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toluene and Pregnancy

toluene has been researched along with Pregnancy in 128 studies

methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"We describe a patient in whom acute fatty liver of pregnancy developed after long-term toluene exposure."7.68Acute fatty liver of pregnancy after exposure to toluene. A case report. ( Jothy, S; Lewis, J; Paraf, F, 1993)
"Sex-, age- and pregnancy-induced changes in the metabolism of toluene and trichloroethylene in rat liver were investigated in relation to the regulation of cytochrome P450IIE1 and P450IIC11 content using monoclonal antibodies."7.68Sex-, age- and pregnancy-induced changes in the metabolism of toluene and trichloroethylene in rat liver in relation to the regulation of cytochrome P450IIE1 and P450IIC11 content. ( Elovaara, E; Gelboin, HV; Katakura, Y; Kishi, R; Nakajima, T; Park, SS; Vainio, H; Wang, RS, 1992)
"They had microcephaly, cerebral palsy, mental retardation, seizures, growth failure and minor craniofacial anomalies, variable growth deficiency including a small midface, narrow bifrontal diameter, low-set ears, thin upper lips and micrognathia."5.30[Two cases of toluene embryopathy with severe motor and intellectual disabilities syndrome]. ( Aida, N; Arai, H; Hara, M; Iwamoto, H; Miyake, S; Yamada, M; Yamashita, S, 1997)
"Five gravidas presented with severe renal tubular acidosis from paint sniffing."5.27Toluene abuse and renal tubular acidosis in pregnancy. ( Goodwin, TM, 1988)
" In both animal models and clinical case reports of toluene exposure, the primary physiological outcome measure of prenatal inhalant exposure is low birth weight (BW)."4.93Changes in developmental body weight as a function of toluene exposure: A meta-analysis of animal studies. ( Baltes, BB; Bowen, SE; Callan, SP; Cleary, JP; Kott, JM; McCarthy, MK, 2016)
" How these Internet resources can be utilized to obtain information on and evaluate the developmental risk associated with exposures during pregnancy will be illustrated using toluene."4.81Developmental toxicity: web resources for evaluating risk in humans. ( Faustman, EM; Polifka, JE, 2002)
"To determine if maternal toluene abuse produces any structural or developmental disabilities in the developing fetus, a cohort of toluene-exposed infants was ascertained and examined."4.79Toluene embryopathy: delineation of the phenotype and comparison with fetal alcohol syndrome. ( Hoyme, HE; Pearson, MA; Rimsza, ME; Seaver, LH, 1994)
"Volatile organic solvent abuse continues to be a worldwide health problem, including the neurobehavioral teratogenic sequelae of toluene abuse during pregnancy."3.85Prenatal toluene exposure impairs performance in the Morris Water Maze in adolescent rats. ( Bowen, SE; Callan, SP; Hannigan, JH, 2017)
"We estimated pregnancy and trimester-specific exposures to nitrogen dioxide and aromatic hydrocarbons [benzene, toluene, ethylbenzene, m/p-xylene, and o-xylene (BTEX)] by using temporally adjusted land-use regression (LUR) models."3.75Association between GIS-based exposure to urban air pollution during pregnancy and birth weight in the INMA Sabadell Cohort. ( Aguilera, I; Corbella, T; Foradada, CM; Garcia-Esteban, R; Guxens, M; Nieuwenhuijsen, MJ; Sunyer, J, 2009)
" These studies explored the effects of brief, repeated, prenatal toluene exposures in pregnant female rats on body weight, metabolic rate, body composition, and food intake in their offspring."3.74Effects of abuse pattern of gestational toluene exposure on metabolism, feeding and body composition. ( Bowen, SE; Coscina, DV; Fata, E; Jarosz, PA; Jen, KL, 2008)
"Little is known about the effect of inhalation of methanol and other solvents on the pregnancy and the growth of the fetus."3.72Intrauterine cerebral infarcts and bilateral frontal cortical leukomalacia following chronic maternal inhalation of carburetor cleaning fluid during pregnancy. ( Bharti, D, 2003)
"The present study was undertaken in order to investigate if toluene induced oxidative stress in brains from rats exposed prenatally to 1800 ppm toluene 6 hr/day at days 7-20 during the pregnancy."3.71Changes in markers of oxidative stress and membrane properties in synaptosomes from rats exposed prenatally to toluene. ( Edelfors, S; Hass, U; Hougaard, KS, 2002)
"Toluene inhalant abuse during pregnancy may result in growth-retarded microcephalic newborns who subsequently demonstrate developmental impairment."3.70Prenatal exposure to toluene results in abnormal neurogenesis and migration in rat somatosensory cortex. ( Gospe, SM; Zhou, SS, 2000)
"Pregnant Wistar rats were treated with different concentrations of toluene by inhalation (300, 600, 1000 and 1200 ppm) from day 9 to day 21 of pregnancy for 6 h a day in a whole-body inhalation chamber (controls inhaled fresh air only)."3.69Postnatal development and behaviour of Wistar rats after prenatal toluene exposure. ( Chahoud, I; Thiel, R, 1997)
"Developmental disability, intrauterine growth retardation, renal anomalies, and dysmorphic features have been described in offspring of women who abuse toluene during pregnancy."3.69The effects of high-dose toluene on embryonic development in the rat. ( Gospe, SM; Saeed, DB; Zeman, FJ; Zhou, SS, 1994)
"A rat model was developed to study toluene-abuse embryopathy, a clinical syndrome which occurs in offspring of women who abuse toluene during pregnancy."3.69Development of a rat model of toluene-abuse embryopathy. ( Gospe, SM; Saeed, DB; Zeman, FJ; Zhou, SS, 1996)
"We describe a patient in whom acute fatty liver of pregnancy developed after long-term toluene exposure."3.68Acute fatty liver of pregnancy after exposure to toluene. A case report. ( Jothy, S; Lewis, J; Paraf, F, 1993)
"Sex-, age- and pregnancy-induced changes in the metabolism of toluene and trichloroethylene in rat liver were investigated in relation to the regulation of cytochrome P450IIE1 and P450IIC11 content using monoclonal antibodies."3.68Sex-, age- and pregnancy-induced changes in the metabolism of toluene and trichloroethylene in rat liver in relation to the regulation of cytochrome P450IIE1 and P450IIC11 content. ( Elovaara, E; Gelboin, HV; Katakura, Y; Kishi, R; Nakajima, T; Park, SS; Vainio, H; Wang, RS, 1992)
"Toluene embryopathy is characterised by microcephaly, central nervous system dysfunction, attentional deficits and hyperactivity, developmental delay with greater language deficits, minor craniofacial and limb anomalies, and variable growth deficiency."3.67Toluene embryopathy: two new cases. ( Hersh, JH, 1989)
