Page last updated: 2024-08-23

tramadol and Osteoarthritis, Knee

tramadol has been researched along with Osteoarthritis, Knee in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (33.33)29.6817
2010's16 (44.44)24.3611
2020's8 (22.22)2.80

Authors

AuthorsStudies
Beck, CG; Fernan, C; Rice, JB; Robinson, RL; Schepman, P; Silverman, S; White, AG1
Baerwald, C; Krasselt, M1
Adachi, T; Jinnouchi, M; Kawai, S; Nakano, H; Ohtani, H; Sakata, M; Sobajima, S1
Driban, JB; McAlindon, TE; Richard, MJ1
Beck, CG; Emir, B; Fernan, C; Rice, JB; Robinson, RL; Schepman, P; Silverman, S; Thakkar, S; White, A1
Cho, SK; Choi, S; Choi, WS; Im, SG; Jang, EJ; Jung, SY; Kim, H; Sung, YK1
Chen, GD; Ji, CC; Jiang, HY; Liang, T; Liu, B; Luo, ZP; Shao, YJ1
Bradbury, TL; Erens, GA; Farley, KX; Guild, GN; Schwartz, AM; Wilson, JM1
Lei, G; Li, X; Sha, T; Wang, Y; Wei, J; Xiong, Y; Zeng, C; Zhang, X1
Cronin, T; Smith, LF1
Bolognesi, MP; Goltz, DE; Green, CL; Kildow, BJ; Politzer, CS; Seyler, TM1
Driesman, A; Feng, JE; Fernandez-Madrid, I; Kaplan, D; Macaulay, W; Meere, P; Slover, J; Vigdorchik, J; Waren, DP1
Bisaillon, J; El Hindi, T; Husni, ME; Jüni, P; Maxwell, LJ; Rutjes, AW; Toupin April, K; Tugwell, P; Vincent, J; Welch, V; Wells, GA1
Bobacz, K1
Basedow, M; Esterman, A; Runciman, WB; Shanahan, EM; Williams, H1
Collins, JE; Hunter, DJ; Jordan, JM; Katz, JN; Losina, E; Paltiel, AD; Smith, SR; Solomon, DH; Suter, LG; Yelin, E1
Collins, JE; David Paltiel, A; Jordan, JM; Katz, JN; Losina, E; Smith, SR; Solomon, DH; Suter, LG; Yelin, EH1
Hiroshima, R; Ikari, K; Ishibashi, M; Kawakami, K; Koenuma, N; Mochizuki, T; Momohara, S; Shirahata, T; Takaoka, H; Yano, K1
Hao, Y; Li, X; Lu, G; Tang, Q; Yu, L1
Berggren, AC; Karlsson, M1
Bouchard, S; Kean, WF; Roderich Gossen, E1
Beals, CR; Bolognese, JA; Harman, A; Kivitz, AJ; Moskowitz, RW; Peeva, E; Smugar, SS; Taber, L1
Cavdarski, A; Hayes, DA; Jones, MA; McMeniman, PJ; McMeniman, TJ; Myers, PT; Watts, MC; Wilson, AJ; Wong, MS1
Benson, C; DeLemos, BP; Fleming, B; Gana, TJ; Pascual, ML; Rosanna, R; Xiang, J1
Cho, CS; Choi, JJ; Kim, WU; Min, JK; Park, KS; Park, SH1
Altman, RD; April, KT; Benkhalti, M; Guyatt, G; Hochberg, MC; McGowan, J; Towheed, T; Tugwell, P; Welch, V; Wells, G1
Balzarini, P; Baratelli, E; Bianchi, M; Broggini, M; Ferrario, P; Panerai, AE; Sacerdote, P1
Albert, K; Babul, N; Chipman, H; Gana, T; Noveck, R; Roth, SH1
Coffiner, M; Malonne, H; Sereno, A; Sonet, B; Vanderbist, F1
Coffiner, M; Fontaine, D; Malonne, H; Peretz, A; Sereno, A; Sonet, B; Vanderbist, F1
Fleming, RR; Gana, TJ; Janagap, CC; Pascual, ML; Schein, JR; Vorsanger, GJ; Xiang, J1
El-Husseini, T; El-Kawy, S; El-Sebai, M; Shalaby, H1
Grantinger, B; Jansson, KA; Lafolie, P; Lundblad, H; Stiller, CO; Tullberg, T; Weidenhielm, L1
Beaulieu, A; Beignot-Devalmont, P; Bouchard, S; Burch, F; Chiriac, R; Corser, B; Craciun-Nicodin, MM; Duplan, A; Fishman, R; Fortier, L; Messina, N; Radulescu, F; Robertson, S; Rodrigues, J; Sarbu, A1
Bae, SC; Choe, JY; Choi, CB; Chung, WT; Hong, YH; Ji, JD; Kang, YM; Kim, HA; Kim, TH; Lee, CK; Lee, J; Lee, JT; Lim, MK; Nam, EJ; Park, SH; Seo, YI; Sheen, DH; Shim, SC; Song, GG; Song, JS; Suh, CH; Sung, YK1
Freedman, JD; Gajria, K; Janagap-Benson, C; Kosinski, MR; Lin, P; Schein, JR1

