Page last updated: 2024-09-04

torcetrapib and Dyslipidemias

torcetrapib has been researched along with Dyslipidemias in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (47.83)29.6817
2010's12 (52.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avorn, J; Franklin, JM; Hey, SP; Kesselheim, AS1
Abdallah, M; Abi Rafeh, N; Bhat, T; El-Sayegh, S; Kalantar-Zadeh, K; Khoueiry, G; Lafferty, J; Raza, M; Saiful, F1
Cai, J; Chen, C; Hu, Z; Li, C; Li, Y; Liu, L; Luo, H; Pei, F; Zeng, C; Zhang, W; Zhou, F; Zhou, L1
Briand, F; Costard, C; Muzotte, E; Prunet-Marcassus, B; Sordello, S; Sulpice, T; Thieblemont, Q1
Hermann, M; Ruschitzka, FT1
Buckley, BM; Burgess, T; Capponi, AM; Kallend, D; Kastelein, JJ; Niesor, EJ; Stein, EA; Steiner, G; Stroes, ES1
Bots, ML; Dogan, S; Duivenvoorden, R; Evans, GW; Grobbee, DE; Kastelein, JJ; Shear, CL; Visseren, FL1
Athyros, VG; Katsiki, N; Mikhailidis, DP1
Devaraj, S; Jialal, I1
Barter, PJ; Boekholdt, SM; Breazna, A; Kastelein, JJ; Rye, KA; Tardif, JC; Waters, DD1
André, A; Briand, F; Ouguerram, K; Sulpice, T; Thieblemont, Q1
Shinkai, H1
Briand, F; Muzotte, E; Sulpice, T; Thieblemont, Q1
Angelin, B; Asztalos, BF; Björkhem, I; Brousseau, ME; Diffenderfer, MR; Digenio, AG; Mancuso, JP; Millar, JS; Nartsupha, C; Rader, DJ; Rudling, M; Schaefer, EJ; Welty, FK; Wolfe, ML1
Zareba, G1
Aronow, WS1
Bots, ML; Duggan, WT; Evans, GW; Grobbee, DE; Kastelein, JJ; Revkin, JH; Riley, WA; Shear, CL; Tegeler, CH; Vicari, RM; Visseren, FL1
El Harchaoui, K; Kastelein, JJ; Stroes, ES; van der Steeg, WA1
Duriez, P2
Suckling, K1
Chapman, MJ; Guérin, M; Kontush, A1

Reviews

7 review(s) available for torcetrapib and Dyslipidemias

ArticleYear
Success, Failure, and Transparency in Biomarker-Based Drug Development: A Case Study of Cholesteryl Ester Transfer Protein Inhibitors.
    Circulation. Cardiovascular quality and outcomes, 2017, Volume: 10, Issue:6

    Topics: Amides; Anticholesteremic Agents; Benzodiazepines; Biomarkers, Pharmacological; Cholesterol Ester Transfer Proteins; Drug Approval; Drug Discovery; Dyslipidemias; Endpoint Determination; Esters; Humans; Lipids; Oxazolidinones; Predictive Value of Tests; Quinolines; Reproducibility of Results; Sulfhydryl Compounds; Time Factors; Treatment Outcome

2017
High-density lipoprotein in uremic patients: metabolism, impairment, and therapy.
    International urology and nephrology, 2014, Volume: 46, Issue:1

    Topics: Acetamides; Acetates; Acetyl-CoA C-Acetyltransferase; Anti-Inflammatory Agents; Anticholesteremic Agents; Antioxidants; Apolipoprotein A-I; Atherosclerosis; Cholesterol; Cholesterol Ester Transfer Proteins; Dyslipidemias; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipoproteins, HDL; Niacin; PPAR alpha; Quinolines; Renal Insufficiency, Chronic; Sulfonamides; Sulfonic Acids; Uremia

