topotecan has been researched along with Hepatocellular Carcinoma in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 4 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Gan, J; Gao, Y; Guo, S; Ning, S; Sun, Y; Wang, P; Wang, X; Xiao, Y; Zhang, Y; Zhi, H; Zhou, H | 1 |
| Fu, W; Kai, GY; Li, L; Liu, XF; Liu, YQ; Peng, LZ; Xu, CR; Zhang, M; Zhang, ZJ; Zhu, LZ | 1 |
| Bai, YP; Li, L; Liu, YQ; Luo, HB; Peng, LZ; Wang, ZP; Xu, CR; Yan, JX; Yang, CJ; Zhang, M; Zhang, ZJ; Zhu, LZ | 1 |
| Bakhutashvili, I; Banovac, F; Esparza-Trujillo, JA; Henman, A; Karanian, JW; Krishnasamy, VP; Levy, EB; Lewis, AL; Mikhail, AS; Negussie, AH; Pritchard, WF; Tang, Y; Wakim, PG; Willis, SL; Wood, BJ; Woods, DL | 1 |
| Baghy, K; Bocsi, J; Dudás, J; Füle, T; Fullár, A; Kovalszky, I; Kudaibergenova, S | 1 |
| Klopfenstein, KJ; Ruymann, FB; Schuller, DE; Scott, S | 1 |
| Pu, SP; Zhang, J; Zhou, YJ | 1 |
| Byun, JH; Choi, DS; Choi, SH; Kim, BS; Kim, HJ; Ko, JY; Lee, GY; Seo, YT; Yang, SH | 1 |
| de Gelder, V; De Ridder, L; De Vos, F; Lambert, B; Slegers, G; Thierens, H; Van de Wiele, C | 1 |
| Benedetti, JK; Macdonald, JS; Natale, RB; O'Rourke, MA; Wall, JG | 1 |
| Alexandre, J; Azoulay, D; Goldwasser, F; Gornet, JM; Gross-Goupil, M; Misset, JL; Romain, D; Tigaud, JM | 1 |
3 trial(s) available for topotecan and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Phase II study to topotecan and cisplatin in advanced hepatocellular carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Humans; Liver Neoplasms; Male; Middle Aged; Topotecan; Treatment Outcome | 2003 |
Phase II trial to topotecan in hepatocellular carcinoma: a Southwest Oncology Group study.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Agents; Carcinoma, Hepatocellular; Enzyme Inhibitors; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neutropenia; Thrombocytopenia; Topoisomerase I Inhibitors; Topotecan | 1997 |
Combination of topotecan and oxaliplatin in inoperable hepatocellular cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Topotecan | 2002 |
8 other study(ies) available for topotecan and Hepatocellular Carcinoma
| Article | Year |
|---|---|
PD-L1-Mediated Immunosuppression in Hepatocellular Carcinoma: Relationship with Macrophages Infiltration and Inflammatory Response Activity.
Topics: B7-H1 Antigen; Carcinoma, Hepatocellular; Cytokines; Dasatinib; Humans; Immunosuppression Therapy; Inflammation; Liver Neoplasms; Macrophages; Programmed Cell Death 1 Receptor; Topotecan; Tumor Microenvironment; Vemurafenib | 2022 |
Anti-tumor effects and mechanism of a novel camptothecin derivative YCJ100.
Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Topoisomerases, Type I; Female; Humans; Liver Neoplasms; Mice; Molecular Docking Simulation; Pancreatic Neoplasms; Topoisomerase I Inhibitors; Topotecan; Xenograft Model Antitumor Assays | 2022 |
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I.
Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Hepatocellular; DNA Topoisomerases, Type I; Humans; Liver Neoplasms; Mice; Topoisomerase I Inhibitors; Topotecan | 2023 |
Safety and Tolerability of Topotecan-Eluting Radiopaque Microspheres for Hepatic Chemoembolization in a Rabbit Preclinical Model.
Topics: Animals; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Humans; Irinotecan; Liver Neoplasms; Liver Neoplasms, Experimental; Microspheres; Rabbits; Topoisomerase I Inhibitors; Topotecan | 2020 |
Heparin and liver heparan sulfate can rescue hepatoma cells from topotecan action.
Topics: Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; DNA Topoisomerases, Type I; DNA, Neoplasm; Hep G2 Cells; Heparin; Heparitin Sulfate; Humans; Liver; Liver Neoplasms; Topotecan | 2014 |
Prolonged survival with continuous infusion topotecan: a report of 2 cases.
Topics: Adolescent; Antineoplastic Agents; Carcinoma, Hepatocellular; Child; Child, Preschool; Female; Head and Neck Neoplasms; Histiocytoma, Malignant Fibrous; Humans; Infusions, Intravenous; Liver Neoplasms; Neoplasms, Second Primary; Palliative Care; Survival; Topotecan | 2008 |
[Preliminary study of apoptosis of human hepatocarcinoma cell line HepG2 induced by topotecan].
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Topotecan; Tumor Cells, Cultured | 2002 |
Assessment of supra-additive effects of cytotoxic drugs and low dose rate irradiation in an in vitro model for hepatocellular carcinoma.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cobalt Radioisotopes; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Radiation; Fluorouracil; Gamma Rays; Gemcitabine; Glucose Transporter Type 1; Humans; Rhenium; Topotecan | 2006 |