Reviews

4 review(s) available for tramadol and Osteoarthritis, Knee

ArticleYear
Pharmaceutical treatment of osteoarthritis.
    Osteoarthritis and cartilage, 2023, Volume: 31, Issue:4

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclooxygenase 2 Inhibitors; Humans; Osteoarthritis, Knee; Pharmaceutical Preparations; Tramadol

2023
Efficacy and Safety of Tramadol for Knee or Hip Osteoarthritis: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.
    Arthritis care & research, 2023, Volume: 75, Issue:1

    Topics: Humans; Network Meta-Analysis; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Randomized Controlled Trials as Topic; Tramadol

2023
Tramadol for osteoarthritis.
    The Cochrane database of systematic reviews, 2019, 05-27, Volume: 5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Osteoarthritis; Osteoarthritis, Knee; Pain; Pain Management; Pain Measurement; Tramadol

2019
American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee.
    Arthritis care & research, 2012, Volume: 64, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Hand Joints; Humans; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Practice Guidelines as Topic; Resistance Training; Societies, Medical; Tramadol; United States; Weight Loss

2012

Trials

19 trial(s) available for tramadol and Osteoarthritis, Knee

ArticleYear
Efficacy and Safety of Tramadol Hydrochloride Twice-Daily Sustained-Release Bilayer Tablets with an Immediate-Release Component for Chronic Pain Associated with Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled, Treatment-Withdrawal Stud
    Clinical drug investigation, 2022, Volume: 42, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Chronic Pain; Delayed-Action Preparations; Double-Blind Method; Humans; Osteoarthritis, Knee; Tablets; Tramadol

2022
Tramadol hydrochloride/acetaminophen combination versus non-steroidal anti-inflammatory drug for the treatment of perioperative pain after total knee arthroplasty: A prospective, randomized, open-label clinical trial.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2016, Volume: 21, Issue:5

    Topics: Acetaminophen; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Humans; Male; Osteoarthritis, Knee; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Severity of Illness Index; Statistics, Nonparametric; Tramadol; Treatment Outcome

2016
Preoperative ropivacaine with or without tramadol for femoral nerve block in total knee arthroplasty.
    Journal of orthopaedic surgery (Hong Kong), 2016, Volume: 24, Issue:2

    Topics: Aged; Aged, 80 and over; Amides; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Female; Femoral Nerve; Humans; Male; Middle Aged; Nerve Block; Osteoarthritis, Knee; Pain, Postoperative; Range of Motion, Articular; Ropivacaine; Tramadol

2016
Efficacy and safety of low-dose transdermal buprenorphine patches (5, 10, and 20 microg/h) versus prolonged-release tramadol tablets (75, 100, 150, and 200 mg) in patients with chronic osteoarthritis pain: a 12-week, randomized, open-label, controlled, pa
    Clinical therapeutics, 2009, Volume: 31, Issue:3

    Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Chronic Disease; Delayed-Action Preparations; Drug Administration Schedule; Humans; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Patient Satisfaction; Radiography; Sleep; Sweden; Tablets; Time Factors; Tramadol; Treatment Outcome

2009
Women with pain due to osteoarthritis: the efficacy and safety of a once-daily formulation of tramadol.
    Pain medicine (Malden, Mass.), 2009, Volume: 10, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Body Mass Index; Chemistry, Pharmaceutical; Delayed-Action Preparations; Double-Blind Method; Endpoint Determination; Female; Humans; Middle Aged; Osteoarthritis; Osteoarthritis, Knee; Pain; Pain Measurement; Patient Compliance; Tramadol

2009
A walking model to assess the onset of analgesia in osteoarthritis knee pain.
    Osteoarthritis and cartilage, 2010, Volume: 18, Issue:5

    Topics: Acetaminophen; Aged; Analgesics; Cross-Over Studies; Double-Blind Method; Drug Combinations; Exercise Test; Female; Humans; Male; Middle Aged; Models, Biological; Naproxen; Osteoarthritis, Knee; Pain; Pain Measurement; Tramadol; Walking

2010
Femoral nerve block vs fascia iliaca block for total knee arthroplasty postoperative pain control: a prospective, randomized controlled trial.
    The Journal of arthroplasty, 2010, Volume: 25, Issue:8

