topotecan has been researched along with Blood Diseases in 35 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (11.43) | 18.2507 |
2000's | 27 (77.14) | 29.6817 |
2010's | 4 (11.43) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Kraal, KC; Tytgat, GA; van Dalen, EC; Van Eck-Smit, BL | 1 |
Altman, JK; Broun, ER; Carroll, MP; Karp, JE; Kaufmann, SH; Ketterling, RP; Lazarus, HM; Litzow, MR; Luger, SM; Paietta, EM; Pratz, KW; Rowe, JM; Rybka, WB; Tallman, MS; Tun, HW; Wang, XV; Zhang, Y | 1 |
Billups, CA; Brennan, RC; Hoehn, ME; Mao, S; Qaddoumi, I; Rodriguez-Galindo, C; Stewart, CF; Wilson, MW; Wu, J | 1 |
Ross, HJ; Seung, SK | 1 |
Bae, DS; Choi, CH; Kim, BG; Kim, MK; Kim, TJ; Lee, JH; Lee, JW; Lee, YY; Park, HS; Song, TJ | 1 |
Fukuoka, M; Furuse, K; Hasegawa, K; Hino, M; Horikoshi, N; Kanamaru, R; Kimura, I; Kinoshita, H; Kobayashi, K; Niitani, H; Noda, K; Taguchi, T; Takeuchi, K; Yoneda, S | 1 |
Deppermann, M; Kaubitsch, S; Keppler, U; Korfel, A; Oehm, C; Thiel, E; von Pawel, J | 1 |
Gutierrez, M; Lhomme, C; Pautier, P | 1 |
Douillard, JY; Schiller, J | 1 |
Apuzzo, L; Chang, L; Concha, M; Dupont, B; Ernst, T; Fish, D; Goodkin, K; McGuire, D; Pailloux, G; Poncelet, H; Post, MJ; Royal, W; Singer, E | 1 |
Armstrong, DK | 1 |
Catapano, CV; Freeman, KD; Green, MR; Mushtaq, C; Oakhill, G; Pacheco, D; Rocha Lima, CM; Sherman, CA | 1 |
Adams, N; Cunningham, CC; MacEachern, JB; Nemunaitis, J; Paulson, AS; Rich, D; Ruxer, RL; Vukelja, S | 1 |
Buller, R; Crawford, J; Garst, J; Lane, S | 1 |
Bookman, MA; Fracasso, PM; McMeekin, DS | 1 |
Anderson, E; Andrews, C; Bjurstrom, T; Blackwell, S; Campagna, L; Crawford, J; Garst, J; Herndon, JE; Maravich-May, D; Padilla, K; Shafman, T | 1 |
Armstrong, DK; Bookman, MA; Bristow, RE; McGuire, W; Schilder, JM | 1 |
Chang, J; Cheon, SH; Cho, BC; Choi, HJ; Jung, JY; Kim, JH; Kim, SK; Shin, SJ; Sohn, JH | 1 |
Fels, C; Hau, P; Janssen, G; Liebeskind, AK; Peters, O; Sauerbrey, A; Suttorp, M; Wagner, S; Wolff, JE | 1 |
Chamorey, E; Creisson, A; Ferrero, JM; Hebert, C; Largillier, R; Lesbats, G; Mari, V; Novo, C; Valenza, B | 1 |
Beijnen, JH; Dubbelman, AC; Groot, Y; Herben, VM; Mandjes, IA; ten Bokkel Huinink, WW; van Gortel-van Zomeren, DM | 1 |
Burris, H; Eckardt, JR; Fields, S; Gerrits, CJ; Hudson, I; Loos, WJ; Planting, AS; Rodriguez, GI; Schellens, JH; van Beurden, V; van der Burg, ME; Verweij, J; Von Hoff, DD | 1 |
Broom, C; Fields, SZ; Fox, SC; Green, F; Kosierowski, R; Krebs, JB; O'Dwyer, PJ; Scher, RM; Simmonds, M; Stevenson, JP; Yao, KS | 1 |
Burris, H; Fields, S; Gerrits, CJ; Hudson, I; Loos, WJ; Planting, AS; Rodriguez, GI; Schellens, JH; van Beurden, V; van den Burg, ME; Verweij, J; von Hoff, DD | 1 |
Brown, JV; Dillman, RA; Drescher, CW; Karlan, BY; Micha, JP; Peters, WA; Rettenmaier, MA; Smith, MR | 1 |
Beckman, RA; Gore, M; Hearn, S; Lane, SR; Ross, G; Rustin, G; Schüller, J | 1 |
Allen, D; Davison, J; Gates, P; Neesham, D; Planner, R; Prince, HM; Quinn, M; Rischin, D | 1 |
