topotecan has been researched along with Cancer of Pancreas in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, W; Kai, GY; Li, L; Liu, XF; Liu, YQ; Peng, LZ; Xu, CR; Zhang, M; Zhang, ZJ; Zhu, LZ | 1 |
| Devriese, LA; Giantonio, BJ; Kerklaan, BM; Lane, S; Langenberg, M; Legenne, P; Lolkema, MP; Mergui-Roelvink, M; Mykulowycz, K; Nol-Boekel, A; Schellens, JH; Smith, DA; Stoebenau, J; Voest, EE; Wissel, P; Witteveen, PO | 1 |
| Antonijevic, MD; Forster, RE; Heaysman, CL; Lewis, AL; Lloyd, AW; Macfarlane, W; Phillips, GJ; Small, SA; Tang, Y | 1 |
| Bowyer, C; Forster, RE; Lewis, AL; Lloyd, AW; Macfarlane, W; Phillips, GJ; Tang, Y | 1 |
| Balsari, A; Carenini, N; De Cesare, M; Perego, P; Petrangolini, G; Pratesi, G; Tortoreto, M; Zunino, F | 1 |
| Beijnen, J; de Boer-Dennert, M; Hansen, H; Koier, I; Lund, B; Planting, A; Rosing, H; Verweij, J | 1 |
| Alexander, R; Amfoh, K; Engstrom, PF; Fox, S; Green, F; Kosierowski, R; Lusch, C; O'Dwyer, PJ; Raskay, B; Redei, I; Scher, RM | 1 |
| Donehower, RC; Grochow, LB; O'Reilly, S; Ord, S; Rowinsky, EK | 1 |
| Kono, A; Kumazawa, E; Shimazoe, T; Takiguchi, S; Tohgo, A | 1 |
| Adler, H; Buckley, M; Cho, J; Dar, K; Fry, D; Hochster, H; Kim, T; Liebes, L; Pease, D; Potmesil, M; Zeleniuch-Jacquotte, A | 1 |
| Broom, C; Fields, SZ; Fox, SC; Green, F; Kosierowski, R; Krebs, JB; O'Dwyer, PJ; Scher, RM; Simmonds, M; Stevenson, JP; Yao, KS | 1 |
6 trial(s) available for topotecan and Cancer of Pancreas
| Article | Year |
|---|---|
Phase I and pharmacological study of pazopanib in combination with oral topotecan in patients with advanced solid tumours.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Indazoles; Male; Maximum Tolerated Dose; Middle Aged; Ovarian Neoplasms; Pancreatic Neoplasms; Pyrimidines; Sulfonamides; Topotecan; Treatment Outcome; Young Adult | 2015 |
Phase I and pharmacokinetics study of topotecan, a new topoisomerase I inhibitor.
Topics: Adult; Aged; Alopecia; Antineoplastic Agents; Camptothecin; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasms; Pancreatic Neoplasms; Remission Induction; Topoisomerase I Inhibitors; Topotecan | 1993 |
Phase II trial of topotecan in advanced or metastatic adenocarcinoma of the pancreas.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasms; Topotecan | 1996 |
A phase II trial of topotecan in patients with previously untreated pancreatic cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Pancreatic Neoplasms; Topotecan | 1996 |
Pharmacodynamics of topoisomerase I inhibition: Western blot determination of topoisomerase I and cleavable complex in patients with upper gastrointestinal malignancies treated with topotecan.
Topics: Adenoma, Islet Cell; Antineoplastic Agents; Autoantibodies; Autoantigens; Biomarkers; Biopsy; Breast Neoplasms; Cell Line; DNA Topoisomerases, Type I; Endometrial Neoplasms; Esophageal Neoplasms; Female; Gastrointestinal Neoplasms; HeLa Cells; Humans; Lung Neoplasms; Nuclear Proteins; Ovarian Neoplasms; Pancreatic Neoplasms; Scleroderma, Systemic; Stomach Neoplasms; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured | 1998 |
Phase II trial of topotecan as a 21-day continuous infusion in patients with advanced or metastatic adenocarcinoma of the pancreas.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Follow-Up Studies; Hematologic Diseases; Humans; Infusions, Intravenous; Male; Middle Aged; Pancreatic Neoplasms; Survival Rate; Topotecan; Treatment Outcome | 1998 |
5 other study(ies) available for topotecan and Cancer of Pancreas
| Article | Year |
|---|---|
Anti-tumor effects and mechanism of a novel camptothecin derivative YCJ100.
Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Topoisomerases, Type I; Female; Humans; Liver Neoplasms; Mice; Molecular Docking Simulation; Pancreatic Neoplasms; Topoisomerase I Inhibitors; Topotecan; Xenograft Model Antitumor Assays | 2022 |
Comparison of DC Bead-irinotecan and DC Bead-topotecan drug eluting beads for use in locoregional drug delivery to treat pancreatic cancer.
Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Humans; Irinotecan; Pancreatic Neoplasms; Topotecan | 2010 |
Development of a combination drug-eluting bead: towards enhanced efficacy for locoregional tumour therapies.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Doxorubicin; Humans; Irinotecan; Liver Neoplasms; Mice; Mice, Nude; Pancreatic Neoplasms; Prostheses and Implants; Sirolimus; Topotecan; Xenograft Model Antitumor Assays | 2012 |
Combination of metronomic gimatecan and CpG-oligodeoxynucleotides against an orthotopic pancreatic cancer xenograft.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Line, Tumor; Female; Humans; Mice; Mice, Nude; Oligodeoxyribonucleotides; Pancreatic Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Topotecan; Xenograft Model Antitumor Assays | 2008 |
Antitumor effect of DX-8951, a novel camptothecin analog, on human pancreatic tumor cells and their CPT-11-resistant variants cultured in vitro and xenografted into nude mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; DNA Fragmentation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Irinotecan; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasm Proteins; Neoplasm Transplantation; Pancreatic Neoplasms; Prodrugs; Splenic Neoplasms; Topoisomerase I Inhibitors; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured | 1997 |