Page last updated: 2024-08-23

tramadol and Chronic Pain

tramadol has been researched along with Chronic Pain in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's53 (75.71)24.3611
2020's17 (24.29)2.80

Authors

AuthorsStudies
Adachi, T; Jinnouchi, M; Kawai, S; Nakano, H; Ohtani, H; Sakata, M; Sobajima, S1
Fox, MR; Halasz, V; Knittel, L1
Acharya, M; Dayer, L; Hayes, CJ; Li, C; Martin, BC; Painter, JT1
Besic, N; Dolzan, V; Goricar, K; Strazisar, B; Vidic, Z1
Abraham, C; Alleyne, S; Balasubramanian, S; Betteley, L; Booth, K; Carnes, D; Eldabe, S; Furlan, AD; Haywood, KL; Iglesias-Urrutia, CP; Krishnan, S; Lall, R; Manca, A; Mistry, D; Newton, S; Nichols, V; Noyes, J; Padfield, E; Rahman, A; Sandhu, HK; Seers, K; Shaw, J; Tang, NKY; Taylor, SJC; Tysall, C; Underwood, M1
Barrachina, J; Carvajal, C; Escorial, M; Margarit, C; Morales, D; Muriel, J; Peiró, AM1
McCarberg, B1
Barakji, J; Feinberg, JB; Gluud, C; Jakobsen, JC; Korang, SK; Maagaard, M; Mathiesen, O1
Ceci, A; Della Pasqua, O; Felisi, M; Healy, P; Verrest, L1
Jeong, KH; Jung, SY; Koo, H; Lee, MT; Lee, S; Seon, JY; You, SH1
Abrahamsen, B; Ernst, MT; Hansen, CA; Stougaard, M1
Degenhardt, L; Gisev, N; Hall, WD; Roxburgh, A1
Bolster, MB; Choi, HK; Dubreuil, M; Lane, NE; Lei, G; Lu, N; Misra, D; Wei, J; Zeng, C; Zhang, Y1
Batistaki, C; Chrona, E; Gazouli, M; Kostopanagiotou, G; Kostroglou, A1
Doostmohammadi, M; Rahimi, HR1
Amaya, F; Ishikawa, T; Kanbayashi, Y; Tabuchi, Y; Taguchi, T; Takayama, K; Ueno, H1
Desmeules, J; Piguet, V; Rollason, V; Roulet, L1
Hall, C; Hotham, E; Lloyd, RA; Suppiah, V; Williams, M1
Amescua-Garcia, C; Berenguel Cook, MDR; Bonilla Sierra, P; Campos Kraychete, D; Colimon, F; Flores Cantisani, JA; Guerrero, C; Guillén Núñez, MDR; Hernández-Castro, JJ; Jreige Iskandar, A; Lara-Solares, A; Lech, O; Rico, MA; Santos Garcia, JB; Sempértegui Gallegos, M1
Berrocoso, E; Bravo, L; Mico, JA1
de C Williams, AC; Donaldson, LJ; Mordecai, L; Reynolds, C1
Ekelin, E; Hansson, A1
Ashrafi, H; Azadi, A; Barati, M; Mohammadi Samani, S; Pourtalebi Jahromi, L1
Ardid, D; Authier, N; Chenaf, C; Delage, N; Delorme, J; Eschalier, A; Kaboré, JL; Mulliez, A; Pereira, B; Zenut, M1
Birke, H; Clausen, T; Ekholm, O; Fredheim, O; Sjøgren, P; Skurtveit, S1
Ajo, R; Esteban, MD; Inda, MD; Margarit, C; Muriel, J; Peiró, AM; Planelles, B; Sastre, Y1
Baldacchino, A; Balfour, DJ; Matthews, K; Tolomeo, S1
Bajaj, S; Kumar, MS; Subedi, M; Yc, M1