2014
Cholesteryl ester transfer protein inhibitors in the treatment of dyslipidemia: a systematic review and meta-analysis.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Adult; Amides; Anticholesteremic Agents; Benzodiazepines; Blood Pressure; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Dyslipidemias; Esters; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Oxazolidinones; Quinolines; Randomized Controlled Trials as Topic; Sulfhydryl Compounds; Treatment Outcome; Triglycerides

2013
The hypertension peril: lessons from CETP inhibitors.
    Current hypertension reports, 2009, Volume: 11, Issue:1

    Topics: Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Dyslipidemias; Humans; Hypertension; Quinolines

2009
Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases.
    Vascular health and risk management, 2012, Volume: 8

    Topics: Amides; Animals; Biomarkers; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Dyslipidemias; Esters; Humans; Hypolipidemic Agents; Oxazolidinones; Quinolines; Sulfhydryl Compounds; Treatment Outcome

2012
The role of CETP inhibition in dyslipidemia.
    Current atherosclerosis reports, 2007, Volume: 9, Issue:2

    Topics: Amides; Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Clinical Trials as Topic; Dyslipidemias; Esters; Female; Humans; Hyperlipoproteinemia Type II; Hypertriglyceridemia; Male; Quinolines; Sulfhydryl Compounds

2007
Spotlight on HDL-raising therapies: insights from the torcetrapib trials.
    Nature clinical practice. Cardiovascular medicine, 2008, Volume: 5, Issue:6

    Topics: Aldosterone; Anticholesteremic Agents; Blood Pressure; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Clinical Trials as Topic; Dyslipidemias; Humans; Hypertension; Quinolines

2008

Trials

6 trial(s) available for torcetrapib and Dyslipidemias

ArticleYear
Safety and tolerability of dalcetrapib.
    The American journal of cardiology, 2009, Jul-01, Volume: 104, Issue:1

    Topics: Amides; Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Coronary Artery Disease; Double-Blind Method; Dyslipidemias; Esters; Female; Humans; Incidence; Male; Middle Aged; Quinolines; Risk Assessment; Risk Factors; Sulfhydryl Compounds

2009
Ultrasound protocols to measure carotid intima-media thickness in trials; comparison of reproducibility, rate of progression, and effect of intervention in subjects with familial hypercholesterolemia and subjects with mixed dyslipidemia.
    Annals of medicine, 2010, Volume: 42, Issue:6

    Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Carotid Artery, Internal; Disease Progression; Dyslipidemias; Female; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Pyrroles; Quinolines; Randomized Controlled Trials as Topic; Reproducibility of Results; Tunica Intima; Ultrasonography

2010
Effect of torcetrapib on glucose, insulin, and hemoglobin A1c in subjects in the Investigation of Lipid Level Management to Understand its Impact in Atherosclerotic Events (ILLUMINATE) trial.
    Circulation, 2011, Aug-02, Volume: 124, Issue:5

    Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Blood Glucose; Cholesterol, HDL; Diabetes Mellitus, Type 2; Dyslipidemias; Female; Glycated Hemoglobin; Heptanoic Acids; Homeostasis; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Prospective Studies; Pyrroles; Quinolines

2011
Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:5

    Topics: Anticholesteremic Agents; Apolipoprotein A-I; Atorvastatin; Bile Acids and Salts; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cohort Studies; Drug Therapy, Combination; Dyslipidemias; Feces; Glycoproteins; Heptanoic Acids; Humans; Pyrroles; Quinolines; Sterols

2005
Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial.
    Lancet (London, England), 2007, Jul-14, Volume: 370, Issue:9582

    Topics: Anticholesteremic Agents; Atorvastatin; Blood Pressure; Carotid Arteries; Cholesterol; Double-Blind Method; Dyslipidemias; Female; Heptanoic Acids; Humans; Male; Middle Aged; Pyrroles; Quinolines; Tunica Intima

2007
CETP inhibition.
    Lancet (London, England), 2007, Dec-08, Volume: 370, Issue:9603

    Topics: Anticholesteremic Agents; Blood Pressure; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Dyslipidemias; Humans; Quinolines