Beckman, RA; Clarke-Pearson, DL; DeWitte, MH; Fields, SZ; Hanjani, P; Iveson, T; Kristensen, G; Lane, SR; Malfetano, JH; Ross, GA; Van Le, L; Whitney, CW | 1 |
Astre, C; Boucaud, M; Bressolle, F; Culine, S; Cupissol, D; Pinguet, F; Poujol, S; Romieu, G | 1 |
Beckman, RA; Calvert, H; Carmichael, J; Clarke-Pearson, D; Fields, SZ; Gore, M; Malfetano, J; Oza, A; Ross, G; Rustin, G | 1 |
Boothby, R; DeCesare, S; Fiorica, J; Grendys, E; Hoffman, M; Holloway, R; LaPolla, J; Ndubisi, B; Orr, J; Patel, J | 1 |
Avila, A; Dunton, CJ; King, SA; Neufeld, J; Perez, G; Tolosa, J; Underhill, K | 1 |
Hanjani, P; Nolte, S; Shahin, MS | 1 |
Boddy, AV; Calvert, AH; Calvert, PM; Fishwick, K; Griffin, MJ; Ross, GA; Schätzlein, A; Simpson, AB; Sludden, JA; Twelves, CJ; Wheatley, A; Wilson, P | 1 |
Crane, MM; Hunter, JE; Puls, LE | 1 |
3 review(s) available for topotecan and Blood Diseases
Article | Year |
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Iodine-131-meta-iodobenzylguanidine therapy for patients with newly diagnosed high-risk neuroblastoma.
Topics: 3-Iodobenzylguanidine; Adolescent; Antineoplastic Agents; Bone Marrow; Child; Child, Preschool; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Infant; Neuroblastoma; Observational Studies as Topic; Radiopharmaceuticals; Thyroid Diseases; Topotecan | 2017 |
[Gemicitabine in the treatment of epithelial ovarian cancer].
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Neoplasm; Female; Gemcitabine; Hematologic Diseases; Humans; Multicenter Studies as Topic; Organoplatinum Compounds; Ovarian Neoplasms; Paclitaxel; Palliative Care; Prodrugs; Remission Induction; Topotecan; Treatment Outcome; Vinblastine; Vinorelbine | 2002 |
Topotecan dosing guidelines in ovarian cancer: reduction and management of hematologic toxicity.
Topics: Antineoplastic Agents; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Incidence; Ovarian Neoplasms; Practice Guidelines as Topic; Receptors, Colony-Stimulating Factor; Recurrence; Risk Factors; Topotecan | 2004 |
25 trial(s) available for topotecan and Blood Diseases
Article | Year |
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A randomized trial of three novel regimens for recurrent acute myeloid leukemia demonstrates the continuing challenge of treating this difficult disease.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Disease-Free Survival; Etoposide; Female; Flavonoids; Follow-Up Studies; Gastrointestinal Diseases; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Recurrence; Remission Induction; Salvage Therapy; Sirolimus; Topotecan; Tumor Lysis Syndrome | 2019 |
Phase II trial of combined modality therapy with concurrent topotecan plus radiotherapy followed by consolidation chemotherapy for unresectable stage III and selected stage IV non-small-lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Docetaxel; Etoposide; Female; Follow-Up Studies; Hematologic Diseases; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pilot Projects; Taxoids; Topotecan | 2009 |
Phase I studies of nogitecan hydrochloride for Japanese.