Chaves, RHF; Furlaneto, IP; Lima, AR; Oliveira, CP; Penha, NEAD; Rodrigues, EM; Santos, DASD; Silva, RC; Souza, CC; Teixeira, RKC1
Alberti, C; Bonifazi, D; Ceci, A; de Leeuw, TG; de Wildt, SN; Della Pasqua, O; Felisi, M; Kaguelidou, F; Le Roux, E; Lundin, R; Mangiarini, L; Tibboel, D1
Baltazar-Martins, JG; Carreras, D; Del Coso, J; Muñoz, G; Muñoz-Guerra, J; Plata, MDM1
Dasgupta, N; Jonsson Funk, M; Young, JC1
Fantoni, DT; Flôr, PB; Ida, KK; Yazbek, KV1
Kato, J; Yokotsuka, S1
Farquhar-Smith, P; Gubbay, A1
Becquemont, L; Bertin, P; Corruble, E; Derumeaux, G; Falissard, B; Forette, F; Hanon, O; Pinget, M1
Lee, CS; Lee, JH1
Homan, T; Kaneko, K; Oka, M; Okamoto, K; Oyama, T; Umehara, M1
Boonstra, AM; Dijkstra, PU; Geertzen, JH; Molmans, BH; Reneman, MF; Schiphorst Preuper, HR; van Wijhe, M1
Breivik, H1
Pergolizzi, JV; Raffa, RB; Smith, HS; Tallarida, RJ; Taylor, R1
Lehmann, U; Richter, U; Waldmann-Rex, S1
Bernardy, K; Häuser, W; Maier, C1
Ahad, A; Ayub, S; Ayub, Z; Shakoor, M1
Akehurst, R; Dunlop, W; Hirst, A; Hirst, M; Knight, C1
Allegri, M; Ambrosoli, AL; Braschi, A; Bugada, D; Fanelli, G; Klersy, C; Lavand'homme, P; Saccani Jotti, GM1
Fujie, M; Kawai, K; Ogawa, Y; Suzuki, J; Yajima, T; Yokomori, J; Yoshizawa, K1
Antoniów, M; Grześkowiak, E; Kus, K; Nowakowska, E; Ratajczak, P; Szkutnik-Fiedler, D1
Fujie, M; Kawai, K; Kobayashi, H; Ogawa, Y; Yajima, T; Yoshizawa, K1
Allegri, M; Ambrosoli, AL; Bugada, D; Cappelleri, G; Fanelli, G; Lavand'homme, P; Meschi, T; Saccani Jotti, GM1
Dogan, C; Eerdekens, M; Etropolski, M; Karcher, K; Koch, ED; Kosturski, H; Kress, HG; Steup, A1
Brown, EE; Davies, S1
Authier, N; Chenaf, C; Delage, N; Delorme, J; Eschalier, A; Kabore, JL; Mulliez, A; Pereira, B; Roche, L1
Crow, JM1
Nishida, K; Ozaki, T; Takei, Y; Tanaka, M; Tetsunaga, T1
Gurwitz, JH; Hume, AL; Lapane, KL; Pimentel, CB; Tjia, J1
Blanco, K; Cho, AK; Khalil, MA; Miotto, K; Rawson, R; Sasaki, JD1
Onan, B; Selcuk, I; Sen, H; Turan, A; Ucak, A; Yilmaz, AT1
Chan, S; Debono, M; Jones, TH; Rolfe, C1
El-Feky, G; Kamel, R; Mahmoud, A1
Kahan, M; Mailis-Gagnon, A; Srivastava, A; Wilson, L1
Goetghebeur, MM; Khoury, H; Oh, P; Papastavros, T; Rindress, D; Tony, M; Wagner, M1
Kohno, T; Obata, H1
Camposarcone, N; Di Castelnuovo, A; Garofano, A; Grimani, V; Ianigro, G; Liberatoscioli, G; Nardi, LF; Rossi, M1
Gordin, VN; Lamberg, JJ1
Mueller-Schwefe, GH; Terhaag, B; Uberall, MA1
Hsieh, YJ; Hsu, SK; Lin, CJ; Yeh, CC1
Guerra, L; Pellicano, R1
Cho, SY; Choi, JI; Kim, WM; Lee, HG; Lee, SH; Yoon, MH1

