tramadol has been researched along with Allodynia in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (3.77) | 18.2507 |
| 2000's | 17 (32.08) | 29.6817 |
| 2010's | 30 (56.60) | 24.3611 |
| 2020's | 4 (7.55) | 2.80 |
| Authors | Studies |
|---|---|
| López-Ortíz, M; Navarrete, A; Osuna-Martínez, U; Quiñonez-Bastidas, GN; Reda-Licea, AL; Regla, I | 1 |
| Arai, N; Fujita, A; Hanawa, T; Kawano, Y; Suzuki, Y; Takahashi, Y; Yoshizawa, K | 1 |
| Fu, F; Li, T; Liu, R; Wang, L; Wang, T; Zhai, R; Zhang, L | 1 |
| Costa, GL; Interlandi, C; Leonardi, F; Spadola, F | 1 |
| Battaglia, G; Bernabucci, M; Bruno, V; Cannella, M; Gradini, R; Imbriglio, T; Mascio, G; Nicoletti, F; Notartomaso, S; Scarselli, P; Zappulla, C | 1 |
| Corona-Ramos, JN; Déciga-Campos, M; García-López, P; Jaramillo-Morales, OA; López-Muñoz, FJ; Martínez-Racine, I; Medina, LA; Romero-Piña, M | 1 |
| Cañizares, FJ; Cobos, EJ; Entrena, JM; Fernández-Segura, E; Montilla-García, Á; Perazzoli, G; Portillo-Salido, E; Tejada, MÁ | 1 |
| Duff, EP; Hoggart, B; Huggins, JP; Massat, N; Pauer, L; Rogers, P; Tracey, I; Vennart, W; Wanigasekera, V; Wartolowska, K; Whitlock, M | 1 |
| Abdalla, HB; Clemente-Napimoga, JT; Gill, HS; Jain, AK; Napimoga, MH | 1 |
| Fujimoto, Y; Funao, T; Mori, T; Nishikawa, K; Suehiro, K; Yamada, T | 1 |
| Affaitati, G; Costantini, R; Fabrizio, A; Giamberardino, MA; Lapenna, D; Lopopolo, M; Massimini, F | 1 |
| Liu, R; Mei, XP; Wang, H; Wang, W; Wu, D; Xie, C; Xu, LX; Zhang, H; Zhang, J | 1 |
| Ho, I; Kotani, J; Mei, XP; Sakuma, Y; Wu, D; Xie, C; Xu, LX | 1 |
| Arizpe, HM; Clifford, JL; Fowler, M; Garza, TH; Loyd, DR; Novak, J; Petz, LN; Slater, TM | 1 |
| Asakura, K; Isami, K; Kaneko, S; Maeda, S; Nakagawa, T; Sakakiyama, M; Shirakawa, H; So, K | 1 |
| Castagné, V; Le Cudennec, C | 1 |
| Nonaka, T; Shinozaki, T; Yamada, T; Yamamoto, T | 1 |
| Abreu, M; Aguado, D; Benito, J; García-Fernández, J; Gómez de Segura, IA | 1 |
| Egashira, N; Higuchi, H; Kaname, T; Kawashiri, T; Shirahama, M; Tsutsumi, K; Ushio, S; Yamamoto, S | 1 |
| Egashira, N; Higuchi, H; Kawashiri, T; Ushio, S; Yamamoto, S | 1 |
| Harada, S; Kageyama, E; Matsuura, W; Tokuyama, S | 1 |
| Puig, MM; Romero, A; Romero-Alejo, E | 1 |
| Ballet, S; Chevillard, L; Guillemyn, K; Lagard, C; Laplanche, JL; Mégarbane, B; Risède, P; Spetea, M | 1 |
| Kim, SH; Mun, H; Park, KU; Song, J | 1 |
| Altis, K; Angioni, C; Geisslinger, G; Kuczka, K; Lötsch, J; Schmidt, H; Schmidtko, A; Tegeder, I | 1 |
| Obara, I; Przewlocka, B; Wordliczek, J; Wrzosek, A | 1 |
| Akgül, O; Aypar, U; Dogrul, A; Kozak, O; Kurt, E; Sahin, A; Seyrek, M; Sizlan, A; Yanarates, O; Yildirim, V | 1 |
| Granmo, M; Jensen, T; Schouenborg, J | 1 |
| Felt, SA; Howard, AM; Jampachaisri, K; Long, CT; McKeon, GP; Pacharinsak, C; Yeomans, DC | 1 |
| Li, ST; Liu, YT; Qiu, YM | 1 |
| Alvarez, P; Brun, A; Constandil, L; Correa, A; Hernández, A; Labertrandie, A; Lopez, J; Pelissier, T | 1 |
| Gustorff, B; Margeta, K; Ortner, CM; Schulz, M; Steiner, I | 1 |
| Akarsu, M; Otelcioğlu, S; Reisli, R; Tuncer, S | 1 |
| Kimura, M; Obata, H; Saito, S | 1 |
| Ahmed, RS; Banerjee, BD; Bhattacharya, SN; Dhakate, G; Jain, S; Mediratta, PK; Nasare, N; Saxena, AK | 1 |
