topotecan has been researched along with Central Nervous System Neoplasm in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Bosaleh, A; Chantada, G; Deu, A; Fandiño, A; Requejo, F; Rodriguez, A; Sampor, C; Schaiquevich, P; Sgroi, M; Zugbi, S | 1 |
| Barbour, M; Bujold, KE; Dandekar, S | 1 |
| Annibali, O; Avvisati, G; Cellini, F; Greco, R; Nobile, C; Petrucci, MT; Quattrocchi, CC; Tirindelli, MC | 1 |
| Yamanaka, R | 1 |
| Boulad, F; Dunkel, IJ; Gilheeney, SW; Khakoo, Y; Souweidane, M; Wolden, S | 1 |
| Kiewe, P; Korfel, A; Reinwald, M; Thiel, E | 1 |
| Anders, K; Feldmann, HJ; Fietkau, RJ; Grabenbauer, GG; Klautke, G; Krauseneck, P; Sauer, R; Staab, HJ; Weiser, S | 1 |
| Hansen, LT; Kristjansen, PE; Lund, EL | 1 |
| Cheung, NK; Danis, K; Kernan, NA; Kramer, K; Kushner, BH; Modak, S; Reich, LM | 1 |
| Chuansumrit, A; Hongeng, S; Pakakasama, S; Sirachainan, N; Tuntiyatorn, L; Visudtibhan, A | 1 |
| Birkmann, J; Fischer, L; Jahnke, K; Klasen, HA; Korfel, A; Martus, P; Thiel, E | 1 |
| Dethling, J; Fink, T; Hans, K; Koschel, G; Lorenz, R; Mueller, C; Schade-Brittinger, C; Schroeder, H; Seifart, U; Wolf, M | 1 |
| Bigner, DD; Friedman, HS; Houghton, PJ; Keir, S; Schold, SC | 1 |
| Boothman, DA; Lamond, JP; Mehta, MP | 1 |
| Burger, PC; Friedman, HS; Heideman, RL; Horn, M; Kadota, RP; Kepner, JL; Kun, LE; Kuttesch, JF; Stewart, CF | 1 |
| Egorin, MJ; Lüftner, DI; Natale, JJ; Possinger, K; Richter, T; Schweigert, M; Sezer, O; Zamboni, WC | 1 |
| Fisher, B; Johnson, DW; Macdonald, D; Roa, W; Won, M | 1 |
1 review(s) available for topotecan and Central Nervous System Neoplasm
| Article | Year |
|---|---|
[Medical management of primary central nervous system lymphoma refractory or resistant to standard of care treatment].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Dacarbazine; Drug Discovery; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Methotrexate; Neoplasm Recurrence, Local; Rituximab; Salvage Therapy; Temozolomide; Topotecan | 2009 |
7 trial(s) available for topotecan and Central Nervous System Neoplasm
| Article | Year |
|---|---|
Thiotepa/topotecan/carboplatin with autologous stem cell rescue in recurrent/refractory/poor prognosis pediatric malignancies of the central nervous system.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Neoplasm Recurrence, Local; Prognosis; Thiotepa; Topotecan; Young Adult | 2010 |
Prolonged infusional topotecan and accelerated hyperfractionated 3d-conformal radiation in patients with newly diagnosed glioblastoma--a phase I study.
Topics: Adult; Aged; Antineoplastic Agents; Central Nervous System Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Infusions, Intravenous; Maximum Tolerated Dose; Middle Aged; Neutropenia; Radiotherapy, Conformal; Sepsis; Sinusitis; Thrombocytopenia; Topotecan | 2002 |
Topotecan, thiotepa, and carboplatin for neuroblastoma: failure to prevent relapse in the central nervous system.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Male; Neoplasm Recurrence, Local; Neuroblastoma; Thiotepa; Topotecan; Treatment Failure | 2006 |
Prospective trial on topotecan salvage therapy in primary CNS lymphoma.
