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tosufloxacin and Diarrhea

tosufloxacin has been researched along with Diarrhea in 2 studies

tosufloxacin: quinolone anti-infective agent; structure given in first source
tosufloxacin : A racemate comprising equimolar amounts of (R)- and (S)-tosufloxacin.
7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid : A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 3-aminopyrrolidin-1-yl substituents at positions 1, 6 and 7 respectively.

Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.

Research Excerpts

ExcerptRelevanceReference
"For the purpose of evaluation of clinical efficacy, safety and usefulness on Salmonella enteritis, T-3262 (Tosufloxacin tosilate), a newly developed pyridone-carboxylic acid derivative, was administered to a total of 103 patients and carriers."9.06[Clinical trial of T-3262 (Tosufloxacin tosilate) on Salmonella enteritis, and fecal drug concentration and change in the fecal microflora in the acute diarrheal patients. Japan Research Committee of T-3262, Research Group for Acute Infectious Enteritis]. ( Aoki, T; Kamimura, M; Kanehisa, N; Matsubara, Y; Nitia, Y; Sagara, H; Seo, T; Shimizu, N; Takizawa, Y; Tomizawa, I, 1989)
"Tosufloxacin (A-60969 HCl), a new quinolone with broad activity against gram-positive and anaerobic organisms, was compared in vitro with other quinolones against bacterial pathogens of diarrhea."7.68In vitro activities of tosufloxacin, temafloxacin, and A-56620 against pathogens of diarrhea. ( Bryan, JP; Krieg, RE; Perine, PL; Sheffield, J; Wagner, K; Waters, C, 1990)
"For the purpose of evaluation of clinical efficacy, safety and usefulness on Salmonella enteritis, T-3262 (Tosufloxacin tosilate), a newly developed pyridone-carboxylic acid derivative, was administered to a total of 103 patients and carriers."5.06[Clinical trial of T-3262 (Tosufloxacin tosilate) on Salmonella enteritis, and fecal drug concentration and change in the fecal microflora in the acute diarrheal patients. Japan Research Committee of T-3262, Research Group for Acute Infectious Enteritis]. ( Aoki, T; Kamimura, M; Kanehisa, N; Matsubara, Y; Nitia, Y; Sagara, H; Seo, T; Shimizu, N; Takizawa, Y; Tomizawa, I, 1989)
"Tosufloxacin (A-60969 HCl), a new quinolone with broad activity against gram-positive and anaerobic organisms, was compared in vitro with other quinolones against bacterial pathogens of diarrhea."3.68In vitro activities of tosufloxacin, temafloxacin, and A-56620 against pathogens of diarrhea. ( Bryan, JP; Krieg, RE; Perine, PL; Sheffield, J; Wagner, K; Waters, C, 1990)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bryan, JP1
Waters, C1
Sheffield, J1
Krieg, RE1
Perine, PL1
Wagner, K1
Aoki, T1
Matsubara, Y1
Sagara, H1
Shimizu, N1
Tomizawa, I1
Takizawa, Y1
Nitia, Y1
Seo, T1
Kamimura, M1
Kanehisa, N1

Trials

1 trial available for tosufloxacin and Diarrhea

ArticleYear
[Clinical trial of T-3262 (Tosufloxacin tosilate) on Salmonella enteritis, and fecal drug concentration and change in the fecal microflora in the acute diarrheal patients. Japan Research Committee of T-3262, Research Group for Acute Infectious Enteritis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1989, Volume: 63, Issue:7

    Topics: 4-Quinolones; Adult; Aged; Anti-Infective Agents; Clinical Trials as Topic; Diarrhea; Enteritis; Fec

1989

Other Studies

1 other study available for tosufloxacin and Diarrhea

ArticleYear
In vitro activities of tosufloxacin, temafloxacin, and A-56620 against pathogens of diarrhea.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Diarrhea; Fluoroquinolones; H

1990