| Chen, L; Li, YQ; Mei, XP; Wang, LY; Wang, W; Wu, D; Xu, LX; Zhang, H; Zhang, T | 1 |
| Cho, SY; Choi, JI; Kim, WM; Lee, HG; Lee, SH; Yoon, MH | 1 |
| Dost, R; Rostock, A; Rundfeldt, C | 1 |
| Kulkarni, SK; Patil, CS; Singh, VP | 1 |
| Li, Y; Luo, YL; Xiao, SS; Yu, C; Zhang, Q | 1 |
| Ide, S; Ikeda, K; Ishihara, K; Minami, M; Sora, I; Uhl, GR | 1 |
| Hama, A; Sagen, J | 1 |
| Christoph, T; Kögel, B; Schug, SA; Strassburger, W | 1 |
| Bianchi, M; Ferrario, P; Franchi, S; Martucci, C; Sacerdote, P | 1 |
| Fick, LG; Loram, LC; Mitchell, D; Skosana, M | 1 |
| Kamerman, P; Koller, A; Loram, L | 1 |
| Apaydin, S; Guneli, E; Karabay Yavasoglu, NU; Uyar, M | 1 |
| Onal, A; Parlar, A; Ulker, S | 1 |
| Bianchi, M; Panerai, AE | 1 |
| Andersen, G; Brøsen, K; Jensen, TS; Madsen, C; Sindrup, SH; Smith, T | 1 |
| Tsai, YC; Won, SJ | 1 |
| Coppe, MC; Gillardin, JM; Girard, P; Pansart, Y | 1 |
| Affaitati, G; De Laurentis, S; Giamberardino, MA; Lapenna, D; Lerza, R; Vecchiet, L | 1 |
6 trial(s) available for tramadol and Allodynia
| Article | Year |
|---|---|
Disambiguating pharmacological mechanisms from placebo in neuropathic pain using functional neuroimaging.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Female; Functional Neuroimaging; Humans; Hyperalgesia; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Net; Neuralgia; Pain Measurement; Pregabalin; Tramadol; Treatment Outcome; Wounds and Injuries; Young Adult | 2018 |
Analgesic efficacy of tramadol, pregabalin and ibuprofen in menthol-evoked cold hyperalgesia.
Topics: Adult; Analgesics; Analysis of Variance; Area Under Curve; Case-Control Studies; Cold Temperature; Cross-Over Studies; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Ibuprofen; Male; Menthol; Pain Measurement; Pain Threshold; Physical Stimulation; Pregabalin; Time Factors; Tramadol | 2009 |
Dose response of tramadol and its combination with paracetamol in UVB induced hyperalgesia.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cold Temperature; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Hyperalgesia; Male; Pain Measurement; Pain Threshold; Physical Stimulation; Regional Blood Flow; Sample Size; Skin; Sunburn; Tramadol; Ultraviolet Rays; Young Adult | 2012 |
[The role of magnesium in preventing postoperative hyperalgesia].
Topics: Administration, Intravenous; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Female; Humans; Hyperalgesia; Hysterectomy; Intraoperative Period; Magnesium; Middle Aged; Morphine; Pain, Postoperative; Piperidines; Preanesthetic Medication; Remifentanil; Tramadol | 2012 |
A randomized, prospective study of efficacy and safety of oral tramadol in the management of post-herpetic neuralgia in patients from north India.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Herpesviridae Infections; Humans; Hyperalgesia; India; Male; Middle Aged; Neuralgia; Pain Measurement; Pain Threshold; Prospective Studies; Quality of Life; Single-Blind Method; Surveys and Questionnaires; Time Factors; Tramadol; Treatment Outcome; Young Adult | 2013 |
Tramadol relieves pain and allodynia in polyneuropathy: a randomised, double-blind, controlled trial.