Reviews

12 review(s) available for tramadol and Chronic Pain

ArticleYear
ADME and toxicity considerations for tramadol: from basic research to clinical implications.
    Expert opinion on drug metabolism & toxicology, 2020, Volume: 16, Issue:7

    Topics: Analgesics, Opioid; Animals; Chronic Pain; Drug Interactions; Drug Overdose; Humans; Quality of Life; Tramadol

2020
Pharmacogenomics and Patient Treatment Parameters to Opioid Treatment in Chronic Pain: A Focus on Morphine, Oxycodone, Tramadol, and Fentanyl.
    Pain medicine (Malden, Mass.), 2017, Dec-01, Volume: 18, Issue:12

    Topics: Analgesics, Opioid; Chronic Pain; Fentanyl; Humans; Morphine; Oxycodone; Pharmacogenomic Testing; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Tramadol

2017
The role of tramadol in pain management in Latin America: a report by the Change Pain Latin America Advisory Panel.
    Current medical research and opinion, 2017, Volume: 33, Issue:9

    Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cancer Pain; Chronic Pain; Humans; Latin America; Pain Management; Tramadol

2017
Discovery and development of tramadol for the treatment of pain.
    Expert opinion on drug discovery, 2017, Volume: 12, Issue:12

    Topics: Acute Pain; Analgesics, Opioid; Animals; Chronic Pain; Drug Design; Humans; Severity of Illness Index; Tramadol

2017
An overview of tramadol and its usage in pain management and future perspective.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 111

    Topics: Analgesics, Opioid; Animals; Chronic Pain; Drug Interactions; Forecasting; Humans; Pain Management; Tramadol

2019
Tramadol and acetaminophen combination for chronic non-cancer pain.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:16

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Chronic Pain; Drug Combinations; Humans; Tramadol; Treatment Outcome

2013
Combining opioid and adrenergic mechanisms for chronic pain.
    Postgraduate medicine, 2014, Volume: 126, Issue:4

    Topics: Analgesics, Opioid; Chronic Pain; Drug Combinations; Female; Humans; Middle Aged; Nociceptive Pain; Phenols; Selective Serotonin Reuptake Inhibitors; Tapentadol; Tramadol

2014
[Long-term opioid therapy in chronic noncancer pain. A systematic review and meta-analysis of efficacy, tolerability and safety in open-label extension trials with study duration of at least 26 weeks].
    Schmerz (Berlin, Germany), 2015, Volume: 29, Issue:1

    Topics: Analgesics, Opioid; Buprenorphine; Chronic Pain; Hydromorphone; Long-Term Care; Morphine; Oxycodone; Oxymorphone; Pain Measurement; Phenols; Randomized Controlled Trials as Topic; Tapentadol; Tramadol; Treatment Outcome

2015
"Weak" opioid analgesics. Codeine, dihydrocodeine and tramadol: no less risky than morphine.
    Prescrire international, 2016, Volume: 25, Issue:168

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Codeine; Dose-Response Relationship, Drug; Humans; Morphine; Respiration; Tramadol

2016
Trends in Tramadol: Pharmacology, Metabolism, and Misuse.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Pain; Analgesics, Opioid; Animals; Chronic Pain; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Compounding; Drug Interactions; Genotype; Humans; Opioid-Related Disorders; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Polymorphism, Genetic; Prescription Drug Misuse; Risk Factors; Tramadol

2017
[Mechanisms of action of therapeutic agents in the treatment of chronic pain in the spinal cord].
    Masui. The Japanese journal of anesthesiology, 2011, Volume: 60 Suppl

    Topics: Amines; Antidepressive Agents; Calcium Channel Blockers; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pregabalin; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Spinal Cord; Tramadol

2011
[Skin ulcer pain].
    Minerva medica, 2012, Volume: 103, Issue:6

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Drug Therapy, Combination; Humans; Neuralgia; Nociceptive Pain; Skin Ulcer; Tramadol

2012

Trials

13 trial(s) available for tramadol and Chronic Pain

ArticleYear
Efficacy and Safety of Tramadol Hydrochloride Twice-Daily Sustained-Release Bilayer Tablets with an Immediate-Release Component for Chronic Pain Associated with Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled, Treatment-Withdrawal Stud
    Clinical drug investigation, 2022, Volume: 42, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Chronic Pain; Delayed-Action Preparations; Double-Blind Method; Humans; Osteoarthritis, Knee; Tablets; Tramadol

2022
Association of
    Radiology and oncology, 2023, 03-01, Volume: 57, Issue:1

    Topics: Acetaminophen; Acute Pain; Breast Neoplasms; Chronic Pain; Female; Humans; MicroRNAs; Neuralgia; Receptors, Opioid, mu; Tramadol

2023
Reducing Opioid Use for Chronic Pain With a Group-Based Intervention: A Randomized Clinical Trial.
    JAMA, 2023, 05-23, Volume: 329, Issue:20

    Topics: Analgesics, Opioid; Chronic Pain; Female; Group Processes; Humans; Male; Middle Aged; Morphine; Opioid-Related Disorders; Self-Management; Tramadol

