Compounds > tramadol
Page last updated: 2024-08-23

tramadol and Addiction, Opioid

tramadol has been researched along with Addiction, Opioid in 112 studies

Research

Studies (112)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.89)18.7374
1990's4 (3.57)18.2507
2000's19 (16.96)29.6817
2010's53 (47.32)24.3611
2020's35 (31.25)2.80

Authors

AuthorsStudies
Ameen, N; Bassiony, MM; Mahdy, RS; Salah El-Deen, GM1
Carbonell-Abella, C; Collins, GS; Delmestri, A; Diez-Perez, A; Englund, M; Khalid, S; Martinez-Laguna, D; Nogues, X; Prieto-Alhambra, D; Reyes, C; Strauss, VY; Tadrous, M; Turkiewicz, A; Xie, J1
Clausen, T; Hamina, A; Handal, M; Hjellvik, V; Odsbu, I; Skurtveit, S1
Garg, H; Marie-Westhiuzen, J; Pascoe, A1
Chalmers, BP; Chiu, YF; Gonzalez Della Valle, A; Joseph, AD; Lebowitz, J; LeBrun, DG1
Ghosh, S; Jain, R; Saifi, N; Sarkar, S1
Fahmy, C; Jackson, DB; Testa, A1
Balog, A; Benkő, R; Csenki, M; Csüllög, E; Csupor, D; Doró, P; Engi, Z; Matuz, M; Soós, G; Szok, D; Viola, R1
Acharya, M; Dayer, L; Hayes, CJ; Li, C; Martin, BC; Painter, JT2
Fouilhé Sam-Laï, N; Jouanjus, E; Khouri, C; Revol, B; Robert, M1
Abraham, C; Alleyne, S; Balasubramanian, S; Betteley, L; Booth, K; Carnes, D; Eldabe, S; Furlan, AD; Haywood, KL; Iglesias-Urrutia, CP; Krishnan, S; Lall, R; Manca, A; Mistry, D; Newton, S; Nichols, V; Noyes, J; Padfield, E; Rahman, A; Sandhu, HK; Seers, K; Shaw, J; Tang, NKY; Taylor, SJC; Tysall, C; Underwood, M1
Barrachina, J; Carvajal, C; Escorial, M; Margarit, C; Morales, D; Muriel, J; Peiró, AM1
Donat, M; Henares-Montiel, J; Moreno-Pulido, S; Prego-Meleiro, P; Pulido, J; Salazar, A; Sordo, L; Sotres-Fernandez, G1
Boumparis, N; Meyer, A; Naghizadeh, E; Noroozi, A; Rahimi-Movaghar, A; Schaub, MP; Wenger, A1
Maiti, R; Mishra, BR; Mohapatra, D; Padhan, M1
Cheng, S; Sams, C1
Bastos, FI; Bianchi, LM; Carvalho, RM; da Cunha, AJLA; de Magalhães-Barbosa, MC; Prata-Barbosa, A; Rodrigues-Santos, G1
Abrahamsen, B; Ernst, MT; Hansen, CA; Stougaard, M1
Abdeen, MS; Awaad, MI; El Habiby, MM; El Rasheed, AH; Hashim, MA; Ismail, GAW; Mohsen Ibrahim, NM1
Degenhardt, L; Gisev, N; Hall, WD; Roxburgh, A1
Awad, A; Basit, AW; Gaisford, S; Goyanes, A; Martorana, A; Ong, JJ; Stoyanov, E1
AuBuchon, JD; Cho, GJ; Lapidus, JB; Patel, KB; Santosa, KB; Skolnick, GB; Som, A; Waljee, JF1
Amin-Esmaeili, M; Ghadirzadeh, MR; Gholami, J; Mojtabai, R; Rahimi, H; Rahimi-Movaghar, A; Rostam-Abadi, Y; Safarcherati, A1
Babulovska, A; Simonovska, NK; Stefanovska, VV1
Bell, JE; Browne, JA; Chen, DQ; Haug, EC; Sequeira, SB; Werner, BC1
Agyemang-Duah, W; Akwasi, AG; Appiah-Brempong, E; Morgan, AK; Peprah, P1
Bergeria, C; Dunn, K; Huhn, AS; Strain, EC1
Bandieri, E; Bruera, E; Efficace, F; Luppi, M; Potenza, L1
Harburg, GR; Harris, K; Isoardi, KZ1
Ernst, MT; Jimenez-Solem, E; Laursen, MV; Mogensen, SH; Pottegård, A; Rasmussen, L; Sørensen, AMS1
Black, JC; Dart, RC; Iwanicki, JL; May, KP; Schwarz, J1
Grucza, R; Salas, J; Scherrer, JF; Tucker, J; Zhang, Z1
Gaviria-Mendoza, A; Machado-Alba, JE; Machado-Duque, ME; Serna-Echeverri, LS; Valladales-Restrepo, LF1
Cha, Y; Choi, HG; Choy, W; Hwang, JW; Jang, SY; Yoo, JI1
Bigelow, GE; Dunn, KE; Strain, EC; Tompkins, DA1
Kumar, V; Pathak, A; Rastogi, S1
Behzadfar, L; Mehdizadeh, H; Naserzadeh, P; Pourahmad, J; Rouini, MR; Sharifzadeh, M; Taghizadeh, G; Vousooghi, N; Yoonessi, A1
Burns, L; Degenhardt, L; Dobbins, T; Gisev, N; Hall, WD; Pearson, S; Roxburgh, A1
Akhgari, M; Amini-Shirazi, N; Iravani, FS1
Bebarta, VS; Borys, DJ; Maddry, JK; Ng, PC; Sessions, D1
Bolognesi, MP; Goltz, DE; Green, CL; Kildow, BJ; Politzer, CS; Seyler, TM1
Williams, JB1
Dunn, KE; Strain, EC; Tompkins, DA1
Casavant, MJ; Caupp, S; Shi, J; Spiller, HA; Steffan, J; Wheeler, KK; Xiang, H1
Amin, SA; Basha, MA; Elhelbawy, NG; Elnaidany, NF; Farag, AGA; Ibrahem, RA; Khodier, SA; Mahfouz, RZ; Mostafa, MMT1
Salm-Reifferscheidt, L1
Abd El Fattah, MA; Abd El-Rahman, SS; Abdel Salam, OME; Azmy, SM; El-Yamany, MF; Nada, SA; Nassar, NN1
Amato, L; Amin-Esmaeili, M; Gholami, J; Hoseinie, L; Rahimi-Movaghar, A; Yousefi-Nooraie, R1
Ardid, D; Authier, N; Chenaf, C; Delage, N; Delorme, J; Eschalier, A; Kaboré, JL; Mulliez, A; Pereira, B; Zenut, M1
Birke, H; Clausen, T; Ekholm, O; Fredheim, O; Sjøgren, P; Skurtveit, S1
Bigelow, GE; Dunn, KE; Huhn, AS; Schroeder, JR; Strain, EC; Tompkins, DA; Weerts, EM1
Kumar, S; Lal, R; Sarkar, S; Singh Balhara, YP; Varshney, M1
Ali, W; El-Gamel, O; El-Safty, I; Eltamany, E; Nada, A; Shouman, A1
Ibrahim, MA; Salah-Eldin, AE1
D'Alton, ME; Duffy, CR; Friedman, AM; Kern-Goldberger, AR; Landau, R; Mourad, M; Siddiq, Z; Wright, JD1
Habermann, EB; Hooten, WM; Jeffery, MM; Thiels, CA1
Guevara, A; Guevara, C; Guevara-Aguirre, J; Roa, JA1
de Wit, D; Koomen-Botman, I1
Juurlink, DN; Young, JW1
Babalonis, S; Campbell, C; Lofwall, MR; Nuzzo, PA; Siegel, A; Walsh, SL1
El Husseiny, RM; Ghaffar, HM; Mohamed, TM1
Cremer-Schaeffer, P; Glaeske, G; Greve, H; Grond, S; Hoffmann-Menzel, H; Münchberg, F; Radbruch, L; Scherbaum, N; Storz, E; Tholen, K; Zagermann-Muncke, P; Zieglgänsberger, W1
Hawkes, N1
Ferrari, A; Licata, M; Palazzoli, F; Tiraferri, I1
Bidel, Z; Carson, KV; Nazarzadeh, M1
Crane, J; Randall, C1
El Baz, H; Enabah, D; Moselhy, H1
Bertulli, R; Bossi, P; Granata, R; Saita, L1
El-Hadidy, MA; Helaly, AM1
Abdel-Ghani, MM; Atwa, SA; Bassiony, MM; El-Gohari, H; Raya, Y; Salah El-Deen, GM; Yousef, U1
Ghossoub, E; Talih, F1
Elassal, MA; Kamel, EM; Kandil, A; Khater, AH; Moustafa, R; Reda, W; Said, HG; Seifeldin, AF; Sobhy, MH1
Forrester, MB; Haynes, A; Kleinschmidt, K; Young, A1
Crow, JM1
Abo Elfetoh, N; Farghaly, HSM; Gabra, RH; Khedr, EM; Noaman, M1
Blanco, K; Cho, AK; Khalil, MA; Miotto, K; Rawson, R; Sasaki, JD1
Abdalla, A; Abdelghani, M; Bassiony, MM; El-Gohari, H; Hassan, MS; Ibrahim, DH; Salah El-Deen, GM; Youssef, UM1
Kanwar, P; Kumar, R; Sharma, DD; Sharma, RC1
Li, CS; Song, YG; Wang, SQ1
Ashby, R; Essary, AC; Ou, C; Stoehr, JD; Sucher, M1
Ahlner, J; Hägg, S; Jönsson, AK; Tjäderborn, M1
Bigelow, GE; Lanier, RK; Lofwall, MR; Mintzer, MZ; Strain, EC2
Mead, AN; O'Connor, EC1
Ginisty, S; Ksouda, K; Lépine, JP; Vorspan, F1
Allorge, D; Broly, F; Elkalioubie, A; Fourrier, F; Garat, A; Robriquet, L; Wiart, JF1
Abdel-Rahman, MS; Abdel-Zaher, AO; Elwasei, FM1
El-Feky, G; Kamel, R; Mahmoud, A1
Kahan, M; Mailis-Gagnon, A; Srivastava, A; Wilson, L1
Häkkinen, M; Launiainen, T; Ojanperä, I; Vuori, E1
Adams, EH; Cicero, TJ; Geller, A; Inciardi, JA; Muñoz, A; Schnoll, SH; Senay, EC; Woody, GE1
Dahlqvist, R; Näslund, S1
Schnoll, SH1
Brase, D; Fletcher, C; Rocha-Judd, R; Skipper, GE1
Adams, EH; Dart, RC; Knisely, JS; Schnoll, SH1
Atici, S; Cinel, I; Cinel, L; Doruk, N; Eskandari, G; Oral, U1
Adams, EH; Cicero, TJ; Geller, A; Inciardi, JA; Muñoz, A; Senay, EC; Woody, GE2
Epstein, DH; Jasinski, DR; Preston, KL1
Allen, KR1
Bigelow, GE; Carroll, CP; Preston, KL; Strain, EC; Walsh, SL1
Bigelow, GE; Lofwall, MR; Strain, EC; Walsh, SL1
Croissant, B; Grosshans, M; Mann, K1
Camí, J; Farré, M; Lamas, X1
Cossmann, M; Kohnen, C; Langford, R; McCartney, C1
Cai, ZJ; Cao, JQ; Lian, Z; Liu, ZM; Mu, Y; Ren, ZH; Zhou, WH1
DeGuiseppe, B; Leo, RJ; Narendran, R1
Kinder, DH; Leifheit, M; Milks, MM; Nichols, DE; Selken, J; Sprague, JE1
Jasinski, DR; Preston, KL; Testa, M1
Jasinski, DR; Preston, KL1

