, SR; Solomon, DH; Suter, LG; Yelin, EH1
Hiroshima, R; Ikari, K; Ishibashi, M; Kawakami, K; Koenuma, N; Mochizuki, T; Momohara, S; Shirahata, T; Takaoka, H; Yano, K1
Hao, Y; Li, X; Lu, G; Tang, Q; Yu, L1
Berggren, AC; Karlsson, M1
Bouchard, S; Kean, WF; Roderich Gossen, E1
Beals, CR; Bolognese, JA; Harman, A; Kivitz, AJ; Moskowitz, RW; Peeva, E; Smugar, SS; Taber, L1
Cavdarski, A; Hayes, DA; Jones, MA; McMeniman, PJ; McMeniman, TJ; Myers, PT; Watts, MC; Wilson, AJ; Wong, MS1
Benson, C; DeLemos, BP; Fleming, B; Gana, TJ; Pascual, ML; Rosanna, R; Xiang, J1
Cho, CS; Choi, JJ; Kim, WU; Min, JK; Park, KS; Park, SH1
Altman, RD; April, KT; Benkhalti, M; Guyatt, G; Hochberg, MC; McGowan, J; Towheed, T; Tugwell, P; Welch, V; Wells, G1
Balzarini, P; Baratelli, E; Bianchi, M; Broggini, M; Ferrario, P; Panerai, AE; Sacerdote, P1
Albert, K; Babul, N; Chipman, H; Gana, T; Noveck, R; Roth, SH1
Coffiner, M; Malonne, H; Sereno, A; Sonet, B; Vanderbist, F1
Coffiner, M; Fontaine, D; Malonne, H; Peretz, A; Sereno, A; Sonet, B; Vanderbist, F1
Fleming, RR; Gana, TJ; Janagap, CC; Pascual, ML; Schein, JR; Vorsanger, GJ; Xiang, J1
El-Husseini, T; El-Kawy, S; El-Sebai, M; Shalaby, H1
Grantinger, B; Jansson, KA; Lafolie, P; Lundblad, H; Stiller, CO; Tullberg, T; Weidenhielm, L1
Beaulieu, A; Beignot-Devalmont, P; Bouchard, S; Burch, F; Chiriac, R; Corser, B; Craciun-Nicodin, MM; Duplan, A; Fishman, R; Fortier, L; Messina, N; Radulescu, F; Robertson, S; Rodrigues, J; Sarbu, A1
Bae, SC; Choe, JY; Choi, CB; Chung, WT; Hong, YH; Ji, JD; Kang, YM; Kim, HA; Kim, TH; Lee, CK; Lee, J; Lee, JT; Lim, MK; Nam, EJ; Park, SH; Seo, YI; Sheen, DH; Shim, SC; Song, GG; Song, JS; Suh, CH; Sung, YK1
Freedman, JD; Gajria, K; Janagap-Benson, C; Kosinski, MR; Lin, P; Schein, JR1

Reviews

4 review(s) available for tramadol and Osteoarthritis of Knee

ArticleYear
Pharmaceutical treatment of osteoarthritis.
    Osteoarthritis and cartilage, 2023, Volume: 31, Issue:4

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclooxygenase 2 Inhibitors; Humans; Osteoarthritis, Knee; Pharmaceutical Preparations; Tramadol

2023
Efficacy and Safety of Tramadol for Knee or Hip Osteoarthritis: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.
    Arthritis care & research, 2023, Volume: 75, Issue:1

    Topics: Humans; Network Meta-Analysis; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Randomized Controlled Trials as Topic; Tramadol

2023
Tramadol for osteoarthritis.
    The Cochrane database of systematic reviews, 2019, 05-27, Volume: 5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Osteoarthritis; Osteoarthritis, Knee; Pain; Pain Management; Pain Measurement; Tramadol

2019
American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee.
    Arthritis care & research, 2012, Volume: 64, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Hand Joints; Humans; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Practice Guidelines as Topic; Resistance Training; Societies, Medical; Tramadol; United States; Weight Loss

