torpedo has been researched along with Alzheimer Disease in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (8.82) | 18.7374 |
| 1990's | 7 (20.59) | 18.2507 |
| 2000's | 9 (26.47) | 29.6817 |
| 2010's | 15 (44.12) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, MR; Boutajangout, A; Mezei, M; Møller, SG; Sadoqi, M | 1 |
| Akbarzadeh, T; Edraki, N; Karimpour-Razkenari, E; Khanavi, M; Mahdavi, M; Najafi, Z; Saeedi, M; Sharifzadeh, M | 1 |
| Akbarzadeh, T; Edraki, N; Larijani, B; Mahdavi, M; Mirfazli, SS; Moghadam, FH; Moradi, A; Nadri, H; Rastegari, A; Saeedi, M | 1 |
| Dallemagne, P; Davis, A; Karila, D; Lalut, J; Lecoutey, C; Maurice, T; Nachon, F; Rochais, C; Santoni, G; Silman, I; Sussman, J; Weik, M | 1 |
| Abdolahi, Z; Ayazgok, B; Emami, S; Forootanfar, H; Foroumadi, A; Haririan, I; Khoobi, M; Küçükkılınç, TT; Mirjalili, BBF; Nadri, H; Salehi, N; Samzadeh-Kermani, A; Sharifzadeh, M | 1 |
| Fereidoonnezhad, M; Manouchehrizadeh, E; Mostoufi, A; Tahanpesar, E | 1 |
| Abd Razik, BM; Basiri, A; Ezzat, MO; Kia, Y; Murugaiyah, V; Osman, H; Salhin, A | 1 |
| Batool, S; Waqar, M | 1 |
| Basile, L; Gazioglu, I; Ginex, T; Guccione, S; Kucukislamoglu, M; Kurt, BZ; Sonmez, F | 1 |
| Andrisano, V; Bartolini, M; Chen, L; De Simone, A; Egea, J; Kang, D; Lamba, D; Lopez, MG; Lou, Y; Pesaresi, A; Samez, S; Stojan, J; Xu, C; Xu, Y; Zha, X; Zhang, L | 1 |
| Emami, S; Foroumadi, A; Golipoor, M; Mahdavi, M; Moradi, A; Nadri, H; Saeedi, M; Shafiee, A | 1 |
| Agondanou, JH; Bureau, R; Dallemagne, P; Dupont, N; Fabis, F; Godard, AM; Lesnard, A; Rault, S; Rochais, C; Sopkova-de Oliveira Santos, J; Stiebing, S | 1 |
| Hu, C; Jin, Z; Li, S; Lin, HQ; Liu, SJ; Wan, DC; Wang, J; Yang, L | 1 |
| Bag, S; Datta, S; Sood, A; Török, M; Tulsan, R | 1 |
| Lozada-García, MC; Soriano-García, M; Tello-Franco, V | 1 |
| Barril, X; Luque, FJ; Orozco, M | 1 |
| Ahmad, VU; Ahmed, A; Azim, MK; Choudhary, MI; Ghayur, MN; Gilani, AU; Jalil, S; Khalid, A; Lodhi, MA; Nawaz, SA; Rode, BM | 1 |
| Nishio, M; Umezawa, Y | 1 |
| Amari, G; Bartolucci, C; Bolzoni, PT; Delcanale, M; Ghidini, E; Lamba, D; Racchi, M; Siotto, M; Villetti, G | 1 |
| Clayton, DF; George, JM; Jin, H; Woods, WS | 1 |
| de Silva, HA; Flanagan, L; Ge, N; Iwai, A; Kittel, A; Masliah, E; Saitoh, T; Yoshimoto, M | 1 |
| Lindstrom, J | 1 |
| Brufani, M; Cellai, L; Perola, E | 1 |
| Kryger, G; Silman, I; Sussman, JL | 1 |
| Greenblatt, HM; Kryger, G; Lewis, T; Silman, I; Sussman, JL | 1 |
| Andrisano, V; Belluti, F; Bisi, A; Cavalli, A; Cavrini, V; Gobbi, S; Rampa, A; Recanatini, M; Valenti, P | 1 |
| Bartolucci, C; Fels, G; Lamba, D; Perola, E; Pilger, C | 1 |
| Bertonati, C; Colella, A; Marta, M; Patamia, M; Pomponi, M | 1 |
| Contreras, JM; Parrot, I; Rival, YM; Sippl, W; Wermuth, CG | 1 |
| Bartolucci, C; Fels, G; Lamba, D; Pilger, C; Tropsha, A | 1 |
| Chapman, J; Hassin-Baer, S; Michaelson, DM; Raphael, M; Stark, V; Wertman, E | 1 |
| Bachar, O; Chapman, J; Korczyn, AD; Michaelson, DM; Wertman, E | 2 |
| Cole, GM; Greco, CM; Kushner, PD; Stephenson, DT; Wright, S | 1 |
2 review(s) available for torpedo and Alzheimer Disease
| Article | Year |
|---|---|
Towards improved acetylcholinesterase inhibitors: a structural and computational approach.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Computational Biology; Drug Design; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Torpedo | 2001 |
Nicotinic acetylcholine receptors in health and disease.
