Page last updated: 2024-08-24

topotecan and Bone Cancer

topotecan has been researched along with Bone Cancer in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's11 (64.71)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buchdunger, E; Germain, GS; Harwood, FC; Houghton, PJ; Schuetz, JD; Stewart, CF; Traxler, P1
Agaoglu, FY; Cakir, FB; Darendeliler, E; Gorgun, O; Kebudi, R1
Bond, MC; Felgenhauer, JL; Femino, JD; Gorlick, R; Krailo, MD; Laack, NN; Marina, N; Mascarenhas, L; Meyer, J; Ranganathan, S; Villaluna, D; Womer, RB1
Bohr, VA; Christmann, M; Gestrich, C; Kaina, B; Roos, WP; Tomicic, MT1
Cassier, P; Chapet, O; Chekrine, T; De Bari, B; Kulisa, M; Mornex, F1
Deméocq, F; Halle, P; Isfan, F; Kanold, J; Kelly, A; Lang, P; Marabelle, A; Merlin, E; Paillard, C; Rochette, E; Tchirkov, A1
Abboud, M; Eid, T; El-Solh, H; Farhat, R; Feghaly, J; Khoury, NJ; Muwakkit, S; Raad, R; Saab, R1
Beriwal, S; Garcia-Young, JA; Singh, S1
Davidson, NE; Gradishar, WJ; Kennedy, MJ; Lord, RS; O'Neill, A; Stewart, JA; Wolff, AC; Wood, WC1
Bernstein, ML; Devidas, M; Dickman, PS; Dubowy, R; Gebhardt, M; Goorin, A; Grier, HE; Lafreniere, D; Link, MP; Meyers, PA; Nicholas, R; Perlman, EJ; Souid, AK; Stine, K; Wainer, IW1
Hunold, A; Jürgens, H; Liebscher, C; Paulussen, M; Ranft, A; Weddeling, N1
Dethling, J; Fink, T; Hans, K; Koschel, G; Lorenz, R; Mueller, C; Schade-Brittinger, C; Schroeder, H; Seifart, U; Wolf, M1
Al Harbi, T; Al-Faris, N; Doyle, J; Gassas, A; Goia, C; Pappo, A1
Breitfeld, PP; Chen, Z; Drachtman, R; Greffe, B; Healey, J; Krailo, M; Meyers, PA; Nachman, J; Nadel, H; Reaman, GH; Sato, JK; Seibel, NL1
DeClerck, YA; Groshen, SG; Moats, RA; Nelson, MD; Peng, H; Reynolds, CP; Sohara, Y; Ye, W1
Adamson, PC; Balis, FM; Berg, SL; Blaney, SM; Bleyer, WA; Gillespie, A; Krailo, MD; Needle, MN; Poplack, DG; Reaman, GH; Sato, JK1
Bernstein, ML; Harris, MB; Hayashi, R; Kepner, JL; Saylors, RL; Stine, KC; Sullivan, J; Vietti , TJ; Wall, DA1

Reviews

1 review(s) available for topotecan and Bone Cancer

ArticleYear
[Small cell neuroendocrine carcinoma of the bladder: A case report and review of the literature].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2011, Volume: 15, Issue:3

    Topics: Acute Kidney Injury; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Carcinoma in Situ; Carcinoma, Neuroendocrine; Carcinoma, Transitional Cell; Combined Modality Therapy; Emergencies; Etoposide; Humans; Lymphatic Irradiation; Lymphatic Metastasis; Male; Neoadjuvant Therapy; Neoplasms, Multiple Primary; Prognosis; Prostatic Hyperplasia; Topoisomerase I Inhibitors; Topotecan; Urinary Bladder Neoplasms

2011

Trials

7 trial(s) available for topotecan and Bone Cancer

ArticleYear
Single-agent topotecan as first-line chemotherapy in women with metastatic breast cancer: final results of eastern cooperative oncology group trial E8193.
    Clinical breast cancer, 2005, Volume: 6, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Bone Neoplasms; Breast Neoplasms; DNA Topoisomerases, Type I; Doxorubicin; Enzyme Inhibitors; Female; Humans; Infusions, Intravenous; Middle Aged; Soft Tissue Neoplasms; Topotecan

2005
Intensive therapy with growth factor support for patients with Ewing tumor metastatic at diagnosis: Pediatric Oncology Group/Children's Cancer Group Phase II Study 9457--a report from the Children's Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jan-01, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Amifostine; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Male; Sarcoma, Ewing; Topotecan

2006
Topotecan and cyclophosphamide in patients with refractory or relapsed Ewing tumors.
    Pediatric blood & cancer, 2006, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Disease Progression; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Recurrence; Remission Induction; Salvage Therapy; Sarcoma, Ewing; Survival Rate; Topotecan; Treatment Outcome

2006
Randomised phase II study comparing topotecan/carboplatin administration for 5 versus 3 days in the treatment of extensive-stage small-cell lung cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Small Cell; Central Nervous System Neoplasms; Cisplatin; Female; Humans; Infusions, Intravenous; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Survival Rate; Time Factors; Topotecan; Treatment Outcome