Reviews

8 review(s) available for tramadol and Addiction, Opioid

ArticleYear
Efficacy and safety of tramadol in the treatment of opioid withdrawal: A meta-analysis of randomized controlled trials.
    Addictive behaviors, 2023, Volume: 147

    Topics: Bayes Theorem; Buprenorphine; Clonidine; Humans; Methadone; Narcotics; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Tramadol

2023
Tramadol use and public health consequences in Iran: a systematic review and meta-analysis.
    Addiction (Abingdon, England), 2020, Volume: 115, Issue:12

    Topics: Adolescent; Adult; Analgesics, Opioid; Drug Overdose; Female; Humans; Iran; Male; Middle Aged; Opioid-Related Disorders; Public Health; Sex Factors; Tramadol; Young Adult

2020
Pharmacological therapies for management of opium withdrawal.
    The Cochrane database of systematic reviews, 2018, 06-21, Volume: 6

    Topics: Amantadine; Amines; Baclofen; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Methadone; Opioid-Related Disorders; Opium; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Tramadol

2018
Topical review on the abuse and misuse potential of tramadol and tilidine in Germany.
    Substance abuse, 2013, Volume: 34, Issue:3

    Topics: Analgesics, Opioid; Drug Therapy, Combination; Fraud; Germany; Humans; Incidence; Naloxone; Opioid-Related Disorders; Pain; Self Medication; Tilidine; Tramadol

2013
Trends in Tramadol: Pharmacology, Metabolism, and Misuse.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Pain; Analgesics, Opioid; Animals; Chronic Pain; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Compounding; Drug Interactions; Genotype; Humans; Opioid-Related Disorders; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Polymorphism, Genetic; Prescription Drug Misuse; Risk Factors; Tramadol