2023
Non-inferiority double-blind randomised controlled trial comparing gabapentin versus tramadol for the treatment of chronic neuropathic or mixed pain in children and adolescents: the GABA-1 trial-a study protocol.
    BMJ open, 2019, 02-20, Volume: 9, Issue:2

    Topics: Adolescent; Analgesics; Analgesics, Opioid; Child; Child, Preschool; Chronic Pain; Double-Blind Method; Female; Gabapentin; Humans; Infant; Male; Neuralgia; Tramadol

2019
Tramadol plus metamizole combined or not with anti-inflammatory drugs is clinically effective for moderate to severe chronic pain treatment in cancer patients.
    Veterinary anaesthesia and analgesia, 2013, Volume: 40, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Chronic Pain; Dipyrone; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Male; Neoplasms; Tramadol

2013
A randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of the extended-release tramadol hydrochloride/acetaminophen fixed-dose combination tablet for the treatment of chronic low back pain.
    Clinical therapeutics, 2013, Volume: 35, Issue:11

    Topics: Acetaminophen; Adult; Aged; Analgesics; Chronic Pain; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Low Back Pain; Male; Middle Aged; Pain Measurement; Tablets; Tramadol; Treatment Outcome

2013
Do analgesics improve functioning in patients with chronic low back pain? An explorative triple-blinded RCT.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2014, Volume: 23, Issue:4

    Topics: Acetaminophen; Adult; Analgesics; Chronic Pain; Disability Evaluation; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Humans; Low Back Pain; Male; Middle Aged; Pain Measurement; Recovery of Function; Self Report; Tramadol; Treatment Outcome

2014
[Conversion to tapentadol PR improves analgesia and quality of life in patients with severe and chronic pain despite using tramadol > 300 mg/d].
    Wiener klinische Wochenschrift, 2015, Volume: 127, Issue:11-12

    Topics: Aged; Analgesics, Opioid; Chronic Pain; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pain Measurement; Phenols; Quality of Life; Receptors, Opioid, mu; Tapentadol; Tramadol; Treatment Outcome

2015
Effect of postoperative analgesia on acute and persistent postherniotomy pain: a randomized study.
    Journal of clinical anesthesia, 2015, Volume: 27, Issue:8

    Topics: Acute Pain; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Female; Hernia, Inguinal; Herniorrhaphy; Humans; Ketorolac; Male; Middle Aged; Pain, Postoperative; Single-Blind Method; Time Factors; Tramadol

2015
Direct conversion from tramadol to tapentadol prolonged release for moderate to severe, chronic malignant tumour-related pain.
    European journal of pain (London, England), 2016, Volume: 20, Issue:9

    Topics: Aged; Analgesics, Opioid; Cancer Pain; Chronic Pain; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Phenols; Tapentadol; Tramadol; Treatment Outcome

2016
The effects of gabapentin on acute and chronic postoperative pain after coronary artery bypass graft surgery.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:5

    Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Chronic Disease; Chronic Pain; Coronary Artery Bypass; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Myocardial Revascularization; Pain Measurement; Pain, Postoperative; Prospective Studies; Sample Size; Sternotomy; Tramadol

2011
Eperisone versus tizanidine for treatment of chronic low back pain.
    Minerva medica, 2012, Volume: 103, Issue:3

    Topics: Analysis of Variance; Chronic Pain; Clonidine; Drug Therapy, Combination; Female; Humans; Italy; Low Back Pain; Male; Middle Aged; Muscle Contraction; Muscle Relaxants, Central; Pain Management; Pain Measurement; Propiophenones; Prospective Studies; Tramadol

2012
Efficacy and safety of flupirtine modified release for the management of moderate to severe chronic low back pain: results of SUPREME, a prospective randomized, double-blind, placebo- and active-controlled parallel-group phase IV study.
    Current medical research and opinion, 2012, Volume: 28, Issue:10

    Topics: Adolescent; Adult; Aged; Aminopyridines; Analgesics, Opioid; Chronic Pain; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Low Back Pain; Male; Middle Aged; Prospective Studies; Time Factors; Tramadol

2012

Other Studies

45 other study(ies) available for tramadol and Chronic Pain

ArticleYear
Opioid-Induced Esophageal Dysmotility (OIED) - A Case Report.
    Zeitschrift fur Gastroenterologie, 2023, Volume: 61, Issue:9

