torpedo has been researched along with Anti-MuSK Myasthenia Gravis in 139 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 51 (36.69) | 18.7374 |
| 1990's | 73 (52.52) | 18.2507 |
| 2000's | 10 (7.19) | 29.6817 |
| 2010's | 5 (3.60) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agius, MA; Fairclough, RH; Friend, A; Gudipati, E; Morell, SW; Page, NA; Richman, DP; Trinh, VB | 1 |
| Li, J; Liu, Q; Lu, JY; Tian, FF; Wang, YZ; Yan, M; Yang, H; Zhang, JM; Zhou, WB | 1 |
| Fairclough, RH; Foster, AJ; Trinh, VB | 1 |
| Wang, R; Wang, Y; Zhang, L; Zhang, P | 1 |
| Allman, W; Christadoss, P; Deymeer, F; Li, J; Qi, H; Saini, SS; Saruhan-Direskeneli, G; Tüzün, E; Yilmaz, V | 1 |
| Artinger, M; Bhattacharya, P; Grimme, S; Meriggioli, MN; Prabahakar, BS; Sheng, JR; Stowell, MH | 1 |
| Adams, RN; Drachman, DB; Johnson, MM; Lenardo, MJ; Lobito, AA; Lopes, MF; McFarland, H; Miagkov, A; Palardy, GR; Yang, B | 1 |
| Büttner, J; Hossann, M; Kreilinger, U; Li, Z; Shi, Y; Trommer, WE; Vogel, PD; Wise, JG; Yuan, J | 1 |
| Lantsova, VB; Sepp, EK | 1 |
| Christadoss, P; Li, J; Saini, SS; Tüzün, E; Yang, H | 1 |
| Ben-David, H; Dayan, M; Mozes, E; Sela, M; Sharabi, A | 1 |
| Abramsky, O; Argov, Z; Brenner, T; Zielinski, A | 1 |
| Elfman, L | 1 |
| Komai, K; Sakato, S; Takamori, M | 1 |
| Abramsky, O; Brenner, T | 2 |
| Gullick, W; Lindstrom, J; Tzartos, S | 1 |
| Cleveland, WL; Erlanger, BF; Freimuth, PI; Penn, AS; Treptow, N; Wassermann, NH; Wentzel, S | 1 |
| Fulpius, BW | 1 |
| Kasai, M; Takamori, M | 1 |
| Birnberger, KL; Heinz, F; Hohlfeld, R; Kalden, JR; Kalies, I; Wekerle, H | 1 |
| Gullick, W; Hochschwender, S; Jacob, M; Lindstrom, J; Montal, M; Sargent, P; Swanson, L; Tzartos, S | 1 |
| Bionda, A; De Baets, MH; Lindstrom, JM; Theophilopoulos, AN; Tzartos, SJ; Weigle, WO | 1 |
| Bever, CT; Bock, E; Chang, HW; Jaffe, IA; Penn, AS | 1 |
| Lindstrom, JM | 1 |
| Chang, HW; Nastuk, WL; Niemi, WD; Plescia, AM; Plescia, OJ | 1 |
| Berman, PW; Heinemann, S; Klier, FG; Patrick, J; Steinbach, JH | 1 |
| Albuquerque, EX; Eldefrawi, ME; Giddings, FD; Graham, WF; Hudson, CS; Johnson, TJ; Mayer, RF; Rash, JE | 1 |
| Arnason, BG; Burres, SA; Kanter, ME; Richman, DP | 1 |
| De Baets, MH; Einarson, B; Lindstrom, JM; Weigle, WO | 1 |
| Hayashi, K; Kohno, M | 1 |
| Farach, MC; Martinez-Carrion, M; Mihovilovic, M; Paraschos, A | 1 |
| Abramsky, O; Brenner, T; Zielinski, A | 1 |
| Barkas, T; Simpson, JA | 2 |
| Alliod, C; Fulpius, BW; James, RW; Lefvert, AK | 1 |
| Tu, LH | 1 |
| Einarson, B; Lindstrom, J; Tzartos, S | 1 |
| Atassi, MZ; Oshima, M; Pachner, AR | 1 |
| Atassi, MZ | 1 |
| Link, H; Link, J; Ma, CG; Olsson, T; Xiao, BG; Zhang, GX | 1 |
| He, B; Huang, J; Link, H; Olsson, T; Wang, ZY | 1 |
| Beroukhim, R; Unwin, N | 1 |
| Bellone, M; Conti-Fine, BM; Infante, AJ; Karachunski, PI; Ostlie, N | 1 |
| Apostolski, S; Bartlett, RR; Damjanovic, M; Isakovic, K; Kosec, D; Vidic-Dankovic, B | 1 |
| Conti-Tronconi, BM; Howard, JF; Manfredi, AA; Moiola, L; Protti, MP; Yuen, MH | 1 |
| Aimé-Sempé, C; Berrih-Aknin, S; Bruand, C; Cohen-Kaminsky, S; Klingel-Schmitt, I; Truffault, F | 1 |
| Bakhiet, M; Link, H; Ma, CG; Olsson, T; Xiao, BG; Zhang, GX | 1 |
| Araga, S; Blalock, JE | 1 |
| Damjanović, M; Isaković, K; Kosec, D; Vidić-Danković, B | 1 |
| Atassi, MZ; Christadoss, P; Oshima, M; Shenoy, M | 1 |
| Infante, AJ; Kraig, E; Pierce, JL; Zborowski, KA | 1 |
| Asthana, D; Balderas, RS; Fujii, Y; Kono, DH; Lindstrom, J; Smith, LR; Theofilopoulos, AN | 1 |
| Currier, P; Hu, JY; Infante, AJ; Sette, A; Southwood, S; Wall, KA | 1 |
| Link, H; Qiao, J; Wang, ZY | 2 |
| Huang, WX; Link, H; Olsson, T; Qiao, J; Wang, ZY | 1 |
| Takamori, M | 1 |
| Baggi, F; Batocchi, AP; Beeson, D; Harcourt, G; Hawke, S; Jacobson, L; Matsuo, H; Moody, AM; Nagvekar, N; Willcox, N | 1 |
| Christadoss, P; Shenoy, M | 1 |
| Araga, S; Blalock, JE; LeBoeuf, RD | 1 |
| Hara, H; Hayashi, K; Itoh, N; Nishitani, H; Ohta, K; Ohta, M | 1 |
| Bos, NA; De Baets, MH; Graus, YM; van Breda Vriesman, PJ; Verschuuren, JJ | 1 |
| Conti-Tronconi, BM; Lindstrom, JM; Ostlie, N; Wahlsten, JL; Wu, XD | 1 |
| Atassi, MZ; Oshima, M; Rosenberg, JS | 1 |
| Barohn, RJ; Clarkin, KZ; Infante, AJ; Infante, PD; Iturriaga, E; Jackson, CE; Kraig, E; Krolick, KA; Talib, S; Tami, J | 1 |
| Lindstrom, J | 1 |
| Conti-Fine, BM; Karachunski, PI; Okita, DK; Ostlie, NS | 3 |
| Drachman, DB; McIntosh, KR; Yang, B | 1 |
| Bai, XF; Huang, YM; Li, HL; Link, H; Shi, FD; Van der Meide, PH | 1 |
| Atassi, MZ; Deitiker, P; Oshima, M; Yokoi, T | 1 |
| Levi, M; Link, H; Shi, FD; Wahren, B; Xiao, BG; Yu, LY; Zhang, GX; Zhu, J | 1 |
| Conti-Fine, BM; David, CS; Karachunski, P; Raju, R; Sieck, GC; Zhan, WZ | 1 |
| Aarli, JA; Agius, MA; Aziz, T; Fairclough, RH; Kirvan, CA; Lin, MY; Oger, JJ; Schafer, AL; Zhu, S | 1 |
| Rimer, M | 1 |
| Conti-Fine, BM; Karachunski, PI; Lei, S; Lindstrom, JM; Okita, DK; Ostlie, NS | 1 |
| Barchan, D; Fuchs, S; Souroujon, MC | 1 |
| Agius, MA; Yuen, E | 1 |
| Adorini, L; Amadio, S; Brambilla, E; Comi, G; Galbiati, F; Grimaldi, LM; Martino, G; Moiola, L; Vincent, A | 1 |
| Balasa, B; Christadoss, P; Deng, C; Lee, J; Sarvetnick, N | 1 |
| Fredrikson, S; Link, H; Osterman, PO; Qiao, J; Wang, WZ | 1 |
| Chalkley, R; Corlett, L; Deshpande, S; Driscoll, PC; Jacobson, LW; Matsuo, H; Nagvekar, N; Spack, EG; Willcox, N | 1 |
| Hofmann, WW; Smith, ME | 1 |
| Miyahara, T; Nakaji, S; Oka, K | 1 |
| Bernard, I; Cautain, B; De Baets, M; Druet, P; Guéry, JC; Hoedemaekers, A; Martinez, K; Saoudi, A | 1 |
| Mamalaki, A; Tsantili, P; Tzartos, SJ | 1 |
| Eliopoulos, E; Liolitsas, C; Mamalaki, A; Papanastasiou, D; Poulas, K; Tzartos, SJ | 1 |
| Conti-Fine, BM; Garman, R; Karachunski, PI; Okita, DK; Ostlie, NS | 1 |
| Antozzi, C; Barchan, D; Fuchs, S; Im, SH; Souroujon, MC | 1 |
| Nicolle, MW; Wang, D | 1 |
| Conti-Fine, BM; Karachunski, PI; Monfardini, C; Ostlie, NS | 1 |
| Conti-Fine, BM; Karachunski, PI; Kronenberg, M; Monfardini, C; Ostlie, NS; Wang, W | 1 |
| Mozes, E; Paas-Rozner, M; Sela, M | 1 |
| Rícný, J; Simková, L; Vincent, A | 1 |
| Carmon, S; Fuchs, S; Souroujon, MC | 1 |
| Bellone, M; Conti-Tronconi, BM; Lei, S; Manfredi, AA; Ostlie, N | 1 |