2017
[Treatment with tramadol can give rise to dependence and abuse].
    Lakartidningen, 2003, Feb-27, Volume: 100, Issue:9

    Topics: Analgesics, Opioid; Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol

2003
Abuse liability, behavioral pharmacology, and physical-dependence potential of opioids in humans and laboratory animals: lessons from tramadol.
    Biological psychology, 2006, Volume: 73, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Humans; Narcotic Antagonists; Opioid-Related Disorders; Product Surveillance, Postmarketing; Receptors, Opioid; Self Administration; Species Specificity; Tramadol; United States; United States Food and Drug Administration

2006
[Tolerance and safety of tramadol use. Results of international studies and data from drug surveillance].
    Drugs, 1997, Volume: 53 Suppl 2

    Topics: Analgesics, Opioid; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Clinical Trials, Phase IV as Topic; Humans; International Cooperation; Opioid-Related Disorders; Product Surveillance, Postmarketing; Tramadol

1997

Trials

11 trial(s) available for tramadol and Addiction, Opioid

ArticleYear
Reducing Opioid Use for Chronic Pain With a Group-Based Intervention: A Randomized Clinical Trial.
    JAMA, 2023, 05-23, Volume: 329, Issue:20

    Topics: Analgesics, Opioid; Chronic Pain; Female; Group Processes; Humans; Male; Middle Aged; Morphine; Opioid-Related Disorders; Self-Management; Tramadol

2023
Blended smartphone intervention for patients in opioid maintenance treatment in Iran: protocol for a randomized controlled trial.
    BMC psychiatry, 2023, 07-18, Volume: 23, Issue:1

    Topics: Adult; Analgesics, Opioid; Heroin; Humans; Iran; Opiate Substitution Treatment; Opioid-Related Disorders; Opium; Randomized Controlled Trials as Topic; Tramadol

2023
Efficacy of Tramadol Extended-Release for Opioid Withdrawal: A Randomized Clinical Trial.
    JAMA psychiatry, 2017, 09-01, Volume: 74, Issue:9

    Topics: Adult; Analgesics; Analgesics, Opioid; Buprenorphine; Clonidine; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol; Treatment Outcome; Young Adult

2017
Preliminary evidence of different and clinically meaningful opioid withdrawal phenotypes.
    Addiction biology, 2020, Volume: 25, Issue:1

    Topics: Adult; Analgesics; Buprenorphine; Clonidine; Cluster Analysis; Double-Blind Method; Female; Humans; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Phenotype; Severity of Illness Index; Substance Withdrawal Syndrome; Tramadol; Treatment Outcome

2020
Efficacy of extended-release tramadol for treatment of prescription opioid withdrawal: a two-phase randomized controlled trial.
    Drug and alcohol dependence, 2013, Nov-01, Volume: 133, Issue:1

    Topics: Adolescent; Adult; Analgesics, Opioid; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Opioid-Related Disorders; Prescription Drugs; Substance Withdrawal Syndrome; Tramadol

2013
Effects of repeated tramadol and morphine administration on psychomotor and cognitive performance in opioid-dependent volunteers.
    Drug and alcohol dependence, 2010, Oct-01, Volume: 111, Issue:3

    Topics: Adult; Cognition; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Morphine; Opioid-Related Disorders; Psychomotor Performance; Reaction Time; Tramadol

2010
Physical dependence potential of daily tramadol dosing in humans.
    Psychopharmacology, 2010, Volume: 211, Issue:4

    Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydromorphone; Male; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol

2010
Modest opioid withdrawal suppression efficacy of oral tramadol in humans.
    Psychopharmacology, 2007, Volume: 194, Issue:3

    Topics: Administration, Oral; Adult; Analgesics, Opioid; Cognition; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Psychomotor Performance; Substance Withdrawal Syndrome; Tramadol

2007
Acute effects of tramadol in methadone-maintained volunteers.
    Drugs, 1994, Volume: 47 Suppl 1

    Topics: Adult; Double-Blind Method; Humans; Male; Methadone; Opioid-Related Disorders; Tramadol

1994
Abuse potential and pharmacological comparison of tramadol and morphine.
    Drug and alcohol dependence, 1991, Volume: 27, Issue:1

    Topics: Adult; Arousal; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Morphine; Neurologic Examination; Opioid-Related Disorders; Reflex, Pupillary; Set, Psychology; Tramadol

1991
Effects of tramadol in humans: assessment of its abuse potential.
    NIDA research monograph, 1989, Volume: 95

    Topics: Arousal; Cyclohexanols; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Morphine Dependence; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Tramadol

1989

Other Studies

93 other study(ies) available for tramadol and Addiction, Opioid

ArticleYear
Prevalence, correlates, and consequences of attention-deficit/hyperactivity disorder in a clinical sample of adults with tramadol use in Egypt.
    The American journal on addictions, 2022, Volume: 31, Issue:1

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Cross-Sectional Studies; Egypt; Humans; Opioid-Related Disorders; Prevalence; Substance-Related Disorders; Tramadol

2022
Association of Tramadol vs Codeine Prescription Dispensation With Mortality and Other Adverse Clinical Outcomes.
    JAMA, 2021, 10-19, Volume: 326, Issue:15

    Topics: Accidental Falls; Ambulatory Care; Analgesics, Opioid; Cardiovascular Diseases; Cause of Death; Codeine; Databases, Factual; Delirium; Drug Prescriptions; Female; Fractures, Bone; Humans; Incidence; Male; Middle Aged; Opioid-Related Disorders; Propensity Score; Proportional Hazards Models; Retrospective Studies; Sleep Wake Disorders; Tramadol

2021
Describing long-term opioid use utilizing Nordic prescription registers-A Norwegian example.
    Basic & clinical pharmacology & toxicology, 2022, Volume: 130, Issue:4

    Topics: Analgesics, Opioid; Drug Prescriptions; Female; Humans; Opioid-Related Disorders; Reproducibility of Results; Tramadol

2022
COVID 19 unveils tramadol dependence.
    The Australian and New Zealand journal of psychiatry, 2022, Volume: 56, Issue:7

    Topics: Analgesics, Opioid; COVID-19; Humans; Opioid-Related Disorders; Tramadol

2022
The Effect of Preoperative Tramadol Use on Postoperative Opioid Prescriptions After Primary Total Hip and Knee Arthroplasty: An Institutional Experience of 11,000 Patients.
    The Journal of arthroplasty, 2022, Volume: 37, Issue:7S

    Topics: Aftercare; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Drug Prescriptions; Humans; Narcotics; Opioid-Related Disorders; Pain, Postoperative; Patient Discharge; Retrospective Studies; Tramadol

2022
Urinalysis based assessment of compliance and drug use patterns in patients prescribed tramadol: A cross-sectional study from a tertiary care centre.
    Asian journal of psychiatry, 2022, Volume: 71

