Page last updated: 2024-08-23

tramadol and Chemical Dependence

tramadol has been researched along with Chemical Dependence in 73 studies

Research

Studies (73)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (4.11)	18.7374
1990's	7 (9.59)	18.2507
2000's	26 (35.62)	29.6817
2010's	23 (31.51)	24.3611
2020's	14 (19.18)	2.80

Authors

Authors	Studies
Ameen, N; Bassiony, MM; Mahdy, RS; Salah El-Deen, GM	1
Aly Zayed, M; Mohamed El-Seidy, A; Ragab Allam, A; Said Shalaby, A	1
Azab, SMS; Hayes, BD; Tawfik, H	1
Fouilhé, N; Fouque, C; Frauger, E; Jouanjus, E; Lapeyre-Mestre, M; Mallaret, M; Micallef, J; Roussin, A; Soeiro, T	1
Fairman, BJ; Rezaeiahari, M	1
Bamidele, R; Enya, JI; Feyisike Johnson, O; Hamzat, EO; Johnson, BS; Olanrewaju, I; Olanrewaju, JA; Osuoya, Q; Owolabi, JO; Udekwu, MO	1
Beshel, FN; Mkpe, ID; Nwangwa, JN; Ofuru, OS; Sam-Ekpe, VG; Stephen, GI; Udefa, AL	1
Ajayi, AI; Somefun, OD	1
Carroll, A; Rakov, J	1
Kamal, D; Mansour, H; Rayan, M; Shnoda, M	1
Abdeen, MS; El Nagar, ZM; Elrassas, HH; Elsayed, YA; Mohamed, AT	1
Butler, SF; Dailey-Govoni, T; Green, JL	1
Aizen, J; Faris, SF; Ham, SA; Richgels, J; Wackerbarth, JJ	1
Bebarta, VS; Borys, DJ; Maddry, JK; Ng, PC; Sessions, D	1
Amiri, S; Ataee, R; Jafari-Sabet, M	1
Ameline, A; Kintz, P; Raul, JS	1
Mullins, ME; Rengarajan, A	1
Han, P; Liu, H; Liu, L; Pu, C; Qian, S; Wei, Q; Yang, L	1
El Husseiny, RM; Ghaffar, HM; Mohamed, TM	1
Arbarello, P; Mannocchi, G; Napoleoni, F; Napoletano, S; Pantano, F; Santoni, M; Tittarelli, R	1
Bidel, Z; Carson, KV; Nazarzadeh, M	1
Liu, Z; Zhang, H	1
Bergman, U; Carvajal, A; Conforti, A; D'Incau, P; Gony, M; Heerdink, R; Lapeyre-Mestre, M; Macias, D; Van der Stichele, R	1
Crane, J; Randall, C	1
Kintz, P	1
Ferrari, A; Licata, M; Marchesi, F; Palazzoli, F; Rustichelli, C; Vandelli, D; Verri, P	1
Mastropietro, DJ; Muppalaneni, S; Omidian, H	1
Abdel-Hamid, IA; Andersson, KE; Anis, TH; Waldinger, MD	1
Palmer, NR	1
Guan, DW; Wang, HX; Wang, L; Wang, MB	1
Hanada, M; Kitahara, M; Kojima, K; Kuriyama, Y; Ohmura, A	1
Afshari, R; Tashakori, A	1
Akhgari, M; Bahmanabadi, L; Iravani, FS; Jokar, F	1
Arndt, T; Claussen, U; Güssregen, B; Schröfel, S; Stürzer, B; Werle, A; Wolf, G	1
Barber, J	1
Kim, MH; Park, EC; Park, H; Park, K	1
Farajidana, H; Hassanian-Moghaddam, H; Sanaei-Zadeh, H; Zamani, N	1
Babalonis, S; Lofwall, MR; Nuzzo, PA; Siegel, AJ; Walsh, SL	1
Azouma, A; Maiga, DD; Seyni, H; Sidikou, A	1
Maiga, DD; Moussa, AO; Seyni, H; Sidikou, A	1
Bruckmann, W; Friderichs, E; Tzschentke, TM	1
Campbell, ED; Dawson, KS; Knisely, JS; Schnoll, SH	1
Carr, GD	1
Arfken, CL; Cicero, TJ	1
Adams, EH; Cicero, TJ; Geller, A; Inciardi, JA; Muñoz, A; Schnoll, S; Senay, EC; Woody, GE	1
Robbins, L	1
Backmund, M; Hasemann, S; Soyka, M	1
Mackler, L; McDiarmid, T; Schneider, DM	1
McDiarmid, T; Patt, S	1
Zacny, JP	1
Jovanović-Cupić, V; Martinović, Z; Nesić, N	1
Adams, EH; Breiner, S; Cicero, TJ; Geller, A; Inciardi, JA; Schnoll, SH; Senay, EC; Woody, GE	1
Ahlner, J; Hägg, S; Jönsson, AK; Tjäderborn, M	1
Raffa, RB	1
Budd, K	1
Ehrenreich, H; Poser, W	1
Grond, S; Lehmann, KA; Radbruch, L	1
Miranda, HF; Pinardi, G	1
Adams, EH; Cicero, TJ; Geller, A; Inciardi, JA; Muñoz, A; Schnoll, SH; Senay, EC; Woody, GE	1
Aknine, X; Boissonnas, A; Varescon-Pousson, I	1
Desmeules, JA	1
Liberto, V; Reeves, RR	1
Nguyen, MH; Warnock, JK; Yates, WR	1
Beitz, J; Bonnel, RA; Brinker, A	1
Felgenhauer, F; Friderichs, E; Jongschaap, P; Osterloh, G	1
Aledter, A; Nickel, B	1
Barth, H; Flohé, L; Giertz, H; Richter, W	1