| Gern, U; Lindstrom, J; Malcherek, G; Melms, A; Müller, CA; Schoepfer, R; Wiethölter, H | 1 |
| Remoundos, MS; Tzartos, SJ | 1 |
| Claudio, T; Loutrari, H; Tzartos, SJ | 1 |
| Aoyagi, T; Hayashi, K; Ishigaki, Y; Sato, T; Song, DL | 1 |
| Hamada, T; Okumura, S; Takamori, M | 1 |
| Bellone, M; Conti-Tronconi, BM; Lei, S; Ostlie, N | 1 |
| Chrestel, S; Hohlfeld, R; Schönbeck, S | 1 |
| Beeson, D; Harcourt, GC; Newsom-Davis, J; Sommer, N; Willcox, N | 1 |
| Cung, MT; Demange, P; Loutrari, H; Mamalaki, A; Marraud, M; Papadouli, I; Sakarellos, C; Tsikaris, V; Tzartos, SJ | 1 |
| De Baets, MH; Graus, YM; Tzartos, S; Van Breda Vriesman, PJ; Verschuuren, JJ | 1 |
| Itano, AA; McCallum, RM; Pachner, AR; Ricalton, NS | 1 |
| Choe, S; Itano, A; Pachner, AR; Ricalton, N | 1 |
| Komai, K; Okumura, S; Satake, R; Takamori, M | 1 |
| Conti-Tronconi, BM; Howard, JF; Manfredi, AA; Protti, MP; Straub, C | 1 |
| Ashizawa, T; Atassi, MZ; Oshima, M; Pollack, MS | 1 |
| Barkas, T; Frutiger, S; Hughes, GJ; Jeannet, M; Schluep, M; Steck, A; Zhang, Y | 1 |
| Anand, R; Conroy, WG; Lindstrom, J; Saedi, MS | 1 |
| Bertrams, J; Conti-Tronconi, B; Hohlfeld, R; Kalies, I; Toyka, KV | 1 |
| Conti-Tronconi, B; Heininger, K; Hohlfeld, R; Michels, M; Toyka, KV; Tzartos, SJ | 1 |
| Hoppe, F; Kirchner, T; Müller-Hermelink, HK; Schalke, B; Tzartos, S; Wekerle, H | 1 |
| Ballivet, M; Barkas, T; Chrestel, S; Mauron, A; Melms, A; Schalke, BC; Wekerle, H | 1 |
| Griesmann, GE; Lennon, VA | 1 |
| Beeson, D; Harcourt, G; Newsom-Davis, J; Rothbard, JB; Sommer, N; Willcox, N | 1 |
| Fisher, CA; Jermy, AC; Newsom-Davis, J; Vincent, AC; Willcox, NA | 1 |
| Carson, W; Conti-Tronconi, BM; Hohlfeld, R; Toyka, KV; Tzartos, SJ | 1 |
| Kantor, FS; Pachner, AR | 1 |
| Conti-Tronconi, BM; Fahsbender, A; Heininger, K; Hohlfeld, R; Michels, M; Tesch, H; Toyka, KV | 1 |
| Newsom-Davis, J; Schluep, M; Vincent, A; Whiting, PJ | 1 |
| Biesecker, G; Koffler, D | 1 |
| Asher, O; Fuchs, S; Neumann, D | 1 |
| Nagata, M; Okumura, S; Takamori, M; Yoshikawa, H | 1 |
| Fels, G; Maelicke, A; Sundaram, PV; Yang, BH | 1 |
| Cardinet, GH; Lindstrom, JM; Shelton, GD | 1 |
| Calvo, AM; DuPont, BL; Koethe, SM; McQuillen, MP; Otterson, G | 1 |
| Hochschwender, S; Lindstrom, J; Tzartos, S; Vasquez, P | 1 |
| Blair, DA; Koethe, S; Richman, DP; Taves, CJ | 1 |
| Cora, EM; Kessler, MJ; Martinez-Carrion, M; Toro-Goyco, E | 1 |
| Atassi, MZ; Griesmann, GE; Lambert, EH; Lennon, VA; McCormick, DJ | 1 |
| Herrmann, C; Keesey, JC; Lindstrom, JM; Mulder, DG | 1 |
| Efthimiadis, A; Sophianos, D; Tzartos, SJ | 1 |
| DuPont, BL; Koethe, SM; McQuillen, MP | 1 |
11 review(s) available for torpedo and Anti-MuSK Myasthenia Gravis
| Article | Year |
|---|---|
Immunisation with Torpedo acetylcholine receptor.
Topics: Adjuvants, Immunologic; Animals; Antibodies; Antibodies, Monoclonal; Autoimmune Diseases; Chemical Phenomena; Chemistry; Electrophysiology; Immunization; Immunoassay; Immunoglobulin Idiotypes; Immunosuppressive Agents; Mice; Mice, Inbred Strains; Motor Endplate; Muscles; Myasthenia Gravis; Neuromuscular Junction; Rabbits; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Nicotinic; Synaptic Transmission; Torpedo | 1984 |
[Effectiveness of neurotransmitters on receptor membranes. a. Acetylcholine receptors].
Topics: Action Potentials; Animals; Antibodies; Calmodulin; Mice; Myasthenia Gravis; Neurotransmitter Agents; Rats; Receptors, Cholinergic; Torpedo | 1984 |
Antiacetylcholine receptor antibodies and myasthenia gravis.
Topics: Animals; Antigen-Antibody Complex; Autoantibodies; Electric Organ; Epitopes; Humans; Muscles; Myasthenia Gravis; Receptors, Cholinergic; Torpedo | 1983 |
A role of alpha-fetoprotein in autoimmune diseases.
Topics: alpha-Fetoproteins; Animals; Antibody Formation; Autoimmune Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Lymphocyte Activation; Myasthenia Gravis; Myelin Basic Protein; Rabbits; Rats; Receptors, Cholinergic; Torpedo | 1983 |
Experimental myasthenia gravis: a model of receptor disease.
Topics: Animals; Bungarotoxins; Complement C3; Disease Models, Animal; Electric Organ; Electric Stimulation; Evoked Potentials; Humans; Immunity, Cellular; Immunoglobulin G; Models, Biological; Motor Endplate; Myasthenia Gravis; Rabbits; Receptors, Cholinergic; Synapses; Synaptic Transmission; Torpedo | 1980 |
[Acetylcholine receptor; structure and function (author's transl)].
Topics: Amino Acids; Animals; Antibodies; Humans; Molecular Weight; Myasthenia Gravis; Rats; Receptors, Cholinergic; Torpedo | 1981 |
Molecular recognition of acetylcholine receptor. Recognition by alpha-neurotoxins and by immune and autoimmune responses and manipulation of the responses.
Topics: Amino Acid Sequence; Animals; Autoantibodies; Binding Sites; Bungarotoxins; Cobra Neurotoxin Proteins; Epitopes; Erabutoxins; Humans; Immune Tolerance; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Sequence Data; Myasthenia Gravis; Neurotoxins; Peptide Fragments; Protein Binding; Receptors, Antigen, T-Cell; Receptors, Nicotinic; Structure-Activity Relationship; T-Lymphocytes; Torpedo | 1994 |
Nicotinic acetylcholine receptors in health and disease.
Topics: Acetylcholine; Alzheimer Disease; Anesthetics; Animals; Autoimmune Diseases; Cholinergic Agents; Cholinergic Antagonists; Epilepsy; Ethanol; Female; Keratinocytes; Male; Models, Molecular; Muscle Proteins; Myasthenia Gravis; Nerve Tissue Proteins; Neuromuscular Junction; Nicotine; Parkinson Disease; Pregnancy; Protein Conformation; Receptors, Nicotinic; Schizophrenia; Smoking; Torpedo; Tourette Syndrome | 1997 |
Myasthenia gravis: prototype of the antireceptor autoimmune diseases.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Autoantibodies; Autoimmune Diseases; Bungarotoxins; Combined Modality Therapy; Disease Models, Animal; Epitopes; Humans; Immunity, Cellular; Ion Channel Gating; Models, Biological; Myasthenia Gravis; Neuromuscular Junction; Rabbits; Receptors, Cholinergic; Receptors, Nicotinic; Structure-Activity Relationship; T-Lymphocytes, Cytotoxic; Thymus Gland; Torpedo | 1990 |
The main immunogenic region (MIR) of the nicotinic acetylcholine receptor and the anti-MIR antibodies.
