tomaymycin has been researched along with Ovarian-Neoplasms* in 1 studies
1 other study(ies) available for tomaymycin and Ovarian-Neoplasms
Article | Year |
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Effect of C2-exo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c][1,4]benzodiazepines.
A series of novel C2-exo unsaturated pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) has been synthesised via a versatile pro-C2 ketone precursor. C2-exo-unsaturation enhances both DNA-binding reactivity and in vitro cytotoxic potency. Topics: Animals; Antibiotics, Antineoplastic; Benzodiazepines; Benzodiazepinones; DNA; Drug Screening Assays, Antitumor; Female; Humans; Molecular Structure; Ovarian Neoplasms; Pyrroles; Tumor Cells, Cultured | 2000 |