Topics: Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Female; Humans; Hyperalgesia; Male; Middle Aged; Pain; Pain Measurement; Polyneuropathies; Statistics, Nonparametric; Touch; Tramadol | 1999 |
47 other study(ies) available for tramadol and Allodynia
| Article | Year |
|---|---|
Synergistic action between a synthetic cannabinoid compound and tramadol in neuropathic pain rats.
Topics: Analgesics, Opioid; Animals; Cannabinoids; Cisplatin; Hyperalgesia; Neuralgia; Rats; Tramadol | 2022 |
Synergistic Antinociceptive Activity of Tramadol/Acetaminophen Combination Mediated by μ-Opioid Receptors.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Drug Synergism; Drug Therapy, Combination; Gastrointestinal Transit; Hyperalgesia; Inflammation; Male; Mice, Inbred C57BL; Neuralgia; Receptors, Opioid, mu; Tramadol | 2020 |
Antinociceptive effects of rotigotine-loaded microspheres and its synergistic interactions with analgesics in inflammatory pain in rats.
Topics: Acetaminophen; Analgesics; Animals; Behavior, Animal; Carrageenan; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Drug Synergism; Drug Therapy, Combination; Hyperalgesia; Locomotion; Male; Microspheres; Nociceptive Pain; Open Field Test; Pain Threshold; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thiophenes; Tramadol | 2021 |
Evaluation of the paw withdrawal latency for the comparison between tramadol and butorphanol administered locally, in the plantar surface of rat, preliminary study.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Butorphanol; Heart Rate; Humans; Hyperalgesia; Pain; Rats; Rats, Wistar; Respiratory Rate; Tramadol | 2021 |
Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain.
Topics: Acetylcarnitine; Amitriptyline; Analgesics; Animals; Chronic Disease; Disease Models, Animal; Epigenesis, Genetic; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Neuralgia; Pain Management; Pregabalin; Receptors, Metabotropic Glutamate; Time Factors; Tramadol | 2017 |
The Effect of Gabapentin and Tramadol in Cancer Pain Induced by Glioma Cell in Rat Femur.
Topics: Amines; Analgesics; Animals; Bone Neoplasms; Brain Neoplasms; Cancer Pain; Cell Line, Tumor; Cell Survival; Cyclohexanecarboxylic Acids; Femur; Gabapentin; gamma-Aminobutyric Acid; Glioblastoma; Hyperalgesia; Neoplasm Transplantation; Pain Measurement; Rats; Tramadol; Treatment Outcome | 2017 |
Grip strength in mice with joint inflammation: A rheumatology function test sensitive to pain and analgesia.
Topics: Acetaminophen; Analgesics; Animals; Arthritis; Celecoxib; Disease Models, Animal; Diterpenes; Female; Freund's Adjuvant; Hand Strength; Hyperalgesia; Ibuprofen; Inflammation; Muscle Strength; Nociceptors; Oxycodone; Pain Measurement; Rheumatic Diseases; Ruthenium Red; Tarsus, Animal; Touch; Tramadol; TRPV Cation Channels | 2017 |
Microneedles Coated with Tramadol Exhibit Antinociceptive Effect in a Rat Model of Temporomandibular Hypernociception.
Topics: Analgesics, Opioid; Animals; Cytokines; Drug Delivery Systems; Formaldehyde; Hyperalgesia; Injections, Intra-Articular; Injections, Intralesional; Male; Needles; Rats; Rats, Wistar; Temporomandibular Joint; Temporomandibular Joint Dysfunction Syndrome; Tramadol | 2019 |
Relationship between noradrenaline release in the locus coeruleus and antiallodynic efficacy of analgesics in rats with painful diabetic neuropathy.