    Topics: Adult; Analgesics; Analgesics, Opioid; Benzodiazepines; Buprenorphine; Cross-Sectional Studies; Humans; Male; Morphine; Opioid-Related Disorders; Pentazocine; Pheniramine; Reproducibility of Results; Tertiary Care Centers; Tramadol; Urinalysis

2022
Incarceration exposure and prescription opioid use during pregnancy.
    Drug and alcohol dependence, 2022, 06-01, Volume: 235

    Topics: Analgesics, Opioid; Female; Humans; Opioid-Related Disorders; Oxycodone; Pregnancy; Prescriptions; Tramadol

2022
Trends in opioid utilization in Hungary, 2006-2020: A nationwide retrospective study with multiple metrics.
    European journal of pain (London, England), 2022, Volume: 26, Issue:9

    Topics: Analgesics, Opioid; Cancer Pain; Drug Prescriptions; Drug Utilization; Humans; Hungary; Opioid-Related Disorders; Practice Patterns, Physicians'; Retrospective Studies; Tramadol

2022
Development of a potential opioid misuse measure from administrative dispensing data and contrasting opioid misuse among individuals on long-term tramadol, long-term short-acting hydrocodone or long-term short-acting oxycodone therapy in Arkansas.
    Current medical research and opinion, 2022, Volume: 38, Issue:11

    Topics: Adult; Analgesics, Opioid; Arkansas; Drug Overdose; Humans; Hydrocodone; Opioid-Related Disorders; Oxycodone; Retrospective Studies; Tramadol

2022
The opioid epidemic: A worldwide exploratory study using the WHO pharmacovigilance database.
    Addiction (Abingdon, England), 2023, Volume: 118, Issue:4

    Topics: Analgesics, Opioid; Bayes Theorem; Codeine; Fentanyl; Humans; Morphine; Opioid Epidemic; Opioid-Related Disorders; Oxycodone; Pharmacovigilance; Tramadol; World Health Organization

2023
Comparative Study of Opioid Initiation With Tramadol, Short-acting Hydrocodone, or Short-acting Oxycodone on Opioid-related Adverse Outcomes Among Chronic Noncancer Pain Patients.
    The Clinical journal of pain, 2023, Mar-01, Volume: 39, Issue:3

    Topics: Analgesics, Opioid; Chronic Pain; Humans; Hydrocodone; Opioid-Related Disorders; Oxycodone; Retrospective Studies; Tramadol

2023
Long-term deprescription in chronic pain and opioid use disorder patients: Pharmacogenetic and sex differences.
    Acta pharmaceutica (Zagreb, Croatia), 2023, Jun-01, Volume: 73, Issue:2

    Topics: Analgesics, Opioid; Chronic Pain; Cross-Sectional Studies; Cytochrome P-450 CYP2D6; Deprescriptions; Female; Humans; Male; Opioid-Related Disorders; Pharmacogenetics; Sex Characteristics; Tramadol

2023
Correlation Between Opioid Drug Prescription and Opioid-Related Mortality in Spain as a Surveillance Tool: Ecological Study.
    JMIR public health and surveillance, 2023, 06-28, Volume: 9

    Topics: Analgesics, Opioid; Drug Prescriptions; Fentanyl; Humans; Opiate Overdose; Opioid-Related Disorders; Spain; Tramadol

2023
Atypical Withdrawal Symptoms after Abrupt Tramadol Discontinuation: A Case Report.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:4

    Topics: Aged; Analgesics, Opioid; Female; Humans; Opioid-Related Disorders; Pain; Substance Withdrawal Syndrome; Tramadol; United States

2023
Shift in hospital opioid use during the COVID-19 pandemic in Brazil: a time-series analysis of one million prescriptions.
    Scientific reports, 2023, 10-11, Volume: 13, Issue:1

    Topics: Adult; Analgesics, Opioid; Brazil; COVID-19; Fentanyl; Humans; Methadone; Morphine; Opioid-Related Disorders; Pandemics; Prescriptions; Remifentanil; Sufentanil; Tramadol

2023
Tramadol prescribed use in general and chronic noncancer pain: a nationwide register-based cohort study of all patients above 16 years.
    Scandinavian journal of pain, 2019, 12-18, Volume: 20, Issue:1

    Topics: Analgesics, Opioid; Chronic Pain; Cohort Studies; Databases, Factual; Denmark; Drug Prescriptions; Female; Humans; Inappropriate Prescribing; Longitudinal Studies; Male; Middle Aged; Opioid-Related Disorders; Sex Factors; Tramadol

2019
Sexual dysfunction in tramadol hydrochloride use disorder male patients: a case-control study.
    International clinical psychopharmacology, 2020, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Case-Control Studies; Cross-Sectional Studies; Follicle Stimulating Hormone; Heroin Dependence; Humans; Luteinizing Hormone; Male; Middle Aged; Opioid-Related Disorders; Sexual Dysfunction, Physiological; Smoking; Testosterone; Tramadol; Young Adult

2020
Characteristics and circumstances of heroin and pharmaceutical opioid overdose deaths: Comparison across opioids.
    Drug and alcohol dependence, 2019, 12-01, Volume: 205

    Topics: Adolescent; Adult; Analgesics, Opioid; Australia; Chronic Pain; Drug Overdose; Drug Prescriptions; Female; Fentanyl; Heroin; Humans; Male; Methadone; Middle Aged; Morphine; Naloxone; Opioid-Related Disorders; Tramadol; Young Adult

2019
3D printed opioid medicines with alcohol-resistant and abuse-deterrent properties.
    International journal of pharmaceutics, 2020, Apr-15, Volume: 579

    Topics: Administration, Inhalation; Administration, Intravenous; Analgesics, Opioid; Cellulose; Drug Compounding; Drug Liberation; Ethanol; Opioid-Related Disorders; Particle Size; Polyethylene Glycols; Printing, Three-Dimensional; Tablets; Tramadol

2020
Opioid Prescribing and Use Patterns in Postsurgical Facial Trauma Patients.
    Plastic and reconstructive surgery, 2020, Volume: 145, Issue:3

    Topics: Adolescent; Adult; Analgesics, Opioid; Drug Prescriptions; Facial Bones; Female; Fracture Fixation; Humans; Inappropriate Prescribing; Male; Middle Aged; Opioid Epidemic; Opioid-Related Disorders; Pain, Postoperative; Postoperative Period; Practice Patterns, Physicians'; Retrospective Studies; Risk Factors; Skull Fractures; Tramadol; United States; Young Adult

2020
Non-Opioid Substances Acute Poisonings with Suicidal Intent in Patients with Opioid Use Disorder.
    Folia medica, 2020, 03-31, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Analgesics, Opioid; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Buprenorphine; Caustics; Cross-Sectional Studies; Drug Overdose; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Opiate Substitution Treatment; Opioid-Related Disorders; Poisoning; Republic of North Macedonia; Substance Abuse, Intravenous; Suicide, Attempted; Tramadol; Young Adult