Reviews

9 review(s) available for tramadol and Chemical Dependence

Article	Year
Role of tramadol in premature ejaculation: a systematic review and meta-analysis. Urologia internationalis, 2013, Volume: 91, Issue:2 Topics: Analgesics, Opioid; Coitus; Ejaculation; Humans; Male; Patient Satisfaction; Premature Ejaculation; Randomized Controlled Trials as Topic; Sexual Dysfunction, Physiological; Substance-Related Disorders; Time Factors; Tramadol; Treatment Outcome	2013
Tramadol Abuse and Sexual Function. Sexual medicine reviews, 2016, Volume: 4, Issue:3 Topics: Humans; Male; Premature Ejaculation; Substance-Related Disorders; Tramadol	2016
[Tramadol intoxication and its toxicological effect]. Fa yi xue za zhi, 2008, Volume: 24, Issue:4 Topics: Analgesics, Opioid; Forensic Toxicology; Humans; Substance-Related Disorders; Tramadol	2008
[Convulsive crisis in Tramadol and caffeine abusers: about 8 cases and review of the literature]. The Pan African medical journal, 2012, Volume: 13 Topics: Adolescent; Adult; Analgesics, Opioid; Caffeine; Central Nervous System Stimulants; Humans; Retrospective Studies; Seizures; Substance-Related Disorders; Tramadol; Young Adult	2012
Postmarketing surveillance for drug abuse. Drug and alcohol dependence, 2003, Jun-05, Volume: 70, Issue:3 Suppl Topics: Adverse Drug Reaction Reporting Systems; Appetite Depressants; Cyclobutanes; Drug Approval; Humans; Narcotics; Product Surveillance, Postmarketing; Substance-Related Disorders; Surveys and Questionnaires; Tramadol	2003
Basic pharmacology relevant to drug abuse assessment: tramadol as example. Journal of clinical pharmacy and therapeutics, 2008, Volume: 33, Issue:2 Topics: Analgesics, Opioid; Animals; Brain; Cytochrome P-450 CYP2D6; Humans; Narcotics; Substance-Related Disorders; Tramadol	2008
Chronic pain--challenge and response. Drugs, 1994, Volume: 47 Suppl 1 Topics: Chronic Disease; Clinical Trials as Topic; Drug Interactions; Drug Tolerance; Gastrointestinal Motility; Humans; Pain; Substance-Related Disorders; Tramadol	1994
A risk-benefit assessment of tramadol in the management of pain. Drug safety, 1996, Volume: 15, Issue:1 Topics: Administration, Oral; Analgesics, Opioid; Animals; Central Nervous System; Digestive System; Hemodynamics; Humans; Injections, Intramuscular; Pain; Pain, Postoperative; Risk Assessment; Substance-Related Disorders; Tramadol	1996
The tramadol option. European journal of pain (London, England), 2000, Volume: 4 Suppl A Topics: Analgesics, Opioid; Drug Prescriptions; Humans; Incidence; Pain; Palliative Care; Severity of Illness Index; Substance-Related Disorders; Tramadol	2000