Topics: Adrenergic Neurons; Analgesics; Animals; Clomipramine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Female; Hyperalgesia; Locus Coeruleus; Morphine; Naloxone; Norepinephrine; Rats; Rats, Sprague-Dawley; Tramadol | 2013 |
Effects of tramadol on viscero-visceral hyperalgesia in a rat model of endometriosis plus ureteral calculosis.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Endometriosis; Female; Hyperalgesia; Rats, Sprague-Dawley; Tramadol; Ureteral Calculi; Visceral Pain | 2014 |
Tramadol and propentofylline coadministration exerted synergistic effects on rat spinal nerve ligation-induced neuropathic pain.
Topics: Analgesics, Opioid; Animals; Drug Combinations; Drug Synergism; Hyperalgesia; Injections, Spinal; Interleukin-1beta; Ligation; Male; Motor Activity; Neuralgia; Posterior Horn Cells; Rats; Spinal Nerves; Tramadol; Xanthines | 2013 |
Depressing interleukin-1β contributed to the synergistic effects of tramadol and minocycline on spinal nerve ligation-induced neuropathic pain.
Topics: Analgesics; Animals; Antibodies; Drug Combinations; Hyperalgesia; Imidazoles; Interleukin-1beta; Ligation; Male; Microglia; Minocycline; Neuralgia; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Posterior Horn Cells; Pyridines; Rats, Sprague-Dawley; Rotarod Performance Test; Signal Transduction; Spinal Nerves; Tramadol | 2014 |
A rat model of full thickness thermal injury characterized by thermal hyperalgesia, mechanical allodynia, pronociceptive peptide release and tramadol analgesia.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Burns; Calcitonin Gene-Related Peptide; Disease Models, Animal; Hyperalgesia; Male; Morphine; Nociception; Nociceptive Pain; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Tramadol | 2014 |
Preventive and alleviative effect of tramadol on neuropathic pain in rats: roles of α₂-adrenoceptors and spinal astrocytes.
Topics: Analgesics, Opioid; Animals; Astrocytes; Disease Models, Animal; Dopamine beta-Hydroxylase; Hyperalgesia; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Spinal Cord; Tramadol | 2014 |
Face-to-face comparison of the predictive validity of two models of neuropathic pain in the rat: analgesic activity of pregabalin, tramadol and duloxetine.
Topics: Analgesics; Animals; Cold Temperature; Disease Models, Animal; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Male; Neuralgia; Physical Stimulation; Pregabalin; Rats, Wistar; Sciatic Nerve; Thiophenes; Tramadol | 2014 |
Acetaminophen and non-steroidal anti-inflammatory drugs interact with morphine and tramadol analgesia for the treatment of neuropathic pain in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Hyperalgesia; Male; Morphine; Neuralgia; Rats; Rats, Sprague-Dawley; Tramadol | 2015 |
Tramadol-induced hyperalgesia and its prevention by ketamine in rats: A randomised experimental study.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Hyperalgesia; Ketamine; Male; Methyl Ethers; Pulmonary Alveoli; Random Allocation; Rats; Rats, Wistar; Sevoflurane; Time Factors; Tramadol | 2015 |
Behavioral and pharmacological characteristics of bortezomib-induced peripheral neuropathy in rats.
Topics: Administration, Ophthalmic; Analgesics; Animals; Antineoplastic Agents; Axons; Bortezomib; Duloxetine Hydrochloride; Hyperalgesia; Mexiletine; Nerve Degeneration; Neurites; PC12 Cells; Peripheral Nervous System Diseases; Pregabalin; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tramadol | 2015 |
Goshajinkigan reduces bortezomib-induced mechanical allodynia in rats: Possible involvement of kappa opioid receptor.
Topics: Aconitum; Animals; Bortezomib; Drugs, Chinese Herbal; Hyperalgesia; Male; Naltrexone; Phytotherapy; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Tramadol | 2015 |
Unique action mechanisms of tramadol in global cerebral ischemia-induced mechanical allodynia.