    Topics: Aged; Anesthetics, Intravenous; Arthroplasty, Replacement, Knee; Female; Femoral Nerve; Fentanyl; Humans; Male; Narcotics; Nerve Block; Osteoarthritis, Knee; Outcome Assessment, Health Care; Pain, Postoperative; Peripheral Nerves; Prospective Studies; Thigh; Tramadol; Treatment Outcome

2010
Tramadol hydrochloride extended-release once-daily in the treatment of osteoarthritis of the knee and/or hip: a double-blind, randomized, dose-ranging trial.
    American journal of therapeutics, 2011, Volume: 18, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Celecoxib; Cyclooxygenase 2 Inhibitors; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Knee Joint; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Placebos; Pyrazoles; Sulfonamides; Tramadol; Young Adult

2011
The efficacy of tramadol/acetaminophen combination tablets (Ultracet®) as add-on and maintenance therapy in knee osteoarthritis pain inadequately controlled by nonsteroidal anti-inflammatory drug (NSAID).
    Clinical rheumatology, 2012, Volume: 31, Issue:2

    Topics: Acetaminophen; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Tramadol; Treatment Outcome

2012
Effects of tramadol on synovial fluid concentrations of substance P and interleukin-6 in patients with knee osteoarthritis: comparison with paracetamol.
    International immunopharmacology, 2003, Volume: 3, Issue:13-14

    Topics: Acetaminophen; Administration, Oral; Aged; Double-Blind Method; Female; Humans; Interleukin-6; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Prospective Studies; Substance P; Synovial Fluid; Time Factors; Tramadol

2003
Efficacy and safety of extended-release, once-daily tramadol in chronic pain: a randomized 12-week clinical trial in osteoarthritis of the knee.
    Journal of pain and symptom management, 2004, Volume: 28, Issue:1

    Topics: Aged; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Tramadol; Treatment Outcome

2004
Efficacy and tolerability of sustained-release tramadol in the treatment of symptomatic osteoarthritis of the hip or knee: a multicenter, randomized, double-blind, placebo-controlled study.
    Clinical therapeutics, 2004, Volume: 26, Issue:11

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Tramadol

2004
Long-term tolerability of tramadol LP, a new once-daily formulation, in patients with osteoarthritis or low back pain.
    Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:2

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Low Back Pain; Male; Nausea; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain, Intractable; Patient Satisfaction; Radiography; Tramadol; Treatment Outcome; Vomiting

2005
Extended-release tramadol in the treatment of osteoarthritis: a multicenter, randomized, double-blind, placebo-controlled clinical trial.
    Current medical research and opinion, 2006, Volume: 22, Issue:7

    Topics: Adult; Aged; Analgesics, Opioid; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Measurement; Tramadol

2006
Microcurrent skin patches for postoperative pain control in total knee arthroplasty: a pilot study.
    International orthopaedics, 2007, Volume: 31, Issue:2

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Case-Control Studies; Humans; Injections, Intramuscular; Osteoarthritis, Knee; Pain Measurement; Pain, Postoperative; Pilot Projects; Tramadol; Wound Healing

2007
The addition of tramadol to morphine via patient-controlled analgesia does not lead to better post-operative pain relief after total knee arthroplasty.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:3

    Topics: Adult; Aged; Algorithms; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Osteoarthritis, Knee; Pain Measurement; Pain, Postoperative; Statistics, Nonparametric; Tramadol; Treatment Outcome

2007
A comparison of the analgesic efficacy of Tramadol Contramid OAD versus placebo in patients with pain due to osteoarthritis.
    Journal of pain and symptom management, 2007, Volume: 34, Issue:3

    Topics: Aged; Analgesics, Opioid; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Tramadol; Treatment Outcome

2007
A 2-week, multicenter, randomized, double-blind, double-dummy, add-on study of the effects of titration on tolerability of tramadol/acetaminophen combination tablet in Korean adults with knee osteoarthritis pain.
    Clinical therapeutics, 2007, Volume: 29, Issue:7

    Topics: Acetaminophen; Adult; Aged; Analgesics; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Korea; Male; Middle Aged; Osteoarthritis, Knee; Pain; Patient Dropouts; Tramadol

2007
Functionality and health-status benefits associated with reduction of osteoarthritis pain.
    Current medical research and opinion, 2008, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Chronic Disease; Cross-Sectional Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Health Status; Humans; Male; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Patient Satisfaction; Probability; Prognosis; Quality of Life; Recovery of Function; Reference Values; Severity of Illness Index; Tramadol; Treatment Outcome

2008

Other Studies

13 other study(ies) available for tramadol and Osteoarthritis, Knee

ArticleYear
Clinical and economic burden of prescribing tramadol and other opioids for patients with osteoarthritis in a commercially insured population in the United States.
    Pain, 2022, Jan-01, Volume: 163, Issue:1