Trials

5 trial(s) available for tramadol and Chemical Dependence

Article	Year
Abuse liability and reinforcing efficacy of oral tramadol in humans. Drug and alcohol dependence, 2013, Apr-01, Volume: 129, Issue:1-2 Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Carbon Dioxide; Codeine; Cohort Studies; Double-Blind Method; Female; Flicker Fusion; Hemodynamics; Humans; Male; Middle Aged; Oxycodone; Oxygen; Psychomotor Performance; Pupil; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration; Substance-Related Disorders; Tramadol; Young Adult	2013
Tramadol post-marketing surveillance in health care professionals. Drug and alcohol dependence, 2002, Sep-01, Volume: 68, Issue:1 Topics: Adult; Analgesics, Opioid; Female; Health Personnel; Humans; Male; Middle Aged; Physicians; Product Surveillance, Postmarketing; Substance-Related Disorders; Tramadol; United States; United States Food and Drug Administration	2002
Profiling the subjective, psychomotor, and physiological effects of tramadol in recreational drug users. Drug and alcohol dependence, 2005, Nov-01, Volume: 80, Issue:2 Topics: Adult; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Humans; Illicit Drugs; Lorazepam; Male; Morphine; Narcotics; Norepinephrine; Psychomotor Performance; Receptors, Opioid, mu; Serotonin; Substance-Related Disorders; Tramadol	2005
A comparison of the abuse liability of tramadol, NSAIDs, and hydrocodone in patients with chronic pain. Journal of pain and symptom management, 2006, Volume: 31, Issue:5 Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Female; Humans; Hydrocodone; Male; Middle Aged; Pain; Prevalence; Substance-Related Disorders; Tramadol	2006
Clinical investigation on the development of dependence during oral therapy with tramadol. Arzneimittel-Forschung, 1985, Volume: 35, Issue:11 Topics: Administration, Oral; Adult; Aged; Cyclohexanols; Double-Blind Method; Drug Administration Schedule; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Naloxone; Pain; Precipitin Tests; Random Allocation; Substance Withdrawal Syndrome; Substance-Related Disorders; Tramadol	1985