2012

Trials

19 trial(s) available for tramadol and Osteoarthritis of Knee

ArticleYear
Efficacy and Safety of Tramadol Hydrochloride Twice-Daily Sustained-Release Bilayer Tablets with an Immediate-Release Component for Chronic Pain Associated with Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled, Treatment-Withdrawal Stud
    Clinical drug investigation, 2022, Volume: 42, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Chronic Pain; Delayed-Action Preparations; Double-Blind Method; Humans; Osteoarthritis, Knee; Tablets; Tramadol

2022
Tramadol hydrochloride/acetaminophen combination versus non-steroidal anti-inflammatory drug for the treatment of perioperative pain after total knee arthroplasty: A prospective, randomized, open-label clinical trial.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2016, Volume: 21, Issue:5

    Topics: Acetaminophen; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Humans; Male; Osteoarthritis, Knee; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Severity of Illness Index; Statistics, Nonparametric; Tramadol; Treatment Outcome

2016
Preoperative ropivacaine with or without tramadol for femoral nerve block in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2016, Volume: 24, Issue:2

    Topics: Aged; Aged, 80 and over; Amides; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Female; Femoral Nerve; Humans; Male; Middle Aged; Nerve Block; Osteoarthritis, Knee; Pain, Postoperative; Range of Motion, Articular; Ropivacaine; Tramadol

2016
Efficacy and safety of low-dose transdermal buprenorphine patches (5, 10, and 20 microg/h) versus prolonged-release tramadol tablets (75, 100, 150, and 200 mg) in patients with chronic osteoarthritis pain: a 12-week, randomized, open-label, controlled, pa
    Clinical therapeutics, 2009, Volume: 31, Issue:3

    Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Chronic Disease; Delayed-Action Preparations; Drug Administration Schedule; Humans; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Patient Satisfaction; Radiography; Sleep; Sweden; Tablets; Time Factors; Tramadol; Treatment Outcome

2009
Women with pain due to osteoarthritis: the efficacy and safety of a once-daily formulation of tramadol.
    Pain medicine (Malden, Mass.), 2009, Volume: 10, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Body Mass Index; Chemistry, Pharmaceutical; Delayed-Action Preparations; Double-Blind Method; Endpoint Determination; Female; Humans; Middle Aged; Osteoarthritis; Osteoarthritis, Knee; Pain; Pain Measurement; Patient Compliance; Tramadol

2009
A walking model to assess the onset of analgesia in osteoarthritis knee pain.
    Osteoarthritis and cartilage, 2010, Volume: 18, Issue:5

    Topics: Acetaminophen; Aged; Analgesics; Cross-Over Studies; Double-Blind Method; Drug Combinations; Exercise Test; Female; Humans; Male; Middle Aged; Models, Biological; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Tramadol; Walking

2010
Femoral nerve block vs fascia iliaca block for total knee arthroplasty postoperative pain control: a prospective, randomized controlled trial.
    The Journal of arthroplasty, 2010, Volume: 25, Issue:8

    Topics: Aged; Anesthetics, Intravenous; Arthroplasty, Replacement, Knee; Female; Femoral Nerve; Fentanyl; Humans; Male; Narcotics; Nerve Block; Osteoarthritis, Knee; Outcome Assessment, Health Care; Pain, Postoperative; Peripheral Nerves; Prospective Studies; Thigh; Tramadol; Treatment Outcome

2010
Tramadol hydrochloride extended-release once-daily in the treatment of osteoarthritis of the knee and/or hip: a double-blind, randomized, dose-ranging trial.
    American journal of therapeutics, 2011, Volume: 18, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Celecoxib; Cyclooxygenase 2 Inhibitors; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Knee Joint; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Placebos; Pyrazoles; Sulfonamides; Tramadol; Young Adult

2011
The efficacy of tramadol/acetaminophen combination tablets (Ultracet®) as add-on and maintenance therapy in knee osteoarthritis pain inadequately controlled by nonsteroidal anti-inflammatory drug (NSAID).
    Clinical rheumatology, 2012, Volume: 31, Issue:2

    Topics: Acetaminophen; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Tramadol; Treatment Outcome

2012
Effects of tramadol on synovial fluid concentrations of substance P and interleukin-6 in patients with knee osteoarthritis: comparison with paracetamol.
    International immunopharmacology, 2003, Volume: 3, Issue:13-14

