topiramate and Multiple-Sclerosis

Patients with POAG have lower corneal endothelial cell density than healthy controls of the same age. This may be attributed to mechanical damage from elevated IOP and toxicity of glaucoma medications.. Mycophenolic acid was detected in all cats. The dose 10 mg/kg given q12h for 1 week was tolerated (n = 3). The efficacy of MMF as an immunosuppressant and long-term safety in cats of this dosage regimen is unknown.. T

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Topics: Eye Movements; Humans; Multiple Sclerosis; Nystagmus, Pathologic; Topiramate

Dysaesthetic pain is a common neuropathic pain in patients with multiple sclerosis. Both tricyclic antidepressants (i.e., amitriptyline and duloxetine) and antiepileptic drugs (i.e., carbamazepine, gabapentin and pregabalin) represent first-line treatment of neuropathic pain. However, topiramate, an antiepileptic drug, also demonstrated clinical efficacy in these patients. In this report we describe the case of a 42-year-old woman with an 8-year history of multiple sclerosis who developed dysaesthetic pain in the lower limbs, and was successfully treated with topiramate at a final dose of 150 mg/day. About 8 months after beginning topiramate treatment, the patient had not shown any dysaesthetic pain, and no adverse events related to topiramate had been recorded.

Topics: Adult; Anticonvulsants; Female; Fructose; Humans; Lower Extremity; Multiple Sclerosis; Neuralgia; Topiramate; Treatment Outcome

Topics: Anticonvulsants; Female; Fructose; Humans; Middle Aged; Migraine Disorders; Multiple Sclerosis; Obsessive-Compulsive Disorder; Topiramate

Topics: Anticonvulsants; Female; Fructose; Humans; Middle Aged; Multiple Sclerosis; Receptors, AMPA; Topiramate; Trigeminal Neuralgia

Topics: Adult; Female; Fructose; Humans; Male; Multiple Sclerosis; Neuralgia; Neuroprotective Agents; Pain Measurement; Reflex; Topiramate; Treatment Outcome

Topics: Adult; Female; Fructose; Humans; Male; Multiple Sclerosis; Topiramate; Trigeminal Neuralgia