Other Studies

59 other study(ies) available for tramadol and Chemical Dependence

Article	Year
Prevalence, correlates, and consequences of attention-deficit/hyperactivity disorder in a clinical sample of adults with tramadol use in Egypt. The American journal on addictions, 2022, Volume: 31, Issue:1 Topics: Adult; Attention Deficit Disorder with Hyperactivity; Cross-Sectional Studies; Egypt; Humans; Opioid-Related Disorders; Prevalence; Substance-Related Disorders; Tramadol	2022
Does tramadol dependence impair cognitive functions? International clinical psychopharmacology, 2022, 03-01, Volume: 37, Issue:2 Topics: Cognition; Cognitive Dysfunction; Executive Function; Humans; Neuropsychological Tests; Substance-Related Disorders; Tramadol	2022
Intoxication related to substances use in patients presenting to Ain Shams University Poisoning Treatment Center, Cairo, Egypt (2015-2019). Drug and alcohol review, 2022, Volume: 41, Issue:5 Topics: Adolescent; Cannabis; Child; Egypt; Humans; Male; Retrospective Studies; Substance-Related Disorders; Tramadol; Universities; Young Adult	2022
Increase of high-risk tramadol use and harmful consequences in France from 2013 to 2018: Evidence from the triangulation of addictovigilance data. British journal of clinical pharmacology, 2022, Volume: 88, Issue:8 Topics: Adult; Analgesics, Opioid; Cross-Sectional Studies; Female; France; Humans; Male; Pain; Substance-Related Disorders; Tramadol	2022
Impact of COVID-19 on the characteristics of opioid overdose deaths in Arkansas. The International journal on drug policy, 2022, Volume: 109 Topics: Analgesics, Opioid; Arkansas; COVID-19; Drug Overdose; Fentanyl; Humans; Methadone; Methamphetamine; Narcotics; Opiate Overdose; Pandemics; Substance-Related Disorders; Tramadol	2022
An assessment of drug and substance abuse prevalence: a cross-sectional study among undergraduates in selected southwestern universities in Nigeria. The Journal of international medical research, 2022, Volume: 50, Issue:10 Topics: Codeine; Cross-Sectional Studies; Female; Humans; Male; Nigeria; Prevalence; Students; Substance-Related Disorders; Surveys and Questionnaires; Tramadol; Universities	2022
Vitamin E administration does not ameliorate tramadol-associated impairment of testicular function in Wistar rats. Andrologia, 2020, Volume: 52, Issue:1 Topics: Administration, Oral; Animals; Disease Models, Animal; Ejaculation; Epididymis; Humans; Infertility, Male; Male; Nigeria; Oxidative Stress; Rats; Rats, Wistar; Sperm Count; Sperm Motility; Spermatozoa; Substance-Related Disorders; Testis; Tramadol; Vitamin E	2020
Recreational drug use among Nigerian university students: Prevalence, correlates and frequency of use. PloS one, 2020, Volume: 15, Issue:5 Topics: Adolescent; Adult; Amphetamine-Related Disorders; Codeine; Cross-Sectional Studies; Female; Humans; Illicit Drugs; Male; Marijuana Use; Nigeria; Prevalence; Risk Factors; Students; Substance-Related Disorders; Surveys and Questionnaires; Tramadol; Universities; Young Adult	2020
A case of tramadol-induced psychosis on a background of mixed substance use resulting in serious violence. The Australian and New Zealand journal of psychiatry, 2021, Volume: 55, Issue:8 Topics: Humans; Psychotic Disorders; Schizophrenic Psychology; Substance-Related Disorders; Tramadol; Violence	2021
Cannabis and tramadol addiction: Do they imply additive risk for acute myocardial infarction in adults younger than 45 years? Anatolian journal of cardiology, 2020, Volume: 24, Issue:5 Topics: Adult; Age Factors; Cannabis; Egypt; Female; Humans; Male; Middle Aged; Myocardial Infarction; Non-ST Elevated Myocardial Infarction; Risk Factors; Substance-Related Disorders; Tramadol; Young Adult	2020
Cognitive impairment in patients diagnosed with tramadol dependence compared to healthy controls. International clinical psychopharmacology, 2021, Volume: 36, Issue:1 Topics: Case-Control Studies; Cognitive Dysfunction; Humans; Substance-Related Disorders; Tramadol	2021
Real-World Data on Nonmedical Use of Tramadol from Patients Evaluated for Substance Abuse Treatment in the NAVIPPRO Addiction Severity Index-Multimedia Version (ASI-MV Drug safety, 2021, Volume: 44, Issue:2 Topics: Female; Humans; Male; Prescription Drug Misuse; Severity of Illness Index; Substance-Related Disorders; Tramadol; United States	2021