Topics: Adult; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Autoantibodies; Autoimmune Diseases; Bungarotoxins; Disease Models, Animal; Epitopes; Female; Humans; Incidence; Infant, Newborn; Male; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Myasthenia Gravis; Peptide Fragments; Pregnancy; Protein Conformation; Receptors, Nicotinic; Torpedo | 1991 |
Myasthenia gravis--current concepts.
Topics: Acetylcholine; Adrenal Cortex Hormones; Adult; Animals; Autoantibodies; Autoimmune Diseases; Azathioprine; Electromyography; Electrophysiology; Female; Humans; Male; Myasthenia Gravis; Plasma Exchange; Rabbits; Receptors, Cholinergic; Thymectomy; Thymoma; Thymus Neoplasms; Torpedo | 1985 |
128 other study(ies) available for torpedo and Anti-MuSK Myasthenia Gravis
| Article | Year |
|---|---|
Structural characterization of the main immunogenic region of the Torpedo acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites, Antibody; Green Fluorescent Proteins; Humans; Molecular Sequence Data; Myasthenia Gravis; Peptide Fragments; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, Nicotinic; Recombinant Fusion Proteins; Sequence Analysis, Protein; Torpedo | 2014 |
Delivery of an miR155 inhibitor by anti-CD20 single-chain antibody into B cells reduces the acetylcholine receptor-specific autoantibodies and ameliorates experimental autoimmune myasthenia gravis.
Topics: Active Transport, Cell Nucleus; Animals; Antigens, CD20; Autoantibodies; B-Lymphocytes; Blotting, Western; Cell Nucleus; Female; Gene Expression; Gene Knockdown Techniques; Humans; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; MicroRNAs; Myasthenia Gravis; Myasthenia Gravis, Autoimmune, Experimental; NF-kappa B; Receptors, Cholinergic; Receptors, Interleukin-4; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Single-Chain Antibodies; Torpedo | 2014 |
Design, synthesis, and characterization of a 39 amino acid peptide mimic of the main immunogenic region of the Torpedo acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Affinity; Base Sequence; Binding Sites; Blotting, Western; Drug Design; Fish Proteins; Immune Sera; Models, Molecular; Molecular Mimicry; Molecular Sequence Data; Myasthenia Gravis; Peptides; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Cholinergic; Torpedo | 2014 |
Role of ubiquitin ligase Cbl-b in B-cell activation of dendritic cells loaded with Tα146-162 in the treatment of experimental autoimmune myasthenia gravis in mice.
Topics: Animals; B-Lymphocytes; Dendritic Cells; Disease Models, Animal; Intracellular Signaling Peptides and Proteins; Lymph Nodes; Male; Mice, Inbred C57BL; Myasthenia Gravis; Peptide Fragments; Phospholipase C gamma; Protein-Tyrosine Kinases; Receptors, Muscarinic; RNA, Messenger; Spleen; src-Family Kinases; Syk Kinase; Torpedo; Ubiquitin-Protein Ligases | 2014 |
Mannose-binding lectin pathway is not involved in myasthenia gravis pathogenesis.
Topics: Adult; Aged; Animals; Complement Pathway, Mannose-Binding Lectin; Female; Humans; Immunoglobulin G; Male; Mannose-Binding Lectin; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myasthenia Gravis; Receptors, Cholinergic; Signal Transduction; Torpedo | 2009 |
In vivo adsorption of autoantibodies in myasthenia gravis using Nanodisc-incorporated acetylcholine receptor.
Topics: Adsorption; Animals; Autoantibodies; Enzyme-Linked Immunosorbent Assay; Female; Mice; Muscle, Skeletal; Myasthenia Gravis; Receptors, Cholinergic; Tissue Scaffolds; Torpedo | 2010 |
Production and characterization of a T cell receptor transgenic mouse recognizing the immunodominant epitope of the Torpedo californica acetylcholine receptor.
Topics: Animals; Antibodies; Case-Control Studies; Disease Models, Animal; Flow Cytometry; Immunization; Immunodominant Epitopes; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myasthenia Gravis; Myasthenia Gravis, Autoimmune, Experimental; Peptides; Phenotype; Receptors, Antigen, T-Cell; Receptors, Cholinergic; Torpedo | 2003 |
Novel immunotoxin: a fusion protein consisting of gelonin and an acetylcholine receptor fragment as a potential immunotherapeutic agent for the treatment of Myasthenia gravis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Female; Genes, Synthetic; Humans; Immunotoxins; Models, Animal; Molecular Sequence Data; Myasthenia Gravis; Peptide Fragments; Plant Proteins; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Recombinant Fusion Proteins; Restriction Mapping; Ribosome Inactivating Proteins, Type 1; Torpedo | 2006 |
Differential diagnosis of various forms of myasthenia and endocrine ophthalmopathy by immunoblotting.
Topics: Adolescent; Adult; Animals; Autoantibodies; Diagnosis, Differential; Eye Diseases; Female; Humans; Immunoblotting; Male; Myasthenia Gravis; Receptors, Nicotinic; Thyroiditis, Autoimmune; Torpedo | 2005 |
Pros and cons of treating murine myasthenia gravis with anti-C1q antibody.
Topics: Animals; Antibodies; Antigen-Antibody Complex; B-Lymphocytes; Complement C1q; Complement C3; Complement System Proteins; Feasibility Studies; Immunoglobulin G; Interleukin-6; Kidney; Lymph Nodes; Mice; Mice, Inbred Strains; Myasthenia Gravis; Receptors, Cholinergic; Severity of Illness Index; T-Lymphocytes; Torpedo | 2007 |
The role of CD8+CD28 regulatory cells in suppressing myasthenia gravis-associated responses by a dual altered peptide ligand.
Topics: Animals; bcl-X Protein; Caspase 3; Caspase 8; CD28 Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Down-Regulation; Female; Forkhead Transcription Factors; Immunization; Interleukin-10; Interleukin-2 Receptor alpha Subunit; Ligands; Mice; Mice, Knockout; Myasthenia Gravis; Peptides; Receptors, Nicotinic; Torpedo; Transforming Growth Factor beta; Up-Regulation | 2007 |
Prevention of experimental autoimmune myasthenia gravis in rats by fetal alpha-fetoprotein-rich fractions.
Topics: Acute Disease; alpha-Fetoproteins; Animals; Antibody Formation; Autoantibodies; Chronic Disease; Electromyography; Female; Fetus; Humans; Immunity, Cellular; Immunosuppressive Agents; Lymphocyte Activation; Muscle Denervation; Muscles; Myasthenia Gravis; Radioimmunoassay; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1984 |
Immunosuppression of experimental autoimmune myasthenia gravis by alpha-fetoprotein rich formation.
Topics: alpha-Fetoproteins; Animals; Antibody Formation; Autoimmune Diseases; Immunosuppression Therapy; Myasthenia Gravis; Rabbits; Radioimmunoassay; Receptors, Cholinergic; Torpedo | 1981 |
Structure and function of the acetylcholine receptor molecule studied using monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites, Antibody; Electric Organ; Electrophorus; Epitopes; Humans; Molecular Weight; Muscles; Myasthenia Gravis; Rats; Receptors, Cholinergic; Torpedo | 1981 |
Anti-idiotypic route to anti-acetylcholine receptor antibodies and experimental myasthenia gravis.
Topics: Animals; Antibody Specificity; Autoantibodies; Electrophorus; Epitopes; Immunoglobulin Idiotypes; Myasthenia Gravis; Parasympathomimetics; Quaternary Ammonium Compounds; Rabbits; Receptors, Cholinergic; Torpedo | 1982 |
Physiochemical and immunological properties of acetylcholine receptors from human muscle.
Topics: Animals; Humans; Isoelectric Point; Mice; Molecular Weight; Muscle Denervation; Myasthenia Gravis; Protein Conformation; Rats; Receptors, Nicotinic; Species Specificity; Torpedo | 1984 |
Use of monoclonal antibodies to study acetylcholine receptors from electric organs, muscle, and brain and the autoimmune response to receptor in myasthenia gravis.
Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Autoimmune Diseases; Brain; Chickens; Electric Organ; Electrophorus; Humans; Muscles; Myasthenia Gravis; Organ Specificity; Receptors, Cholinergic; Species Specificity; Torpedo | 1983 |
Spectrotypic analysis of antibodies to acetylcholine receptors in experimental autoimmune myasthenia gravis.
Topics: Animals; Antibodies, Monoclonal; Antibody Diversity; Antibody Specificity; Autoantibodies; Autoimmune Diseases; Female; Isoelectric Focusing; Muscles; Myasthenia Gravis; Rats; Rats, Inbred BN; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1984 |
Penicillamine-induced myasthenia gravis: effects of penicillamine on acetylcholine receptor.