"Three children with microcephaly, central nervous system dysfunction, minor craniofacial and limb anomalies, and variable growth deficiency were born to women who inhaled large quantities of pure toluene throughout pregnancy."3.67Toluene embryopathy. ( Hersh, JH; Podruch, PE; Rogers, G; Weisskopf, B, 1985)
"On the 10th-13th days of pregnancy toluene (3600 mg/m3) by inhalation) and on 12th day acetylsalicylic acid (500 mg/kg of body weight per os) were administered to CFY rats and the common effect of these agents was studied."3.66[Experimental model for the study of the teratogenic interaction of chemical agents and drugs (toluene and acetylsalicylic acid)]. ( Hudák, A; Tátrai, E; Ungváry, G, 1979)
"Toluene is an organic solvent that is widely used by industry and is ubiquitous in our environment."2.46Reproductive toxicology and teratology of abused toluene. ( Bowen, SE; Hannigan, JH, 2010)
"Also, spontaneous abortion has generally not been observed as a major problem among highly exposed women who abuse toluene during pregnancy."2.41Review of the epidemiological evidence relating toluene to reproductive outcomes. ( Bukowski, JA, 2001)
"Chronic toluene abuse produces a renal tubular acidosis with maternal hypokalemia and profoundly lowered serum pH."2.40Teratogen update: toluene. ( Wilkins-Haug, L, 1997)
"Toluene is a widely used industrial solvent, and humans may also have high exposures to toluene from the deliberate inhalation ("sniffing") of paint reducer, paint thinner, or paint for their narcotic effects."2.38Reproductive and developmental toxicity of toluene: a review. ( Donald, JM; Hooper, K; Hopenhayn-Rich, C, 1991)
" Physiologically based pharmacokinetic models for adults (AD), neonates (NEO), toddlers (TODD), and pregnant women (PW) were used to simulate inhalation exposure to "low" (RfC-like) or "high" (AEGL-like) air concentrations of benzene (Bz) or dichloromethane (DCM), along with various levels of toluene alone or toluene with ethylbenzene and xylene."1.42Assessing human variability in kinetics for exposures to multiple environmental chemicals: a physiologically based pharmacokinetic modeling case study with dichloromethane, benzene, toluene, ethylbenzene, and m-xylene. ( Haddad, S; Valcke, M, 2015)
"Toluene is a commonly abused organic solvent."1.35Alterations in rat fetal morphology following abuse patterns of toluene exposure. ( Bowen, SE; Hannigan, JH; Irtenkauf, S; Stefanski, AL, 2009)
"Toluene has been shown to inhibit the nicotinic acetylcholine receptors."1.35Toluene exposure during the brain growth spurt reduced behavioral responses to nicotine in young adult rats: a potential role for nicotinic acetylcholine receptors in fetal solvent syndrome. ( Chan, MH; Chen, HH; Chien, TH; Tang, YC, 2008)
"Mean fetal weight was also reduced at 250ppm but not at 750ppm."1.34Developmental and reproductive toxicity evaluation of toluene vapor in the rat II. Developmental toxicity. ( Nicolich, MJ; Roberts, LG; Schreiner, CA, 2007)
" Thus, the possibility that 4-NT exerted endocrine disrupting effects seems to be very low under the conditions of this study, and when the substance was administered to rats over two generations, doses less than 160 mg/kg/day did not induce any marked adverse effects on the reproductive capacity in the parental animals, with the no observed effect level (NOEL) and the no observed adverse effect (NOAEL) on growth and development in the offspring concluded to be 40 mg/kg/day."1.33A two-generation reproductive toxicity study of 4-nitrotoluene in rats. ( Aso, S; Ehara, H; Hosyuyama, S; Minobe, Y; Miyata, K; Shiraishi, K; Umano, T, 2005)
"Substance abuse in pregnancy is associated with severe maternal and neonatal sequelae."1.31Solvent abuse in pregnancy: a perinatal perspective. ( Chudley, AE; Scheeres, JJ, 2002)
"Toluene was added to the perfusion medium and concentrations of toluene in the medium were determined by gas chromatographic analysis."1.31Toluene inhibits muscarinic receptor-mediated cytosolic Ca2+ responses in neural precursor cells. ( Barker, JL; Maric, D; O'Shaughnessy, TJ; Pancrazio, JJ; Shaffer, KM; Stenger, DA; Wu, M; Zhang, L, 2002)
"They had microcephaly, cerebral palsy, mental retardation, seizures, growth failure and minor craniofacial anomalies, variable growth deficiency including a small midface, narrow bifrontal diameter, low-set ears, thin upper lips and micrognathia."1.30[Two cases of toluene embryopathy with severe motor and intellectual disabilities syndrome]. ( Aida, N; Arai, H; Hara, M; Iwamoto, H; Miyake, S; Yamada, M; Yamashita, S, 1997)
" In conclusion, embryo-fetal toxic effects were apparent in female rats exposed to toluene before and during the early stage of pregnancy."1.29Reproductive and developmental toxicity studies of toluene. II. Effects of inhalation exposure on fertility in rats. ( Furuya, T; Hirose, A; Inoue, T; Kaneko, T; Kawashima, K; Kurokawa, Y; Matsumoto, K; Naito, K; Ogawa, Y; Ono, A; Saito, M; Sekita, K; Suzuki, S; Tanaka, S; Yasuhara, K, 1996)
"Toluene is a widely used solvent in industry which is the subject of abuse among the younger generation."1.29Reproductive and developmental toxicity studies of toluene. I. Teratogenicity study of inhalation exposure in pregnant rats. ( Furuya, T; Hirose, A; Kaneko, T; Matsumoto, K; Naito, K; Ogawa, Y; Ohno, K; Ono, A; Saito, M; Sekita, K, 1995)
"An accurate and sensitive yet simple protocol for the analysis of toluene in submilliliter quantities of whole blood using stable-isotope dilution GC-MS has been developed and evaluated for use in pharmacokinetic studies of toluene exposure."1.29Stable-isotope dilution GC-MS for determination of toluene in submilliliter volumes of whole blood. ( Dunlap, MR; Gospe, SM; Jones, AD, 1994)
"Rates of spontaneous abortions were determined using a reproductive questionnaire administered by personal interview to 55 married women with 105 pregnancies."1.28Risk of spontaneous abortion in workers exposed to toluene. ( Foo, SC; Ng, TP; Yoong, T, 1992)
"Toluene was found to potentiate the toxic effect of ASA and to increase both maternal and embryonic toxicity."1.27Combined embryotoxic action of toluene, a widely used industrial chemical, and acetylsalicylic acid (aspirin). ( Barcza, G; Lõrincz, M; Tátrai, E; Ungváry, G, 1983)
"Five gravidas presented with severe renal tubular acidosis from paint sniffing."1.27Toluene abuse and renal tubular acidosis in pregnancy. ( Goodwin, TM, 1988)