Persistent Opioid Usage After Urologic Intervention and the Impact of Tramadol. Urology, 2021, Volume: 157 Topics: Adult; Analgesics, Opioid; Case-Control Studies; Comorbidity; Databases, Factual; Drug Prescriptions; Female; Humans; Male; Middle Aged; Pain, Postoperative; Risk Factors; Substance-Related Disorders; Time Factors; Tramadol; United States; Urologic Surgical Procedures; Young Adult	2021
Using Pill Identification Calls to Poison Centers as a Marker of Drug Abuse at Three Texas Military Bases. Southern medical journal, 2017, Volume: 110, Issue:11 Topics: Analgesics, Opioid; Dextropropoxyphene; Humans; Hydrocodone; Military Facilities; Opioid-Related Disorders; Poison Control Centers; Retrospective Studies; Substance-Related Disorders; Tablets; Telephone; Texas; Tramadol	2017
Cross state-dependency of learning between tramadol and MK-801 in the mouse dorsal hippocampus: involvement of nitric oxide (NO) signaling pathway. Psychopharmacology, 2018, Volume: 235, Issue:7 Topics: Amnesia; Analgesics, Opioid; Animals; Arginine; CA1 Region, Hippocampal; Conditioning, Classical; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Learning; Male; Memory; Mice; Microinjections; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Substance-Related Disorders; Tramadol	2018
Disappearance of Tramadol and THC-COOH in Hair After Discontinuation of Abuse. Two Different Profiles. Journal of analytical toxicology, 2020, Jan-07, Volume: 44, Issue:1 Topics: Dronabinol; Hair; Humans; Illicit Drugs; Substance Abuse Detection; Substance-Related Disorders; Tramadol	2020
How often do false-positive phencyclidine urine screens occur with use of common medications? Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:6 Topics: Alprazolam; Carbazoles; Carvedilol; Clonazepam; Dextromethorphan; Diphenhydramine; Drug Interactions; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Humans; Phencyclidine; Propanolamines; Retrospective Studies; Substance-Related Disorders; Tramadol	2013
Effects of tramadol, clonazepam, and their combination on brain mitochondrial complexes. Toxicology and industrial health, 2015, Volume: 31, Issue:12 Topics: Analgesics, Opioid; Animals; Anticonvulsants; Brain; Clonazepam; Disease Models, Animal; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Male; Mitochondria; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Opioid-Related Disorders; Qualitative Research; Random Allocation; Rats; Substance-Related Disorders; Tramadol; Weight Loss	2015
Fatal self administration of tramadol and propofol: a case report. Journal of forensic and legal medicine, 2013, Volume: 20, Issue:6 Topics: Analgesics, Opioid; Drug Overdose; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Health Personnel; Heart Arrest; Humans; Hypnotics and Sedatives; Limit of Detection; Liver; Male; Middle Aged; Propofol; Respiratory Insufficiency; Self Administration; Substance-Related Disorders; Tramadol	2013
The association between tramadol hydrochloride misuse and other substances use in an adolescent population: Phase I of a prospective survey. Addictive behaviors, 2014, Volume: 39, Issue:1 Topics: Adolescent; Alcohol Drinking; Amphetamine-Related Disorders; Analgesics, Opioid; Female; Humans; Iran; Male; Marijuana Smoking; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Odds Ratio; Opioid-Related Disorders; Opium; Prescription Drug Misuse; Prevalence; Prospective Studies; Sex Distribution; Substance-Related Disorders; Surveys and Questionnaires; Tramadol	2014
The investigation of tramadol dependence with no history of substance abuse: a cross-sectional survey of spontaneously reported cases in Guangzhou City, China. BioMed research international, 2013, Volume: 2013 Topics: Analgesics, Opioid; China; Cross-Sectional Studies; Heroin; Humans; Male; Methamphetamine; Substance-Related Disorders; Tramadol; Young Adult	2013
A European community pharmacy-based survey to investigate patterns of prescription fraud through identification of falsified prescriptions. European addiction research, 2014, Volume: 20, Issue:4 Topics: Analgesics, Opioid; Belgium; Benzodiazepines; Buprenorphine; Central Nervous System Stimulants; Cross-Sectional Studies; Drug Prescriptions; Europe; France; Fraud; Humans; Italy; Methylphenidate; Morphine; Netherlands; Pharmacies; Spain; Substance-Related Disorders; Sweden; Tramadol	2014
