topotecan has been researched along with Sarcoma in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Ebinger, M; Fuchs, J; Heinz, AT; Klingebiel, T; Koscielniak, E; Kratz, CP; Ljungman, G; Münter, MW; Pajtler, KW; Rößler, J; Schönstein, A; Seitz, G; Sparber-Sauer, M; Stegmaier, S; Timmermann, B; Vokuhl, C; von Kalle, T | 1 |
| Abbinanti, S; Agulnik, M; Attia, S; Cehic, R; Charlson, J; Helenowski, I; Hirbe, AC; Milhem, M; Mohindra, N; Monga, V; Okuno, S; Oppelt, P; Robinson, S; Schulte, B; Van Tine, BA | 1 |
| Bauer, F; Burdach, S; Filipiak-Pittroff, B; von Luettichau, I; Wawer, A | 1 |
| Beilken, A; Bochennek, K; Claviez, A; Dantonello, T; Dirksen, U; Klingebiel, T; Koscielniak, E; Sauerbrey, A | 1 |
| Fan, Y; He, H; Qi, X; Wu, Z | 1 |
| Grünwald, V; Hartmann, JT; Hertenstein, B; Issels, RD; Krause, S; Nicolo, KS; Papesch, E; Sturm, I | 1 |
| Blomen, V; Brummelkamp, TR; Hoogstraat, M; Janssen, L; Lips, EH; Neefjes, J; Pang, B; Qiao, X; van der Zanden, SY; Wessels, L; Wijdeven, RH | 1 |
| Borgel, SD; Burkett, S; Butcher, DO; Hollingshead, M; Kenney, S; Raffeld, M; Schrump, DS; Shoemaker, RH; Stockwin, LH; Stone, G; Vistica, DT | 1 |
| Bokemeyer, C; Hartmann, JT; Issels, R; Kanz, L; Oechsle, K; Pink, D; Reichardt, P; Schneller, F | 1 |
| Adamson, PC; Blaney, SM; Bradfield, S; Franklin, J; Hawkins, DS; Krailo, M; Reaman, G; Whitlock, JA | 1 |
| Gupta, AA; Pappo, AS | 1 |
| Blackstein, M; Bogues, W; Boos, G; Bramwell, VH; Eisenhauer, EA; Jolivet, J; Knowling, M | 1 |
| Baccanari, D; Bendele, R; Brown, E; Chiang, S; Desjardins, JP; Dihel, LC; Emerson, DL; Gill, SC; Hamilton, M; LeRay, JD; Luzzio, MJ; Moon-McDermott, L; Moynihan, K; Richardson, FC; Tomkinson, B | 1 |
| Cheung, NK; Kramer, K; Kushner, BH; Meyers, PA; Wollner, N | 1 |
| Anderson, JR; Barr, FG; Crist, WM; Donaldson, SS; Maurer, HM; Pappo, AS; Qualman, SJ; Raney, RB; Wiener, ES | 1 |
| Antman, K; Budd, GT; Hutchins, LF; Petruska, PJ; Rankin, C; Wong, L | 1 |
2 review(s) available for topotecan and Sarcoma
| Article | Year |
|---|---|
New drugs for the treatment of metastatic or refractory soft tissue sarcomas in children.
Topics: Animals; Camptothecin; Child; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Humans; Irinotecan; Rhabdomyosarcoma; Sarcoma; Survival Rate; Topoisomerase I Inhibitors; Topotecan | 2006 |
Rhabdomyosarcoma and undifferentiated sarcoma in the first two decades of life: a selective review of intergroup rhabdomyosarcoma study group experience and rationale for Intergroup Rhabdomyosarcoma Study V.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Infant; Male; Melphalan; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Neoplasm Staging; Pilot Projects; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Rhabdomyosarcoma; Salvage Therapy; Sarcoma; Soft Tissue Neoplasms; Survival Rate; Topotecan; Treatment Outcome; Vincristine | 2001 |
7 trial(s) available for topotecan and Sarcoma
| Article | Year |
|---|---|
Phase II study of pazopanib with oral topotecan in patients with metastatic and non-resectable soft tissue and bone sarcomas.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Drug Administration Schedule; Humans; Indazoles; Male; Middle Aged; Neoplasm Metastasis; Osteosarcoma; Prospective Studies; Pyrimidines; Sarcoma; Sulfonamides; Topotecan; Treatment Outcome; Young Adult | 2021 |
Response of children with stage IV soft tissue sarcoma to topotecan and carboplatin: a phase II window trial of the cooperative soft tissue sarcoma group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Cohort Studies; Combined Modality Therapy; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Neoadjuvant Therapy; Neoplasm Staging; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Sarcoma, Synovial; Soft Tissue Neoplasms; Survival Rate; Topotecan; Treatment Outcome | 2013 |
An open label, non-comparative phase II study of topotecan as salvage treatment for patients with soft tissue sarcoma.
