Page last updated: 2024-08-24

topotecan and Adverse Drug Event

topotecan has been researched along with Adverse Drug Event in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (33.33)29.6817
2010's6 (50.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Chen, M; Cui, W; Wan, Z; Yang, H; Zhang, X; Zhao, B1
Goyal, P; Kochhar, S; Narang, S; Pandey, AK; Sindhu, M1
Horita, N; Inoue, M; Kaneko, T; Kudo, M; Nagai, K; Nagakura, H; Nakashima, K; Sato, T; Shibata, Y; Shinkai, M; Tashiro, K; Tsukahara, T; Ushio, R; Watanabe, H; Yamamoto, M1
Kobos, R; Shukla, N; Steinherz, L; Steinherz, PG1
Conkling, P; Fitzgibbons, JF; Galsky, MD; Jotte, R; Klein, L; McNally, R; Oliver, JW; Renschler, MF; Reynolds, C1
Carter, JS; Downs, LS1
Jafari, M; Kislukhin, G; Long, AD; Murphy, ML1
Huber, RM; Kaubitzsch, S; Lane, S; Lilenbaum, RC; Masters, G; Treat, J; Wissel, P1
Benvenuti, M; Bhatt, MS; Gammon, DC; Glantz, MJ; Tran, L; Van Horn, A1
Baggstrom, MQ; Fracasso, PM; Govindan, R; Lim, WT; Read, W1

Reviews

1 review(s) available for topotecan and Adverse Drug Event

ArticleYear
Topotecan for Relapsed Small-cell Lung Cancer: Systematic Review and Meta-Analysis of 1347 Patients.
    Scientific reports, 2015, Oct-21, Volume: 5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Humans; Neoplasm Recurrence, Local; Small Cell Lung Carcinoma; Topotecan

2015

Trials

3 trial(s) available for topotecan and Adverse Drug Event

ArticleYear
Randomized phase II trial of single-agent amrubicin or topotecan as second-line treatment in patients with small-cell lung cancer sensitive to first-line platinum-based chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jan-20, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Agents; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Intention to Treat Analysis; Lung Neoplasms; Male; Middle Aged; Neutropenia; Small Cell Lung Carcinoma; Survival Analysis; Thrombocytopenia; Topoisomerase I Inhibitors; Topotecan; United States

2011
A prospective clinical trial of lenalidomide with topotecan in women with advanced epithelial ovarian carcinoma.
    International journal of clinical oncology, 2011, Volume: 16, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lenalidomide; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Neutropenia; Ovarian Neoplasms; Thalidomide; Topotecan

2011
A Phase I trial of weekly docetaxel and topotecan for solid tumors.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Risk Factors; Taxoids; Topotecan; Treatment Outcome

2008

Other Studies

8 other study(ies) available for topotecan and Adverse Drug Event

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
A real-world data analysis of topotecan in the FDA Adverse Event Reporting System (FAERS) database.
    Expert opinion on drug metabolism & toxicology, 2023, Volume: 19, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Data Analysis; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Topotecan; United States; United States Food and Drug Administration

2023
Adverse drug reaction after intravitreal injection of topotecan.
    Indian journal of ophthalmology, 2020, Volume: 68, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug-Related Side Effects and Adverse Reactions; Humans; Intravitreal Injections; Retinal Neoplasms; Retinoblastoma; Topotecan

2020
Remission re-induction chemotherapy with clofarabine, topotecan, thiotepa, and vinorelbine for patients with relapsed or refractory leukemia.
    Pediatric blood & cancer, 2010, Volume: 54, Issue:5

    Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Thiotepa; Topotecan; Vinblastine; Vinorelbine

2010
Chemotherapy-induced toxicity is highly heritable in Drosophila melanogaster.
    Pharmacogenetics and genomics, 2012, Volume: 22, Issue:4

    Topics: Animals; Carboplatin; Deoxycytidine; Dose-Response Relationship, Drug; Drosophila melanogaster; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Female; Fertility; Floxuridine; Gemcitabine; High-Throughput Screening Assays; Humans; Methotrexate; Mitomycin; Models, Animal; Neoplasms; Topotecan

2012
Topotecan therapy in patients with relapsed small-cell lung cancer and poor performance status.
    Clinical lung cancer, 2006, Volume: 8, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Small Cell; Clinical Trials as Topic; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Male; Middle Aged; Recurrence; Retrospective Studies; Survival Rate; Topotecan; Treatment Outcome

2006
Intrathecal topotecan in adult patients with neoplastic meningitis.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2006, Nov-01, Volume: 63, Issue:21

    Topics: Antineoplastic Agents; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Injections, Spinal; Male; Medical Audit; Meningeal Neoplasms; Middle Aged; Retrospective Studies; Topotecan; Treatment Outcome

2006