    Topics: Acetaminophen; Administration, Oral; Aged; Double-Blind Method; Female; Humans; Interleukin-6; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Prospective Studies; Substance P; Synovial Fluid; Time Factors; Tramadol

2003
Efficacy and safety of extended-release, once-daily tramadol in chronic pain: a randomized 12-week clinical trial in osteoarthritis of the knee.
    Journal of pain and symptom management, 2004, Volume: 28, Issue:1

    Topics: Aged; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Tramadol; Treatment Outcome

2004
Efficacy and tolerability of sustained-release tramadol in the treatment of symptomatic osteoarthritis of the hip or knee: a multicenter, randomized, double-blind, placebo-controlled study.
    Clinical therapeutics, 2004, Volume: 26, Issue:11

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Tramadol

2004
Long-term tolerability of tramadol LP, a new once-daily formulation, in patients with osteoarthritis or low back pain.
    Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:2

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Low Back Pain; Male; Nausea; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain, Intractable; Patient Satisfaction; Radiography; Tramadol; Treatment Outcome; Vomiting

2005
Extended-release tramadol in the treatment of osteoarthritis: a multicenter, randomized, double-blind, placebo-controlled clinical trial.
    Current medical research and opinion, 2006, Volume: 22, Issue:7

    Topics: Adult; Aged; Analgesics, Opioid; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Measurement; Tramadol

2006
Microcurrent skin patches for postoperative pain control in total knee arthroplasty: a pilot study.
    International orthopaedics, 2007, Volume: 31, Issue:2

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Case-Control Studies; Humans; Injections, Intramuscular; Osteoarthritis, Knee; Pain Measurement; Pain, Postoperative; Pilot Projects; Tramadol; Wound Healing

2007
The addition of tramadol to morphine via patient-controlled analgesia does not lead to better post-operative pain relief after total knee arthroplasty.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:3

    Topics: Adult; Aged; Algorithms; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Osteoarthritis, Knee; Pain Measurement; Pain, Postoperative; Statistics, Nonparametric; Tramadol; Treatment Outcome

2007
A comparison of the analgesic efficacy of Tramadol Contramid OAD versus placebo in patients with pain due to osteoarthritis.
    Journal of pain and symptom management, 2007, Volume: 34, Issue:3

    Topics: Aged; Analgesics, Opioid; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Tramadol; Treatment Outcome

2007
A 2-week, multicenter, randomized, double-blind, double-dummy, add-on study of the effects of titration on tolerability of tramadol/acetaminophen combination tablet in Korean adults with knee osteoarthritis pain.
    Clinical therapeutics, 2007, Volume: 29, Issue:7

    Topics: Acetaminophen; Adult; Aged; Analgesics; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Korea; Male; Middle Aged; Osteoarthritis, Knee; Pain; Patient Dropouts; Tramadol

2007
Functionality and health-status benefits associated with reduction of osteoarthritis pain.
    Current medical research and opinion, 2008, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Chronic Disease; Cross-Sectional Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Health Status; Humans; Male; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Patient Satisfaction; Probability; Prognosis; Quality of Life; Recovery of Function; Reference Values; Severity of Illness Index; Tramadol; Treatment Outcome

2008

Other Studies

13 other study(ies) available for tramadol and Osteoarthritis of Knee

ArticleYear
Clinical and economic burden of prescribing tramadol and other opioids for patients with osteoarthritis in a commercially insured population in the United States.
    Pain, 2022, Jan-01, Volume: 163, Issue:1

    Topics: Analgesics, Opioid; Financial Stress; Humans; Osteoarthritis, Hip; Osteoarthritis, Knee; Retrospective Studies; Tramadol; United States

2022
[Osteoarthritis: what's new?]
    Deutsche medizinische Wochenschrift (1946), 2022, Volume: 147, Issue:6

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Humans; Osteoarthritis, Knee; Overweight; Tramadol

2022
Prescription opioid utilization patterns, and associated outcomes, among privately insured patients prescribed opioids to manage pain associated with osteoarthritis.
    Current medical research and opinion, 2023, Volume: 39, Issue:8

