topiramate and Macular-Degeneration

topiramate has been researched along with Macular-Degeneration* in 2 studies

Other Studies

2 other study(ies) available for topiramate and Macular-Degeneration

ArticleYear
Presumed topiramate-induced maculopathy.
    Epilepsy & behavior : E&B, 2009, Volume: 14, Issue:3

    The case of a patient who developed decreased vision while taking topiramate (TPM) for symptomatic epilepsy is described. Ophthalmological examination revealed findings suggestive of maculopathy. TPM was discontinued; however, vision failed to improve significantly over 6 months of follow-up. We hypothesize that the patient's maculopathy was induced by TPM. TPM, like vigabatrin, may exert retinal toxicity causing persistent visual impairment.

    Topics: Adult; Anticonvulsants; Cerebral Angiography; Electroencephalography; Epilepsy, Generalized; Female; Fructose; Humans; Macular Degeneration; Magnetic Resonance Imaging; Topiramate; Vision Tests

2009
Electronegative electroretinogram associated with topiramate toxicity and vitelliform maculopathy.
    Documenta ophthalmologica. Advances in ophthalmology, 2008, Volume: 116, Issue:1

    Topiramate is known to cause ocular side effects such as refractive changes and angle closure. We describe a patient with an electronegative electroretinogram (ERG) which may have been related to topiramate use. Electronegative ERG's have been associated with other drugs in humans as well as topiramate use in rabbits. However, this would be the first suggestion of causality in humans.

    Topics: Adult; Anticonvulsants; Electroretinography; Female; Fructose; Humans; Macular Degeneration; Myoclonic Epilepsy, Juvenile; Retina; Topiramate

2008