Page last updated: 2024-11-05

tosufloxacin and Bacterial Infections

tosufloxacin has been researched along with Bacterial Infections in 14 studies

tosufloxacin: quinolone anti-infective agent; structure given in first source
tosufloxacin : A racemate comprising equimolar amounts of (R)- and (S)-tosufloxacin.
7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid : A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 3-aminopyrrolidin-1-yl substituents at positions 1, 6 and 7 respectively.

Bacterial Infections: Infections by bacteria, general or unspecified.

Research Excerpts

ExcerptRelevanceReference
"In a multicenter trial at 17 institutions, the usefulness of an oral dose of 300 mg of tosufloxacin (TFLX) twice a day for 14 days were assessed in the management of chronic bacterial prostatitis (CBP) diagnosed by Meares and Stamey method."9.07[Clinical studies of tosufloxacin on chronic bacterial prostatitis]. ( Hirano, A; Ikeuchi, T; Kawamura, N; Onodera, S; Osada, T; Satomi, Y; Suzuki, K; Yamamoto, Y; Yoshimura, S, 1993)
"To objectively assess azithromycin (AZM) for its clinical efficacy, safety and usefulness in the treatment of acute odontogenic infections (periodontitis, pericoronitis and osteitis of the jaw), a double-blind, randomized, multi-center trial was conducted in which tosufloxacin tosilate (TFLX) was used as the control drug."5.08[Comparative clinical study of azithromycin with tosufloxacin tosilate in the treatment of acute odontogenic infection]. ( Kaneko, A; Karakida, K; Katoh, H; Naitoh, H; Sakamoto, H; Sasaki, J; Shiiki, K; Tomita, F; Yamane, N; Yoshida, H, 1995)
"In a multicenter trial at 17 institutions, the usefulness of an oral dose of 300 mg of tosufloxacin (TFLX) twice a day for 14 days were assessed in the management of chronic bacterial prostatitis (CBP) diagnosed by Meares and Stamey method."5.07[Clinical studies of tosufloxacin on chronic bacterial prostatitis]. ( Hirano, A; Ikeuchi, T; Kawamura, N; Onodera, S; Osada, T; Satomi, Y; Suzuki, K; Yamamoto, Y; Yoshimura, S, 1993)
"Tosufloxacin was as effective as levofloxacin when administered twice daily for 2 days as prophylaxis for TBP, which suggests that this regimen is useful for reducing the clinical and febrile infection rate following TBP."2.73Antibiotic prophylaxis for transrectal prostate biopsy: a prospective randomized study of tosufloxacin versus levofloxacin. ( Ishitoya, S; Kamoto, T; Ogawa, O; Okumura, K; Segawa, T; Yamamoto, S, 2008)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's8 (57.14)18.2507
2000's2 (14.29)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rosen, T1
Chu, DT1
Lico, IM1
Fernandes, PB1
Marsh, K1
Shen, L1
Cepa, VG1
Pernet, AG1
Sunakawa, K1
Onai, K1
Yamazaki, T1
Sasaki, J2
Yamamoto, S1
Ishitoya, S1
Segawa, T1
Kamoto, T1
Okumura, K1
Ogawa, O1
Kaneko, A1
Karakida, K1
Shiiki, K1
Sakamoto, H1
Naitoh, H1
Yamane, N1
Tomita, F1
Katoh, H1
Yoshida, H1
Mori, S1
Ohashi, K1
Akiyama, H1
Shoji, H1
Sato, H1
Tanikawa, S1
Sakamaki, H1
Onozawa, Y1
Ikeuchi, T1
Kawamura, N1
Suzuki, K1
Onodera, S1
Osada, T1
Hirano, A1
Satomi, Y1
Yoshimura, S1
Yamamoto, Y1
Fukuoka, Y1
Ikeda, Y1
Yamashiro, Y1
Takahata, M1
Todo, Y1
Narita, H1
Masuda, N1
Takahashi, Y1
Otsuki, M1
Ibuki, E1
Miyoshi, H1
Nishino, T1
Koga, H1
Aoyagi, K1
Yoshimura, R1
Kimura, Y1
Iida, M1
Fujishima, M1
Nord, CE1
Edlund, C1
Shimada, K1
Aoki, T1
Matsubara, Y1
Sagara, H1
Tomizawa, I1
Takizawa, Y1
Nitta, Y1
Seo, T1
Kamimura, M1
Masuda, G1
Negishi, M1
Fujimaki, K1
Noumi, T1
Saikawa, I1
Inoue, M1
Mitsuhashi, S1