Topics: Acetylcholine; Alzheimer Disease; Anesthetics; Animals; Autoimmune Diseases; Cholinergic Agents; Cholinergic Antagonists; Epilepsy; Ethanol; Female; Keratinocytes; Male; Models, Molecular; Muscle Proteins; Myasthenia Gravis; Nerve Tissue Proteins; Neuromuscular Junction; Nicotine; Parkinson Disease; Pregnancy; Protein Conformation; Receptors, Nicotinic; Schizophrenia; Smoking; Torpedo; Tourette Syndrome | 1997 |
32 other study(ies) available for torpedo and Alzheimer Disease
| Article | Year |
|---|---|
Assessing the binding of cholinesterase inhibitors by docking and molecular dynamics studies.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Hydrogen Bonding; Indans; Molecular Conformation; Molecular Dynamics Simulation; Piperidines; Rivastigmine; Torpedo | 2017 |
Novel tacrine-coumarin hybrids linked to 1,2,3-triazole as anti-Alzheimer's compounds: In vitro and in vivo biological evaluation and docking study.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Catalytic Domain; Cell Line, Tumor; Cholinesterase Inhibitors; Coumarins; Humans; Male; Maze Learning; Molecular Docking Simulation; Molecular Structure; Neuroprotective Agents; Nootropic Agents; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Tacrine; Torpedo; Triazoles | 2019 |
Design, synthesis and anti-Alzheimer's activity of novel 1,2,3-triazole-chromenone carboxamide derivatives.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Apoptosis; Catalytic Domain; Chelating Agents; Cholinesterase Inhibitors; Coumarins; Drug Design; Hydrogen Peroxide; Metals, Heavy; Molecular Docking Simulation; Neuroprotective Agents; PC12 Cells; Rats; Torpedo; Triazoles | 2019 |
Novel multitarget-directed ligands targeting acetylcholinesterase and σ
Topics: Acetylcholinesterase; Alzheimer Disease; Aniline Compounds; Animals; Cholinesterase Inhibitors; Crystallography, X-Ray; Drug Design; Humans; Indoles; Ligands; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Torpedo | 2019 |
Synthesis and biological evaluation of new N-benzylpyridinium-based benzoheterocycles as potential anti-Alzheimer's agents.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Line, Tumor; Cholinesterase Inhibitors; Drug Design; Electrophorus; Heterocyclic Compounds, 2-Ring; Horses; Humans; Hydrogen Peroxide; Kinetics; Molecular Docking Simulation; Neuroprotective Agents; Oxidative Stress; Peptide Fragments; Protein Binding; Protein Multimerization; Pyridinium Compounds; Rats; Torpedo | 2019 |
Alignment-independent 3D-QSAR and molecular docking studies of tacrine-4-oxo-4H-Chromene hybrids as anti-Alzheimer's agents.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Benzopyrans; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Nootropic Agents; Protein Binding; Quantitative Structure-Activity Relationship; Tacrine; Torpedo | 2019 |
Ionic liquid mediated synthesis and molecular docking study of novel aromatic embedded Schiff bases as potent cholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Crystallography, X-Ray; Humans; Hydrocarbons, Aromatic; Ionic Liquids; Molecular Docking Simulation; Schiff Bases; Structure-Activity Relationship; Torpedo | 2014 |
In silico analysis of binding of neurotoxic venom ligands with acetylcholinesterase for therapeutic use in treatment of Alzheimer's disease.
Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Amino Acid Sequence; Animals; Binding Sites; Cholinesterase Inhibitors; Elapid Venoms; Humans; Ligands; Mice; Models, Biological; Molecular Docking Simulation; Molecular Sequence Data; Neurodegenerative Diseases; Protein Binding; Protein Conformation; Protein Interaction Mapping; Sequence Homology, Amino Acid; Torpedo; Venoms | 2015 |
Potential of aryl-urea-benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzofurans; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Dynamics Simulation; Molecular Structure; Structure-Activity Relationship; Thiazoles; Torpedo; Urea | 2015 |
Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Behavior, Animal; Benzofurans; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Crystallography, X-Ray; Drug Design; Humans; Male; Mice; Mice, Inbred ICR; Models, Molecular; Nootropic Agents; Structure-Activity Relationship; Tacrine; Torpedo | 2016 |
Phthalimide-Derived N-Benzylpyridinium Halides Targeting Cholinesterases: Synthesis and Bioactivity of New Potential Anti-Alzheimer's Disease Agents.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Horses; Molecular Docking Simulation; Phthalimides; Pyridinium Compounds; Structure-Activity Relationship; Torpedo | 2016 |
Virtual screening discovery of new acetylcholinesterase inhibitors issued from CERMN chemical library.
Topics: Acetylcholinesterase; Alzheimer Disease; Amino Acid Sequence; Animals; Cholinesterase Inhibitors; Electrophorus; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Sequence Alignment; Small Molecule Libraries; Structure-Activity Relationship; Torpedo | 2010 |
Synthesis and biological evaluation of 3,6-diaryl-7H-thiazolo[3,2-b] [1,2,4]triazin-7-one derivatives as acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Cholinesterase Inhibitors; Databases, Protein; GPI-Linked Proteins; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Structure-Activity Relationship; Thiazoles; Torpedo; Triazines | 2010 |
Pharmacophore Modeling, virtual and in vitro screening for acetylcholinesterase inhibitors and their effects on amyloid-β self- assembly.
Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cholinesterase Inhibitors; Computer-Aided Design; Databases, Pharmaceutical; Drug Design; Humans; Molecular Docking Simulation; Torpedo | 2013 |
Experimental and computational studies on the inhibition of acetylcholinesterase by curcumin and some of its derivatives.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Curcumin; Humans; Molecular Docking Simulation; Torpedo | 2013 |
Juliflorine: a potent natural peripheral anionic-site-binding inhibitor of acetylcholinesterase with calcium-channel blocking potential, a leading candidate for Alzheimer's disease therapy.
Topics: Alkaloids; Alzheimer Disease; Animals; Binding Sites; Calcium; Calcium Channels; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Neutrophils; Protein Binding; Protein Conformation; Torpedo; Tyrosine | 2005 |
CH/pi hydrogen bonds as evidenced in the substrate specificity of acetylcholine esterase.
Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Animals; Biopolymers; Carbon; Crystallography, X-Ray; Dimerization; DNA; Hydrogen Bonding; Ligands; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Software; Substrate Specificity; Torpedo | 2005 |
Structural determinants of Torpedo californica acetylcholinesterase inhibition by the novel and orally active carbamate based anti-alzheimer drug ganstigmine (CHF-2819).
Topics: Acetylcholinesterase; Administration, Oral; Alkaloids; Alzheimer Disease; Animals; Binding Sites; Brain; Carbamates; Cholinesterase Inhibitors; Crystallization; Crystallography, X-Ray; Drug Evaluation, Preclinical; Enzyme Activation; Male; Mice; Models, Molecular; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; Torpedo | 2006 |
Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Animals; Birds; Brain; Canaries; Cattle; Consensus Sequence; DNA, Complementary; Gene Expression Regulation, Developmental; Humans; In Situ Hybridization; Learning; Male; Molecular Sequence Data; Nerve Tissue Proteins; Neural Pathways; Neuronal Plasticity; Phylogeny; Protein Structure, Secondary; Rats; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Subcellular Fractions; Synucleins; Torpedo; Vocalization, Animal | 1995 |
The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; Antibodies; Antibody Specificity; Blotting, Western; Brain; Cattle; Humans; Microscopy, Confocal; Microscopy, Immunoelectron; Molecular Sequence Data; Oligopeptides; Organ Specificity; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sequence Homology, Amino Acid; Synaptophysin; Torpedo | 1995 |
Synthesis and activity studies of N-[omega-N'-(adamant-1'-yl)aminoalkyl]- 2-(4'-dimethylaminophenyl)acetamides: in the search of selective inhibitors for the different molecular forms of acetylcholinesterase.