Research

Studies (128)

TimeframeStudies, this research(%)All Research%
pre-199050 (39.06)18.7374
1990's25 (19.53)18.2507
2000's33 (25.78)29.6817
2010's16 (12.50)24.3611
2020's4 (3.13)2.80

Authors

AuthorsStudies
Sirotkin, AV1
Tarko, A1
Kotwica, J1
Alrezaki, A1
Harrath, AH1
Nguépy Keubo, FR1
Mboua, PC1
Djifack Tadongfack, T1
Fokouong Tchoffo, E1
Tasson Tatang, C1
Ide Zeuna, J1
Noupoue, EM1
Tsoplifack, CB1
Folefack, GO1
Kettani, M1
Bandelier, P1
Huo, J1
Li, H4
Yu, D1
Arulsamy, N1
AlAbbad, S1
Sardot, T1
Lekashvili, O1
Decato, D1
Lelj, F1
Alexander Ross, JB1
Rosenberg, E1
Nazir, H1
Muthuswamy, N1
Louis, C1
Jose, S1
Prakash, J1
Buan, MEM1
Flox, C1
Chavan, S1
Shi, X1
Kauranen, P1
Kallio, T1
Maia, G1
Tammeveski, K1
Lymperopoulos, N1
Carcadea, E1
Veziroglu, E1
Iranzo, A1
M Kannan, A1
Arunamata, A1
Tacy, TA1
Kache, S1
Mainwaring, RD1
Ma, M1
Maeda, K1
Punn, R1
Noguchi, S1
Hahn, S3
Iwasa, Y3
Ling, J2
Voccio, JP2
Kim, Y3
Song, J3
Bascuñán, J2
Chu, Y1
Tomita, M1
Cazorla, M1
Herrera, E1
Palomeque, E1
Saud, N1
Hoplock, LB1
Lobchuk, MM1
Lemoine, J1
Li, X11
Henson, MA1
Unsihuay, D1
Qiu, J1
Swaroop, S1
Nagornov, KO1
Kozhinov, AN1
Tsybin, YO1
Kuang, S1
Laskin, J1
Zin, NNINM1
Mohamad, MN1
Roslan, K1
Abdul Wafi, S1
Abdul Moin, NI1
Alias, A1
Zakaria, Y1
Abu-Bakar, N1
Naveed, A1
Jilani, K1
Siddique, AB1
Akbar, M1
Riaz, M1
Mushtaq, Z1
Sikandar, M1
Ilyas, S1
Bibi, I1
Asghar, A1
Rasool, G1
Irfan, M1
Li, XY1
Zhao, S1
Fan, XH1
Chen, KP1
Hua, W1
Liu, ZM1
Xue, XD1
Zhou, B1
Zhang, S2
Xing, YL1
Chen, MA1
Sun, Y1
Neradilek, MB1
Wu, XT1
Zhang, D2
Huang, W1
Cui, Y1
Yang, QQ1
Li, HW1
Zhao, XQ1
Hossein Rashidi, B1
Tarafdari, A1
Ghazimirsaeed, ST1
Shahrokh Tehraninezhad, E1
Keikha, F1
Eslami, B1
Ghazimirsaeed, SM1
Jafarabadi, M1
Silvani, Y1
Lovita, AND1
Maharani, A1
Wiyasa, IWA1
Sujuti, H1
Ratnawati, R1
Raras, TYM1
Lemin, AS1
Rahman, MM1
Pangarah, CA1
Kiyu, A1
Zeng, C2
Du, H1
Lin, D1
Jalan, D1
Rubagumya, F1
Hopman, WM1
Vanderpuye, V1
Lopes, G1
Seruga, B1
Booth, CM1
Berry, S1
Hammad, N1
Sajo, EA1
Okunade, KS1
Olorunfemi, G1
Rabiu, KA1
Anorlu, RI1
Xu, C2
Xiang, Y1
Xu, X1
Zhou, L2
Dong, X1
Tang, S1
Gao, XC1
Wei, CH1
Zhang, RG1
Cai, Q1
He, Y1
Tong, F1
Dong, JH1
Wu, G1
Dong, XR1
Tang, X1
Tao, F1
Xiang, W1
Zhao, Y2
Jin, L1
Tao, H1
Lei, Y1
Gan, H1
Huang, Y1
Chen, Y4
Chen, L3
Shan, A1
Zhao, H2
Wu, M3
Ma, Q1
Wang, J4
Zhang, E1
Zhang, J3
Li, Y5
Xue, F1
Deng, L1
Liu, L2
Yan, Z2
Wang, Y3
Meng, J1
Chen, G2
Anastassiadou, M1
Bernasconi, G1
Brancato, A1
Carrasco Cabrera, L1
Greco, L1
Jarrah, S1
Kazocina, A1
Leuschner, R1
Magrans, JO1
Miron, I1
Nave, S1
Pedersen, R1
Reich, H1
Rojas, A1
Sacchi, A1
Santos, M1
Theobald, A1
Vagenende, B1
Verani, A1
Du, L1
Liu, X1
Ren, Y1
Li, J8
Li, P1
Jiao, Q1
Meng, P1
Wang, F2
Wang, YS1
Wang, C3
Zhou, X2
Wang, W1
Wang, S2
Hou, J1
Zhang, A1
Lv, B1
Gao, C1
Pang, D1
Lu, K1
Ahmad, NH1
Wang, L1
Zhu, J2
Zhang, L3
Zhuang, T1
Tu, J1
Zhao, Z1
Qu, Y1
Yao, H1
Wang, X5
Lee, DF1
Shen, J3
Wen, L1
Huang, G2
Xie, X1
Zhao, Q1
Hu, W1
Zhang, Y4
Wu, X1
Lu, J2
Li, M1
Li, W2
Wu, W1
Du, F1
Ji, H1
Yang, X2
Xu, Z1
Wan, L1
Wen, Q1
Cho, CH1
Zou, C1
Xiao, Z1
Liao, J1
Su, X1
Bi, Z1
Su, Q1
Huang, H1
Wei, Y2
Gao, Y2
Na, KJ1
Choi, H1
Oh, HR1
Kim, YH1
Lee, SB1
Jung, YJ1
Koh, J1
Park, S1
Lee, HJ1
Jeon, YK1
Chung, DH1
Paeng, JC1
Park, IK1
Kang, CH1
Cheon, GJ1
Kang, KW1
Lee, DS1
Kim, YT1
Pajuelo-Lozano, N1
Alcalá, S1
Sainz, B1
Perona, R1
Sanchez-Perez, I1
Logotheti, S1
Marquardt, S1
Gupta, SK1
Richter, C1
Edelhäuser, BAH1
Engelmann, D1
Brenmoehl, J1
Söhnchen, C1
Murr, N1
Alpers, M1
Singh, KP1
Wolkenhauer, O1
Heckl, D1
Spitschak, A1
Pützer, BM1
Liao, Y1
Cheng, J1
Kong, X1
Li, S1
Zhang, M4
Zhang, H1
Yang, T2
Dong, Y2
Xu, Y1
Yuan, Z1
Cao, J1
Zheng, Y1
Luo, Z1
Mei, Z1
Yao, Y1
Liu, Z2
Liang, C1
Yang, H1
Song, Y1
Yu, K1
Zhu, C1
Huang, Z1
Qian, J1
Ge, J1
Hu, J2
Wang, H2
Liu, Y4
Mi, Y1
Kong, H1
Xi, D1
Yan, W1
Luo, X1
Ning, Q1
Chang, X2
Zhang, T2
Wang, Q2
Rathore, MG1
Reddy, K1
Chen, H2
Shin, SH1
Ma, WY1
Bode, AM1
Dong, Z1
Mu, W1
Liu, C3
Gao, F1
Qi, Y1
Lu, H1
Zhang, X4
Cai, X1
Ji, RY1
Hou, Y3
Tian, J2
Shi, Y1
Ying, S1
Tan, M1
Feng, G1
Kuang, Y1
Chen, D1
Wu, D3
Zhu, ZQ1
Tang, HX1
Shi, ZE1
Kang, J1
Liu, Q1
Qi, J2
Mu, J1
Cong, Z1
Chen, S2
Fu, D1
Li, Z2
Celestrin, CP1
Rocha, GZ1
Stein, AM1
Guadagnini, D1
Tadelle, RM1
Saad, MJA1
Oliveira, AG1
Bianconi, V1
Bronzo, P1
Banach, M1
Sahebkar, A1
Mannarino, MR1
Pirro, M1
Patsourakos, NG1
Kouvari, M1
Kotidis, A1
Kalantzi, KI1
Tsoumani, ME1
Anastasiadis, F1
Andronikos, P1
Aslanidou, T1
Efraimidis, P1
Georgiopoulos, A1
Gerakiou, K1
Grigoriadou-Skouta, E1
Grigoropoulos, P1
Hatzopoulos, D1
Kartalis, A1
Lyras, A1
Markatos, G1
Mikrogeorgiou, A1
Myroforou, I1
Orkopoulos, A1
Pavlidis, P1
Petras, C1
Riga, M1
Skouloudi, M1
Smyrnioudis, N1
Thomaidis, K1
Tsikouri, GE1
Tsikouris, EI1
Zisimos, K1
Vavoulis, P1
Vitali, MG1
Vitsas, G1
Vogiatzidis, C1
Chantanis, S1
Fousas, S1
Panagiotakos, DB1
Tselepis, AD1
Jungen, C1
Alken, FA1
Eickholt, C1
Scherschel, K1
Kuklik, P1
Klatt, N1
Schwarzl, J1
Moser, J1
Jularic, M1
Akbulak, RO1
Schaeffer, B1
Willems, S1
Meyer, C1
Nowak, JK1
Szczepanik, M1
Trypuć, M1
Pogorzelski, A1
Bobkowski, W1
Grytczuk, M1
Minarowska, A1
Wójciak, R1
Walkowiak, J1
Lu, Y1
Xi, J1
Li, C1
Chen, W2
Hu, X1
Zhang, F1
Wei, H1
Wang, Z1
Gurzu, S1
Jung, I1
Sugimura, H2
Stefan-van Staden, RI1
Yamada, H1
Natsume, H1
Iwashita, Y1
Szodorai, R1
Szederjesi, J1
Yari, D1
Ehsanbakhsh, Z1
Validad, MH1
Langroudi, FH1
Esfandiari, H1
Prager, A1
Hassanpour, K1
Kurup, SP1
Mets-Halgrimson, R1
Yoon, H1
Zeid, JL1
Mets, MB1
Rahmani, B1
Araujo-Castillo, RV1
Culquichicón, C1
Solis Condor, R1
Efendi, F1
Sebayang, SK1
Astutik, E1
Hadisuyatmana, S1
Has, EMM1
Kuswanto, H1
Foroutan, T1
Ahmadi, F1
Moayer, F1
Khalvati, S1
Zhang, Q2
Lyu, Y1
Huang, J1
Yu, N1
Wen, Z1
Hou, H1
Zhao, T1
Gupta, A1
Khosla, N1
Govindasamy, V1
Saini, A1
Annapurna, K1
Dhakate, SR1
Akkaya, Ö1
Chandgude, AL1
Dömling, A1
Harnett, J1
Oakes, K1
Carè, J1
Leach, M1
Brown, D1
Cramer, H1
Pinder, TA1
Steel, A1
Anheyer, D1
Cantu, J1
Valle, J1
Flores, K1
Gonzalez, D1
Valdes, C1
Lopez, J1
Padilla, V1
Alcoutlabi, M1
Parsons, J1
Núñez, K1
Hamed, M1
Fort, D1
Bruce, D1
Thevenot, P1
Cohen, A1
Weber, P1
Menezes, AMB1
Gonçalves, H1
Perez-Padilla, R1
Jarvis, D1
de Oliveira, PD1
Wehrmeister, FC1
Mir, S1
Wong, J1
Ryan, CM1
Bellingham, G1
Singh, M2
Waseem, R1
Eckert, DJ1
Chung, F1
Hegde, H1
Shimpi, N1
Panny, A1
Glurich, I1
Christie, P1
Acharya, A1
English, KL1
Downs, M1
Goetchius, E1
Buxton, R1
Ryder, JW1
Ploutz-Snyder, R1
Guilliams, M1
Scott, JM1
Ploutz-Snyder, LL1
Martens, C1
Goplen, FK1
Aasen, T1
Gjestad, R1
Nordfalk, KF1
Nordahl, SHG1
Inoue, T2
Soshi, S1
Kubota, M1
Marumo, K1
Mortensen, NP1
Caffaro, MM1
Patel, PR2
Uddin, MJ1
Aravamudhan, S1
Sumner, SJ1
Fennell, TR1
Gal, RL1
Cohen, NJ1
Kruger, D1
Beck, RW1
Bergenstal, RM1
Calhoun, P1
Cushman, T1
Haban, A1
Hood, K1
Johnson, ML1
McArthur, T1
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Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Prenatal DHA Supplements on Infant Development[NCT00646360]1,094 participants (Actual)Interventional2005-02-28Completed
Imaging Innovations for Placental Assessment in Response to Environmental Pollution[NCT02786420]199 participants (Actual)Observational2015-10-02Completed
Impact of Fish Oil or Probiotic Intake on Maternal Obesity and Molecular Biomarkers in the Placenta[NCT03215784]80 participants (Anticipated)Interventional2015-03-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

