Compounds > topotecan
Page last updated: 2024-08-24

topotecan and Angelman Syndrome

topotecan has been researched along with Angelman Syndrome in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ach, RA; Adams, S; Chédin, F; Coulson, RL; Crary, FK; Gonzales, ML; LaSalle, JM; Powell, WT; Tsang, P; Wong, SS; Yamada, NA; Yasui, DH1
Allen, JA; Bridges, AS; Chen, X; Dutton, JW; Huang, HS; Jin, J; King, IF; Lee, HM; Mabb, AM; Miriyala, J; Philpot, BD; Roth, BL; Sciaky, N; Taylor-Blake, B; Zylka, MJ1
Miller, G1
Rosania, K1

Other Studies

4 other study(ies) available for topotecan and Angelman Syndrome

ArticleYear
R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Aug-20, Volume: 110, Issue:34

    Topics: Angelman Syndrome; Animals; Chromatin; Chromatin Immunoprecipitation; Chromosomes, Human, Pair 15; Gene Expression Regulation; Gene Silencing; Genetic Loci; Genomic Imprinting; HEK293 Cells; Humans; Immunoblotting; In Situ Hybridization, Fluorescence; Locus Control Region; Mice; Mice, Knockout; Neurons; Prader-Willi Syndrome; Real-Time Polymerase Chain Reaction; RNA, Antisense; RNA, Small Nucleolar; snRNP Core Proteins; Statistics, Nonparametric; Topotecan; Ubiquitin-Protein Ligases

2013
Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons.
    Nature, 2011, Dec-21, Volume: 481, Issue:7380

    Topics: Alleles; Angelman Syndrome; Animals; Cells, Cultured; Cerebral Cortex; Drug Evaluation, Preclinical; Fathers; Female; Gene Silencing; Genomic Imprinting; Male; Mice; Mice, Inbred C57BL; Mothers; Neurons; Small Molecule Libraries; Topoisomerase Inhibitors; Topotecan; Ubiquitin-Protein Ligases

2011
Neurodevelopmental disorders. New hope for a devastating neurological disorder.
    Science (New York, N.Y.), 2011, Dec-23, Volume: 334, Issue:6063

    Topics: Angelman Syndrome; Animals; Brain; Camptothecin; Drug Evaluation, Preclinical; Gene Expression Regulation; Genetic Therapy; Humans; Irinotecan; Mice; Neurons; Topotecan; Transcriptional Activation; Ubiquitin-Protein Ligases

2011
Silenced genes turned on to treat Angelman's syndrome.
    Lab animal, 2012, Jan-20, Volume: 41, Issue:2

    Topics: Angelman Syndrome; Animals; Brain; Gene Silencing; Humans; Mice; Topotecan; Ubiquitin-Protein Ligases

2012