topiramate and Panic-Disorder

We report a case of acute myopic recurrence in a 38-year-old patient in a state of panic with a condition corresponding to LASIK 4 months earlier. The patient had commenced topiramate treatment 1 week previously, which is an antiepileptic drug also approved for migraine treatment. The symptoms were due to a rare topiramate-induced side effect (SE) with ciliochoroidal effusion, anterior shift of the lens-iris diaphragm and induced myopia. Cessation of topiramate led to complete remission of this idiosyncratic reaction, however, the patient's anxiety was impressive. Ocular administration of Topiramat-SE should thus be clarified.

Topics: Adult; Anticonvulsants; Female; Fructose; Humans; Keratomileusis, Laser In Situ; Myopia; Panic Disorder; Recurrence; Topiramate; Treatment Outcome

Topics: Adolescent; Anti-Anxiety Agents; Borderline Personality Disorder; Emergency Medical Services; Female; Fructose; Humans; Lorazepam; Neuroprotective Agents; Panic Disorder; Topiramate

Topics: Adult; Anticonvulsants; Bipolar Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fructose; Humans; Lithium; Panic Disorder; Topiramate; Weight Gain

Topics: Adult; Anticonvulsants; Blushing; Face; Fructose; Humans; Hyperhidrosis; Male; Panic Disorder; Phobic Disorders; Topiramate; Treatment Outcome

Topics: Adult; Anticonvulsants; Female; Fructose; Humans; Panic Disorder; Topiramate