Topics: Acetylcholine; Animals; Binding Sites; Bungarotoxins; Myasthenia Gravis; Penicillamine; Receptors, Cholinergic; Torpedo | 1982 |
Structure of the acetylcholine receptor and specificities of antibodies to it in myasthenia gravis.
Topics: Animals; Antibody Specificity; Autoantibodies; Disease Models, Animal; Humans; Myasthenia Gravis; Receptors, Cholinergic; Torpedo | 1982 |
Factors in the production of experimental autoimmune myasthenia gravis in acetylcholine receptor immunized rabbits.
Topics: Animals; Antibodies; Autoimmune Diseases; Complement Fixation Tests; Complement System Proteins; Immunization; Male; Myasthenia Gravis; Rabbits; Receptors, Cholinergic; Torpedo | 1981 |
Factors affecting the susceptibility of different strains of mice to experimental myasthenia gravis.
Topics: Animals; Antibodies; Disease Susceptibility; Electromyography; H-2 Antigens; Immunization; Mice; Mice, Inbred Strains; Myasthenia Gravis; Receptors, Cholinergic; Torpedo | 1981 |
Freeze-fracture, labelled-replica, and electrophysiological studies of junctional fold destruction in myasthenia gravis and experimental autoimmune myasthenia gravis.
Topics: Adult; Animals; Autoimmune Diseases; Female; Freeze Fracturing; Humans; Immunoglobulin G; Intercostal Muscles; Male; Membrane Potentials; Middle Aged; Myasthenia Gravis; Neuromuscular Junction; Rabbits; Rats; Receptors, Cholinergic; Torpedo | 1981 |
Studies on the pathophysiology of chronic D-penicillamine-induced myasthenia.
Topics: Animals; Antibodies; Binding, Competitive; Bungarotoxins; Female; Guinea Pigs; Lymphocyte Activation; Myasthenia Gravis; Penicillamine; Receptors, Cholinergic; Torpedo | 1981 |
Lymphocyte activation in experimental autoimmune myasthenia gravis.
Topics: Animals; Antibody Formation; Antibody Specificity; Autoimmune Diseases; Cross Reactions; Dose-Response Relationship, Immunologic; Female; Lymphocyte Activation; Myasthenia Gravis; Rats; Rats, Inbred Lew; Receptors, Cholinergic; T-Lymphocytes; Torpedo | 1982 |
Effect of anti-acetylcholine receptor Fab fragments from goats on functional membrane-bound receptor.
Topics: Animals; Bungarotoxins; Cell Membrane Permeability; Electric Organ; Goats; Immunoglobulin Fab Fragments; Models, Molecular; Myasthenia Gravis; Receptors, Cholinergic; Sodium; Torpedo | 1982 |
Binding of myasthenia gravis antibodies to different acetylcholine receptor preparations.
Topics: Animals; Autoantibodies; Humans; Myasthenia Gravis; Rats; Receptors, Cholinergic; Species Specificity; Torpedo | 1982 |
Lack of inter-animal cross-reaction of anti-acetylcholine receptor antibodies at the receptor-binding site as demonstrated by heterologous anti-idiotype antisera: implications for immunotherapy of myasthenia gravis.
Topics: Animals; Antibodies; Cross Reactions; Immune Sera; Immunoglobulin G; Immunoglobulin Idiotypes; Mice; Myasthenia Gravis; Rabbits; Receptors, Cholinergic; Sheep; Species Specificity; Torpedo | 1982 |
Experimental myasthenia gravis is inhibited by receptor-antireceptor complexes.
Topics: Animals; Antibody Formation; Antigen-Antibody Complex; Chromatography, Gel; Disease Models, Animal; Female; Fish Venoms; Mice; Molecular Weight; Myasthenia Gravis; Rabbits; Receptors, Cholinergic; Receptors, Nicotinic; Torpedo | 1982 |
A monoclonal anti-idiotypic antibody against anti-receptor antibodies from myasthenic sera.
Topics: Animals; Antibodies, Monoclonal; Cross Reactions; Humans; Immunoglobulin G; Immunoglobulin Idiotypes; Myasthenia Gravis; Receptors, Cholinergic; Torpedo | 1982 |
[Experimental rabbit model of myasthenia gravis produced with acetylcholine receptor of nicotinic type from the "generating organ" of electric ray (author's transl)].
Topics: Animals; Autoimmune Diseases; Disease Models, Animal; Electric Organ; Electromyography; Female; Myasthenia Gravis; Rabbits; Receptors, Cholinergic; Receptors, Nicotinic; Torpedo | 1981 |
Production and assay of antibodies to acetylcholine receptors.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Bungarotoxins; Cell Fusion; Electric Organ; Iodine Radioisotopes; Muscles; Myasthenia Gravis; Rats; Receptors, Cholinergic; Torpedo | 1981 |
Profile of the regions of acetylcholine receptor alpha chain recognized by T-lymphocytes and by antibodies in EAMG-susceptible and non-susceptible mouse strains after different periods of immunization with the receptor.
Topics: Amino Acid Sequence; Animals; Antibodies; Disease Models, Animal; Epitopes; Female; Immunization; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Sequence Data; Myasthenia Gravis; Receptors, Cholinergic; T-Lymphocytes; Time Factors; Torpedo | 1994 |
Suppression of experimental autoimmune myasthenia gravis by nasal administration of acetylcholine receptor.
Topics: Administration, Intranasal; Animals; Concanavalin A; Electric Organ; Enzyme-Linked Immunosorbent Assay; Female; Hypersensitivity, Delayed; Immunoglobulin G; Interferon-gamma; Lymphocyte Activation; Myasthenia Gravis; Myelin Basic Protein; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Time Factors; Torpedo | 1995 |
B cell responses to acetylcholine receptor in rats orally tolerized against experimental autoimmune myasthenia gravis.
Topics: Administration, Oral; Animals; Antibody Affinity; Autoantibodies; Autoimmune Diseases; B-Lymphocytes; Buffers; Encephalomyelitis, Autoimmune, Experimental; Female; Freund's Adjuvant; Immune Tolerance; Immunization; Immunoglobulin G; Lymph Nodes; Lymphoid Tissue; Myasthenia Gravis; Myelin Basic Protein; Pharmaceutical Vehicles; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Thymus Gland; Torpedo | 1995 |
Three-dimensional location of the main immunogenic region of the acetylcholine receptor.
Topics: Animals; Antibody Specificity; Antigen-Antibody Reactions; Autoantibodies; Autoantigens; Autoimmune Diseases; Binding Sites; Epitopes; Humans; Image Processing, Computer-Assisted; Immunoglobulin Fab Fragments; Microscopy, Electron; Models, Molecular; Myasthenia Gravis; Protein Conformation; Protein Structure, Tertiary; Receptors, Nicotinic; Torpedo | 1995 |
Mechanisms by which the I-ABM12 mutation influences susceptibility to experimental myasthenia gravis: a study in homozygous and heterozygous mice.
Topics: Animals; Antigen Presentation; CD4-Positive T-Lymphocytes; Haplotypes; Heterozygote; Histocompatibility Antigens Class II; Homozygote; Mice; Mice, Inbred C57BL; Mutation; Myasthenia Gravis; Receptors, Cholinergic; Torpedo | 1995 |
Leflunomide prevents the development of experimentally induced myasthenia gravis.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Female; Flow Cytometry; Immunization; Immunosuppressive Agents; Isoxazoles; Leflunomide; Myasthenia Gravis; Rats; Rats, Inbred Strains; Receptors, Cholinergic; T-Lymphocyte Subsets; Thymus Gland; Time Factors; Torpedo | 1995 |
T-helper epitopes on human nicotinic acetylcholine receptor in myasthenia gravis.
Topics: Adult; Aged; Amino Acid Sequence; Animals; Antibody Specificity; Autoantibodies; CD4-Positive T-Lymphocytes; Cell Line; Epitopes; Female; Humans; Lymphocyte Activation; Male; Middle Aged; Molecular Sequence Data; Muscles; Myasthenia Gravis; Peptides; Receptors, Nicotinic; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Thymus Gland; Time Factors; Torpedo | 1993 |
In vivo preferential usage of TCR V beta 8 in Torpedo acetylcholine receptor immune response in the murine experimental model of myasthenia gravis.
Topics: Animals; Antibodies, Monoclonal; Cell Division; Immunity, Cellular; Lymph Nodes; Male; Mice; Mice, Inbred C57BL; Myasthenia Gravis; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Cholinergic; Torpedo | 1995 |
Depletion of CD8+ T cells suppresses the development of experimental autoimmune myasthenia gravis in Lewis rats.
Topics: Animals; Antibodies, Monoclonal; Autoimmune Diseases; CD8-Positive T-Lymphocytes; Female; Hypersensitivity, Delayed; Immune Tolerance; Immunization; Immunoglobulin G; Interferon-gamma; Lymphocyte Activation; Lymphocyte Count; Lymphoid Tissue; Muscles; Myasthenia Gravis; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Th1 Cells; Torpedo | 1995 |
Use of complementary peptides and their antibodies in B-cell-mediated autoimmune disease: prevention of experimental autoimmune myasthenia gravis with a peptide vaccine.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; B-Lymphocytes; Base Sequence; Enzyme-Linked Immunosorbent Assay; Female; Molecular Sequence Data; Myasthenia Gravis; Peptides; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo; Vaccines, Synthetic | 1994 |
Thymus changes in experimentally induced myasthenia gravis.