Reviews

2 reviews available for tosufloxacin and Bacterial Infections

ArticleYear
[Azithromycin in dentistry and oral surgery].
    The Japanese journal of antibiotics, 2000, Volume: 53 Suppl B

    Topics: Anti-Infective Agents; Azithromycin; Bacteria; Bacterial Infections; Clinical Trials as Topic; Doubl

2000
[Tosufloxacin tosilate].
    The Japanese journal of antibiotics, 1990, Volume: 43, Issue:4

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Drug Resistance, Micro

1990

Trials

5 trials available for tosufloxacin and Bacterial Infections

ArticleYear
Antibiotic prophylaxis for transrectal prostate biopsy: a prospective randomized study of tosufloxacin versus levofloxacin.
    International journal of urology : official journal of the Japanese Urological Association, 2008, Volume: 15, Issue:7

    Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Biopsy; Cystitis; Fluoroq

2008
[Comparative clinical study of azithromycin with tosufloxacin tosilate in the treatment of acute odontogenic infection].
    The Japanese journal of antibiotics, 1995, Volume: 48, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Azithromyc

1995
Tosulfloxacin versus norfloxacin for prevention of infections in chemotherapy-induced neutropenic patients.
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1994, Volume: 68, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antineoplastic Agents; Bacterial Infections; Drug Ev

1994
[Clinical studies of tosufloxacin on chronic bacterial prostatitis].
    Hinyokika kiyo. Acta urologica Japonica, 1993, Volume: 39, Issue:7

    Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Dru

1993
[Clinical trial of T-3262 on acute enteritis. Japan Research Committee of T-3262, Research Group for Acute Infectious Enteritis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1989, Volume: 63, Issue:6

    Topics: 4-Quinolones; Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Bacteria; Bacterial Inf

1989

Other Studies

7 other studies available for tosufloxacin and Bacterial Infections

ArticleYear
Design, synthesis, and properties of (4S)-7-(4-amino-2-substituted-pyrrolidin-1-yl)quinolone-3-carboxylic acids.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Dogs; Fluoroqui

1988
[Intractable pediatric infectious disease: examining the ability of a new drug, tosufloxacin tosilate hydrate for pediatric (discussion)].
    The Japanese journal of antibiotics, 2011, Volume: 64, Issue:5

    Topics: Administration, Oral; Age Factors; Anti-Bacterial Agents; Bacterial Infections; Child; Fluoroquinolo

2011
In vitro and in vivo antibacterial activities of T-3761, a new quinolone derivative.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:3

    Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Lung Diseases

1993
In vitro and in vivo antibacterial activities of CS-940, a new 6-fluoro-8-difluoromethoxy quinolone.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Evaluation, Preclinical; F

1996
Can quinolones cause hemorrhagic colitis of late onset? Report of three cases.
    Diseases of the colon and rectum, 1999, Volume: 42, Issue:11

    Topics: Acute Disease; Adult; Anti-Infective Agents; Bacterial Infections; Colitis; Colonoscopy; Enoxacin; F

1999
Efficacy of tosufloxacin in the treatment of experimentally induced intra-abdominal infections in rats.
    Drugs under experimental and clinical research, 1992, Volume: 18, Issue:3

    Topics: 4-Quinolones; Abscess; Animals; Anti-Infective Agents; Bacterial Infections; Disease Models, Animal;

1992
In vitro and in vivo antibacterial activities of T-3262, a new fluoroquinolone.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Resistance, Microbial; Escheric

1988