    Topics: Aged; Analgesics, Opioid; Chronic Pain; Esophageal Motility Disorders; Esophageal Spasm, Diffuse; Female; Humans; Tramadol

2023
Comparative Study of Opioid Initiation With Tramadol, Short-acting Hydrocodone, or Short-acting Oxycodone on Opioid-related Adverse Outcomes Among Chronic Noncancer Pain Patients.
    The Clinical journal of pain, 2023, Mar-01, Volume: 39, Issue:3

    Topics: Analgesics, Opioid; Chronic Pain; Humans; Hydrocodone; Opioid-Related Disorders; Oxycodone; Retrospective Studies; Tramadol

2023
Long-term deprescription in chronic pain and opioid use disorder patients: Pharmacogenetic and sex differences.
    Acta pharmaceutica (Zagreb, Croatia), 2023, Jun-01, Volume: 73, Issue:2

    Topics: Analgesics, Opioid; Chronic Pain; Cross-Sectional Studies; Cytochrome P-450 CYP2D6; Deprescriptions; Female; Humans; Male; Opioid-Related Disorders; Pharmacogenetics; Sex Characteristics; Tramadol

2023
Acute Pain in Perspective.
    The Journal of family practice, 2023, Volume: 72, Issue:6 Suppl

    Topics: Acute Pain; Analgesics, Opioid; Chronic Pain; Humans; Quality of Life; Tramadol

2023
Tramadol for chronic pain in adults: protocol for a systematic review with meta-analysis and trial sequential analysis of randomised clinical trials.
    Systematic reviews, 2023, 08-22, Volume: 12, Issue:1

    Topics: Adult; Cancer Pain; Chronic Pain; GRADE Approach; Humans; MEDLINE; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Systematic Reviews as Topic; Tramadol

2023
Dose rationale for gabapentin and tramadol in pediatric patients with chronic pain.
    Pharmacology research & perspectives, 2023, Volume: 11, Issue:5

    Topics: Adult; Analgesia; Child; Chronic Pain; Gabapentin; Humans; Infant; Prospective Studies; Tramadol

2023
Duplicated tramadol use in chronic low back pain: A nationwide cross-sectional study.
    Basic & clinical pharmacology & toxicology, 2020, Volume: 126, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Cross-Sectional Studies; Databases, Factual; Drug Prescriptions; Female; Humans; Low Back Pain; Male; Middle Aged; Practice Patterns, Physicians'; Republic of Korea; Tramadol

2020
Tramadol prescribed use in general and chronic noncancer pain: a nationwide register-based cohort study of all patients above 16 years.
    Scandinavian journal of pain, 2019, 12-18, Volume: 20, Issue:1

    Topics: Analgesics, Opioid; Chronic Pain; Cohort Studies; Databases, Factual; Denmark; Drug Prescriptions; Female; Humans; Inappropriate Prescribing; Longitudinal Studies; Male; Middle Aged; Opioid-Related Disorders; Sex Factors; Tramadol

2019
Characteristics and circumstances of heroin and pharmaceutical opioid overdose deaths: Comparison across opioids.
    Drug and alcohol dependence, 2019, 12-01, Volume: 205

    Topics: Adolescent; Adult; Analgesics, Opioid; Australia; Chronic Pain; Drug Overdose; Drug Prescriptions; Female; Fentanyl; Heroin; Humans; Male; Methadone; Middle Aged; Morphine; Naloxone; Opioid-Related Disorders; Tramadol; Young Adult

2019
Association of Tramadol Use With Risk of Hip Fracture.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2020, Volume: 35, Issue:4

    Topics: Analgesics, Opioid; Chronic Pain; Cohort Studies; Female; Humans; Risk Factors; Tramadol; United Kingdom

2020
CYP2D6 Basic Genotyping of Patients with Chronic Pain Receiving Tramadol or Codeine. A Study in a Greek Cohort.
    Pain medicine (Malden, Mass.), 2020, 11-01, Volume: 21, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Codeine; Cohort Studies; Cytochrome P-450 CYP2D6; Female; Genotype; Greece; Humans; Male; Middle Aged; Prospective Studies; Tramadol; Young Adult

2020
Factors affecting the effect of naldemedine for opioid-induced constipation: a single-institution, retrospective analysis.
    Die Pharmazie, 2021, 04-01, Volume: 76, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cholinergic Antagonists; Chronic Pain; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Induced Constipation; Retrospective Studies; Time Factors; Tramadol; Treatment Outcome; Young Adult