Tramadol deaths in Northern Ireland: a review of cases from 1996 to 2012. Journal of forensic and legal medicine, 2014, Volume: 23 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Depression; Drug Overdose; Female; Humans; Male; Middle Aged; Northern Ireland; Opioid-Related Disorders; Prescription Drug Diversion; Substance-Related Disorders; Tramadol; Young Adult	2014
Contribution of in utero drug exposure when interpreting hair results in young children. Forensic science international, 2015, Volume: 249 Topics: Amitriptyline; Bromazepam; Cannabinoids; Diazepam; Diphenhydramine; Female; Forensic Toxicology; Hair; Heroin; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Methadone; Narcotics; Pregnancy; Substance-Related Disorders; Tramadol	2015
Tramadol chronic abuse: an evidence from hair analysis by LC tandem MS. Journal of pharmaceutical and biomedical analysis, 2015, Volume: 102 Topics: Adult; Analgesics, Opioid; Chromatography, Liquid; Female; Hair; Humans; Male; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry; Tramadol; Young Adult	2015
Deterred drug abuse using superabsorbent polymers. Expert opinion on drug delivery, 2016, Volume: 13, Issue:11 Topics: Chemistry, Pharmaceutical; Drug Liberation; Kinetics; Polyethylene Glycols; Polymers; Substance-Related Disorders; Tablets; Tramadol; Water	2016
Tramadol for premature ejaculation. The journal of sexual medicine, 2009, Volume: 6, Issue:1 Topics: Analgesics, Opioid; Ejaculation; Humans; Male; Sexual Dysfunction, Physiological; Substance-Related Disorders; Tramadol	2009
[Effectiveness of oral tramadol hydrochloride for chronic non-malignant pain]. Masui. The Japanese journal of anesthesiology, 2009, Volume: 58, Issue:8 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Female; Humans; Male; Middle Aged; Pain; Substance-Related Disorders; Tramadol; Treatment Outcome; Young Adult	2009
Tramadol overdose as a cause of serotonin syndrome: a case series. Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:4 Topics: Adult; Demography; Drug Overdose; Female; Humans; Male; Prospective Studies; Seizures; Serotonin Syndrome; Substance-Related Disorders; Tramadol	2010
Current trends in tramadol-related fatalities, Tehran, Iran 2005-2008. Substance use & misuse, 2010, Volume: 45, Issue:13 Topics: Adolescent; Adult; Analgesics, Opioid; Autopsy; Child; Drug Interactions; Female; Forensic Toxicology; Humans; Iran; Male; Mortality; Substance-Related Disorders; Tramadol; Young Adult	2010
Kratom alkaloids and O-desmethyltramadol in urine of a "Krypton" herbal mixture consumer. Forensic science international, 2011, May-20, Volume: 208, Issue:1-3 Topics: Adult; Alkaloids; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Mitragyna; Plant Extracts; Plant Leaves; Secologanin Tryptamine Alkaloids; Substance Abuse Detection; Substance-Related Disorders; Tramadol	2011
Examining the use of tramadol hydrochloride as an antidepressant. Experimental and clinical psychopharmacology, 2011, Volume: 19, Issue:2 Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Drug Tolerance; Humans; Mice; Rats; Respiration; Seizures; Sleep; Substance Withdrawal Syndrome; Substance-Related Disorders; Tramadol	2011
Attitude and knowledge of physicians about cancer pain management: young doctors of South Korea in their early career. Japanese journal of clinical oncology, 2011, Volume: 41, Issue:6 Topics: Adrenal Cortex Hormones; Adult; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Attitude of Health Personnel; Benzodiazepines; Codeine; Drug Prescriptions; Drug Therapy, Combination; Drug Tolerance; Female; Fentanyl; Health Knowledge, Attitudes, Practice; Humans; Male; Medicine; Meperidine; Neoplasms; Pain; Pain Measurement; Physicians; Practice Patterns, Physicians'; Republic of Korea; Research Design; Self Concept; Substance-Related Disorders; Surveys and Questionnaires; Tramadol	2011