Topics: Acetamides; Acetylcholinesterase; Alzheimer Disease; Animals; Brain; Catalytic Domain; Cattle; Cholinesterase Inhibitors; Erythrocytes; Humans; Protein Conformation; Solubility; Structure-Activity Relationship; Torpedo | 1998 |
Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Cholinesterase Inhibitors; Crystallography, X-Ray; Donepezil; Drug Design; Indans; Macromolecular Substances; Mice; Models, Molecular; Nootropic Agents; Piperidines; Protein Conformation; Solvents; Structure-Activity Relationship; Substrate Specificity; Torpedo | 1999 |
Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Cholinesterase Inhibitors; Drug Design; Galantamine; Galanthus; Hydrogen Bonding; Molecular Structure; Stereoisomerism; Torpedo; X-Ray Diffraction | 1999 |
Acetylcholinesterase inhibitors for potential use in Alzheimer's disease: molecular modeling, synthesis and kinetic evaluation of 11H-indeno-[1,2-b]-quinolin-10-ylamine derivatives.
Topics: Acetylcholinesterase; Alzheimer Disease; Aminoquinolines; Animals; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computer Simulation; Electrons; Indenes; Inhibitory Concentration 50; Kinetics; Ligands; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Tacrine; Torpedo | 2000 |
Three-dimensional structure of a complex of galanthamine (Nivalin) with acetylcholinesterase from Torpedo californica: implications for the design of new anti-Alzheimer drugs.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Cholinesterase Inhibitors; Crystallization; Crystallography, X-Ray; Cyclohexanes; Cyclohexenes; Drug Design; Galantamine; Models, Molecular; Nootropic Agents; Protein Conformation; Structure-Activity Relationship; Torpedo | 2001 |
Inhibition of AChE: structure-activity relationship among conformational transition of Trp84 and biomolecular rate constant.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Carbamates; Cholinesterase Inhibitors; Kinetics; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Thermodynamics; Torpedo | 2000 |
Structure-based 3D QSAR and design of novel acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Cholinesterase Inhibitors; Computer Simulation; Crystallography, X-Ray; Donepezil; Drug Design; Humans; Indans; Models, Molecular; Piperidines; Protein Conformation; Quantitative Structure-Activity Relationship; Thermodynamics; Torpedo | 2001 |
Accurate prediction of the bound conformation of galanthamine in the active site of Torpedo californica acetylcholinesterase using molecular docking.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Catalytic Domain; Cholinesterase Inhibitors; Computer Simulation; Crystallography, X-Ray; Galantamine; Humans; Models, Molecular; Molecular Conformation; Nootropic Agents; Protein Conformation; Software; Torpedo | 2001 |
Antibodies from Down's syndrome patients bind to the same cholinergic neurofilament protein recognized by Alzheimer's disease antibodies.
Topics: Adult; Alzheimer Disease; Animals; Antibodies; Choline O-Acetyltransferase; Down Syndrome; Female; Humans; Immunoglobulin G; Male; Middle Aged; Neurofilament Proteins; Torpedo | 1992 |
Alzheimer's disease antibodies bind specifically to a neurofilament protein in Torpedo cholinergic neurons.
Topics: Aged; Alzheimer Disease; Animals; Antibodies; Electric Organ; Epitopes; Female; Humans; Immunoglobulin G; Intermediate Filament Proteins; Male; Neurofilament Proteins; Neurons; Parasympathetic Nervous System; Phosphorylation; Torpedo | 1989 |
Serum antibodies to cholinergic neurons in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Immunoglobulin G; Neurons; Peptide Fragments; Receptors, Cholinergic; Receptors, Nicotinic; Torpedo | 1989 |
Monoclonal antibody Tor 23 binds a subset of neural cells in the human cortex and displays an altered binding distribution in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Antibodies, Monoclonal; Antigens, Surface; Cell Membrane; Cerebral Cortex; Choline; Electric Organ; Fluorescent Antibody Technique; Frontal Lobe; Humans; Immunoblotting; Immunoenzyme Techniques; Middle Aged; Nerve Endings; Nerve Tissue Proteins; Neurons; Torpedo | 1989 |