2021
[Monoaminergic opioids: which one should we choose?]
    Revue medicale suisse, 2021, Jun-23, Volume: 17, Issue:744

    Topics: Analgesics, Opioid; Chronic Pain; Constipation; Humans; Tapentadol; Tramadol

2021
Patterns of regional variation of opioid prescribing in primary care in England: a retrospective observational study.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2018, Volume: 68, Issue:668

    Topics: Analgesics, Opioid; Buprenorphine; Chronic Pain; Crime; Databases, Factual; Education; Employment; England; Health Status; Housing; Humans; Income; Methadone; Morphine; Oxycodone; Practice Patterns, Physicians'; Primary Health Care; Residence Characteristics; Retrospective Studies; Socioeconomic Factors; Tramadol

2018
The dilemma of repeat weak opioid prescriptions - experiences from swedish GPs.
    Scandinavian journal of primary health care, 2018, Volume: 36, Issue:2

    Topics: Adaptation, Psychological; Adult; Analgesics, Opioid; Attitude of Health Personnel; Chronic Pain; Codeine; Drug Prescriptions; Emotions; Ethics, Medical; Female; Focus Groups; General Practice; General Practitioners; Humans; Male; Middle Aged; Physician-Patient Relations; Practice Patterns, Physicians'; Qualitative Research; Stress, Psychological; Sweden; Tramadol

2018
Controlled-release in-situ gel forming formulation of tramadol containing chitosan-based pro-nanogels.
    International journal of biological macromolecules, 2018, Oct-15, Volume: 118, Issue:Pt B

    Topics: Chitosan; Chronic Pain; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Gels; Kinetics; Nanostructures; Tramadol

2018
Prescription opioid analgesic use in France: Trends and impact on morbidity-mortality.
    European journal of pain (London, England), 2019, Volume: 23, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Chronic Pain; Codeine; Databases, Factual; Dextropropoxyphene; Female; Fentanyl; France; Humans; Male; Middle Aged; Mortality; Opioid-Related Disorders; Opium; Oxycodone; Prevalence; Proportional Hazards Models; Tramadol

2019
Tramadol use in Norway: A register-based population study.
    Pharmacoepidemiology and drug safety, 2019, Volume: 28, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Drug Prescriptions; Drug Utilization Review; Female; Follow-Up Studies; Humans; Male; Middle Aged; Norway; Opioid-Related Disorders; Pain Management; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prospective Studies; Registries; Tramadol

2019
Health benefits of an adverse events reporting system for chronic pain patients using long-term opioids.
    Acta anaesthesiologica Scandinavica, 2019, Volume: 63, Issue:2

    Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Female; Fentanyl; Humans; Male; Middle Aged; Outpatients; Pain Management; Pharmacovigilance; Physicians; Retrospective Studies; Self Report; Tramadol

2019
Profiles of visuospatial memory dysfunction in opioid-exposed and dependent populations.
    Psychological medicine, 2019, Volume: 49, Issue:7

    Topics: Adult; Agnosia; Analgesics, Opioid; Chronic Pain; Codeine; Female; Heroin Dependence; Humans; Male; Memory Disorders; Mental Recall; Methadone; Neuropsychological Tests; Risk Factors; Tramadol; United Kingdom

2019
Influence of tramadol on functional recovery of acute spinal cord injury in rats.
    Acta cirurgica brasileira, 2018, Volume: 33, Issue:12

    Topics: Acute Disease; Analgesics, Opioid; Animals; Chronic Pain; Laminectomy; Male; Pain Measurement; Random Allocation; Rats, Wistar; Recovery of Function; Reproducibility of Results; Spinal Cord Injuries; Time Factors; Tramadol; Treatment Outcome

2018
Infographic. Tramadol: should it be banned in athletes while competing, particularly in road cycling?
    British journal of sports medicine, 2020, Volume: 54, Issue:2

    Topics: Acute Pain; Analgesics, Opioid; Bicycling; Chronic Pain; Competitive Behavior; Doping in Sports; Humans; Tramadol

2020
Medical Use of Long-term Extended-release Opioid Analgesics in Commercially Insured Adults in the United States.
    Pain medicine (Malden, Mass.), 2020, 04-01, Volume: 21, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Arthritis; Back Pain; Cancer Pain; Chronic Pain; Delayed-Action Preparations; Duration of Therapy; Female; Fentanyl; Humans; Insurance, Health; Male; Middle Aged; Morphine; Oxycodone; Tramadol; United States

