tolytoxin and Hemolysis

tolytoxin has been researched along with Hemolysis* in 1 studies

Other Studies

1 other study(ies) available for tolytoxin and Hemolysis

Article	Year
Biological effects of tolytoxin (6-hydroxy-7-O-methyl-scytophycin b), a potent bioactive metabolite from cyanobacteria. Archives of microbiology, 1992, Volume: 157, Issue:5 Tolytoxin, a macrocyclic lactone, is a potent antifungal antibiotic, exhibiting MICs in the range of 0.25 to 8 nanomolar. Tolytoxin also inhibits the growth of a variety of mammalian cells at similar doses, without specific inhibition of macromolecular synthesis. The effects in mammalian cells are primarily cytostatic, with cell death being time- and dose-dependent. Tolytoxin is highly toxic to mice, exhibiting an LD50 (ip) of 1.5 mg/kg. No antibacterial, antiviral, or hemolytic activities were observed. Topics: Animals; Antifungal Agents; Cell Division; Cell Survival; Cells, Cultured; Cyanobacteria; Female; Growth Inhibitors; Hemolysis; Male; Mice; Pyrans; Rats; Rats, Inbred Strains	1992

Article

Year

Biological effects of tolytoxin (6-hydroxy-7-O-methyl-scytophycin b), a potent bioactive metabolite from cyanobacteria.

Archives of microbiology, 1992, Volume: 157, Issue:5

Tolytoxin, a macrocyclic lactone, is a potent antifungal antibiotic, exhibiting MICs in the range of 0.25 to 8 nanomolar. Tolytoxin also inhibits the growth of a variety of mammalian cells at similar doses, without specific inhibition of macromolecular synthesis. The effects in mammalian cells are primarily cytostatic, with cell death being time- and dose-dependent. Tolytoxin is highly toxic to mice, exhibiting an LD50 (ip) of 1.5 mg/kg. No antibacterial, antiviral, or hemolytic activities were observed.

Topics: Animals; Antifungal Agents; Cell Division; Cell Survival; Cells, Cultured; Cyanobacteria; Female; Growth Inhibitors; Hemolysis; Male; Mice; Pyrans; Rats; Rats, Inbred Strains

1992