16 reviews available for toluene and Pregnancy

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Changes in developmental body weight as a function of toluene exposure: A meta-analysis of animal studies.
    Human & experimental toxicology, 2016, Volume: 35, Issue:4

    Topics: Animals; Birth Weight; Female; Inhalation Exposure; Pregnancy; Research Design; Solvents; Toluene

2016
Reproductive toxicology and teratology of abused toluene.
    Systems biology in reproductive medicine, 2010, Volume: 56, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Developmental Disabilities; Female; Humans; Infant, Low

2010
Substance use and misuse in pregnancy: peripartum anesthetic management of a parturient with recent methanol toluene and isopropanol intake.
    Acta anaesthesiologica Belgica, 2004, Volume: 55, Issue:1

    Topics: 2-Propanol; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Female; Fetal Dist

2004
Developmental toxicity of prenatal exposure to toluene.
    The AAPS journal, 2006, Volume: 8, Issue:2

    Topics: Animals; Environmental Exposure; Female; Humans; Incidence; Models, Animal; Pregnancy; Prenatal Expo

2006
Behavioral toxicology and environmental health science. Opportunity and challenge for psychology.
    The American psychologist, 1983, Volume: 38, Issue:11

    Topics: Air Pollutants; Animals; Behavior; Carbon Disulfide; Child, Preschool; Developmental Disabilities; E

1983
Toxicology of saccharin.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:5

    Topics: Animals; Biological Assay; Drug Contamination; Female; Fetus; Humans; Legislation, Drug; Male; Pregn

1984
Toluene embryopathy: delineation of the phenotype and comparison with fetal alcohol syndrome.
    Pediatrics, 1994, Volume: 93, Issue:2

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Developmental Disabilities; Embryo, Mammalian; Ethan

1994
Teratogen update: toluene.
    Teratology, 1997, Volume: 55, Issue:2

    Topics: Abnormalities, Drug-Induced; Acidosis, Renal Tubular; Administration, Inhalation; Administration, Or

1997
Review of the epidemiological evidence relating toluene to reproductive outcomes.
    Regulatory toxicology and pharmacology : RTP, 2001, Volume: 33, Issue:2

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Bias; Confounding Factors, Epidemiologic; Epidem

2001
Developmental toxicity: web resources for evaluating risk in humans.
    Toxicology, 2002, Apr-25, Volume: 173, Issue:1-2

    Topics: Abnormalities, Drug-Induced; Databases as Topic; Embryonic and Fetal Development; Female; Humans; In

2002
Toluene. A toxicologic review.
    Scandinavian journal of work, environment & health, 1979, Volume: 5, Issue:2

    Topics: Brain; Chemical Phenomena; Chemistry; Chromosomes; Digestive System; Endocrine Glands; Environmental