2020
[Tramadol/acetaminophen combination tablets].
    Masui. The Japanese journal of anesthesiology, 2013, Volume: 62, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Pain; Drug Combinations; Humans; Middle Aged; Pain, Intractable; Tablets; Tramadol

2013
The therapeutic management of chronic pain in ambulatory care patients aged 65 and over in France: the S.AGES Cohort. Baseline data.
    The journal of nutrition, health & aging, 2013, Volume: 17, Issue:8

    Topics: Acetaminophen; Aged; Aged, 80 and over; Ambulatory Care; Analgesics; Back Pain; Chronic Pain; Dextropropoxyphene; Female; Humans; Male; Osteoarthritis; Pain Management; Prospective Studies; Severity of Illness Index; Tramadol

2013
The analgesic effect of tramadol in animal models of neuropathic pain and fibromyalgia.
    Neuroscience letters, 2014, Mar-06, Volume: 562

    Topics: Analgesics, Opioid; Animals; Chronic Pain; Disease Models, Animal; Fibromyalgia; Male; Neuralgia; Pain Measurement; Rats; Rats, Sprague-Dawley; Tramadol

2014
Pain management discussion forum: serious interaction among frequently used drugs for chronic pain.
    Journal of pain & palliative care pharmacotherapy, 2014, Volume: 28, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Chronic Pain; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Serotonin Syndrome; Thiophenes; Tramadol

2014
Transient serotonin syndrome caused by concurrent use of tramadol and selective serotonin reuptake inhibitor.
    The American journal of case reports, 2014, Dec-19, Volume: 15

    Topics: Adult; Analgesics, Opioid; Chronic Pain; Depressive Disorder, Major; Drug Interactions; Female; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol

2014
Tramadol and the risk of fracture in an elderly female population: a cost utility assessment with comparison to transdermal buprenorphine.
    The European journal of health economics : HEPAC : health economics in prevention and care, 2016, Volume: 17, Issue:2

    Topics: Aged; Aged, 80 and over; Buprenorphine; Chronic Pain; Cost-Benefit Analysis; Drug Costs; Female; Fractures, Bone; Health Care Costs; Humans; Models, Economic; Quality-Adjusted Life Years; Risk Factors; Tramadol; Transdermal Patch; United Kingdom

2016
Overall safety profile and effectiveness of tramadol hydrochloride/acetaminophen in patients with chronic noncancer pain in Japanese real-world practice.
    Current medical research and opinion, 2015, Volume: 31, Issue:11

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Pain; Female; Humans; Japan; Male; Middle Aged; Pain Measurement; Prospective Studies; Tablets; Tramadol; Treatment Outcome; Young Adult

2015
Coadministration of tramadol with aripiprazole and venlafaxine--The effect on spatial memory functions in male rats.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:2

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Chronic Pain; Depression; Disease Models, Animal; Male; Maze Learning; Memory Disorders; Rats; Rats, Wistar; Spatial Memory; Tramadol; Venlafaxine Hydrochloride

2016
Estimation of minimal clinically important change of the Japanese version of EQ-5D in patients with chronic noncancer pain: a retrospective research using real-world data.
    Health and quality of life outcomes, 2016, Mar-01, Volume: 14

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Female; Humans; Japan; Male; Middle Aged; Patients; Quality of Life; Regression Analysis; Retrospective Studies; Tramadol; Treatment Outcome

2016
Effect of Preoperative Inflammatory Status and Comorbidities on Pain Resolution and Persistent Postsurgical Pain after Inguinal Hernia Repair.
    Mediators of inflammation, 2016, Volume: 2016

    Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Comorbidity; Female; Hernia, Inguinal; Humans; Intraoperative Complications; Ketorolac; Longitudinal Studies; Male; Middle Aged; Pain Measurement; Tramadol

2016
Potential for Drug-Drug Interactions with Adjunctive Tramadol Use in Treatment of Obsessive-Compulsive Disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2016, Volume: 61, Issue:5

    Topics: Aged; Analgesics, Opioid; Chronic Pain; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Humans; Male; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Tramadol

2016
Incidence of tramadol shopping behavior in a retrospective cohort of chronic non-cancer pain patients in France.
    Pharmacoepidemiology and drug safety, 2016, Volume: 25, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Cohort Studies; Databases, Factual; Drug-Seeking Behavior; Female; France; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Physicians; Practice Patterns, Physicians'; Prescription Drug Misuse; Retrospective Studies; Risk Factors; Sex Factors; Tramadol

