tomoxiprole and Peptic-Ulcer

tomoxiprole has been researched along with Peptic-Ulcer* in 1 studies

Other Studies

1 other study(ies) available for tomoxiprole and Peptic-Ulcer

Article	Year
Highly selective antiinflammatory and analgesic activity of 3-(1-methylethyl)-2-(4-methoxyphenyl)-3H-naphth[1,2-d]imidazole, a new non-acidic molecule. Arzneimittel-Forschung, 1986, Volume: 36, Issue:1 3-(1-Methylethyl)-2-(4-methoxyphenyl)-3H-naphth[1,2-d] imidazole (MDL-035) has antiinflammatory activity in various antiinflammatory models such as carrageenin and nystatin oedemas, cotton pellet granuloma and adjuvant arthritis. The antiinflammatory potency of MDL-035 is greater than that of acetylsalicylic acid and phenylbutazone, but lower than that of indomethacin. MDL-035 has practically no gastroulcerogenic activity in rats, does not affect water or salt excretion, has no hormonal or antihormonal effects and has no other unwanted pharmacological effects. Its acute toxicity is very low. Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimental; Behavior, Animal; Blood Pressure; Cricetinae; Diarrhea; Dogs; Endocrine Glands; Female; Fertility; Imidazoles; Liver Glycogen; Luteinizing Hormone; Male; Mesocricetus; Mice; Ovulation; Peptic Ulcer; Rats; Rats, Inbred Strains; Water-Electrolyte Balance	1986

Article

Year

Highly selective antiinflammatory and analgesic activity of 3-(1-methylethyl)-2-(4-methoxyphenyl)-3H-naphth[1,2-d]imidazole, a new non-acidic molecule.

Arzneimittel-Forschung, 1986, Volume: 36, Issue:1

3-(1-Methylethyl)-2-(4-methoxyphenyl)-3H-naphth[1,2-d] imidazole (MDL-035) has antiinflammatory activity in various antiinflammatory models such as carrageenin and nystatin oedemas, cotton pellet granuloma and adjuvant arthritis. The antiinflammatory potency of MDL-035 is greater than that of acetylsalicylic acid and phenylbutazone, but lower than that of indomethacin. MDL-035 has practically no gastroulcerogenic activity in rats, does not affect water or salt excretion, has no hormonal or antihormonal effects and has no other unwanted pharmacological effects. Its acute toxicity is very low.

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimental; Behavior, Animal; Blood Pressure; Cricetinae; Diarrhea; Dogs; Endocrine Glands; Female; Fertility; Imidazoles; Liver Glycogen; Luteinizing Hormone; Male; Mesocricetus; Mice; Ovulation; Peptic Ulcer; Rats; Rats, Inbred Strains; Water-Electrolyte Balance

1986