topiramate and Sensation-Disorders

To report palinopsia as a possible side effect of topiramate.. Case series and review of the literature.. Nine patients in our series, and 4 previously reported patients, who developed palinopsia while on topiramate, are reviewed. All patients were women, and comorbidities included migraine, idiopathic intracranial hypertension, and bulimia nervosa. Palinopsia resolved in 8 patients after stopping or decreasing the dose of topiramate. The lowest dose of topiramate causing palinopsia was 25 mg twice a day. More than half of our patients reported exacerbation of visual disturbance in early morning or late evening.. Topiramate-induced palinopsia may be underdiagnosed because physicians do not inquire about such visual symptoms.

Topics: Adult; Anticonvulsants; Female; Fructose; Humans; Illusions; Male; Middle Aged; Sensation Disorders; Topiramate; Visual Perception