Topics: Adult; Aged; Antineoplastic Agents; Central Nervous System Neoplasms; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Lymphoma; Male; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Remission Induction; Salvage Therapy; Survival Analysis; Topotecan | 2006 |
Randomised phase II study comparing topotecan/carboplatin administration for 5 versus 3 days in the treatment of extensive-stage small-cell lung cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Small Cell; Central Nervous System Neoplasms; Cisplatin; Female; Humans; Infusions, Intravenous; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Survival Rate; Time Factors; Topotecan; Treatment Outcome | 2007 |
Topotecan for the treatment of recurrent or progressive central nervous system tumors - a pediatric oncology group phase II study.
Topics: Adult; Antineoplastic Agents; Central Nervous System Neoplasms; Child; Disease Progression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Magnetic Resonance Imaging; Neoplasm Recurrence, Local; Tomography, X-Ray Computed; Topotecan | 1999 |
Phase II study of topotecan plus cranial radiation for glioblastoma multiforme: results of Radiation Therapy Oncology Group 9513.
Topics: Aged; Antineoplastic Agents; Central Nervous System Neoplasms; Disease Progression; Disease-Free Survival; Female; Glioblastoma; Gliosarcoma; Humans; Male; Middle Aged; Time Factors; Topotecan; Treatment Outcome | 2002 |
9 other study(ies) available for topotecan and Central Nervous System Neoplasm
| Article | Year |
|---|---|
Combined high-dose intra-arterial and intrathecal chemotherapy for the treatment of a case of extraocular retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System Neoplasms; Child, Preschool; Humans; Infusions, Intra-Arterial; Injections, Spinal; Male; Melphalan; Retinal Neoplasms; Retinoblastoma; Topotecan | 2018 |
Successful Treatment of Relapsed Pediatric Acute Myeloid Leukemia Presenting as Central Nervous System Myeloid Sarcoma: A Single-Institution Case Series.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Child, Preschool; Clofarabine; Female; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Sarcoma, Myeloid; Thiotepa; Topotecan; Vinorelbine | 2020 |
The combination topotecan, temozolomide and dexamethasone associated with radiotherapy as treatment of central nervous system myeloma relapse.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Dacarbazine; Dexamethasone; Fatal Outcome; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Multiple Myeloma; Recurrence; Temozolomide; Topotecan | 2009 |
Topotecan and ifosfamide systemic chemotherapy for CNS involvement of solid tumors.
Topics: Aged; Antineoplastic Agents, Alkylating; Central Nervous System Neoplasms; Female; Humans; Ifosfamide; Karnofsky Performance Status; Male; Meningeal Carcinomatosis; Middle Aged; Topoisomerase I Inhibitors; Topotecan | 2011 |
Augmenting tumor sensitivity to topotecan by transient hypoxia.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Carcinoma, Small Cell; Cell Hypoxia; Cell Line, Tumor; Central Nervous System Neoplasms; Glioblastoma; Glucose Transporter Type 1; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Topotecan; Tumor Burden; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2005 |
Favorable response of intraommaya topotecan for leptomeningeal metastasis of neuroblastoma after intravenous route failure.
Topics: Antineoplastic Agents; Catheters, Indwelling; Central Nervous System Neoplasms; Child, Preschool; Combined Modality Therapy; Humans; Infusions, Intravenous; Injections, Spinal; Male; Meningeal Neoplasms; Neuroblastoma; Topoisomerase I Inhibitors; Topotecan | 2008 |
Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts.
Topics: Adult; Animals; Antineoplastic Agents; Camptothecin; Central Nervous System Neoplasms; Child; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Random Allocation; Time Factors; Topotecan; Transplantation, Heterologous | 1994 |
The potential of topoisomerase I inhibitors in the treatment of CNS malignancies: report of a synergistic effect between topotecan and radiation.
Topics: Antineoplastic Agents; Camptothecin; Cell Survival; Central Nervous System Neoplasms; Combined Modality Therapy; Enzyme Inhibitors; Glioma; Humans; Radiation-Sensitizing Agents; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured | 1996 |
The effect of increasing topotecan infusion from 30 minutes to 4 hours on the duration of exposure in cerebrospinal fluid.
Topics: Antineoplastic Agents; Area Under Curve; Breast Neoplasms; Central Nervous System Neoplasms; Chromatography, High Pressure Liquid; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Middle Aged; Topotecan | 2001 |