Topics: Adult; Aged; Antineoplastic Agents; Blood Cell Count; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Gastrointestinal Diseases; Half-Life; Hematologic Diseases; Humans; Japan; Maximum Tolerated Dose; Middle Aged; Neoplasms; Topoisomerase I Inhibitors; Topotecan | 2002 |
Response to topotecan of symptomatic brain metastases of small-cell lung cancer also after whole-brain irradiation. a multicentre phase II study.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Small Cell; Cranial Irradiation; Disease Progression; Hematologic Diseases; Humans; Infusions, Intravenous; Lung Neoplasms; Middle Aged; Prospective Studies; Survival Analysis; Topotecan | 2002 |
ZD0473 combined with other chemotherapeutic agents for the treatment of solid malignancies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Female; Hematologic Diseases; Humans; Infusions, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Organoplatinum Compounds; Topotecan; Treatment Outcome; Vinblastine; Vinorelbine | 2002 |
Topotecan in the treatment of acquired immunodeficiency syndrome-related progressive multifocal leukoencephalopathy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Brain; CD4 Lymphocyte Count; Cohort Studies; Drug Administration Schedule; Enzyme Inhibitors; Female; Hematologic Diseases; HIV-1; Humans; Karnofsky Performance Status; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Middle Aged; RNA, Viral; Topoisomerase I Inhibitors; Topotecan; Treatment Outcome; Viral Load | 2003 |
Phase I trial of topotecan in combination with gemcitabine in refractory solid tumor patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Deoxycytidine; Dose-Response Relationship, Drug; Female; Gemcitabine; Hematologic Diseases; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Prospective Studies; Topotecan; Treatment Outcome | 2004 |
Sequence dependence of hematologic toxicity using carboplatin and topotecan for primary therapy of advanced epithelial ovarian cancer: a phase I study of the Gynecologic Oncology Group.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cohort Studies; Drug Administration Schedule; Epithelial Cells; Female; Hematologic Diseases; Humans; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Topotecan | 2006 |
A phase I study of dose-dense topotecan given upfront to standard therapy in patients with small cell lung cancer.
Topics: Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Karnofsky Performance Status; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Staging; Radiotherapy, Adjuvant; Remission Induction; Survival Rate; Topotecan; Treatment Outcome | 2006 |
A phase I study of paclitaxel, topotecan, cisplatin and Filgrastim in patients with newly diagnosed advanced ovarian epithelial malignancies: a Gynecologic Oncology Group study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cohort Studies; Dose-Response Relationship, Drug; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Paclitaxel; Recombinant Proteins; Topotecan | 2007 |
Pegylated-liposomal doxorubicin and oral topotecan in eight children with relapsed high-grade malignant brain tumors.
Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Child; Child, Preschool; Choroid Plexus Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Eruptions; Glioblastoma; Hematologic Diseases; Humans; Neoplasm Recurrence, Local; Polyethylene Glycols; Recurrence; Retrospective Studies; Stomatitis; Topotecan; Treatment Outcome | 2008 |
Phase I and pharmacological study of sequential intravenous topotecan and oral etoposide.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Etoposide; Female; Hematologic Diseases; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Topotecan | 1997 |
Oral topotecan given once or twice daily for ten days: a phase I pharmacology study in adult patients with solid tumors.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Male; Middle Aged; Neoplasms; Topotecan | 1998 |
Phase II trial of topotecan as a 21-day continuous infusion in patients with advanced or metastatic adenocarcinoma of the pancreas.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Follow-Up Studies; Hematologic Diseases; Humans; Infusions, Intravenous; Male; Middle Aged; Pancreatic Neoplasms; Survival Rate; Topotecan; Treatment Outcome | 1998 |
Five days of oral topotecan (Hycamtin), a phase I and pharmacological study in adult patients with solid tumours.
Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Agents; Breast Neoplasms; Colorectal Neoplasms; Fatigue; Female; Hematologic Diseases; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Topotecan; Treatment Outcome | 1998 |
A phase I trial of a 3-day topotecan Q 21 days for recurrent epithelial cancers of the ovary, fallopian tube, and peritoneum.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Epithelium; Fallopian Tube Neoplasms; Female; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Infusions, Intravenous; Klebsiella Infections; Klebsiella pneumoniae; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Peritoneal Neoplasms; Sleep Stages; Topotecan | 2000 |
Topotecan given as a 21-day infusion in the treatment of advanced ovarian cancer.
Topics: Abdominal Pain; Adult; Aged; Alopecia; Antineoplastic Agents; Diarrhea; Fatigue; Female; Hematologic Diseases; Humans; Infusions, Intravenous; Middle Aged; Nausea; Ovarian Neoplasms; Survival Analysis; Survival Rate; Time Factors; Topotecan; Treatment Outcome; Vomiting | 2001 |
Repetitive high-dose topotecan, carboplatin, and paclitaxel with peripheral blood progenitor cell support in previously untreated ovarian cancer: results of a Phase I study.