2020
Preoperative Pain Management: Is Tramadol a Safe Alternative to Traditional Opioids Before Total Hip Arthroplasty?
    The Journal of arthroplasty, 2020, Volume: 35, Issue:10

    Topics: Analgesics, Opioid; Arthroplasty, Replacement, Hip; Humans; Opioid-Related Disorders; Pain, Postoperative; Retrospective Studies; Risk Factors; Tramadol

2020
"With tramadol, I ride like a Jaguar": a qualitative study of motivations for non-medical purpose tramadol use among commercial vehicle operators in Kumasi, Ghana.
    Substance abuse treatment, prevention, and policy, 2020, 07-23, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Automobile Driving; Female; Ghana; Health Status; Humans; Interpersonal Relations; Interviews as Topic; Libido; Male; Mental Health; Motivation; Narcotics; Opioid-Related Disorders; Qualitative Research; Tramadol; Young Adult

2020
Differences in patient-reported and observer-rated opioid withdrawal symptom etiology, time course, and relationship to clinical outcome.
    Drug and alcohol dependence, 2020, 10-01, Volume: 215

    Topics: Adult; Analgesics, Opioid; Animals; Buprenorphine, Naloxone Drug Combination; Clonidine; Female; Humans; Male; Middle Aged; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Patient Reported Outcome Measures; Substance Withdrawal Syndrome; Swine; Tramadol

2020
Independent Research on Cancer Pain Management in the Setting of Early Palliative Care: A Flywheel to Counteract General Opioid Misuse and Abuse.
    International journal of environmental research and public health, 2020, 09-28, Volume: 17, Issue:19

    Topics: Analgesics, Opioid; Humans; Neoplasms; Opioid-Related Disorders; Pain Management; Palliative Care; Tramadol

2020
Acute tramadol withdrawal: An unusual cause of severe acute behavioural disturbance.
    Drug and alcohol review, 2021, Volume: 40, Issue:5

    Topics: Analgesics, Opioid; Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol

2021
Use of tramadol and other analgesics following media attention and risk minimization actions from regulators: a Danish nationwide drug utilization study.
    European journal of clinical pharmacology, 2021, Volume: 77, Issue:4

    Topics: Aged; Aged, 80 and over; Analgesics; Communications Media; Denmark; Drug and Narcotic Control; Drug Substitution; Drug Utilization; Female; Government Regulation; Humans; Male; Middle Aged; Opioid-Related Disorders; Registries; Risk; Tramadol

2021
Tramadol non-medical use in Four European countries: A comparative analysis.
    Drug and alcohol dependence, 2020, 12-01, Volume: 217

    Topics: Adult; Analgesics, Opioid; Codeine; Cross-Sectional Studies; Europe; Female; Germany; Humans; Italy; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Prescription Drug Misuse; Prescription Drugs; Spain; Tramadol; United Kingdom; Young Adult

2020
Comparison of Opioids Prescribed for Patients at Risk for Opioid Misuse Before and After Publication of the Centers for Disease Control and Prevention's Opioid Prescribing Guidelines.
    JAMA network open, 2020, 12-01, Volume: 3, Issue:12

    Topics: Adult; Analgesics, Opioid; Centers for Disease Control and Prevention, U.S.; Codeine; Cross-Sectional Studies; Drug Prescriptions; Female; Guideline Adherence; Guidelines as Topic; Humans; Hydrocodone; Male; Middle Aged; Opioid-Related Disorders; Oxycodone; Practice Patterns, Physicians'; Tramadol; United States

2020
Use of Tramadol or Other Analgesics in Patients Treated in the Emergency Department as a Risk Factor for Opioid Use.
    Pain research & management, 2020, Volume: 2020

    Topics: Adult; Aged; Analgesics, Opioid; Cohort Studies; Colombia; Emergency Medical Services; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Morphine; Opioid-Related Disorders; Risk Factors; Tramadol; Treatment Outcome

2020
Effect of Opioids on All-cause Mortality and Opioid Addiction in Total Hip Arthroplasty: a Korea Nationwide Cohort Study.
    Journal of Korean medical science, 2021, Apr-05, Volume: 36, Issue:13

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Cohort Studies; Databases, Factual; Female; Hip Fractures; Humans; Male; Middle Aged; Opioid-Related Disorders; Pain, Postoperative; Proportional Hazards Models; Republic of Korea; Retrospective Studies; Risk Factors; Tramadol; Young Adult

2021
Tramadol addict: a rare but real challenge for the anaesthesiologist.
    Anaesthesiology intensive therapy, 2017, Volume: 49, Issue:3

    Topics: Analgesics, Opioid; Anesthesia; Anesthesiologists; Anesthesiology; Humans; Male; Middle Aged; Opioid-Related Disorders; Tramadol

2017
Mitochondrial impairments contribute to spatial learning and memory dysfunction induced by chronic tramadol administration in rat: Protective effect of physical exercise.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 10-03, Volume: 79, Issue:Pt B

    Topics: Animals; Brain; Exercise Therapy; Learning Disabilities; Male; Maze Learning; Memory Disorders; Mitochondria; Mitochondrial Diseases; Motor Activity; Narcotics; Neurotoxicity Syndromes; Opioid-Related Disorders; Random Allocation; Rats, Wistar; Reactive Oxygen Species; Spatial Learning; Tramadol

2017
Trends in heroin and pharmaceutical opioid overdose deaths in Australia.
    Drug and alcohol dependence, 2017, 10-01, Volume: 179

    Topics: Analgesics, Opioid; Australia; Drug Overdose; Fentanyl; Heroin; Humans; Morphine; Opioid-Related Disorders; Oxycodone; Pharmaceutical Preparations; Tramadol

2017
Forensic Toxicology Perspectives of Methadone-associated Deaths in Tehran, Iran, a 7-year Overview.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 122, Issue:4

    Topics: Adult; Cause of Death; Controlled Substances; Cross-Sectional Studies; Drug Overdose; Female; Forensic Toxicology; Humans; Iran; Laboratories; Male; Methadone; Methamphetamine; Middle Aged; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Tramadol; Young Adult

2018
Using Pill Identification Calls to Poison Centers as a Marker of Drug Abuse at Three Texas Military Bases.
    Southern medical journal, 2017, Volume: 110, Issue:11

    Topics: Analgesics, Opioid; Dextropropoxyphene; Humans; Hydrocodone; Military Facilities; Opioid-Related Disorders; Poison Control Centers; Retrospective Studies; Substance-Related Disorders; Tablets; Telephone; Texas; Tramadol

2017
Trends in Opioid Utilization Before and After Total Knee Arthroplasty.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:7S

    Topics: Adult; Aged; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Databases, Factual; Female; Humans; Male; Middle Aged; Odds Ratio; Opioid-Related Disorders; Osteoarthritis, Knee; Pain Management; Pain, Postoperative; Postoperative Period; Retrospective Studies; Risk Factors; Tramadol