1979
Reproductive and developmental toxicity of toluene: a review.
    Environmental health perspectives, 1991, Volume: 94

    Topics: Abnormalities, Drug-Induced; Animals; Embryonic and Fetal Development; Female; Growth; Humans; Infan

1991
Maternal exposure to environmental chemicals.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Arsenic; Environmental Exposure; Female; Humans; Hydrocarbons, Chlorinated; Hydrogen Sulfide; Kineti

1986
An overview of environmental and toxicological aspects of aromatic hydrocarbons. II. Toluene.
    The Science of the total environment, 1985, Volume: 42, Issue:3

    Topics: Animals; Chromosome Aberrations; Environmental Exposure; Environmental Pollutants; Female; Fetus; Hu

1985
Prolongation of life: role of free radical reactions in aging.
    Journal of the American Geriatrics Society, 1969, Volume: 17, Issue:8

    Topics: Aged; Aging; Amyloidosis; Animals; Arteriosclerosis; Chemistry, Organic; Chickens; Diet; Dietary Fat

1969

Trials

1 trial available for toluene and Pregnancy

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021

Other Studies

112 other studies available for toluene and Pregnancy

ArticleYear
Interrelationships between metabolic hormones, leptin and ghrelin, and oil-related contaminants in control of oxytocin and prostaglandin F release by feline ovaries.
    Reproductive biology, 2020, Volume: 20, Issue:2

    Topics: Animals; Cats; Environmental Pollutants; Female; Gene Expression Regulation; Ghrelin; Humans; Leptin

2020
An in vitro model to assess the peripheral vestibulotoxicity of aromatic solvents.
    Neurotoxicology, 2021, Volume: 84

    Topics: Animals; Animals, Newborn; Cells, Cultured; Cochlea; Dose-Response Relationship, Drug; Female; Hydro

2021
Ambient BTEX exposure and mid-pregnancy inflammatory biomarkers in pregnant African American women.
    Journal of reproductive immunology, 2021, Volume: 145

    Topics: Adolescent; Adult; Air Pollutants; Benzene; Benzene Derivatives; Biomarkers; Black or African Americ

2021
Prenatal exposure to environmental pollutants and child development trajectories through 7 years.
    International journal of hygiene and environmental health, 2018, Volume: 221, Issue:4

    Topics: Benzene; Child; Child Development; Child, Preschool; Cognition; Environmental Pollutants; Female; Hu

2018
Pifithrin-Alpha Reduces Methamphetamine Neurotoxicity in Cultured Dopaminergic Neurons.
    Neurotoxicity research, 2019, Volume: 36, Issue:2

    Topics: Animals; Benzothiazoles; Cell Line, Tumor; Cells, Cultured; Central Nervous System Stimulants; Dopam

2019
Evaluating the effects of maternal exposure to benzene, toluene, ethyl benzene, and xylene on oral clefts among offspring in Texas: 1999-2008.
    Birth defects research. Part A, Clinical and molecular teratology, 2013, Volume: 97, Issue:8

    Topics: Adult; Air Pollutants; Benzene; Benzene Derivatives; Brain; Case-Control Studies; Cleft Lip; Cleft P

2013
[Neurotoxic effect of toluene on background of prenatal hypoxic brain damage to white rats].
    Meditsina truda i promyshlennaia ekologiia, 2014, Issue:4

    Topics: Animals; Behavior, Animal; Brain; Cognition Disorders; Disease Models, Animal; Electroencephalograph

2014
Intrauterine ischemic reperfusion switches the fetal transcriptional pattern from HIF-1α- to P53-dependent regulation in the murine brain.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Animals; Benzothiazoles; Brain Injuries; Female; Fetus; Gene Expression Regulation; Hypoxia-Inducibl

2014
p53 inhibition provides a pivotal protective effect against ischemia-reperfusion injury in vitro via mTOR signaling.
    Brain research, 2015, Apr-24, Volume: 1605

    Topics: Animals; Benzothiazoles; Cells, Cultured; Female; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective

2015
Assessing human variability in kinetics for exposures to multiple environmental chemicals: a physiologically based pharmacokinetic modeling case study with dichloromethane, benzene, toluene, ethylbenzene, and m-xylene.
    Journal of toxicology and environmental health. Part A, 2015, Volume: 78, Issue:7

    Topics: Adolescent; Adult; Aged; Benzene; Benzene Derivatives; Child, Preschool; Computer Simulation; Female

2015
Prenatal toluene exposure impairs performance in the Morris Water Maze in adolescent rats.
    Neuroscience, 2017, 02-07, Volume: 342

    Topics: Animals; Disease Models, Animal; Female; Male; Maze Learning; Pregnancy; Prenatal Exposure Delayed E

2017
Toluene disruption of the functions of L1 cell adhesion molecule at concentrations associated with occupational exposures.
    Pediatric research, 2016, Volume: 80, Issue:1

    Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Female; Laminin; Maternal Exposure; Membrane Mi

2016
Regulation of MMP-9 by p53 in first trimester cytotrophoblastic cells.
    Human reproduction (Oxford, England), 2008, Volume: 23, Issue:10

    Topics: Benzothiazoles; Blotting, Western; Etoposide; Female; Gene Expression Regulation, Developmental; Hum

2008
Bmp2 is required for cephalic neural tube closure in the mouse.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2009, Volume: 238, Issue:1

    Topics: Animals; Apoptosis; Benzothiazoles; Body Patterning; Bone Morphogenetic Protein 2; Chimera; Female;

2009
The association between exposure to the oil and gas industry and beef calf mortality in Western Canada.
    Archives of environmental & occupational health, 2008,Winter, Volume: 63, Issue:4

    Topics: Animals; British Columbia; Cattle; Confidence Intervals; Environmental Exposure; Environmental Monit

2008
Risk of nonpregnancy, risk of disposal for pregnant cows, and duration of the calving interval in cow-calf herds exposed to the oil and gas industry in Western Canada.
    Archives of environmental & occupational health, 2008,Winter, Volume: 63, Issue:4

    Topics: Alberta; Animals; Benzene; British Columbia; Cattle; Confidence Intervals; Environmental Exposure; E

2008
Effects of maternal toluene exposure on testosterone levels in fetal rats.
    Toxicology letters, 2009, Mar-10, Volume: 185, Issue:2

    Topics: Air Pollutants; Animals; Enzyme-Linked Immunosorbent Assay; Female; Fetal Blood; Inhalation Exposure

2009
[BTEX exposure and its health effects in pregnant women following the Hebei Spirit oil spill].
    Journal of preventive medicine and public health = Yebang Uihakhoe chi, 2009, Volume: 42, Issue:2

    Topics: Adult; Benzene; Benzene Derivatives; Disasters; Environmental Exposure; Environmental Pollutants; Ey

2009
Alterations in rat fetal morphology following abuse patterns of toluene exposure.
    Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 27, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Crown-Rump Length; Dose-Response Relationship,

2009
Children's immunology, what can we learn from animal studies (2): Modulation of systemic Th1/Th2 immune response in infant mice after prenatal exposure to low-level toluene and toll-like receptor (TLR) 2 ligand.
    The Journal of toxicological sciences, 2009, Volume: 34 Suppl 2

    Topics: Animals; Cytokines; Environmental Pollutants; Female; Immunoglobulins; Inhalation Exposure; Ligands;