Topics: Adult; Aged; Confidence Intervals; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Nausea; Salvage Therapy; Sarcoma; Survival Rate; Topotecan | 2003 |
Topotecan by 21-day continuous infusion in children with relapsed or refractory solid tumors: a Children's Oncology Group study.
Topics: Adolescent; Adult; Astrocytoma; Child; Child, Preschool; Dose-Response Relationship, Drug; Fatigue; Female; Humans; Infusions, Intravenous; Male; Maximum Tolerated Dose; Neoplasm Recurrence, Local; Neuroblastoma; Neuroectodermal Tumors, Primitive; Neutropenia; Recurrence; Sarcoma; Survival Rate; Thrombocytopenia; Time Factors; Topotecan; Treatment Outcome | 2006 |
Phase II study of topotecan (NSC 609 699) in patients with recurrent or metastatic soft tissue sarcoma.
Topics: Adolescent; Adult; Antineoplastic Agents; Camptothecin; Female; Humans; Male; Neoplasm Metastasis; Retrospective Studies; Sarcoma; Topotecan | 1995 |
Pilot study of topotecan and high-dose cyclophosphamide for resistant pediatric solid tumors.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Male; Neuroblastoma; Pilot Projects; Salvage Therapy; Sarcoma; Topotecan | 2000 |
Phase II trial of topotecan by continuous infusion in patients with advanced soft tissue sarcomas, a SWOG study. Southwest Oncology Group.
Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Sarcoma; Topotecan | 2002 |
7 other study(ies) available for topotecan and Sarcoma
| Article | Year |
|---|---|
Second-line treatment of pediatric patients with relapsed rhabdomyosarcoma adapted to initial risk stratification: Data of the European Soft Tissue Sarcoma Registry (SoTiSaR).
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Chronic Disease; Cyclophosphamide; Etoposide; Humans; Polyketides; Recurrence; Retrospective Studies; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Topotecan | 2023 |
Escalating topotecan in combination with treosulfan has acceptable toxicity in advanced pediatric sarcomas.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Sarcoma; Topotecan | 2013 |
Hyaluronic acid-grafted polyamidoamine dendrimers enable long circulation and active tumor targeting simultaneously.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Dendrimers; Drug Carriers; Drug Delivery Systems; HCT116 Cells; Humans; Hyaluronic Acid; Mice; Rats; Sarcoma; Topoisomerase I Inhibitors; Topotecan | 2015 |
Topotecan plus cyclophosphamide in adults with relapsed or refractory pediatric-type sarcoma: a retrospective analysis from the German Sarcoma Medical Oncology Group (AIO).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies; Sarcoma; Survival Analysis; Topotecan; Young Adult | 2015 |
Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Capecitabine; Carcinoma; Chromosomal Proteins, Non-Histone; CRISPR-Cas Systems; Cyclophosphamide; DNA Helicases; DNA-Binding Proteins; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Gene Expression Profiling; Genome-Wide Association Study; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Neoplasm Proteins; Nuclear Proteins; RNA Interference; RNA, Small Interfering; Sarcoma; SMARCB1 Protein; Taxoids; Topoisomerase II Inhibitors; Topotecan; Transcription Factors; Triple Negative Breast Neoplasms | 2015 |
Therapeutic vulnerability of an in vivo model of alveolar soft part sarcoma (ASPS) to antiangiogenic therapy.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD34; Antineoplastic Agents; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Bevacizumab; Chromosomes, Human, Pair 17; Chromosomes, Human, X; Disease Models, Animal; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neovascularization, Pathologic; Oncogene Proteins, Fusion; Sarcoma; Topotecan; Translocation, Genetic; Transplantation, Heterologous; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2009 |
Antitumor efficacy, pharmacokinetics, and biodistribution of NX 211: a low-clearance liposomal formulation of lurtotecan.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Camptothecin; Carbon Radioisotopes; Drug Carriers; Female; Humans; KB Cells; Liposomes; Mice; Mice, Nude; Sarcoma; Tissue Distribution; Topotecan; Xenograft Model Antitumor Assays | 2000 |