Topics: Analgesics, Opioid; Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Male; Mice; Naltrexone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Tramadol | 2016 |
Antihyperalgesic effects of dexketoprofen and tramadol in a model of postoperative pain in mice - effects on glial cell activation.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug Combinations; Hyperalgesia; Ketoprofen; Male; Mice; Naloxone; Neuroglia; Pain Threshold; Pain, Postoperative; Tramadol | 2016 |
Bifunctional peptide-based opioid agonist/nociceptin antagonist ligand for dual treatment of nociceptive and neuropathic pain.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Indoles; Ligands; Male; Narcotic Antagonists; Neuralgia; Nociceptin; Nociceptive Pain; Oligopeptides; Opioid Peptides; Pain Measurement; Peptides; Phenalenes; Plethysmography; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Respiration; Time Factors; Tramadol | 2017 |
Effect of the combined use of tramadol and milnacipran on pain threshold in an animal model of fibromyalgia.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Cyclopropanes; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fibromyalgia; Hydrogen-Ion Concentration; Hyperalgesia; Injections, Intraperitoneal; Male; Milnacipran; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sodium Chloride; Time Factors; Tramadol | 2009 |
Efficacy of tramadol in combination with doxepin or venlafaxine in inhibition of nociceptive process in the rat model of neuropathic pain: an isobolographic analysis.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Doxepin; Drug Interactions; Drug Therapy, Combination; Hyperalgesia; Male; Neuralgia; Pain Measurement; Rats; Rats, Wistar; Statistics as Topic; Tramadol; Venlafaxine Hydrochloride | 2009 |
Spinal 5-HT7 receptors play an important role in the antinociceptive and antihyperalgesic effects of tramadol and its metabolite, O-Desmethyltramadol, via activation of descending serotonergic pathways.
Topics: Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred BALB C; Neural Pathways; Pain; Pain Measurement; Pain, Postoperative; Reaction Time; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tramadol | 2010 |
Altered nociceptive C fibre input to primary somatosensory cortex in an animal model of hyperalgesia.
Topics: Analgesics, Opioid; Animals; Brain Mapping; Electroencephalography; Evoked Potentials; Forelimb; Hindlimb; Hyperalgesia; Lasers; Nerve Fibers, Unmyelinated; Nociceptors; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reflex; Somatosensory Cortex; Tramadol; Ultraviolet Rays | 2011 |
Analgesic effects of tramadol, tramadol-gabapentin, and buprenorphine in an incisional model of pain in rats (Rattus norvegicus).
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Buprenorphine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Models, Animal; Pain, Postoperative; Postoperative Period; Rats; Rats, Sprague-Dawley; Tramadol; Weight-Bearing | 2011 |
Tramadol requirements may need to be increased for the perioperative management of pain in smokers.
Topics: Humans; Hyperalgesia; Pain, Postoperative; Perioperative Period; Receptors, Nicotinic; Smoking; Tramadol | 2011 |
Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice.
Topics: Acetone; Analgesics, Opioid; Animals; Capsaicin; Clomipramine; Disease Models, Animal; Formaldehyde; Hyperalgesia; Irritants; Male; Mice; Nociceptors; Orbit; Pruritus; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Tramadol; Transient Receptor Potential Channels; Trigeminal Nerve Injuries; Trigeminal Neuralgia; TRPA1 Cation Channel; TRPV Cation Channels; Vibrissae | 2011 |
Antihypersensitivity effects of tramadol hydrochloride in a rat model of postoperative pain.
Topics: Adrenergic Antagonists; Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Microdialysis; Motor Activity; Narcotic Antagonists; Norepinephrine; Pain Measurement; Pain Threshold; Pain, Postoperative; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Serotonin; Serotonin Antagonists; Spinal Cord; Time Factors; Tramadol | 2012 |
Combination of tramadol with minocycline exerted synergistic effects on a rat model of nerve injury-induced neuropathic pain.
Topics: Analgesics, Opioid; Animals; Anti-Bacterial Agents; Astrocytes; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Hyperalgesia; Male; Microglia; Minocycline; Neuralgia; Pain Measurement; Peripheral Nerve Injuries; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Spinal Cord; Tramadol | 2013 |
Tramadol induced paradoxical hyperalgesia.
Topics: Aged; Analgesics, Opioid; Chronic Pain; Female; Humans; Hyperalgesia; Male; Middle Aged; Tramadol | 2013 |
The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation.
Topics: Acute Disease; Amines; Analgesics, Opioid; Animals; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Indoles; Ion Channel Gating; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Mice; Peripheral Nervous System Diseases; Phenylenediamines; Physical Stimulation; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pyridines; Rats; Rats, Wistar; Spinal Nerves; Touch; Tramadol | 2004 |
Analysis of interaction between etoricoxib and tramadol against mechanical hyperalgesia of spinal cord injury in rats.