2018
Tramadol Extended Release and Opioid Withdrawal Management-Legal Implications.
    JAMA psychiatry, 2018, 02-01, Volume: 75, Issue:2

    Topics: Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol

2018
Tramadol Extended-Release and Opioid Withdrawal Management-Legal Implications-Reply.
    JAMA psychiatry, 2018, 02-01, Volume: 75, Issue:2

    Topics: Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol

2018
Opioid drug poisonings in Ohio adolescents and young adults, 2002-2014.
    Clinical toxicology (Philadelphia, Pa.), 2018, Volume: 56, Issue:8

    Topics: Adolescent; Adolescent Behavior; Adult; Age Factors; Analgesics, Opioid; Child; Drug Overdose; Female; Forecasting; Humans; Male; Ohio; Opioid-Related Disorders; Oxycodone; Poison Control Centers; Sex Factors; Tramadol; Young Adult

2018
Tramadol (opioid) abuse is associated with a dose- and time-dependent poor sperm quality and hyperprolactinaemia in young men.
    Andrologia, 2018, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Analgesics, Opioid; Gonadotropins; Humans; Hyperprolactinemia; Hypogonadism; Male; Middle East; Opioid-Related Disorders; Prolactin; Semen Analysis; Smoking; Sperm Motility; Spermatogenesis; Testis; Testosterone; Tramadol

2018
Tramadol: Africa's opioid crisis.
    Lancet (London, England), 2018, 05-19, Volume: 391, Issue:10134

    Topics: Africa; Analgesics, Opioid; Health Policy; Humans; Opioid-Related Disorders; Population Surveillance; Substance Withdrawal Syndrome; Tramadol

2018
Does nicotine impact tramadol abuse? Insights from neurochemical and neurobehavioral changes in mice.
    Neurotoxicology, 2018, Volume: 67

    Topics: Analgesics, Opioid; Animals; Brain; Drug Therapy, Combination; Inflammation Mediators; Interpersonal Relations; Male; Maze Learning; Memory; Mice; Motor Activity; Nicotine; Nicotinic Agonists; Opioid-Related Disorders; Tramadol

2018
Prescription opioid analgesic use in France: Trends and impact on morbidity-mortality.
    European journal of pain (London, England), 2019, Volume: 23, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Chronic Pain; Codeine; Databases, Factual; Dextropropoxyphene; Female; Fentanyl; France; Humans; Male; Middle Aged; Mortality; Opioid-Related Disorders; Opium; Oxycodone; Prevalence; Proportional Hazards Models; Tramadol

2019
Tramadol use in Norway: A register-based population study.
    Pharmacoepidemiology and drug safety, 2019, Volume: 28, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Drug Prescriptions; Drug Utilization Review; Female; Follow-Up Studies; Humans; Male; Middle Aged; Norway; Opioid-Related Disorders; Pain Management; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prospective Studies; Registries; Tramadol

2019
Can Tramadol be Used for Maintenance Treatment of Opioid Dependence?
    Substance use & misuse, 2019, Volume: 54, Issue:3

    Topics: Adult; Analgesics, Opioid; Cross-Sectional Studies; Female; Humans; India; Male; Middle Aged; Opiate Substitution Treatment; Opioid-Related Disorders; Tramadol; Treatment Outcome

2019
Effect of tramadol addiction alone and its co-abuse with cannabis on urinary excretion of Copper, Zinc, and Calcium among Egyptian addicts.
    African health sciences, 2018, Volume: 18, Issue:3

    Topics: Adult; Calcium; Case-Control Studies; Copper; Creatinine; Cross-Sectional Studies; Egypt; Humans; Male; Marijuana Abuse; Opioid-Related Disorders; Tramadol; Young Adult; Zinc

2018
Chronic Addiction to Tramadol and Withdrawal Effect on the Spermatogenesis and Testicular Tissues in Adult Male Albino Rats.
    Pharmacology, 2019, Volume: 103, Issue:3-4

    Topics: Analgesics, Opioid; Animals; Apoptosis; Apoptosis Regulatory Proteins; Disease Models, Animal; Male; Opioid-Related Disorders; Oxidative Stress; Rats, Wistar; Spermatogenesis; Substance Withdrawal Syndrome; Testis; Tramadol

2019
Oral Opioid Use during Vaginal Delivery Hospitalizations.
    American journal of perinatology, 2020, Volume: 37, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Codeine; Databases, Factual; Delivery, Obstetric; Drug Utilization; Female; Hospitalization; Humans; Insurance, Health; Opioid-Related Disorders; Pain; Pregnancy; Tramadol; Young Adult

2020
Chronic use of tramadol after acute pain episode: cohort study.
    BMJ (Clinical research ed.), 2019, May-14, Volume: 365

    Topics: Acute Pain; Analgesics, Opioid; Drug Prescriptions; Elective Surgical Procedures; Humans; Opioid-Related Disorders; Pain, Postoperative; Patient Discharge; Retrospective Studies; Risk Factors; Tramadol

2019
Physician's role in prescribing opioids in developing countries.
    BMJ case reports, 2019, Jun-02, Volume: 12, Issue:6

    Topics: Adult; Analgesics, Opioid; Developing Countries; Ecuador; Humans; Injections, Intramuscular; Male; Migraine Disorders; Opioid-Related Disorders; Physician's Role; Practice Patterns, Physicians'; Tramadol

2019
[Neonatal abstinence syndrome after maternal use of tramadol].
    Nederlands tijdschrift voor geneeskunde, 2013, Volume: 157, Issue:9

    Topics: Adult; Analgesics, Opioid; Female; Humans; Infant, Newborn; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Placenta; Pregnancy; Pregnancy Complications; Tramadol

2013
Tramadol.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2013, May-14, Volume: 185, Issue:8

    Topics: Analgesics, Opioid; Humans; Opioid-Related Disorders; Tramadol

2013
Effects of tramadol, clonazepam, and their combination on brain mitochondrial complexes.
    Toxicology and industrial health, 2015, Volume: 31, Issue:12

    Topics: Analgesics, Opioid; Animals; Anticonvulsants; Brain; Clonazepam; Disease Models, Animal; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Male; Mitochondria; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Opioid-Related Disorders; Qualitative Research; Random Allocation; Rats; Substance-Related Disorders; Tramadol; Weight Loss

2015
Deaths from tramadol and legal highs reach new highs in England and Wales.
    BMJ (Clinical research ed.), 2013, Aug-30, Volume: 347

    Topics: Adult; Analgesics, Opioid; England; Female; Humans; Male; Mortality; Opioid-Related Disorders; Prescription Drug Misuse; Suicide; Tramadol; Wales; Young Adult

2013
Tramadol abuse in a binge pattern in a young depressed woman.
    European addiction research, 2014, Volume: 20, Issue:2