2007

Other Studies

10 other study(ies) available for torcetrapib and Dyslipidemias

ArticleYear
Raising HDL with CETP inhibitor torcetrapib improves glucose homeostasis in dyslipidemic and insulin resistant hamsters.
    Atherosclerosis, 2014, Volume: 233, Issue:2

    Topics: AMP-Activated Protein Kinases; Animals; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins E; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cricetinae; Deoxyglucose; Diet, Atherogenic; Disease Models, Animal; Drug Evaluation, Preclinical; Dyslipidemias; Enzyme Activation; Feces; Glucose; Homeostasis; Hyperglycemia; Insulin Resistance; Male; Mesocricetus; Muscle, Skeletal; Quinolines; Random Allocation; Species Specificity

2014
Trial watch: hope renewed for strategy to raise HDL cholesterol.
    Nature reviews. Drug discovery, 2011, Volume: 10, Issue:1

    Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Clinical Trials, Phase II as Topic; Dyslipidemias; Humans; Oxazolidinones; Quinolines; Risk Factors

2011
The DEFINE study: a bright future for CETP inhibitors?
    Expert opinion on investigational drugs, 2011, Volume: 20, Issue:3

    Topics: Animals; Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Dyslipidemias; Humans; Oxazolidinones; Quinolines

2011
Novel cholesteryl ester transfer protein inhibitors: promising therapy for dyslipidemia?
    Metabolic syndrome and related disorders, 2011, Volume: 9, Issue:3

    Topics: Cholesterol Ester Transfer Proteins; Drugs, Investigational; Dyslipidemias; Humans; Hypolipidemic Agents; Molecular Targeted Therapy; Oxazolidinones; Quinolines

2011
CETP inhibitor torcetrapib promotes reverse cholesterol transport in obese insulin-resistant CETP-ApoB100 transgenic mice.
    Clinical and translational science, 2011, Volume: 4, Issue:6

    Topics: Animals; Anticholesteremic Agents; Apolipoprotein B-100; Bile Acids and Salts; Biological Transport; Body Weight; Cells, Cultured; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Dyslipidemias; Humans; Insulin Resistance; Lipoproteins; Macrophages; Male; Mice; Mice, Transgenic; Obesity; Quinolines

2011
Upregulating reverse cholesterol transport with cholesteryl ester transfer protein inhibition requires combination with the LDL-lowering drug berberine in dyslipidemic hamsters.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:1

    Topics: Animals; Berberine; Biological Transport; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Cholesterol, HDL; Cholesterol, LDL; Cricetinae; Disease Models, Animal; Down-Regulation; Drug Therapy, Combination; Dyslipidemias; Feces; Hypolipidemic Agents; Kinetics; Lipoproteins, LDL; Liver; Liver X Receptors; Macrophages; Male; Mesocricetus; Orphan Nuclear Receptors; Quinolines; Up-Regulation

2013
Torcetrapib and atorvastatin: a novel combination therapy for dyslipidemia.
    Drugs of today (Barcelona, Spain : 1998), 2006, Volume: 42, Issue:2

    Topics: Animals; Atorvastatin; Cholesterol, HDL; Drug Therapy, Combination; Dyslipidemias; Heptanoic Acids; Humans; Pyrroles; Quinolines

2006
Intensive statin treatment or combination therapy in high-risk patients.
    Preventive cardiology, 2007,Winter, Volume: 10, Issue:1

    Topics: Drug Therapy, Combination; Dyslipidemias; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Quinolines; Risk Factors

2007
The ENHANCE Study: an unusual publication of trial data raises questions beyond ezetimibe.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:7

    Topics: Anticholesteremic Agents; Atherosclerosis; Azetidines; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Controlled Clinical Trials as Topic; Drug Design; Dyslipidemias; Ezetimibe; Humans; Quinolines

2008
Treating high-density lipoprotein cholesterol: a return to inhibition of cholesteryl ester transfer protein?
    Current atherosclerosis reports, 2008, Volume: 10, Issue:3

    Topics: Anticholesteremic Agents; Atherosclerosis; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Dyslipidemias; Heart Diseases; Humans; Oxazolidinones; Quinolines; Risk Factors

2008