Topics: Animals; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Etoricoxib; Female; Hyperalgesia; Pain Threshold; Pyridines; Rats; Rats, Wistar; Spinal Cord Injuries; Sulfones; Tramadol | 2006 |
[Comparison of the suppressive effects of tramadol and low-dose ketamine on the patients with postoperative hyperalgesia after remifentanil-based anaesthesia].
Topics: Adult; Analgesics, Opioid; Anesthesia; Humans; Hyperalgesia; Ketamine; Male; Middle Aged; Pain, Postoperative; Piperidines; Postoperative Period; Remifentanil; Tramadol | 2005 |
Mu opioid receptor-dependent and independent components in effects of tramadol.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Psychological; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Hyperalgesia; Methysergide; Mice; Mice, Knockout; Narcotics; Pain Measurement; Reaction Time; Receptors, Opioid, mu; Reward; Serotonin Antagonists; Time Factors; Tramadol; Yohimbine | 2006 |
Altered antinociceptive efficacy of tramadol over time in rats with painful peripheral neuropathy.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Constriction, Pathologic; Dose-Response Relationship, Drug; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Time Factors; Tramadol; Yohimbine | 2007 |
Tramadol has a better potency ratio relative to morphine in neuropathic than in nociceptive pain models.
Topics: Analgesics, Opioid; Animals; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Injections, Intravenous; Male; Morphine; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sciatic Neuropathy; Time Factors; Tramadol | 2007 |
Increased tumor necrosis factor-alpha and prostaglandin E2 concentrations in the cerebrospinal fluid of rats with inflammatory hyperalgesia: the effects of analgesic drugs.
Topics: Acetaminophen; Administration, Oral; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Drug Combinations; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sulfonamides; Touch; Tramadol; Tumor Necrosis Factor-alpha | 2007 |
Tramadol is more effective than morphine and amitriptyline against ischaemic pain but not thermal pain in rats.
Topics: Amitriptyline; Analgesics; Animals; Female; Hot Temperature; Hyperalgesia; Ischemia; Male; Morphine; Motor Activity; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Tramadol | 2007 |
Postoperative administration of the analgesic tramadol, but not the selective cyclooxygenase-2 inhibitor parecoxib, abolishes postoperative hyperalgesia in a new model of postoperative pain in rats.
Topics: Analgesics, Opioid; Animals; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Hyperalgesia; Isoxazoles; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Tramadol | 2007 |
Analysis of the antinociceptive effect of systemic administration of tramadol and dexmedetomidine combination on rat models of acute and neuropathic pain.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Constriction, Pathologic; Dexmedetomidine; Drug Combinations; Hot Temperature; Hyperalgesia; Male; Pain; Pain Measurement; Peripheral Nervous System Diseases; Postural Balance; Rats; Rats, Wistar; Reaction Time; Sciatica; Time Factors; Tramadol | 2007 |
Milnacipran attenuates hyperalgesia and potentiates antihyperalgesic effect of tramadol in rats with mononeuropathic pain.
Topics: Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Drug Synergism; Hyperalgesia; Male; Milnacipran; Naloxone; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Tramadol | 2007 |
Anti-hyperalgesic effects of tramadol in the rat.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Formaldehyde; Hyperalgesia; Male; Nociceptors; Rats; Rats, Sprague-Dawley; Tramadol | 1998 |
Effects of tramadol on T lymphocyte proliferation and natural killer cell activity in rats with sciatic constriction injury.
Topics: Analgesics, Opioid; Animals; Cell Division; Hyperalgesia; Killer Cells, Natural; Ligation; Male; Rats; Rats, Wistar; Sciatic Nerve; Sciatica; T-Lymphocytes; Tramadol | 2001 |
Nefopam reduces thermal hypersensitivity in acute and postoperative pain models in the rat.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Hot Temperature; Hyperalgesia; Male; Morphine; Nefopam; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Tramadol | 2001 |
Effects of tramadol on behavioural indicators of colic pain in a rat model of ureteral calculosis.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Body Weight; Colic; Disease Models, Animal; Dose-Response Relationship, Drug; Estrous Cycle; Female; Hyperalgesia; Injections, Intraperitoneal; Muscle, Skeletal; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Tramadol; Ureteral Calculi | 2002 |