    Topics: Adult; Analgesics, Opioid; Depression; Female; Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol

2014
The association between tramadol hydrochloride misuse and other substances use in an adolescent population: Phase I of a prospective survey.
    Addictive behaviors, 2014, Volume: 39, Issue:1

    Topics: Adolescent; Alcohol Drinking; Amphetamine-Related Disorders; Analgesics, Opioid; Female; Humans; Iran; Male; Marijuana Smoking; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Odds Ratio; Opioid-Related Disorders; Opium; Prescription Drug Misuse; Prevalence; Prospective Studies; Sex Distribution; Substance-Related Disorders; Surveys and Questionnaires; Tramadol

2014
Tramadol deaths in Northern Ireland: a review of cases from 1996 to 2012.
    Journal of forensic and legal medicine, 2014, Volume: 23

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Depression; Drug Overdose; Female; Humans; Male; Middle Aged; Northern Ireland; Opioid-Related Disorders; Prescription Drug Diversion; Substance-Related Disorders; Tramadol; Young Adult

2014
Higher frequency of C.3435 of the ABCB1 gene in patients with tramadol dependence disorder.
    The American journal of drug and alcohol abuse, 2014, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Aged; Alleles; ATP Binding Cassette Transporter, Subfamily B; Case-Control Studies; Cross-Sectional Studies; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Opioid-Related Disorders; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Tramadol; Young Adult

2014
Rapid-onset opioids for the treatment of breakthrough cancer pain: two cases of drug abuse.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:5

    Topics: Analgesics, Opioid; Breakthrough Pain; Chemoradiotherapy; Coma; Fentanyl; Gastrointestinal Stromal Tumors; Humans; Male; Nasopharyngeal Neoplasms; Opioid-Related Disorders; Oxycodone; Palliative Care; Tramadol; Young Adult

2014
Medical and Psychiatric Effects of Long-Term Dependence on High Dose of tramadol.
    Substance use & misuse, 2015, Volume: 50, Issue:5

    Topics: Adult; Aggression; Anger; Anxiety; Depression; Hostility; Humans; Male; Obsessive-Compulsive Disorder; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol; Young Adult

2015
Adolescent tramadol use and abuse in Egypt.
    The American journal of drug and alcohol abuse, 2015, Volume: 41, Issue:3

    Topics: Adolescent; Egypt; Female; Humans; Male; Opioid-Related Disorders; Prevalence; Tramadol

2015
Moxonidine for tramadol withdrawal symptoms during detoxification.
    BMJ case reports, 2015, Jul-08, Volume: 2015

    Topics: Adult; Analgesics, Opioid; Antihypertensive Agents; Female; Humans; Imidazoles; Imidazoline Receptors; Opioid-Related Disorders; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Tramadol

2015
Latarjet Procedure for Anterior Shoulder Instability Due to Tramadol-Induced Seizures: A Multicenter Study.
    The American journal of sports medicine, 2016, Volume: 44, Issue:4

    Topics: Adult; Analgesics, Opioid; Female; Humans; Joint Instability; Male; Opioid-Related Disorders; Orthopedic Procedures; Patient Satisfaction; Prospective Studies; Seizures; Shoulder Dislocation; Shoulder Joint; Tramadol

2016
Trends in analgesic exposures reported to Texas Poison Centers following increased regulation of hydrocodone.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Codeine; Drug and Narcotic Control; Government Regulation; Heroin; Humans; Hydrocodone; Opioid-Related Disorders; Oxycodone; Poison Control Centers; Prescription Drug Misuse; Texas; Tramadol

2016
Biomedicine: Move over, morphine.
    Nature, 2016, 07-14, Volume: 535, Issue:7611

    Topics: Acute Pain; Adult; Chronic Pain; Drug Tolerance; Early Medical Intervention; Humans; Male; Morphine; Morphine Derivatives; Neural Inhibition; Oligopeptides; Opioid-Related Disorders; Pain Management; Peptides, Cyclic; Phenols; Receptors, Opioid, mu; Spinal Cord Stimulation; Tapentadol; Tramadol; Young Adult

2016
Cortical excitability in tramadol dependent patients: A transcranial magnetic stimulation study.
    Drug and alcohol dependence, 2016, Dec-01, Volume: 169

    Topics: Adult; Analgesics, Opioid; Cortical Excitability; Evoked Potentials, Motor; Humans; Male; Motor Cortex; Neural Inhibition; Opioid-Related Disorders; Rest; Seizures; Tramadol; Transcranial Magnetic Stimulation; Young Adult

2016
Cognitive Impairment and Tramadol Dependence.
    Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Analgesics, Opioid; Cognitive Dysfunction; Female; Humans; Male; Memory Disorders; Middle Aged; Opioid-Related Disorders; Tramadol; Young Adult

2017
Opium Withdrawal Delirium: Two Case Reports.
    Psychopharmacology bulletin, 2017, 01-26, Volume: 47, Issue:1

    Topics: Adult; Analgesics, Opioid; Anticonvulsants; Clonazepam; Delirium; Humans; Male; Middle Aged; Opioid-Related Disorders; Opium; Opium Dependence; Substance Withdrawal Syndrome; Tramadol

2017
Multiply organ dysfunction syndrome due to tramadol intoxication alone.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:7

    Topics: Adult; Humans; Male; Multiple Organ Failure; Narcotics; Opioid-Related Disorders; Poisoning; Respiratory Distress Syndrome; Tramadol

2009
The risk of tramadol abuse and dependence: findings in two patients.
    JAAPA : official journal of the American Academy of Physician Assistants, 2009, Volume: 22, Issue:7

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Counseling; Female; Headache; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Substance Abuse Detection; Tramadol

2009
Tramadol dependence: a survey of spontaneously reported cases in Sweden.
    Pharmacoepidemiology and drug safety, 2009, Volume: 18, Issue:12

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Analgesics, Opioid; Data Collection; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Opioid-Related Disorders; Risk Factors; Substance Withdrawal Syndrome; Sweden; Tramadol

2009
Tramadol acts as a weak reinforcer in the rat self-administration model, consistent with its low abuse liability in humans.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 96, Issue:3

    Topics: Analgesics, Opioid; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Morphine; Opioid-Related Disorders; Piperidines; Rats; Receptors, Opioid, mu; Reinforcement Schedule; Remifentanil; Self Administration; Tramadol

2010
A case report of tramadol abuse-associated tics.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:5

    Topics: Adult; Humans; Male; Opioid-Related Disorders; Tics; Tramadol

2010
Near-fatal tramadol cardiotoxicity in a CYP2D6 ultrarapid metabolizer.
    European journal of clinical pharmacology, 2011, Volume: 67, Issue:8

    Topics: Adult; Analgesics, Opioid; Cytochrome P-450 CYP2D6; Drug Monitoring; Drug Overdose; Epinephrine; Female; Genotype; Heart Arrest; Humans; Metabolic Detoxication, Phase I; Myocardial Stunning; Opioid-Related Disorders; Tramadol; Young Adult