Topics: Adult; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Blood Component Removal; Carboplatin; Combined Modality Therapy; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Fallopian Tube Neoplasms; Female; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Middle Aged; Ovarian Neoplasms; Paclitaxel; Peritoneal Neoplasms; Topotecan | 2001 |
Oral topotecan as single-agent second-line chemotherapy in patients with advanced ovarian cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Drug Resistance, Neoplasm; Female; Hematologic Diseases; Humans; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Ovarian Neoplasms; Survival Rate; Topotecan | 2001 |
A randomised trial of oral versus intravenous topotecan in patients with relapsed epithelial ovarian cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Ovarian Neoplasms; Tomography, X-Ray Computed; Topotecan | 2002 |
Phase II trial of topotecan and cisplatin in persistent or recurrent squamous and nonsquamous carcinomas of the cervix.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Middle Aged; Neoplasm Recurrence, Local; Topotecan; Uterine Cervical Neoplasms | 2002 |
Phase I study of topotecan and radiation therapy in advanced cervical cancer.
Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Hematologic Diseases; Humans; Middle Aged; Radiation-Sensitizing Agents; Topotecan; Uterine Cervical Neoplasms | 2002 |
Phase II evaluation of 3-day topotecan with cyclophosphamide in the treatment of recurrent ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease-Free Survival; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Topotecan | 2002 |
Topotecan in combination with carboplatin: phase I trial evaluation of two treatment schedules.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Hematologic Diseases; Humans; Infusions, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Survival Rate; Topotecan | 2002 |
Effect of topotecan infusion duration on hematologic toxicity in recurrent ovarian carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Infusions, Intravenous; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Prospective Studies; Time Factors; Topotecan; Treatment Outcome | 2002 |
7 other study(ies) available for topotecan and Blood Diseases
Article | Year |
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Ocular Salvage and Vision Preservation Using a Topotecan-Based Regimen for Advanced Intraocular Retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Diarrhea; Disease-Free Survival; Eye Enucleation; Female; Follow-Up Studies; Hematologic Diseases; Humans; Infant; Male; Radiotherapy; Retinoblastoma; Salvage Therapy; Survival Rate; Topotecan; Vincristine; Vision Disorders; Visual Acuity | 2017 |
Sequence-dependent hematologic side effects of topotecan and cisplatin in persistent or recurrent cervical cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Hematologic Diseases; Humans; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Topotecan; Uterine Cervical Neoplasms | 2010 |
A phase I study of sequential administration of escalating doses of intravenous paclitaxel, oral topotecan, and fixed-dose oral etoposide in patients with solid tumors.
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; DNA Topoisomerases, Type I; Drug Administration Schedule; Etoposide; Female; Hematologic Diseases; Humans; Infusions, Intravenous; Lymphocytes; Male; Middle Aged; Neoplasms; Paclitaxel; Topotecan | 2004 |
Topotecan in the treatment of elderly patients with relapsed small-cell lung cancer.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Hematologic Diseases; Humans; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Retrospective Studies; Survival Analysis; Topotecan; Treatment Outcome | 2005 |
Combination of topotecan and etoposide as a salvage treatment for patients with recurrent small cell lung cancer following irinotecan and platinum first-line chemotherapy.
Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Combined Modality Therapy; Endpoint Determination; Etoposide; Female; Hematologic Diseases; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Patient Compliance; Salvage Therapy; Topotecan | 2008 |
Haematological evaluation of weekly therapy with topotecan for the treatment of recurrent ovarian cancer resistant to platinum-based therapy.
Topics: Adenocarcinoma, Clear Cell; Adenocarcinoma, Mucinous; Aged; Aged, 80 and over; Antineoplastic Agents; Cohort Studies; Cystadenocarcinoma, Serous; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Endometrial Neoplasms; Female; Hematologic Diseases; Humans; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Ovarian Neoplasms; Retrospective Studies; Survival Rate; Topotecan; Treatment Outcome | 2007 |
Salivary and plasma pharmacokinetics of topotecan in patients with metastatic epithelial ovarian cancer.
Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Female; Hematologic Diseases; Humans; Infusions, Intravenous; Middle Aged; Ovarian Neoplasms; Saliva; Topotecan | 2001 |