topiramate and Angelman-Syndrome

topiramate has been researched along with Angelman-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for topiramate and Angelman-Syndrome

Article	Year
Topiramate therapy of epilepsy associated with Angelman's syndrome. Neurology, 2000, Mar-14, Volume: 54, Issue:5 Angelman's syndrome, a genetic disorder involving a defect in the DNA coding for subunits of the gamma-aminobutyric acid (GABA) type A receptor, often is associated with intractable epilepsy. Topiramate is a novel anticonvulsant that enhances GABAergic neurotransmission. Five children with Angelman's syndrome and epilepsy were treated with topiramate for clinical indications. The drug was effective and well tolerated, possibly because of its GABAergic properties. Further studies are necessary to confirm and elucidate this observation. Topics: Angelman Syndrome; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Fructose; Humans; Male; Topiramate	2000

Article

Year

Topiramate therapy of epilepsy associated with Angelman's syndrome.

Neurology, 2000, Mar-14, Volume: 54, Issue:5

Angelman's syndrome, a genetic disorder involving a defect in the DNA coding for subunits of the gamma-aminobutyric acid (GABA) type A receptor, often is associated with intractable epilepsy. Topiramate is a novel anticonvulsant that enhances GABAergic neurotransmission. Five children with Angelman's syndrome and epilepsy were treated with topiramate for clinical indications. The drug was effective and well tolerated, possibly because of its GABAergic properties. Further studies are necessary to confirm and elucidate this observation.

Topics: Angelman Syndrome; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Fructose; Humans; Male; Topiramate

2000