    Topics: Analgesics, Opioid; Financial Stress; Humans; Osteoarthritis, Hip; Osteoarthritis, Knee; Retrospective Studies; Tramadol; United States

2022
[Osteoarthritis: what's new?]
    Deutsche medizinische Wochenschrift (1946), 2022, Volume: 147, Issue:6

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Humans; Osteoarthritis, Knee; Overweight; Tramadol

2022
Prescription opioid utilization patterns, and associated outcomes, among privately insured patients prescribed opioids to manage pain associated with osteoarthritis.
    Current medical research and opinion, 2023, Volume: 39, Issue:8

    Topics: Adult; Analgesics, Opioid; Humans; Insurance, Health; Osteoarthritis; Osteoarthritis, Knee; Pain; Prescriptions; Tramadol

2023
Factors related to the use of opioids as early treatment in patients with knee osteoarthritis.
    Arthritis research & therapy, 2019, 11-04, Volume: 21, Issue:1

    Topics: Aged; Analgesics, Opioid; Cohort Studies; Databases, Factual; Depression; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Republic of Korea; Sex Factors; Tramadol; Treatment Outcome

2019
Microstructure and mechanical properties of subchondral bone are negatively regulated by tramadol in osteoarthritis in mice.
    Bioscience reports, 2020, 09-30, Volume: 40, Issue:9

    Topics: Analgesics, Opioid; Animals; Bone and Bones; Bone Remodeling; Cartilage; Disease Models, Animal; Elastic Modulus; Male; Menisci, Tibial; Mice, Inbred C57BL; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Osteoarthritis, Knee; Synovitis; Tramadol; X-Ray Microtomography

2020
The impact of preoperative tramadol-only use on outcomes following total knee arthroplasty - Is tramadol different than traditional opioids?
    The Knee, 2021, Volume: 28

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain, Postoperative; Preoperative Care; Reoperation; Retrospective Studies; Risk Factors; Tramadol

2021
Tramadol-induced hypoglycaemia.
    Postgraduate medical journal, 2018, Volume: 94, Issue:1108

    Topics: Analgesics, Opioid; Diabetes Mellitus, Type 2; Humans; Hypoglycemia; Male; Middle Aged; Osteoarthritis, Knee; Pain; Tramadol; Treatment Outcome

2018
Trends in Opioid Utilization Before and After Total Knee Arthroplasty.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:7S

    Topics: Adult; Aged; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Databases, Factual; Female; Humans; Male; Middle Aged; Odds Ratio; Opioid-Related Disorders; Osteoarthritis, Knee; Pain Management; Pain, Postoperative; Postoperative Period; Retrospective Studies; Risk Factors; Tramadol

2018
Tramadol in Knee Osteoarthritis: Does Preoperative Use Affect Patient-Reported Outcomes After Total Knee Arthroplasty?
    The Journal of arthroplasty, 2019, Volume: 34, Issue:8

    Topics: Aged; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Female; Humans; Knee Joint; Male; Middle Aged; Narcotics; Osteoarthritis, Knee; Outcome Assessment, Health Care; Patient Reported Outcome Measures; Postoperative Period; Retrospective Studies; Tramadol; Treatment Outcome

2019
Pharmacologic treatment of hand-, knee- and hip-osteoarthritis.
    Wiener medizinische Wochenschrift (1946), 2013, Volume: 163, Issue:9-10

    Topics: Acetaminophen; Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chondroitin; Combined Modality Therapy; Cyclooxygenase 2 Inhibitors; Glucosamine; Hand Joints; Humans; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Tramadol

2013
Australian GP management of osteoarthritis following the release of the RACGP guideline for the non-surgical management of hip and knee osteoarthritis.
    BMC research notes, 2015, Oct-05, Volume: 8

    Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Australia; Codeine; Disease Management; Drug Combinations; Female; General Practitioners; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Practice Guidelines as Topic; Practice Patterns, Physicians'; Risk; Surveys and Questionnaires; Tramadol

2015
Cost-effectiveness of nonsteroidal anti-inflammatory drugs and opioids in the treatment of knee osteoarthritis in older patients with multiple comorbidities.
    Osteoarthritis and cartilage, 2016, Volume: 24, Issue:3

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Comorbidity; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Health Services Research; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nonprescription Drugs; Osteoarthritis, Knee; Pain; Pain Measurement; Proton Pump Inhibitors; Quality-Adjusted Life Years; Sensitivity and Specificity; Tramadol; Treatment Outcome; United States

2016
Cost-Effectiveness of Tramadol and Oxycodone in the Treatment of Knee Osteoarthritis.
    Arthritis care & research, 2017, Volume: 69, Issue:2

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Computer Simulation; Cost-Benefit Analysis; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Oxycodone; Tramadol

2017