2011
Protective effect of Nigella sativa oil against tramadol-induced tolerance and dependence in mice: role of nitric oxide and oxidative stress.
    Neurotoxicology, 2011, Volume: 32, Issue:6

    Topics: Analgesics, Opioid; Animals; Antioxidants; Behavior, Animal; Brain; Drug Tolerance; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutathione; Male; Malondialdehyde; Mice; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Opioid-Related Disorders; Oxidative Stress; Pain Threshold; Plant Oils; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Time Factors; Tramadol

2011
Double-phase hydrogel for buccal delivery of tramadol.
    Drug development and industrial pharmacy, 2012, Volume: 38, Issue:4

    Topics: Administration, Buccal; Analgesics, Opioid; Animals; Biocompatible Materials; Biological Availability; Chickens; Chronic Pain; Delayed-Action Preparations; Drug Delivery Systems; Humans; Hydrogels; Male; Microspheres; Opioid-Related Disorders; Particle Size; Polyvinyl Alcohol; Rats; Rats, Wistar; Tramadol

2012
Canadian guideline for safe and effective use of opioids for chronic noncancer pain: clinical summary for family physicians. Part 1: general population.
    Canadian family physician Medecin de famille canadien, 2011, Volume: 57, Issue:11

    Topics: Analgesics, Opioid; Benzodiazepines; Canada; Chronic Pain; Codeine; Humans; Hydromorphone; Mass Screening; Opioid-Related Disorders; Oxycodone; Patient Education as Topic; Sleep Apnea Syndromes; Tramadol

2011
Comparison of fatal poisonings by prescription opioids.
    Forensic science international, 2012, Oct-10, Volume: 222, Issue:1-3

    Topics: Accidents; Adolescent; Adult; Analgesics, Opioid; Buprenorphine; Central Nervous System Depressants; Codeine; Dextropropoxyphene; Drug Overdose; Ethanol; Fentanyl; Finland; Forensic Toxicology; Humans; Hypnotics and Sedatives; Methadone; Morphine; Opioid-Related Disorders; Oxycodone; Poisoning; Prescription Drug Misuse; Suicide; Tramadol; Young Adult

2012
Physical dependence on Ultram (tramadol hydrochloride): both opioid-like and atypical withdrawal symptoms occur.
    Drug and alcohol dependence, 2003, Apr-01, Volume: 69, Issue:3

    Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Drug and Narcotic Control; Humans; Opioid-Related Disorders; Psychoses, Substance-Induced; Risk Factors; Substance Withdrawal Syndrome; Tramadol; United States; United States Food and Drug Administration

2003
The emperor' s new clothes.
    Journal of addictive diseases, 2003, Volume: 22, Issue:4

    Topics: Analgesics, Opioid; Buprenorphine; Clinical Trials as Topic; Clonidine; Heroin Dependence; Humans; Methadone; Narcotic Antagonists; Opioid-Related Disorders; Retrospective Studies; Substance Withdrawal Syndrome; Tramadol

2003
Tramadol abuse and dependence among physicians.
    JAMA, 2004, Oct-20, Volume: 292, Issue:15

    Topics: Alabama; Humans; Michigan; Opioid-Related Disorders; Physicians; Tramadol

2004
Tramadol abuse and dependence among physicians.
    JAMA, 2005, Apr-27, Volume: 293, Issue:16

    Topics: Humans; Opioid-Related Disorders; Physicians; Tramadol

2005
Liver and kidney toxicity in chronic use of opioids: an experimental long term treatment model.
    Journal of biosciences, 2005, Volume: 30, Issue:2

    Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Creatinine; Dose-Response Relationship, Drug; Kidney; L-Lactate Dehydrogenase; Lipid Peroxides; Liver; Male; Malondialdehyde; Morphine; Opioid-Related Disorders; Rats; Rats, Wistar; Tramadol

2005
Rates of abuse of tramadol remain unchanged with the introduction of new branded and generic products: results of an abuse monitoring system, 1994-2004.
    Pharmacoepidemiology and drug safety, 2005, Volume: 14, Issue:12

    Topics: Acetaminophen; Analgesics, Opioid; Drug Prescriptions; Drugs, Generic; Humans; Narcotics; Opioid-Related Disorders; Pain; Product Surveillance, Postmarketing; Tramadol; United States

2005
Tramadol addiction.
    Prescrire international, 2005, Volume: 14, Issue:77

    Topics: Adolescent; Humans; Lebanon; Male; Narcotics; Opioid-Related Disorders; Tramadol

2005
Interference by venlafaxine ingestion in the detection of tramadol by liquid chromatography linked to tandem mass spectrometry for the screening of illicit drugs in human urine.
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Chromatography, Liquid; Cyclohexanols; Drug Interactions; False Positive Reactions; Humans; Narcotics; Opioid-Related Disorders; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tramadol; Venlafaxine Hydrochloride

2006
Assessment of agonist and antagonist effects of tramadol in opioid-dependent humans.
    Experimental and clinical psychopharmacology, 2006, Volume: 14, Issue:2

    Topics: Adult; Analgesics, Opioid; Heart Rate; Humans; Hydromorphone; Middle Aged; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Tramadol

2006
The Diversion of Ultram, Ultracet, and generic tramadol HCL.
    Journal of addictive diseases, 2006, Volume: 25, Issue:2

    Topics: Acetaminophen; Advisory Committees; Cross-Sectional Studies; Data Collection; Drug and Narcotic Control; Drug Approval; Drug Combinations; Drug Prescriptions; Drugs, Generic; Humans; Illicit Drugs; Marketing; Narcotics; Opioid-Related Disorders; Product Surveillance, Postmarketing; Risk; Tramadol; United States; United States Food and Drug Administration

2006
[Rapid inpatient tramadol-detoxification using oxcarbazepine].
    Psychiatrische Praxis, 2008, Volume: 35, Issue:3

    Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Male; Narcotics; Opioid-Related Disorders; Oxcarbazepine; Patient Admission; Substance Withdrawal Syndrome; Tramadol

2008
Drug dependence and abuse potential of tramadol.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:1

    Topics: Adult; Female; Humans; Male; Opioid-Related Disorders; Substance Abuse Detection; Substance Withdrawal Syndrome; Tramadol

1999
Methadone detoxification of tramadol dependence.
    Journal of substance abuse treatment, 2000, Volume: 19, Issue:3

    Topics: Acute Disease; Dose-Response Relationship, Drug; Female; Humans; Methadone; Middle Aged; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol

2000
In vivo microdialysis and conditioned place preference studies in rats are consistent with abuse potential of tramadol.
    Synapse (New York, N.Y.), 2002, Volume: 43, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Psychological; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Male; Microdialysis; Neurons; Nucleus Accumbens; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Tramadol

2002