topiramate and Intracranial-Aneurysm

topiramate has been researched along with Intracranial-Aneurysm* in 1 studies

Other Studies

1 other study(ies) available for topiramate and Intracranial-Aneurysm

ArticleYear
Adding topiramate to valproate therapy may cause reversible hepatic failure.
    Epileptic disorders : international epilepsy journal with videotape, 2003, Volume: 5, Issue:3

    The authors report a 51-year-old women with pharmacoresistant partial epilepsy who tolerated well valproate monotherapy and in combination with several other antiepileptic drugs, but developed symptoms and signs of reversible hepatic failure under a combination of valproate and topiramate. Symptoms resolved after discontinuation of VPA. This case provides further anecdotal evidence that topiramate may increase the risk of liver failure when given in combination with other potentially hepatotoxic antiepileptic drugs.

    Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Epilepsies, Partial; Female; Fructose; Humans; Intracranial Aneurysm; Liver Function Tests; Middle Aged; Postoperative Complications; Topiramate; Valproic Acid

2003