Topics: Animals; Antibodies, Monoclonal; Bordetella pertussis; CD4-Positive T-Lymphocytes; Cells, Cultured; Female; Flow Cytometry; Myasthenia Gravis; Rats; Rats, Inbred Strains; Receptors, Cholinergic; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Thymus Gland; Torpedo | 1993 |
Suppression of experimental autoimmune myasthenia gravis by epitope-specific neonatal tolerance.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Autoantibodies; Autoimmune Diseases; Disease Susceptibility; Female; Gene Conversion; Genetic Predisposition to Disease; Histocompatibility Antigens Class II; Humans; Immune Tolerance; Immunization; Immunodominant Epitopes; Immunosuppression Therapy; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Myasthenia Gravis; Peptide Fragments; Receptors, Nicotinic; Single-Blind Method; Species Specificity; T-Lymphocytes, Helper-Inducer; Torpedo | 1994 |
Highly conserved TCR beta chain CDR3 sequences among immunodominant acetylcholine receptor-reactive T cells in murine myasthenia gravis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Conserved Sequence; Disease Models, Animal; DNA; Genes, Immunoglobulin; Immunodominant Epitopes; Immunoglobulin Variable Region; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Sequence Data; Myasthenia Gravis; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Cholinergic; T-Lymphocytes; Torpedo | 1994 |
T cell receptor V beta 15 dominates the antiacetylcholine receptor response in Lewis rat T cell lines.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Disease Models, Animal; DNA; Gene Expression; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Humans; Immunization; Molecular Sequence Data; Myasthenia Gravis; Rats; Rats, Inbred Lew; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Cholinergic; T-Lymphocytes; Torpedo | 1994 |
A disease-related epitope of Torpedo acetylcholine receptor. Residues involved in I-Ab binding, self-nonself discrimination, and TCR antagonism.
Topics: Amino Acid Sequence; Animals; Autoimmunity; Binding Sites; Binding, Competitive; Disease Models, Animal; Histocompatibility Antigens Class II; Immunization; Immunodominant Epitopes; Immunotherapy; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Myasthenia Gravis; Peptides; Receptors, Antigen, T-Cell; Receptors, Cholinergic; Sequence Homology, Amino Acid; T-Lymphocytes; Torpedo | 1994 |
beta-Bungarotoxin binding protein is immunogenic but lacks myasthenogenicity in rats.
Topics: Animals; Antibodies; Bungarotoxins; Carrier Proteins; Enzyme-Linked Immunosorbent Assay; Female; Immunoglobulin G; Myasthenia Gravis; Rats; Receptors, Cholinergic; Torpedo | 1994 |
B cell autoimmunity to acetylcholine receptor and its subunits in Lewis rats over the course of experimental autoimmune myasthenia gravis.
Topics: Animals; Antibodies; Autoimmune Diseases; Autoimmunity; B-Lymphocytes; Female; Immunoglobulin G; Lymphoid Tissue; Myasthenia Gravis; Radioimmunoassay; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1993 |
Stereo view of conformation and myasthenogenicity in synthetic peptides of acetylcholine receptor alpha-subunit.
Topics: Amino Acid Sequence; Animals; Autoantigens; Molecular Sequence Data; Myasthenia Gravis; Peptides; Protein Conformation; Rats; Rats, Inbred Lew; Receptors, Nicotinic; Torpedo | 1993 |
Approaches for studying the pathogenic T cells in autoimmune patients.
Topics: Amino Acid Sequence; Animals; Autoantigens; Cell Line; Humans; Molecular Sequence Data; Myasthenia Gravis; Receptors, Nicotinic; T-Lymphocytes; Thymoma; Torpedo | 1993 |
Induction of experimental autoimmune myasthenia gravis with acetylcholine receptors using a nonionic block copolymer as adjuvant.
Topics: Adjuvants, Immunologic; Animals; Antigen-Antibody Complex; Autoantibodies; Autoantigens; Autoimmune Diseases; Emulsions; Immunization; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; Myasthenia Gravis; Neostigmine; Receptors, Cholinergic; Torpedo | 1993 |
Prevention of experimental autoimmune myasthenia gravis by manipulation of the immune network with a complementary peptide for the acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Autoimmune Diseases; Electric Organ; Female; Molecular Sequence Data; Myasthenia Gravis; Peptide Fragments; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1993 |
Detection and characterization of blocking-type anti-acetylcholine receptor antibodies in sera from patients with myasthenia gravis.
Topics: Amino Acid Sequence; Animals; Autoantibodies; Binding Sites; Bungarotoxins; Humans; Molecular Sequence Data; Myasthenia Gravis; Peptides; Radioimmunoassay; Receptors, Cholinergic; Thymoma; Thymus Neoplasms; Torpedo | 1993 |
VH gene family utilization of anti-acetylcholine receptor antibodies in experimental autoimmune myasthenia gravis.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Autoantibodies; Autoimmune Diseases; Genes, Immunoglobulin; Immunoglobulin Heavy Chains; Immunoglobulin Idiotypes; Immunoglobulin Variable Region; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myasthenia Gravis; Receptors, Cholinergic; Species Specificity; Torpedo | 1993 |
Myasthenia gravis: effect on antibody binding of conservative substitutions of amino acid residues forming the main immunogenic region of the nicotinic acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Autoantibodies; Conserved Sequence; Humans; Molecular Sequence Data; Myasthenia Gravis; Osmolar Concentration; Peptide Fragments; Receptors, Nicotinic; Structure-Activity Relationship; Torpedo | 1993 |
Suppression of experimental autoimmune myasthenia gravis by oral administration of acetylcholine receptor.
Topics: Administration, Oral; Animals; Autoantibodies; Female; Immune Tolerance; Immunization; Myasthenia Gravis; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1993 |
B-cell activation in vitro by helper T cells specific to region alpha 146-162 of Torpedo californica nicotinic acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Antibody Formation; Antibody Specificity; Autoimmune Diseases; B-Lymphocytes; Cell Differentiation; Cell Line; Coculture Techniques; Cross Reactions; Culture Media, Conditioned; Epitopes; Female; Immunization; Interleukin-2; Interleukin-4; Lymphocyte Cooperation; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Myasthenia Gravis; Peptide Fragments; Plasma Cells; Receptors, Nicotinic; Sequence Alignment; Species Specificity; Th2 Cells; Torpedo | 1996 |
Evidence against chronic antigen-specific T lymphocyte activation in myasthenia gravis.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antibody Specificity; Chronic Disease; Clone Cells; Female; Flow Cytometry; Humans; Lymphocyte Activation; Male; Membrane Proteins; Middle Aged; Mutation; Myasthenia Gravis; Protein Structure, Tertiary; Receptors, Cholinergic; Receptors, Interleukin-2; Recombinant Proteins; Solubility; T-Lymphocytes; Torpedo | 1996 |
Prevention of experimental myasthenia gravis by nasal administration of synthetic acetylcholine receptor T epitope sequences.
Topics: Administration, Intranasal; Animals; Antibodies; CD4-Positive T-Lymphocytes; Diphtheria Toxin; Disease Models, Animal; Epitopes, T-Lymphocyte; Humans; Immunization; Interleukin-2; Mice; Mice, Inbred C57BL; Myasthenia Gravis; Peptides; Receptors, Cholinergic; Respiratory System; Spleen; Th2 Cells; Torpedo; Vaccines, Synthetic | 1997 |
How subtle differences in MHC class II affect the severity of experimental myasthenia gravis.
Topics: Animals; Antibody Specificity; Antigen Presentation; Autoantibodies; Autoimmune Diseases; DNA, Complementary; Female; Gene Rearrangement, T-Lymphocyte; Histocompatibility Antigens Class II; Hybridomas; Immunoglobulin G; Mice; Mice, Inbred C57BL; Myasthenia Gravis; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Cholinergic; Species Specificity; Torpedo | 1998 |
Nasal tolerance in experimental autoimmune myasthenia gravis (EAMG): induction of protective tolerance in primed animals.
Topics: Administration, Intranasal; Animals; Antibody Specificity; Cytokines; Disease Models, Animal; Female; Freund's Adjuvant; Immune Tolerance; Immunoglobulin G; Immunoglobulin Isotypes; Lymphocyte Activation; Myasthenia Gravis; Rats; Rats, Inbred Lew; Receptors, Cholinergic; RNA, Messenger; T-Lymphocytes; Th1 Cells; Th2 Cells; Torpedo | 1998 |
T cell responses in EAMG-susceptible and non-susceptible mouse strains after immunization with overlapping peptides encompassing the extracellular part of Torpedo californica acetylcholine receptor alpha chain. Implication to role in myasthenia gravis of
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Autoantibodies; Autoimmunity; Immunization; Mice; Mice, Inbred Strains; Molecular Sequence Data; Myasthenia Gravis; Peptide Fragments; Receptors, Cholinergic; T-Lymphocytes; Torpedo | 1998 |
Synthetic peptides fail to induce nasal tolerance to experimental autoimmune myasthenia gravis.