    Topics: Adult; Analgesics, Opioid; Humans; Insurance, Health; Osteoarthritis; Osteoarthritis, Knee; Pain; Prescriptions; Tramadol

2023
Factors related to the use of opioids as early treatment in patients with knee osteoarthritis.
    Arthritis research & therapy, 2019, 11-04, Volume: 21, Issue:1

    Topics: Aged; Analgesics, Opioid; Cohort Studies; Databases, Factual; Depression; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Republic of Korea; Sex Factors; Tramadol; Treatment Outcome

2019
Microstructure and mechanical properties of subchondral bone are negatively regulated by tramadol in osteoarthritis in mice.
    Bioscience reports, 2020, 09-30, Volume: 40, Issue:9

    Topics: Analgesics, Opioid; Animals; Bone and Bones; Bone Remodeling; Cartilage; Disease Models, Animal; Elastic Modulus; Male; Menisci, Tibial; Mice, Inbred C57BL; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Osteoarthritis, Knee; Synovitis; Tramadol; X-Ray Microtomography

2020
The impact of preoperative tramadol-only use on outcomes following total knee arthroplasty - Is tramadol different than traditional opioids?
    The Knee, 2021, Volume: 28

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain, Postoperative; Preoperative Care; Reoperation; Retrospective Studies; Risk Factors; Tramadol

2021
Tramadol-induced hypoglycaemia.
    Postgraduate medical journal, 2018, Volume: 94, Issue:1108

    Topics: Analgesics, Opioid; Diabetes Mellitus, Type 2; Humans; Hypoglycemia; Male; Middle Aged; Osteoarthritis, Knee; Pain; Tramadol; Treatment Outcome

2018
Trends in Opioid Utilization Before and After Total Knee Arthroplasty.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:7S

    Topics: Adult; Aged; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Databases, Factual; Female; Humans; Male; Middle Aged; Odds Ratio; Opioid-Related Disorders; Osteoarthritis, Knee; Pain Management; Pain, Postoperative; Postoperative Period; Retrospective Studies; Risk Factors; Tramadol

2018
Tramadol in Knee Osteoarthritis: Does Preoperative Use Affect Patient-Reported Outcomes After Total Knee Arthroplasty?
    The Journal of arthroplasty, 2019, Volume: 34, Issue:8

    Topics: Aged; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Female; Humans; Knee Joint; Male; Middle Aged; Narcotics; Osteoarthritis, Knee; Outcome Assessment, Health Care; Patient Reported Outcome Measures; Postoperative Period; Retrospective Studies; Tramadol; Treatment Outcome

2019
Pharmacologic treatment of hand-, knee- and hip-osteoarthritis.
    Wiener medizinische Wochenschrift (1946), 2013, Volume: 163, Issue:9-10

    Topics: Acetaminophen; Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chondroitin; Combined Modality Therapy; Cyclooxygenase 2 Inhibitors; Glucosamine; Hand Joints; Humans; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Tramadol

2013
Australian GP management of osteoarthritis following the release of the RACGP guideline for the non-surgical management of hip and knee osteoarthritis.
    BMC research notes, 2015, Oct-05, Volume: 8

    Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Australia; Codeine; Disease Management; Drug Combinations; Female; General Practitioners; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Practice Guidelines as Topic; Practice Patterns, Physicians'; Risk; Surveys and Questionnaires; Tramadol

2015
Cost-effectiveness of nonsteroidal anti-inflammatory drugs and opioids in the treatment of knee osteoarthritis in older patients with multiple comorbidities.
    Osteoarthritis and cartilage, 2016, Volume: 24, Issue:3

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Comorbidity; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Health Services Research; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nonprescription Drugs; Osteoarthritis, Knee; Pain; Pain Measurement; Proton Pump Inhibitors; Quality-Adjusted Life Years; Sensitivity and Specificity; Tramadol; Treatment Outcome; United States

2016
Cost-Effectiveness of Tramadol and Oxycodone in the Treatment of Knee Osteoarthritis.
    Arthritis care & research, 2017, Volume: 69, Issue:2

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Computer Simulation; Cost-Benefit Analysis; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Oxycodone; Tramadol

2017