2007
Upfront window trial of topotecan in previously untreated children and adolescents with poor prognosis metastatic osteosarcoma: children's Cancer Group (CCG) 7943.
    Cancer, 2007, Apr-15, Volume: 109, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Female; Humans; Lung Neoplasms; Maximum Tolerated Dose; Osteosarcoma; Prognosis; Survival Analysis; Survival Rate; Topotecan

2007
Phase II trial of topotecan administered as 72-hour continuous infusion in children with refractory solid tumors: a collaborative Pediatric Branch, National Cancer Institute, and Children's Cancer Group Study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant; Infusions, Intravenous; Male; Neoplasms; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Osteosarcoma; Rhabdomyosarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Topotecan

1998
Cyclophosphamide plus topotecan in children with recurrent or refractory solid tumors: a Pediatric Oncology Group phase II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Aug-01, Volume: 19, Issue:15

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Infant; Infusions, Intravenous; Male; Neoplasm Recurrence, Local; Neoplasms; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma; Sarcoma, Ewing; Topotecan

2001

Other Studies

9 other study(ies) available for topotecan and Bone Cancer

ArticleYear
Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro.
    Cancer research, 2004, Apr-01, Volume: 64, Issue:7

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzamides; Bone Neoplasms; Camptothecin; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Imatinib Mesylate; Irinotecan; Neoplasm Proteins; Osteosarcoma; Piperazines; Pyrimidines; Topotecan

2004
A modified protocol with vincristine, topotecan, and cyclophosphamide for recurrent/progressive ewing sarcoma family tumors.
    Pediatric hematology and oncology, 2013, Volume: 30, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Disease Progression; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Remission Induction; Sarcoma, Ewing; Topotecan; Vincristine

2013
Pilot Study of Adding Vincristine, Topotecan, and Cyclophosphamide to Interval-Compressed Chemotherapy in Newly Diagnosed Patients With Localized Ewing Sarcoma: A Report From the Children's Oncology Group.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Male; Pilot Projects; Sarcoma, Ewing; Soft Tissue Neoplasms; Topotecan; Vincristine

2016
WRN protects against topo I but not topo II inhibitors by preventing DNA break formation.
    DNA repair, 2008, Dec-01, Volume: 7, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Bone Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Survival; Colony-Forming Units Assay; DNA Breaks; DNA Repair; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Enzyme Inhibitors; Etoposide; Exodeoxyribonucleases; Histones; Humans; Osteosarcoma; RecQ Helicases; RNA, Small Interfering; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured; Werner Syndrome Helicase

2008
NK cell immunotherapy for high-risk neuroblastoma relapse after haploidentical HSCT.
    Pediatric blood & cancer, 2012, Volume: 59, Issue:4

    Topics: Adrenal Gland Neoplasms; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Bone Marrow Neoplasms; Bone Neoplasms; Child; Combined Modality Therapy; Dacarbazine; Doublecortin Domain Proteins; Haplotypes; Hematopoietic Stem Cell Transplantation; Homeodomain Proteins; Humans; Immunotherapy; Interleukin-2; Killer Cells, Natural; Male; Microtubule-Associated Proteins; Neoplasm, Residual; Neuroblastoma; Neuropeptides; Remission Induction; Temozolomide; Topotecan; Transcription Factors; Transplantation, Homologous; Tyrosine 3-Monooxygenase

2012
Cyclophosphamide and topotecan as first-line salvage therapy in patients with relapsed ewing sarcoma at a single institution.
    Journal of pediatric hematology/oncology, 2013, Volume: 35, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Male; Neoplasm Recurrence, Local; Retrospective Studies; Salvage Therapy; Sarcoma, Ewing; Topotecan; Treatment Outcome; Young Adult

2013
Tumor lysis syndrome in extensive-stage small-cell lung cancer.
    American journal of clinical oncology, 2002, Volume: 25, Issue:5

    Topics: Aged; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Small Cell; Enzyme Inhibitors; Fatal Outcome; Female; Humans; Lung Neoplasms; Topotecan; Tumor Lysis Syndrome

2002
Does consolidation with autologous stem cell transplantation improve the outcome of children with metastatic or relapsed Ewing sarcoma?
    Pediatric blood & cancer, 2007, Volume: 49, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Carboplatin; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Epirubicin; Etoposide; Follow-Up Studies; Humans; Ifosfamide; Infection Control; Kaplan-Meier Estimate; Melphalan; Neoplasm Recurrence, Local; Peripheral Blood Stem Cell Transplantation; Postoperative Care; Retrospective Studies; Risk; Salvage Therapy; Sarcoma, Ewing; Topotecan; Transplantation Conditioning; Transplantation, Autologous; Treatment Failure; Vincristine

2007
The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation.
    Cancer research, 2007, Oct-01, Volume: 67, Issue:19

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Density Conservation Agents; Bone Neoplasms; Caspase 3; Cell Growth Processes; Cell Survival; Cyclophosphamide; Diphosphonates; Enzyme Activation; Humans; Imidazoles; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuroblastoma; Osteoclasts; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; ras Proteins; Topotecan; Xenograft Model Antitumor Assays; Zoledronic Acid

2007