Topics: Animals; Antibodies; Female; Immune Tolerance; Immunoglobulin G; Muscles; Myasthenia Gravis; Nasal Cavity; Peptide Fragments; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1998 |
Susceptibility of HLA DR3 transgenic mice to experimental autoimmune myasthenia gravis.
Topics: Animals; Autoantibodies; Disease Susceptibility; Electric Organ; HLA-DR3 Antigen; Humans; Mice; Mice, Transgenic; Myasthenia Gravis; Neuromuscular Junction; Receptors, Cholinergic; Torpedo | 1998 |
Rapsyn antibodies in myasthenia gravis.
Topics: Animals; Autoantibodies; Cell Membrane; Chorea; Electric Organ; Female; Humans; Muscle Proteins; Myasthenia Gravis; Myotonia; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Receptors, Nicotinic; Reference Values; Synapses; Tissue Extracts; Torpedo | 1998 |
Agrin-induced aggregation of acetylcholine receptors in muscles of rats with experimental autoimmune myasthenia gravis.
Topics: Agrin; Animals; Electric Organ; Female; Muscle Denervation; Muscle, Skeletal; Myasthenia Gravis; Nerve Fibers; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1998 |
Immunization of bm12 mice with high doses of acetylcholine receptor overcomes their resistance to experimental autoimmune myasthenia gravis.
Topics: Animals; Immunity, Innate; Macromolecular Substances; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle, Skeletal; Myasthenia Gravis; Peptide Fragments; Receptors, Cholinergic; Torpedo | 1998 |
Nasal administration of synthetic acetylcholine receptor T epitopes affects the immune response to the acetylcholine receptor and prevents experimental myasthenia gravis.
Topics: Administration, Intranasal; Animals; CD4-Positive T-Lymphocytes; Epitopes; Immunosuppression Therapy; Mice; Mice, Inbred C57BL; Myasthenia Gravis; Peptide Fragments; Receptors, Cholinergic; Torpedo | 1998 |
Modulation of experimental autoimmune myasthenia gravis by recombinant fragments of the human acetylcholine receptor.
Topics: Animals; Antibodies, Monoclonal; Humans; Immunization, Passive; Lymphocyte Activation; Myasthenia Gravis; Peptide Fragments; Rats; Receptors, Cholinergic; Recombinant Proteins; T-Lymphocytes; Torpedo | 1998 |
Effect of anti-idiotopic antibody on the course of experimental autoimmune myasthenia gravis.
Topics: Animals; Antibodies, Anti-Idiotypic; Drug Administration Schedule; Female; Muscle, Skeletal; Myasthenia Gravis; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1998 |
IL-12 is involved in the induction of experimental autoimmune myasthenia gravis, an antibody-mediated disease.
Topics: Animals; Disease Models, Animal; Electromyography; Female; Humans; Immunoglobulin G; Interferon-gamma; Interleukin-12; Male; Mice; Mice, Inbred C57BL; Myasthenia Gravis; Neuromuscular Junction; Receptors, Cholinergic; Th1 Cells; Torpedo | 1998 |
The Th2 cytokine IL-4 is not required for the progression of antibody-dependent autoimmune myasthenia gravis.
Topics: Amino Acid Sequence; Animals; Autoantibodies; Cytokines; Disease Progression; Gene Deletion; Immunization; Immunodominant Epitopes; Immunoglobulin G; Interleukin-4; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Myasthenia Gravis; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Nicotinic; T-Lymphocyte Subsets; Th2 Cells; Torpedo | 1998 |
The B-cell repertoire in myasthenia gravis includes all four acetylcholine receptor subunits.
Topics: Adult; Aged; Aged, 80 and over; Animals; B-Lymphocytes; Cell Count; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Leukocytes, Mononuclear; Male; Middle Aged; Myasthenia Gravis; Receptors, Cholinergic; Torpedo | 1998 |
Scanning a DRB3*0101 (DR52a)-restricted epitope cross-presented by DR3: overlapping natural and artificial determinants in the human acetylcholine receptor.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Animals; Antigen Presentation; Cell Line; Epitopes, B-Lymphocyte; Epitopes, T-Lymphocyte; HLA-DR Antigens; Humans; Mice; Molecular Sequence Data; Myasthenia Gravis; Peptides; Protein Binding; Receptors, Cholinergic; Torpedo | 1999 |
Inhibition of autoreactive antibody effects with antibody feedings: a pilot study.
Topics: Administration, Oral; Animals; Autoantibodies; Cross Reactions; Electrophysiology; Female; gamma-Globulins; Humans; Immune Tolerance; Immunization; Intestinal Absorption; Myasthenia Gravis; Myenteric Plexus; Pilot Projects; Plasmapheresis; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1999 |
Specific immunoadsorbent for myasthenia gravis treatment: development of synthetic peptide designed to remove antiacetylcholine receptor antibody.
Topics: Acetylcholine; Animals; Binding Sites, Antibody; Cellulose; Humans; Immunoglobulin G; Immunosorbents; Ligands; Myasthenia Gravis; Peptide Fragments; Receptors, Cholinergic; Serum Albumin; Torpedo | 1998 |
Interleukin-4 deficiency facilitates development of experimental myasthenia gravis and precludes its prevention by nasal administration of CD4+ epitope sequences of the acetylcholine receptor.
Topics: Administration, Intranasal; Animals; Autoantibodies; Autoimmune Diseases; Bungarotoxins; CD4 Antigens; CD8 Antigens; Complement System Proteins; Epitopes; Immunoglobulin G; Interleukin-4; Mice; Mice, Knockout; Mutagenesis; Myasthenia Gravis; Neuromuscular Junction; Receptors, Cholinergic; Spleen; Th1 Cells; Th2 Cells; Torpedo | 1999 |
Experimental autoimmune myasthenia gravis may occur in the context of a polarized Th1- or Th2-type immune response in rats.
Topics: Animals; Antibodies, Monoclonal; Female; Genetic Predisposition to Disease; Immunophenotyping; Incidence; Injections, Intraperitoneal; Interferon-gamma; Lymphocyte Activation; Male; Myasthenia Gravis; Rats; Rats, Inbred BN; Rats, Inbred Lew; Receptors, Cholinergic; Th1 Cells; Th2 Cells; Torpedo | 1999 |
High affinity single-chain Fv antibody fragments protecting the human nicotinic acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Autoantibodies; Base Sequence; Binding, Competitive; DNA Primers; Humans; Hybridomas; Immunoglobulin Fragments; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Molecular Sequence Data; Multiple Myeloma; Muscle, Skeletal; Myasthenia Gravis; Rats; Rats, Inbred Lew; Receptors, Nicotinic; Recombinant Proteins; Spleen; Torpedo; Transcription, Genetic | 1999 |
Construction and characterization of a humanized single chain Fv antibody fragment against the main immunogenic region of the acetylcholine receptor.
Topics: Animals; Antibodies, Monoclonal; Base Sequence; Binding, Competitive; DNA Primers; Epitopes; Gene Expression; Humans; Hybridomas; Immunoglobulin Fragments; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Models, Molecular; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis; Myasthenia Gravis; Polymerase Chain Reaction; Protein Structure, Secondary; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Sequence Homology, Amino Acid; Torpedo | 1999 |
Subcutaneous administration of T-epitope sequences of the acetylcholine receptor prevents experimental myasthenia gravis.
Topics: Animals; Autoantibodies; CD4-Positive T-Lymphocytes; Cell Division; Disease Models, Animal; Epitopes; Immune Tolerance; Immunization; Injections, Subcutaneous; Mice; Mice, Inbred Strains; Myasthenia Gravis; Peptide Fragments; Receptors, Cholinergic; Solubility; Th2 Cells; Torpedo | 1999 |
Antigen-specific modulation of experimental myasthenia gravis: nasal tolerization with recombinant fragments of the human acetylcholine receptor alpha-subunit.
Topics: Administration, Intranasal; Animals; Disease Models, Animal; Electric Organ; Female; Humans; Immune Tolerance; Immunoglobulin G; Immunoglobulin Isotypes; Interleukin-2; Lymph Nodes; Lymphocyte Activation; Macromolecular Substances; Myasthenia Gravis; Mycobacterium tuberculosis; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Recombinant Proteins; Torpedo | 1999 |
Generation of acetylcholine receptor-specific human T cell lines using heterobifunctional antibody-targeted antigen presentation.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Bispecific; Antigen Presentation; Autoantigens; Autoimmune Diseases; Autoimmunity; B-Lymphocyte Subsets; CD4-Positive T-Lymphocytes; Cell Line, Transformed; Clone Cells; Herpesvirus 4, Human; Humans; Hybridomas; Immunoglobulin M; Isoantibodies; Myasthenia Gravis; Rats; Receptors, Antigen, B-Cell; Receptors, Cholinergic; T-Lymphocyte Subsets; Thymectomy; Thymoma; Thymus Neoplasms; Torpedo | 1999 |
Absence of IFN-gamma or IL-12 has different effects on experimental myasthenia gravis in C57BL/6 mice.
