toosendanin has been researched along with Acute Liver Injury, Drug-Induced in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S; Han, S; Huang, Z; Liang, Y; Luo, L; Shen, F | 1 |
| Fu, Y; Gong, S; Hu, X; Li, M; Li, N; Shen, X; Sun, B; Wu, H; Wu, JL; Zhang, Y; Zhuo, Y | 1 |
| Gao, S; Liang, Q; Liu, K; Liu, Q; She, G; Sun, M; Xia, Q; Zhang, H; Zhang, Y; Zhuang, K | 1 |
| Chen, W; Fan, X; Lu, X; Yu, L; Zheng, J | 1 |
| Huang, ZL; Ji, LL; Jin, Y; Li, L; Wang, CH; Wang, ZT; Yang, Y | 1 |
| Hu, DD; Li, F; Xiao, XR; Yang, R; Zhao, Q | 1 |
| Ji, L; Li, L; Sheng, Y; Wei, M; Yang, F; Yang, R | 1 |
| Fan, X; Gao, Y; Ji, C; Lian, X; Lu, X; Tong, W; Wu, Y | 1 |
8 other study(ies) available for toosendanin and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Toosendanin induced hepatotoxicity via triggering PERK-eIF2α-ATF4 mediated ferroptosis.
Topics: Activating Transcription Factor 4; Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Eukaryotic Initiation Factor-2; Ferroptosis; Male; Mice; Reactive Oxygen Species; Transcription Factor 4 | 2023 |
Hepatotoxic evaluation of toosendanin via biomarker quantification and pathway mapping of large-scale chemical proteomics.
Topics: Animals; Biomarkers; Blood Proteins; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Humans; Liver; Lysine; Male; Microsomes, Liver; Proteomics; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2021 |
Toosendanin triggered hepatotoxicity in zebrafish via inflammation, autophagy, and apoptosis pathways.
Topics: Animals; Apoptosis; Autophagy; Chemical and Drug Induced Liver Injury; Inflammation; Liver; Transcriptome; Triterpenes; Zebrafish; Zebrafish Proteins | 2021 |
Circulating exosomal microRNAs reveal the mechanism of Fructus Meliae Toosendan-induced liver injury in mice.
Topics: Animals; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Exosomes; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Mice; MicroRNAs; Up-Regulation | 2018 |
Quercetin attenuates toosendanin-induced hepatotoxicity through inducing the Nrf2/GCL/GSH antioxidant signaling pathway.
Topics: Animals; Cell Line; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Glutamate-Cysteine Ligase; Glutathione; Humans; Male; Mice, Inbred C57BL; NF-E2-Related Factor 2; Protective Agents; Quercetin; RNA, Messenger; Signal Transduction | 2019 |
Optimization of extraction and analytical protocol for mass spectrometry-based metabolomics analysis of hepatotoxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Drugs, Chinese Herbal; Liver; Male; Mass Spectrometry; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Toxicity Tests | 2018 |
Identification of serum microRNAs as potential toxicological biomarkers for toosendanin-induced liver injury in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Heterocyclic Compounds, 4 or More Rings; Liver; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; MicroRNAs; Monocrotaline; Random Allocation; Specific Pathogen-Free Organisms | 2019 |
Integrated analysis of microRNA and mRNA expression profiles highlights the complex and dynamic behavior of toosendanin-induced liver injury in mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; MicroRNAs; RNA, Messenger | 2016 |