Page last updated: 2024-08-24

topotecan and Hypoxia

topotecan has been researched along with Hypoxia in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Bruick, RK; Hossain, CF; Mohammed, KA; Nagle, DG; Zhang, L; Zhou, YD1
Kao, G; Xiao, J; Xu, Y; Yan, M; Zhang, Y; Zhou, K1
Eschenko, N; Galkina, O; Lomert, E; Lyanguzov, A; Nimiritsky, P; Rybnikova, E; Sarieva, K; Tyulkova, E; Vetrovoy, O1
de Lange, J; Jager, MJ; Jochemsen, AG; Lodder, K; Ly, LV; Teunisse, AF; Verlaan-de Vries, M1
Hansen, LT; Kristjansen, PE; Lund, EL1

Other Studies

5 other study(ies) available for topotecan and Hypoxia

ArticleYear
Laurenditerpenol, a new diterpene from the tropical marine alga Laurenciaintricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells.
    Journal of natural products, 2004, Volume: 67, Issue:12

    Topics: Antineoplastic Agents; Breast Neoplasms; Diterpenes; DNA-Binding Proteins; Dose-Response Relationship, Drug; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mitochondria; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Rhodophyta; Stereoisomerism; Transcription Factors

2004
Hypoxia-inducible transcription factor-1α inhibition by topotecan protects against lipopolysaccharide-induced inflammation and apoptosis of cardiomyocytes.
    Biomedical engineering online, 2021, Aug-31, Volume: 20, Issue:1

    Topics: Apoptosis; Humans; Hypoxia; Inflammation; Lipopolysaccharides; Myocytes, Cardiac; Topotecan; Transcription Factors

2021
Pharmacological HIF1 Inhibition Eliminates Downregulation of the Pentose Phosphate Pathway and Prevents Neuronal Apoptosis in Rat Hippocampus Caused by Severe Hypoxia.
    Journal of molecular neuroscience : MN, 2020, Volume: 70, Issue:5

    Topics: Animals; Apoptosis; Down-Regulation; Hippocampus; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Neurons; Pentose Phosphate Pathway; Rats; Rats, Wistar; Topotecan

2020
Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma.
    Oncogene, 2012, Mar-01, Volume: 31, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Drug Synergism; Furans; Humans; Hypoxia; Imidazoles; Melanoma; Melanoma, Experimental; Mice; Phosphorylation; Piperazines; Protein Serine-Threonine Kinases; Topotecan; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Uveal Neoplasms

2012
Augmenting tumor sensitivity to topotecan by transient hypoxia.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Carcinoma, Small Cell; Cell Hypoxia; Cell Line, Tumor; Central Nervous System Neoplasms; Glioblastoma; Glucose Transporter Type 1; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Topotecan; Tumor Burden; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2005