Tramadol-induced seizures and trauma. European review for medical and pharmacological sciences, 2012, Volume: 16 Suppl 1 Topics: Adolescent; Adult; Analgesics, Opioid; Child; Child, Preschool; Drug Overdose; Female; Humans; Male; Middle Aged; Retrospective Studies; Seizures; Substance-Related Disorders; Suicide, Attempted; Tramadol; Wounds and Injuries; Young Adult	2012
[Tramadol misuse by adolescents and young adults living on the streets]. The Pan African medical journal, 2012, Volume: 13 Topics: Adolescent; Adult; Age Factors; Analgesics, Opioid; Female; Homeless Youth; Humans; Illicit Drugs; Male; Niger; Prescription Drug Misuse; Social Alienation; Substance-Related Disorders; Tramadol; Young Adult	2012
Lack of sensitization during place conditioning in rats is consistent with the low abuse potential of tramadol. Neuroscience letters, 2002, Aug-23, Volume: 329, Issue:1 Topics: Animals; Behavior, Animal; Conditioning, Psychological; Male; Meptazinol; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Substance-Related Disorders; Tramadol	2002
A recovering physician being monitored by the Mississippi Recovering Physicians Program and prescribed Ultram. Journal of the Mississippi State Medical Association, 2002, Volume: 43, Issue:12 Topics: Analgesics, Opioid; Contraindications; Humans; Mississippi; Physician Impairment; Substance-Related Disorders; Tramadol	2002
Withdrawal syndrome and dependence: tramadol too. Prescrire international, 2003, Volume: 12, Issue:65 Topics: Analgesics, Opioid; Humans; Substance Withdrawal Syndrome; Substance-Related Disorders; Tramadol	2003
An independent assessment of MEDWatch reporting for abuse/dependence and withdrawal from Ultram (tramadol hydrochloride). Drug and alcohol dependence, 2003, Nov-24, Volume: 72, Issue:2 Topics: Analgesics, Opioid; Diagnostic and Statistical Manual of Mental Disorders; Electronic Data Processing; Humans; Liability, Legal; Mandatory Reporting; Public Health; Substance Withdrawal Syndrome; Substance-Related Disorders; Tramadol; United States; United States Food and Drug Administration; World Health Organization	2003
Tramadol for tension-type headache. Headache, 2004, Volume: 44, Issue:2 Topics: Analgesics, Opioid; Humans; Retrospective Studies; Substance-Related Disorders; Tension-Type Headache; Tramadol	2004
Tramadol use and dependence in chronic noncancer pain patients. Pharmacopsychiatry, 2004, Volume: 37, Issue:4 Topics: Analgesics, Opioid; Chronic Disease; Female; Humans; Male; Pain; Substance-Related Disorders; Tramadol	2004
Clinical inquiries. What is the addiction risk associated with tramadol? The Journal of family practice, 2005, Volume: 54, Issue:1 Topics: Evidence-Based Medicine; Humans; Narcotics; Practice Guidelines as Topic; Risk Factors; Substance-Related Disorders; Tramadol	2005
Tramadol addiction. The Journal of family practice, 2005, Volume: 54, Issue:4 Topics: Analgesics, Opioid; Humans; Risk Assessment; Substance-Related Disorders; Tramadol	2005
Seizures associated with intoxication and abuse of tramadol. Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:2 Topics: Adolescent; Adult; Drug Synergism; Electroencephalography; Female; Humans; Male; Narcotics; Prospective Studies; Seizures; Substance-Related Disorders; Tramadol	2006
Fatal unintentional intoxications with tramadol during 1995-2005. Forensic science international, 2007, Dec-20, Volume: 173, Issue:2-3 Topics: Accidents; Adolescent; Adult; Aged; Analgesics, Opioid; Central Nervous System Depressants; Ethanol; Female; Forensic Toxicology; Humans; Male; Middle Aged; Substance-Related Disorders; Sweden; Tramadol	2007
WHO Expert Committee on Drug Dependence. World Health Organization technical report series, 2006, Issue:942 Topics: 4-Butyrolactone; Advisory Committees; Azabicyclo Compounds; Buprenorphine; Butorphanol; Catha; Dronabinol; Drug and Narcotic Control; Drug Evaluation; Health Services Accessibility; Humans; Hydroxybutyrates; Ketamine; Piperazines; Psychotropic Drugs; Substance-Related Disorders; Thebaine; Tramadol; World Health Organization	2006
Dependence on tramadol. The Clinical investigator, 1993, Volume: 72, Issue:1 Topics: Adult; Drug Tolerance; Euphoria; Female; Humans; Naltrexone; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Tramadol	1993