2009
Suppression of Th1- and Th2-type immune responses in infant mouse spleen after prenatal and postnatal exposure to low-level toluene and peptidoglycan.
    Inhalation toxicology, 2009, Volume: 21, Issue:9

    Topics: Air Pollutants; Animals; Cytokines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fem

2009
Association between GIS-based exposure to urban air pollution during pregnancy and birth weight in the INMA Sabadell Cohort.
    Environmental health perspectives, 2009, Volume: 117, Issue:8

    Topics: Adolescent; Adult; Air Pollutants; Benzene; Benzene Derivatives; Birth Weight; Environmental Exposur

2009
Does early life toluene exposure alter the expression of NMDA receptor subunits and signal transduction pathway in infant mouse hippocampus?
    Neurotoxicology, 2010, Volume: 31, Issue:6

    Topics: Age Factors; Animals; Animals, Newborn; Female; Gene Expression Regulation, Developmental; Hippocamp

2010
Hypoxia downregulates p53 but induces apoptosis and enhances expression of BAD in cultures of human syncytiotrophoblasts.
    American journal of physiology. Cell physiology, 2010, Volume: 299, Issue:5

    Topics: Animals; Apoptosis; bcl-Associated Death Protein; Benzothiazoles; Cells, Cultured; Down-Regulation;

2010
Differential mRNA expression of neuroimmune markers in the hippocampus of infant mice following toluene exposure during brain developmental period.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:2

    Topics: Animals; Animals, Newborn; Cytokines; Female; Gene Expression Regulation, Developmental; Gestational

2012
Developmental stage-specific changes in immunological biomarkers in male C3H/HeN mice after early life toluene exposure.
    Toxicology letters, 2012, Jan-25, Volume: 208, Issue:2

    Topics: Animals; Animals, Newborn; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Fo

2012
Structural neuroplasticity induced by melatonin in entorhinal neurons of rats exposed to toluene inhalation.
    Acta neurobiologiae experimentalis, 2011, Volume: 71, Issue:4

    Topics: Administration, Inhalation; Animals; Dendrites; Entorhinal Cortex; Female; Melatonin; Neuronal Plast

2011
Toluene inhibits muscarinic receptor-mediated cytosolic Ca2+ responses in neural precursor cells.
    Neurotoxicology, 2002, Volume: 23, Issue:1

    Topics: Animals; Calcium; Cell Differentiation; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug;

2002
Solvent abuse in pregnancy: a perinatal perspective.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2002, Volume: 24, Issue:1

    Topics: Acidosis, Renal Tubular; Adolescent; Adult; Brain Injuries; Female; Fetal Alcohol Spectrum Disorders

2002
Developmental neurotoxicity of toluene in rats as measured by L-ornithine decarboxylase in cerebellum.
    Pharmacology & toxicology, 2003, Volume: 92, Issue:1

    Topics: Animals; Cerebellum; Female; Immunohistochemistry; Male; Nerve Tissue Proteins; Nervous System; Neur

2003
Toluene depresses plasma corticosterone in pregnant rats.
    Pharmacology & toxicology, 2003, Volume: 92, Issue:3

    Topics: Animals; Animals, Newborn; Birth Weight; Corticosterone; Embryonic and Fetal Development; Female; Ma

2003
[Studies on practical application of certain colorimetric reactions of chorionic gonadotropin. I. Reaction to orcin].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:12

    Topics: Body Fluids; Chorion; Chorionic Gonadotropin; Female; Gonadotropins; Pregnancy; Toluene; Urine

1953
HYPOFIBRINOGENEMIA AND INTRAUTERINE FETAL DEATH.
    American journal of obstetrics and gynecology, 1964, Aug-01, Volume: 89

    Topics: ABO Blood-Group System; Afibrinogenemia; Blood Coagulation Tests; Blood Group Incompatibility; Blood

1964
Intrauterine cerebral infarcts and bilateral frontal cortical leukomalacia following chronic maternal inhalation of carburetor cleaning fluid during pregnancy.
    Journal of perinatology : official journal of the California Perinatal Association, 2003, Volume: 23, Issue:8

    Topics: Acetone; Acidosis; Cerebral Infarction; Drug Combinations; Female; Fetal Diseases; Humans; Infant, N

2003
Monitoring of the benzene and toluene contents in human milk.
    Environment international, 2004, Volume: 30, Issue:3

    Topics: Adult; Benzene; Environmental Pollutants; Female; Gas Chromatography-Mass Spectrometry; Humans; Milk

2004
Effects of combined prenatal stress and toluene exposure on apoptotic neurodegeneration in cerebellum and hippocampus of rats.
    Basic & clinical pharmacology & toxicology, 2004, Volume: 94, Issue:4

    Topics: Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; Caspases; Cerebellum; Embryonic and Fetal De

2004
Toluene exposure during the brain growth spurt reduces behavioral responses to noncompetitive N-methyl-D-aspartate receptor antagonists in adult rats.
    Psychopharmacology, 2005, Volume: 182, Issue:4

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal;

2005
A two-generation reproductive toxicity study of 4-nitrotoluene in rats.
    The Journal of toxicological sciences, 2005, Volume: 30 Spec No.

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Male;

2005
Increased hippocampal mRNA expression of neuronal synaptic plasticity related genes in mice chronically exposed to toluene at a low-level human occupational-exposure.
    Neurotoxicology, 2007, Volume: 28, Issue:1

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP Response Element-Binding Protein;

2007
Developmental and reproductive toxicity evaluation of toluene vapor in the rat II. Developmental toxicity.
    Reproductive toxicology (Elmsford, N.Y.), 2007, Volume: 23, Issue:4

    Topics: Abnormalities, Drug-Induced; Air Pollutants; Animals; Body Weight; Bone and Bones; Dose-Response Rel

2007
Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kappaB transcriptional activity.
    Cell death and differentiation, 2007, Volume: 14, Issue:8

    Topics: Animals; Apoptosis; Benzothiazoles; Brain Injuries; Disease Models, Animal; Female; Humans; Male; Mi

2007
Athymic nude mice are insensitive to low-level toluene-induced up-regulation of memory-related gene expressions in the hippocampus.
    Neurotoxicology, 2007, Volume: 28, Issue:5

    Topics: Animals; Body Weight; CD3 Complex; Cell Count; DNA, Complementary; Female; Gene Expression; Hippocam

2007
Toluene exposure during the brain growth spurt reduced behavioral responses to nicotine in young adult rats: a potential role for nicotinic acetylcholine receptors in fetal solvent syndrome.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 101, Issue:2

    Topics: Aging; Animals; Behavior, Animal; Blotting, Western; Body Temperature; Brain; Disease Models, Animal

2008
Effects of abuse pattern of gestational toluene exposure on metabolism, feeding and body composition.
    Physiology & behavior, 2008, Mar-18, Volume: 93, Issue:4-5

    Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Body Composition; Body Weight; Do

2008
Effect of benzene and its methyl-derivatives (toluene, para-xylene) on postganglionic noradrenergic nerves.
    Zeitschrift fur mikroskopisch-anatomische Forschung, 1984, Volume: 98, Issue:5

    Topics: Adrenergic Fibers; Animals; Autonomic Fibers, Postganglionic; Benzene; Female; Fluorescent Antibody

1984
Recommended health-based limits in occupational exposure to selected organic solvents.
    World Health Organization technical report series, 1981, Volume: 664

    Topics: Animals; Carbon Disulfide; Environmental Exposure; Female; Humans; Male; Maximum Allowable Concentra