Topics: Animals; Autoantibodies; Binding Sites, Antibody; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Complement System Proteins; Cytokines; Epitopes, T-Lymphocyte; Genetic Predisposition to Disease; Immunity, Innate; Immunoglobulin G; Interferon-gamma; Interleukin-12; Lymphocyte Depletion; Mice; Mice, Inbred C57BL; Mice, Knockout; Myasthenia Gravis; Neuromuscular Junction; Receptors, Cholinergic; Spleen; Th1 Cells; Torpedo | 2000 |
Transgenic expression of IL-10 in T cells facilitates development of experimental myasthenia gravis.
Topics: Animals; Autoantibodies; CD4-Positive T-Lymphocytes; Cells, Cultured; Complement System Proteins; Cytokines; Epitopes, T-Lymphocyte; Female; Genetic Predisposition to Disease; Immunoglobulin G; Injections, Subcutaneous; Interleukin-10; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Myasthenia Gravis; Neuromuscular Junction; Receptors, Cholinergic; T-Lymphocytes; Torpedo | 2001 |
The nature of the active suppression of responses associated with experimental autoimmune myasthenia gravis by a dual altered peptide ligand administered by different routes.
Topics: Amino Acid Sequence; Animals; Cytokines; Female; Immunization; Interleukin-2; Interleukin-4; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Myasthenia Gravis; Peptide Fragments; Receptors, Cholinergic; T-Lymphocytes; Torpedo; Transforming Growth Factor beta | 2001 |
Determination of anti-acetylcholine receptor antibodies in myasthenic patients by use of time-resolved fluorescence.
Topics: Adult; Aged; Aged, 80 and over; Animals; Autoantibodies; Chromatography, High Pressure Liquid; Cobra Neurotoxin Proteins; Electric Organ; Europium; Female; Fluoroimmunoassay; Humans; Male; Middle Aged; Myasthenia Gravis; Receptors, Nicotinic; Sensitivity and Specificity; Torpedo; Tumor Cells, Cultured | 2002 |
Modulation of anti-acetylcholine receptor antibody specificities and of experimental autoimmune myasthenia gravis by synthetic peptides.
Topics: Amino Acid Sequence; Animals; Antibody Formation; Antibody Specificity; Disease Models, Animal; Epitopes; Immunization, Passive; Molecular Sequence Data; Myasthenia Gravis; Peptide Fragments; Radioimmunoassay; Receptors, Cholinergic; Torpedo | 1992 |
T helper function of CD4+ cells specific for defined epitopes on the acetylcholine receptor in congenic mouse strains.
Topics: Animals; Antibody Formation; B-Lymphocytes; CD4-Positive T-Lymphocytes; Epitopes; Female; H-2 Antigens; Haplotypes; Immunophenotyping; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myasthenia Gravis; Oligopeptides; Receptors, Cholinergic; T-Lymphocytes, Helper-Inducer; Torpedo | 1992 |
T cells from normal and myasthenic individuals recognize the human acetylcholine receptor: heterogeneity of antigenic sites on the alpha-subunit.
Topics: Animals; Autoantigens; Autoimmune Diseases; CD4-Positive T-Lymphocytes; Cells, Cultured; Cross Reactions; DNA; Epitopes; HLA-DR Antigens; Immune Tolerance; Lymphocyte Activation; Myasthenia Gravis; Peptide Fragments; Receptors, Cholinergic; Recombinant Fusion Proteins; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Torpedo | 1992 |
Precise epitope mapping of monoclonal antibodies to the cytoplasmic side of the acetylcholine receptor alpha subunit. Dissecting a potentially myasthenogenic epitope.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites, Antibody; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Epitopes; Molecular Sequence Data; Myasthenia Gravis; Rats; Receptors, Cholinergic; Torpedo | 1992 |
Use of Torpedo-mouse hybrid acetylcholine receptors reveals immunodominance of the alpha subunit in myasthenia gravis antisera.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Epitopes; Fibroblasts; Hybridization, Genetic; Immune Sera; Mice; Myasthenia Gravis; Receptors, Cholinergic; Temperature; Torpedo | 1992 |
Suppression of experimental autoimmune myasthenia gravis with new immunosuppressants: 15-deoxyspergualin and actinobolin.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antibody Formation; Benzopyrans; Electric Organ; Female; Guanidines; Immunosuppressive Agents; Microscopy, Immunoelectron; Myasthenia Gravis; Neuromuscular Junction; Pyrans; Rats; Receptors, Cholinergic; Torpedo | 1992 |
Myasthenogenicity in the main immunogenic region of acetylcholine receptor as modified by conformational design: an approach to antigenic synthetic peptides.
Topics: Amino Acid Sequence; Animals; Electrophysiology; Female; Molecular Sequence Data; Motor Endplate; Muscle Denervation; Myasthenia Gravis; Peptides; Protein Conformation; Rats; Receptors, Cholinergic; Torpedo | 1992 |
Experimental myasthenia gravis in congenic mice. Sequence mapping and H-2 restriction of T helper epitopes on the alpha subunits of Torpedo californica and murine acetylcholine receptors.
Topics: Amino Acid Sequence; Animals; Autoimmune Diseases; CD4-Positive T-Lymphocytes; Cross Reactions; H-2 Antigens; Lymphocyte Activation; Mice; Mice, Inbred Strains; Molecular Sequence Data; Myasthenia Gravis; Peptides; Receptors, Nicotinic; Sequence Alignment; Structure-Activity Relationship; Time Factors; Torpedo | 1991 |
Acetylcholine receptor-reactive T lymphocytes from healthy subjects and myasthenia gravis patients.
Topics: Animals; Cell Division; Cell Line; Epitopes; HLA Antigens; Humans; Myasthenia Gravis; Phenotype; Receptors, Cholinergic; Recombinant Proteins; Reference Values; T-Lymphocytes; Time Factors; Torpedo | 1991 |
In vivo effects of neonatal administration of antiidiotype antibodies on experimental autoimmune myasthenia gravis.
Topics: Animals; Animals, Newborn; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Disease Models, Animal; Female; Fishes; Immunoglobulin Idiotypes; Myasthenia Gravis; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1991 |
Anti-ligand antibodies as potential autoantigens: in vitro and in vivo characteristics of anti-bungarotoxin antibodies in the idiotype network.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antibodies; Antibodies, Anti-Idiotypic; Autoantigens; Binding Sites, Antibody; Bungarotoxins; Immunoglobulin Idiotypes; Ligands; Mice; Molecular Structure; Myasthenia Gravis; Neutralization Tests; Receptors, Cholinergic; Receptors, Nicotinic; Torpedo; Tumor Cells, Cultured | 1991 |
Chronic murine experimental myasthenia gravis: strength testing and serology.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Chronic Disease; Exercise Test; Female; Immunization; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myasthenia Gravis; Receptors, Cholinergic; Serum Albumin, Bovine; Torpedo | 1991 |
Conformational modification enhances myasthenogenicity in synthetic peptide of acetylcholine receptor alpha-subunit.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Sequence; Animals; Autoimmune Diseases; Bungarotoxins; Female; Immunization; Molecular Sequence Data; Myasthenia Gravis; Peptide Fragments; Protein Conformation; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Receptors, Nicotinic; Structure-Activity Relationship; Torpedo | 1990 |
Immunodominant regions for T helper-cell sensitization on the human nicotinic receptor alpha subunit in myasthenia gravis.
Topics: Amino Acid Sequence; Animals; CD4 Antigens; Cell Line; Haplotypes; HLA-DR Antigens; Humans; Immunodominant Epitopes; Macromolecular Substances; Molecular Sequence Data; Myasthenia Gravis; Peptides; Receptors, Nicotinic; T-Lymphocytes, Helper-Inducer; Torpedo | 1990 |
Autoimmune T cell recognition of human acetylcholine receptor: the sites of T cell recognition in myasthenia gravis on the extracellular part of the alpha subunit.
Topics: Animals; Autoimmune Diseases; Cell Line; Dose-Response Relationship, Immunologic; HLA Antigens; Humans; Myasthenia Gravis; Oligopeptides; Peptide Fragments; Receptors, Nicotinic; T-Lymphocytes; Torpedo | 1990 |
Immunological heterogeneity of autoreactive T lymphocytes against the nicotinic acetylcholine receptor in myasthenic patients.
Topics: Animals; Cells, Cultured; HLA Antigens; Humans; Lymphocyte Activation; Mice; Myasthenia Gravis; Peptide Fragments; Receptors, Nicotinic; Recombinant Proteins; Species Specificity; T-Lymphocytes; Thymus Gland; Torpedo | 1990 |
Determination of amino acids critical to the main immunogenic region of intact acetylcholine receptors by in vitro mutagenesis.
Topics: Amino Acids; Animals; Antibodies, Monoclonal; Antigens; Humans; In Vitro Techniques; Mutation; Myasthenia Gravis; Oocytes; Protein Conformation; Receptors, Cholinergic; Torpedo; Xenopus | 1990 |
Genetic restriction of autoreactive acetylcholine receptor-specific T lymphocytes in myasthenia gravis.