2016
Biomedicine: Move over, morphine.
    Nature, 2016, 07-14, Volume: 535, Issue:7611

    Topics: Acute Pain; Adult; Chronic Pain; Drug Tolerance; Early Medical Intervention; Humans; Male; Morphine; Morphine Derivatives; Neural Inhibition; Oligopeptides; Opioid-Related Disorders; Pain Management; Peptides, Cyclic; Phenols; Receptors, Opioid, mu; Spinal Cord Stimulation; Tapentadol; Tramadol; Young Adult

2016
Effect of Tramadol/Acetaminophen on Motivation in Patients with Chronic Low Back Pain.
    Pain research & management, 2016, Volume: 2016

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Apathy; Case-Control Studies; Catastrophization; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Disability Evaluation; Female; Humans; Low Back Pain; Male; Middle Aged; Motivation; Pain Measurement; Retrospective Studies; Tramadol; Treatment Outcome

2016
New Initiation of Long-Acting Opioids in Long-Stay Nursing Home Residents.
    Journal of the American Geriatrics Society, 2016, Volume: 64, Issue:9

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Chronic Pain; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Utilization; Female; Fentanyl; Homes for the Aged; Humans; Long-Term Care; Male; Morphine; Nursing Homes; Oxycodone; Oxymorphone; Practice Patterns, Physicians'; Rhode Island; Tramadol

2016
Tramadol-induced adrenal insufficiency.
    European journal of clinical pharmacology, 2011, Volume: 67, Issue:8

    Topics: Abdominal Pain; Adrenal Insufficiency; Adult; Analgesics, Opioid; Chronic Pain; Dizziness; Drug Monitoring; Female; Headache; Humans; Tramadol; Vision, Low; Vomiting; Young Adult

2011
Double-phase hydrogel for buccal delivery of tramadol.
    Drug development and industrial pharmacy, 2012, Volume: 38, Issue:4

    Topics: Administration, Buccal; Analgesics, Opioid; Animals; Biocompatible Materials; Biological Availability; Chickens; Chronic Pain; Delayed-Action Preparations; Drug Delivery Systems; Humans; Hydrogels; Male; Microspheres; Opioid-Related Disorders; Particle Size; Polyvinyl Alcohol; Rats; Rats, Wistar; Tramadol

2012
Canadian guideline for safe and effective use of opioids for chronic noncancer pain: clinical summary for family physicians. Part 1: general population.
    Canadian family physician Medecin de famille canadien, 2011, Volume: 57, Issue:11

    Topics: Analgesics, Opioid; Benzodiazepines; Canada; Chronic Pain; Codeine; Humans; Hydromorphone; Mass Screening; Opioid-Related Disorders; Oxycodone; Patient Education as Topic; Sleep Apnea Syndromes; Tramadol

2011
Bridging health technology assessment (HTA) with multicriteria decision analyses (MCDA): field testing of the EVIDEM framework for coverage decisions by a public payer in Canada.
    BMC health services research, 2011, Nov-30, Volume: 11

    Topics: Advisory Committees; Analgesics, Opioid; Canada; Chronic Pain; Decision Making, Organizational; Decision Support Techniques; Humans; Insurance Coverage; Insurance, Health; Public Sector; Reproducibility of Results; Technology Assessment, Biomedical; Tramadol

2011
Serotonin syndrome in a patient with chronic pain polypharmacy.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:8

    Topics: Adult; Amitriptyline; Anti-Allergic Agents; Antidepressive Agents; Carisoprodol; Cetirizine; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Muscle Relaxants, Central; Narcotics; Polypharmacy; Serotonin Syndrome; Thiophenes; Tramadol

2014
An open label trial of the effects and safety profile of extended-release tramadol in the management of chronic pain.
    Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2012, Volume: 50, Issue:3

    Topics: Aged; Analgesics, Opioid; Chronic Pain; Delayed-Action Preparations; Disease Management; Female; Humans; Male; Middle Aged; Tramadol

2012
Tramadol induced paradoxical hyperalgesia.
    Pain physician, 2013, Volume: 16, Issue:1

    Topics: Aged; Analgesics, Opioid; Chronic Pain; Female; Humans; Hyperalgesia; Male; Middle Aged; Tramadol

2013