topotecan has been researched along with Cancer of Head in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klopfenstein, KJ; Ruymann, FB; Schuller, DE; Scott, S | 1 |
| Begg, AC; Bloom, G; Boulware, D; Calvin, DP; Eschrich, SA; Kelley, S; Lee, JH; Pramana, J; Rocha-Lima, C; Torres-Roca, JF; Yeatman, TJ; Zhang, H; Zhao, H | 1 |
| Haddad, RI; Van Echo, DA | 1 |
| Murphy, BA | 1 |
| Brown, JM; Cao, H; Choi, CY; Faix, JD; Giaccia, AJ; Koong, AC; Le, QT; Nelson, DW; Sunar-Reeder, B; Zhu, Y | 1 |
| Li, QY; Shao, JH; Xiang, Y; Yang, JZ | 1 |
| Ara, G; Boscia, RE; Holden, SA; Korbut, T; Teicher, BA | 1 |
| Heuser, A; Sauer, R | 1 |
| Ensley, JF; Lew, D; Rodriguez, GI; Schuller, D; Smith, RE; Taylor, SA | 1 |
| Robert, F; Soong, SJ; Wheeler, RH | 1 |
| Khattab, J; Urba, SG | 1 |
| Chen, AY; Choy, H; Rothenberg, ML | 1 |
| Burkey, B; Forastiere, A; Langer, C; Leong, T; Murphy, BA | 1 |
| Burkey, B; Cmelak, A; Douglas, S; Murphy, BA; Netterville, J; Shyr, Y; Smith, W | 1 |
5 review(s) available for topotecan and Cancer of Head
| Article | Year |
|---|---|
Topoisomerases in the treatment of metastatic or recurrent squamous carcinoma of the head and neck.
Topics: Camptothecin; Carcinoma, Squamous Cell; Clinical Trials as Topic; DNA Topoisomerases, Type I; Head and Neck Neoplasms; Humans; Irinotecan; Neoplasm Recurrence, Local; Topoisomerase I Inhibitors; Topotecan | 2005 |
[Topoisomerase I inhibitor with potential radiosensitizing effect].
Topics: Antineoplastic Agents; Brain Neoplasms; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Child; Clinical Trials as Topic; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Neoplasms; Ovarian Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage; Topoisomerase I Inhibitors; Topotecan | 1997 |
Chemotherapy in head and neck cancer. Overview of newer agents.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Docetaxel; Gemcitabine; Head and Neck Neoplasms; Humans; Organoplatinum Compounds; Paclitaxel; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Taxoids; Topotecan; Vinblastine; Vinorelbine | 1999 |
DNA topoisomerase I-targeting drugs as radiation sensitizers.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Cycle; Colonic Neoplasms; Combined Modality Therapy; DNA Damage; DNA Repair; DNA Topoisomerases, Type I; Enzyme Inhibitors; Female; Head and Neck Neoplasms; Humans; Irinotecan; Lung Neoplasms; Neoplasms; Ovarian Neoplasms; Radiation-Sensitizing Agents; Topotecan | 1999 |
Topoisomerase I inhibitors in the treatment of head and neck cancer.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Squamous Cell; Enzyme Inhibitors; Head and Neck Neoplasms; Humans; Irinotecan; Survival Analysis; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome | 2001 |
5 trial(s) available for topotecan and Cancer of Head
| Article | Year |
|---|---|
A gene expression model of intrinsic tumor radiosensitivity: prediction of response and prognosis after chemoradiation.
Topics: Aged; Aged, 80 and over; Algorithms; Antineoplastic Agents; Cell Line, Tumor; Esophageal Neoplasms; Female; Gene Expression; Head and Neck Neoplasms; Humans; Linear Models; Male; Middle Aged; Models, Genetic; Oligonucleotide Array Sequence Analysis; Prognosis; Prospective Studies; Radiation Tolerance; Rectal Neoplasms; Topotecan | 2009 |
Phase II study of docetaxel and topotecan combination chemotherapy in patients with advanced head and neck cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Synergism; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Survival Analysis; Taxoids; Topotecan | 2003 |
Evaluation of topotecan in patients with recurrent for metastatic squamous cell carcinoma of the head and neck. A phase II Southwest Oncology Group study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Topotecan | 1996 |
A phase II study of topotecan in patients with recurrent head and neck cancer. Identification of an active new agent.
Topics: Adult; Aged; Anemia; Antineoplastic Agents; Camptothecin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neutropenia; Quality of Life; Remission Induction; Survival Analysis; Topotecan | 1997 |
Lack of efficacy of topotecan in the treatment of metastatic or recurrent squamous carcinoma of the head and neck: an Eastern Cooperative Oncology Group Trial (E3393).
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Topotecan | 2001 |
4 other study(ies) available for topotecan and Cancer of Head
| Article | Year |
|---|---|
Prolonged survival with continuous infusion topotecan: a report of 2 cases.
Topics: Adolescent; Antineoplastic Agents; Carcinoma, Hepatocellular; Child; Child, Preschool; Female; Head and Neck Neoplasms; Histiocytoma, Malignant Fibrous; Humans; Infusions, Intravenous; Liver Neoplasms; Neoplasms, Second Primary; Palliative Care; Survival; Topotecan | 2008 |
A noninvasive approach for assessing tumor hypoxia in xenografts: developing a urinary marker for hypoxia.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Chorionic Gonadotropin, beta Subunit, Human; Colorectal Neoplasms; DNA-Binding Proteins; Flavonoids; Genes, Reporter; Genetic Vectors; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred BALB C; Mice, Inbred SENCAR; Neoplasm Transplantation; Nuclear Proteins; Piperidines; Topotecan; Transcription Factors; Transfection; Transplantation, Heterologous | 2005 |
[Therapeutic and adverse effects of topotecan combined with cisplatin for treatment of advanced squamous cell lung cancer and head and neck cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Topotecan; Treatment Outcome; Young Adult | 2008 |
Interaction of topoisomerase I inhibitors with radiation in cis-diamminedichloroplatinum(II)-sensitive and -resistant cells in vitro and in the FSAIIC fibrosarcoma in vivo.
Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Resistance; Fibrosarcoma; Head and Neck Neoplasms; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred C3H; Topotecan; Tumor Cells, Cultured | 1993 |