Topics: Animals; Antilymphocyte Serum; Cell Line; Cytotoxicity Tests, Immunologic; Epitopes; Histocompatibility Antigens Class II; HLA-DR3 Antigen; Humans; Lymphocyte Activation; Myasthenia Gravis; Receptors, Cholinergic; T-Lymphocytes; Torpedo | 1985 |
Acetylcholine receptor-specific human T-lymphocyte lines.
Topics: Animals; Autoantigens; Cell Line; Epitopes; HLA-DR Antigens; Humans; Lymphocyte Activation; Myasthenia Gravis; Receptors, Antigen, T-Cell; Receptors, Nicotinic; Species Specificity; T-Lymphocytes, Helper-Inducer; Torpedo | 1987 |
Pathogenesis of myasthenia gravis. Acetylcholine receptor-related antigenic determinants in tumor-free thymuses and thymic epithelial tumors.
Topics: Adolescent; Adult; Aged; Animals; Antibodies, Monoclonal; Bungarotoxins; Child; Child, Preschool; Epitopes; Female; Humans; Immunohistochemistry; Infant; Infant, Newborn; Male; Middle Aged; Myasthenia Gravis; Receptors, Cholinergic; Thymoma; Thymus Gland; Thymus Neoplasms; Torpedo | 1988 |
Autoimmune T lymphocytes in myasthenia gravis. Determination of target epitopes using T lines and recombinant products of the mouse nicotinic acetylcholine receptor gene.
Topics: Adult; Amino Acid Sequence; Animals; Antigens, Differentiation, T-Lymphocyte; Autoantigens; Autoimmune Diseases; Cells, Cultured; Epitopes; Female; Haplotypes; HLA-DR Antigens; Humans; Male; Mice; Myasthenia Gravis; Receptors, Nicotinic; Recombinant Proteins; T-Lymphocytes; Torpedo | 1989 |
Evidence against acetylcholine receptor having a main immunogenic region as target for autoantibodies in myasthenia gravis.
Topics: Adult; Animals; Antibodies, Monoclonal; Antibody Specificity; Autoantibodies; Binding Sites, Antibody; Epitopes; Haplorhini; Humans; Mice; Muscles; Myasthenia Gravis; Polymorphism, Genetic; Rats; Receptors, Cholinergic; Torpedo | 1989 |
T-cell reactivity in myasthenia gravis.
Topics: Animals; Autoantigens; Epitopes; Humans; In Vitro Techniques; Lymphocyte Activation; Myasthenia Gravis; Peptides; Protein Conformation; Receptors, Cholinergic; Recombinant Proteins; T-Lymphocytes; Torpedo | 1989 |
Experimental autoimmune myasthenia gravis induced in mice without adjuvant: genetic susceptibility and adoptive transfer of weakness.
Topics: Adjuvants, Immunologic; Animals; Autoantibodies; Autoimmune Diseases; Disease Models, Animal; Disease Susceptibility; Fatigue; Immunization; Immunization, Passive; Lymphocyte Transfusion; Male; Mice; Mice, Inbred Strains; Motor Endplate; Muscles; Myasthenia Gravis; Receptors, Cholinergic; Torpedo | 1989 |
Human T-helper lymphocytes in myasthenia gravis recognize the nicotinic receptor alpha subunit.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Humans; Myasthenia Gravis; Protein Denaturation; Receptors, Cholinergic; Receptors, Nicotinic; T-Lymphocytes, Helper-Inducer; Torpedo | 1987 |
Suppressor T-cell lines and hybridomas in murine myasthenia.
Topics: Animals; Cell Line; Hybridomas; Lymphocyte Cooperation; Mice; Mice, Inbred C57BL; Myasthenia Gravis; Receptors, Nicotinic; T-Lymphocytes, Regulatory; Torpedo | 1987 |
Epstein-Barr virus-transformed B cells can present acetylcholine receptor to autologous autoreactive T cells.
Topics: Animals; Antigen-Presenting Cells; B-Lymphocytes; Cell Transformation, Viral; Cells, Cultured; Herpesvirus 4, Human; Humans; Lymphocyte Activation; Myasthenia Gravis; Receptors, Nicotinic; T-Lymphocytes; Time Factors; Torpedo | 1986 |
Monoclonal antibodies that distinguish between normal and denervated human acetylcholine receptor.
Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Bungarotoxins; Cattle; Chickens; Cross Reactions; Denervation; Fetus; Haplorhini; Humans; Mice; Mice, Inbred BALB C; Muscles; Myasthenia Gravis; Neuromuscular Junction; Rats; Receptors, Cholinergic; Torpedo | 1986 |
Resistance to experimental autoimmune myasthenia gravis in genetically inbred rats. Association with decreased amounts of in situ acetylcholine receptor-antibody complexes.
Topics: Animals; Antibody Formation; Autoantibodies; Crosses, Genetic; Disease Models, Animal; Disease Susceptibility; Electromyography; Female; Immunity, Innate; Muscles; Myasthenia Gravis; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred BUF; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred Strains; Rats, Inbred WF; Rats, Inbred WKY; Receptors, Cholinergic; Species Specificity; Torpedo | 1988 |
Increased levels of acetylcholine receptor alpha-subunit mRNA in experimental autoimmune myasthenia gravis.
Topics: Animals; Antibodies; Disease Models, Animal; DNA; Electric Organ; Female; Macromolecular Substances; Mice; Myasthenia Gravis; Rabbits; Rats; Rats, Inbred Lew; Receptors, Cholinergic; RNA, Messenger; Torpedo; Transcription, Genetic | 1988 |
Myasthenogenic significance of synthetic alpha-subunit peptide 183-200 of Torpedo californica and human acetylcholine receptor.
Topics: Animals; Autoantibodies; Binding, Competitive; Bungarotoxins; Female; Humans; Myasthenia Gravis; Peptide Fragments; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Torpedo | 1988 |
Specific immunosorbents in diagnosis and management of myasthenia gravis.
Topics: Animals; Autoantibodies; Chromatography, Affinity; Cobra Neurotoxin Proteins; Humans; Immunosorbent Techniques; Myasthenia Gravis; Nylons; Rabbits; Receptors, Cholinergic; Serum Albumin, Bovine; Torpedo | 1987 |
Canine and human myasthenia gravis autoantibodies recognize similar regions on the acetylcholine receptor.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Autoantibodies; Dogs; Humans; Myasthenia Gravis; Receptors, Cholinergic; Torpedo | 1988 |
Anti-acetylcholine receptor antibodies in myasthenia gravis: binding to membrane-bound Torpedo AChR.
Topics: Animals; Autoantibodies; Bungarotoxins; Cell Membrane; Complement Activation; Cross Reactions; Humans; Myasthenia Gravis; Receptors, Nicotinic; Torpedo | 1987 |
Passive transfer of experimental autoimmune myasthenia gravis by monoclonal antibodies to the main immunogenic region of the acetylcholine receptor.
Topics: Animals; Antibodies, Monoclonal; Cattle; Electric Organ; Electrophorus; Female; Humans; Immunization, Passive; Mice; Muscles; Myasthenia Gravis; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Species Specificity; Torpedo | 1987 |
Monoclonal antibodies to acetylcholine receptor secreted by human x human hybridomas derived from lymphocytes of a patient with myasthenia gravis.
Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Cell Line; Cell Membrane; Electric Organ; Enzyme-Linked Immunosorbent Assay; Humans; Hybridomas; Myasthenia Gravis; Plasmacytoma; Receptors, Cholinergic; Torpedo | 1986 |
Induction of experimental myasthenia gravis in rhesus monkeys: a model for the study of the human disease.
Topics: Agglutination Tests; Animals; Antibody Formation; Macaca mulatta; Myasthenia Gravis; Receptors, Cholinergic; Torpedo | 1986 |
Region of peptide 125-147 of acetylcholine receptor alpha subunit is exposed at neuromuscular junction and induces experimental autoimmune myasthenia gravis, T-cell immunity, and modulating autoantibodies.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Autoantibodies; Binding Sites; Bungarotoxins; Electrophysiology; Female; Hypersensitivity, Delayed; Motor Endplate; Muscle Denervation; Myasthenia Gravis; Neuromuscular Junction; Peptide Fragments; Peptides, Cyclic; Rats; Receptors, Nicotinic; T-Lymphocytes; Torpedo | 1985 |
Role of the main immunogenic region of acetylcholine receptor in myasthenia gravis. An Fab monoclonal antibody protects against antigenic modulation by human sera.
Topics: Animals; Antibodies, Monoclonal; Antigens; Autoantigens; Binding Sites, Antibody; Humans; Immunoglobulin Fab Fragments; Mice; Muscles; Myasthenia Gravis; Rats; Receptors, Cholinergic; Torpedo | 1985 |
Complement activation in myasthenia gravis plasma by Torpedo acetylcholine receptor liposomes.
Topics: Animals; Antigens; Autoantibodies; Complement Activation; Cross Reactions; Humans; In Vitro Techniques; Liposomes; Myasthenia Gravis; Receptors, Cholinergic; Torpedo | 1985 |