1981
Combined embryotoxic action of toluene, a widely used industrial chemical, and acetylsalicylic acid (aspirin).
    Teratology, 1983, Volume: 27, Issue:2

    Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Animals; Aspirin; Drug Interactions; Embryo, Mammalian;

1983
Effects of maternal exposure to toluene during pregnancy on mouse embryos and fetuses.
    The Tokai journal of experimental and clinical medicine, 1982, Volume: 7, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Embryo Implantation; Embryo, Mammalian; Female

1982
Syndromes of toluene sniffing in adults.
    Annals of internal medicine, 1981, Volume: 94, Issue:6

    Topics: Adolescent; Adult; Female; Gastrointestinal Diseases; Humans; Kidney Diseases; Kidney Tubules; Male;

1981
Inhalant abuse, pregnancy, and neglected children.
    The American journal of psychiatry, 1981, Volume: 138, Issue:8

    Topics: Child; Child Abuse; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Pregnancy; Substance-

1981
Behavioral effects of low-level perinatal exposure to toluene in mice.
    Neurobehavioral toxicology and teratology, 1981,Winter, Volume: 3, Issue:4

    Topics: Animals; Behavior, Animal; Female; Fetus; Male; Mice; Mice, Inbred Strains; Pregnancy; Sex Factors;

1981
Embryotoxic effects of simultaneously applied exposure of benzene and toluene.
    Folia morphologica, 1980, Volume: 28, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Benzene; Body Weight; Female; Fetal Growth Retardation; Fetus;

1980
Reproductive and developmental toxicity studies of toluene. I. Teratogenicity study of inhalation exposure in pregnant rats.
    The Journal of toxicological sciences, 1995, Volume: 20, Issue:2

    Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Animals; Animals, Newborn; Embryonic and Fe

1995
Toluene embryopathy: clinical delineation and developmental follow-up.
    Pediatrics, 1994, Volume: 93, Issue:2

    Topics: Abnormalities, Drug-Induced; Developmental Disabilities; Embryo, Mammalian; Face; Female; Follow-Up

1994
The effects of high-dose toluene on embryonic development in the rat.
    Pediatric research, 1994, Volume: 36, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Femal

1994
Stable-isotope dilution GC-MS for determination of toluene in submilliliter volumes of whole blood.
    Journal of analytical toxicology, 1994, Volume: 18, Issue:5

    Topics: Animals; Female; Gas Chromatography-Mass Spectrometry; Indicator Dilution Techniques; Isotopes; Male

1994
Laboratory work and pregnancy outcome.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1994, Volume: 36, Issue:3

    Topics: Abortion, Spontaneous; Adult; Birth Weight; Case-Control Studies; Congenital Abnormalities; Female;

1994
Immunochemical assessment of the influence of nutritional, physiological and environmental factors on the metabolism of toluene.
    International archives of occupational and environmental health, 1993, Volume: 65, Issue:1 Suppl

    Topics: Animals; Cytochrome P-450 Enzyme System; Diet; Environmental Exposure; Female; Isoenzymes; Male; Mic

1993
Acute fatty liver of pregnancy after exposure to toluene. A case report.
    Journal of clinical gastroenterology, 1993, Volume: 17, Issue:2

    Topics: Acute Disease; Adult; Fatty Liver; Female; Humans; Pregnancy; Pregnancy Complications; Pregnancy Out

1993
Development of a rat model of toluene-abuse embryopathy.
    Pediatric research, 1996, Volume: 40, Issue:1

    Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Brain; Disease Models, Animal; Eating; F

1996
In vitro assessment of the effect of methanol and the metabolite, formic acid, on embryonic development of the rat.
    Teratology, 1995, Volume: 52, Issue:4

    Topics: Animals; Drug Combinations; Embryonic and Fetal Development; Female; Formates; Humans; Hydrogen-Ion

1995
Reproductive and developmental toxicity studies of toluene. II. Effects of inhalation exposure on fertility in rats.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1996, Volume: 15, Issue:1

    Topics: Administration, Inhalation; Animals; Embryonic and Fetal Development; Female; Fertility; Fetal Death

1996
Postnatal development and behaviour of Wistar rats after prenatal toluene exposure.
    Archives of toxicology, 1997, Volume: 71, Issue:4

    Topics: Animals; Animals, Newborn; Discrimination Learning; Female; Fertility; Litter Size; Locomotion; Preg

1997
[Two cases of toluene embryopathy with severe motor and intellectual disabilities syndrome].
    No to hattatsu = Brain and development, 1997, Volume: 29, Issue:5

    Topics: Abnormalities, Drug-Induced; Cerebral Palsy; Child; Craniofacial Abnormalities; Female; Humans; Infa

1997
Exposure to toluene in the printing industry is associated with subfecundity in women but not in men.
    Occupational and environmental medicine, 1999, Volume: 56, Issue:7

    Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Humans; Infertility, Female; Male; Occupational

1999
Prenatal exposure to toluene results in abnormal neurogenesis and migration in rat somatosensory cortex.
    Pediatric research, 2000, Volume: 47, Issue:3

    Topics: Animals; Female; Pregnancy; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Teratogens; Toluene

2000
Developmental toxicity of toluene in male rats: effects on semen quality, testis morphology, and apoptotic neurodegeneration.
    Archives of toxicology, 2001, Volume: 75, Issue:2

    Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Animals; Animals, Newborn; Apoptosis; Body

2001
Changes in markers of oxidative stress and membrane properties in synaptosomes from rats exposed prenatally to toluene.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:1

    Topics: Animals; Body Weight; Cell Membrane; Female; Maternal-Fetal Exchange; Oxidative Stress; Pregnancy; P

2002
Developmental neurotoxicity: do similar phenotypes indicate a common mode of action? A comparison of fetal alcohol syndrome, toluene embryopathy and maternal phenylketonuria.
    Toxicology letters, 2002, Feb-28, Volume: 127, Issue:1-3

    Topics: Alcohol-Induced Disorders, Nervous System; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorder

2002
Fetal solvents syndrome.
    Lancet (London, England), 1979, Jun-23, Volume: 1, Issue:8130

    Topics: Abnormalities, Multiple; Female; Fetal Alcohol Spectrum Disorders; Fetus; Humans; Infant, Newborn; M

1979
[Experimental model for the study of the teratogenic interaction of chemical agents and drugs (toluene and acetylsalicylic acid)].
    Morphologiai es igazsagugyi orvosi szemle, 1979, Volume: 19, Issue:4

    Topics: Animals; Aspirin; Drug Interactions; Female; Models, Biological; Pregnancy; Rats; Teratogens; Toluen

1979
[Working conditions and the state of health of women working with organosilicon varnishes containing toluene].
    Gigiena truda i professional'nye zabolevaniia, 1977, Issue:12

    Topics: Air Pollutants, Occupational; Electronics; Environmental Exposure; Female; Health; Humans; Occupatio

1977
Teratogenicity of 2,5-diaminotoluene, a hair-dye constituent, in mice.
    Food and cosmetics toxicology, 1977, Volume: 15, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Coloring Agents; Cosmetics; Female; Fetal Deat

1977
Uterine prostaglandin E secretion and uterine blood flow in the pregnant rabbit.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:1

    Topics: Animals; Blood Pressure; Cardiac Output; Cerium Isotopes; Chromatography; Depression, Chemical; Fema