[Drug administration. Notes from the Adverse Drug Reaction Board. Halogenated anasthetics can develop carbon monoxide in reaction with dry absorbent calcium]. Sygeplejersken, 1997, Apr-11, Volume: 97, Issue:15 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Inhalation; Calcium; Carbon Monoxide; Female; Humans; Hydrocarbons, Halogenated; Male; Middle Aged; Substance-Related Disorders; Tramadol	1997
Antinociception, tolerance, and physical dependence comparison between morphine and tramadol. Pharmacology, biochemistry, and behavior, 1998, Volume: 61, Issue:4 Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Linear Models; Logistic Models; Male; Mice; Morphine; Morphine Dependence; Receptors, Opioid; Substance-Related Disorders; Tramadol	1998
Tramadol: new preparation. Capsules: central analgesic; step 2 on the WHO scale. Prescrire international, 1998, Volume: 7, Issue:33 Topics: Acetaminophen; Aged; Analgesics, Opioid; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Double-Blind Method; France; Humans; Meta-Analysis as Topic; Morphine; Pain; Patient Compliance; Substance-Related Disorders; Tramadol; Treatment Outcome; World Health Organization	1998
A postmarketing surveillance program to monitor Ultram (tramadol hydrochloride) abuse in the United States. Drug and alcohol dependence, 1999, Nov-01, Volume: 57, Issue:1 Topics: Analgesics, Opioid; Drug Prescriptions; Humans; Product Surveillance, Postmarketing; Risk Assessment; Substance-Related Disorders; Tramadol; United States	1999
Drugs for pain. The Medical letter on drugs and therapeutics, 2000, Aug-21, Volume: 42, Issue:1085 Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Aspirin; Asthma; Buprenorphine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Humans; Injections; Isoenzymes; Ketorolac; Membrane Proteins; Narcotic Antagonists; Pain; Prostaglandin-Endoperoxide Synthases; Substance-Related Disorders; Tramadol	2000
[Tramadol dependence in a previous heroin addict]. Annales de medecine interne, 2000, Volume: 151 Suppl B Topics: Adult; Alcoholism; Analgesics, Opioid; Antipsychotic Agents; Follow-Up Studies; Heroin Dependence; Humans; Male; Substance Abuse, Intravenous; Substance-Related Disorders; Tiapamil Hydrochloride; Time Factors; Toothache; Tramadol	2000
Abuse of combinations of carisoprodol and tramadol. Southern medical journal, 2001, Volume: 94, Issue:5 Topics: Adult; Analgesics, Opioid; Carisoprodol; Drug Interactions; Female; Humans; Male; Muscle Relaxants, Central; Substance-Related Disorders; Tramadol	2001
Tramadol dependence with no history of substance abuse. The American journal of psychiatry, 2001, Volume: 158, Issue:6 Topics: Adult; Analgesics, Opioid; Carpal Tunnel Syndrome; Female; Humans; Pain; Substance-Related Disorders; Tramadol	2001
WHO Expert Committee on Drug Dependence. Thirty-second report. World Health Organization technical report series, 2001, Volume: 903 Topics: Amphetamines; Buprenorphine; Carisoprodol; Diazepam; Dibenzocycloheptenes; Diethylpropion; Dronabinol; Drug and Narcotic Control; Guidelines as Topic; Humans; Hydroxybutyrates; Narcotics; Papaver; Pentazocine; Psychotropic Drugs; Pyridines; Substance-Related Disorders; Tramadol; World Health Organization; Zolpidem	2001
Abuse, dependence, or withdrawal associated with tramadol. The American journal of psychiatry, 2002, Volume: 159, Issue:5 Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Humans; Substance Withdrawal Syndrome; Substance-Related Disorders; Tramadol; United States; United States Food and Drug Administration	2002
[Pharmacological studies on analgesia, dependence on and tolerance of tramadol, a potent analgetic drug (author's transl)]. Arzneimittel-Forschung, 1978, Volume: 28, Issue:1a Topics: Administration, Oral; Analgesics; Animals; Antitussive Agents; Cats; Cyclohexanols; Drug Interactions; Drug Tolerance; Female; Guinea Pigs; Haplorhini; Humans; In Vitro Techniques; Injections, Intraperitoneal; Male; Mice; Morphine; Muscle Contraction; Rabbits; Rats; Substance-Related Disorders; Tramadol	1978
Comparative physical dependence studies in rats with flupirtine and opiate receptor stimulating analgesics. Postgraduate medical journal, 1987, Volume: 63 Suppl 3 Topics: Aminopyridines; Analgesics; Animals; Body Weight; Buprenorphine; Codeine; Female; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance-Related Disorders; Tramadol	1987