1975
Studies on the prenatal toxicity of toluene in rabbits following inhalation exposure and proposal of a pregnancy guidance value.
    Archives of toxicology, 1992, Volume: 66, Issue:6

    Topics: Administration, Inhalation; Animals; Bone and Bones; Female; Fetus; Pregnancy; Rabbits; Reproduction

1992
Risk of spontaneous abortion in workers exposed to toluene.
    British journal of industrial medicine, 1992, Volume: 49, Issue:11

    Topics: Abortion, Spontaneous; Adult; Female; Humans; Maternal Age; Occupational Exposure; Parity; Pregnancy

1992
Sex-, age- and pregnancy-induced changes in the metabolism of toluene and trichloroethylene in rat liver in relation to the regulation of cytochrome P450IIE1 and P450IIC11 content.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:3

    Topics: Aging; Analgesics; Animals; Antibodies, Monoclonal; Benzyl Alcohol; Benzyl Alcohols; Chloral Hydrate

1992
[The experimental transplacental passage of dimethylformamide and toluene].
    Akusherstvo i ginekologiia, 1991, Issue:11

    Topics: Administration, Inhalation; Animals; Chromatography, Gas; Dimethylformamide; Female; Fetus; Placenta

1991
Neurobehavioral development of rats exposed to toluene through maternal milk.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1991, Volume: 24, Issue:12

    Topics: Animals; Brain; Disease Models, Animal; Female; Milk; Pregnancy; Rats; Rats, Wistar; Toluene

1991
[Influence on benzene and toluene to reproductive function of female workers in leathershoe-making industry].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1991, Volume: 25, Issue:2

    Topics: Adult; Benzene; China; Female; Humans; Menstruation Disturbances; Occupational Diseases; Pre-Eclamps

1991
Toluene abuse during pregnancy: obstetric complications and perinatal outcomes.
    Obstetrics and gynecology, 1991, Volume: 77, Issue:4

    Topics: Adult; Female; Follow-Up Studies; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Pregn

1991
Effects of toluene exposure during gestation on neurobehavioral development of rats and hamsters.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1990, Volume: 23, Issue:6-7

    Topics: Animals; Behavior, Animal; Body Weight; Cricetinae; Female; Litter Size; Male; Mesocricetus; Pregnan

1990
Developmental toxicity of in utero exposure to toluene on malnourished and well nourished rats.
    Toxicology, 1990, Volume: 64, Issue:2

    Topics: Animals; Animals, Newborn; Embryonic and Fetal Development; Female; Gestational Age; Injections, Sub

1990
Toluene embryopathy: two new cases.
    Journal of medical genetics, 1989, Volume: 26, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Child, Preschool; Developmental Disabilities; Female; Humans; In

1989
[Effect of small doses of toxic substances and noise on the reproductive function of young animals].
    Gigiena i sanitariia, 1989, Issue:10

    Topics: Animals; Benzene Derivatives; Dose-Response Relationship, Drug; Estrus; Female; Fetal Death; Fetal G

1989
[Effect of toluene inhalation in rats, mice, and mice offsprings].
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1988, Volume: 42, Issue:2

    Topics: Administration, Inhalation; Animals; Animals, Newborn; Brain; Catecholamines; Female; Growth Disorde

1988
[Effects of dibenzyltoluene on fetal developments of rats].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1988, Issue:106

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Dose-Response Relationship, Drug;

1988
Toluene abuse and renal tubular acidosis in pregnancy.
    Obstetrics and gynecology, 1988, Volume: 71, Issue:5

    Topics: Acidosis; Acidosis, Renal Tubular; Adult; Female; Fetal Growth Retardation; Hippurates; Humans; Infa

1988
[Hygienic standards for 2,4-dichlorotoluene in reservoir water].
    Gigiena i sanitariia, 1988, Issue:2

    Topics: Animals; Blood; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Male; Maximum Allowable Co

1988
Chemical exposures at work in early pregnancy and congenital defect: a case-referent study.
    British journal of industrial medicine, 1987, Volume: 44, Issue:8

    Topics: Abnormalities, Drug-Induced; Air Pollutants, Occupational; Digestive System Abnormalities; Female; H

1987
A perinatal study of toluene in CD-1 mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetus; Isoenzymes; L-Lactate Dehydrogenase; Mice; Preg

1986
Placental transfer and distribution of toluene, xylene and benzene, and their metabolites during gestation in mice.
    Biological research in pregnancy and perinatology, 1986, Volume: 7, Issue:3

    Topics: Animals; Autoradiography; Benzene; Female; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Pregna

1986
Learning impairment in rats following low-level toluene exposure during brain development--a comparative study of high avoidance rats and Wistar rats.
    Industrial health, 1986, Volume: 24, Issue:4

    Topics: Animals; Female; Learning Disabilities; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, In

1986
The possible contribution of industrial chemicals (organic solvents) to the incidence of congenital defects caused by teratogenic drugs and consumer goods--an experimental study.
    Progress in clinical and biological research, 1985, Volume: 163B

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Benzene; Drug Synergism; Ethanol; Female; Fetus; Preg

1985
Toluene embryopathy.
    The Journal of pediatrics, 1985, Volume: 106, Issue:6

    Topics: Abnormalities, Drug-Induced; Child, Preschool; Environmental Pollution; Female; Growth Disorders; Hu

1985
Comparison of NCS solubilization and a wet combustion technique for 14 C measurement in dried biological tissues.
    Analytical biochemistry, 1973, Volume: 53, Issue:1

    Topics: Animals; Brain Chemistry; Carbaryl; Carbon Isotopes; Female; Fetus; Hot Temperature; Kidney; Liver;

1973
Learning deficits in 4 weeks old offspring of the nursing mothers treated with the neuroleptic drug penfluridol.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Avoidance Learning; Body Weight; Breast Feeding; Female; Glu

1973
Regional changes in monoamine levels and in the rate of tyrosine and tryptophan hydroxylation in 4 week old offspring of nursing mothers treated with the neuroleptic drug penfluridol.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:4

    Topics: 5-Hydroxytryptophan; Age Factors; Animals; Animals, Newborn; Biogenic Amines; Body Weight; Brain; Br

1974
Whole body autoradiographic studies on the distribution of 3-H-labeled penfluridol (3-H-TLP-607) in mice and rats.
    Chemical & pharmaceutical bulletin, 1974, Volume: 22, Issue:9

    Topics: Animals; Autoradiography; Female; Hydrocarbons, Halogenated; Injections, Intravenous; Male; Mice; Pi

1974
Transfer across perfused human placenta. 3. Effect of chain length on transfer of free fatty acids.
    Pediatric research, 1974, Volume: 8, Issue:9

    Topics: Antipyrine; Caproates; Caprylates; Carbon Radioisotopes; Chromatography, Thin Layer; Colorimetry; Fa

1974
[Study of the embryotoxic and teratogenic effect of several industrial substances formed during the production of dimethylterephthalate].
    Gigiena truda i professional'nye zabolevaniia, 1972, Volume: 16, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Occupational Medicine; Phthalic Aci

1972
Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus.
    Toxicon : official journal of the International Society on Toxinology, 1972, Volume: 10, Issue:4

    Topics: Animals; Atropine; Chlorpheniramine; Cocaine; Diphenhydramine; Estrus; Female; Hexamethonium Compoun

1972
The contribution of prostaglandin production to contractions of the isolated uterus of the rat.
    British journal of pharmacology, 1973, Volume: 48, Issue:4

    Topics: Animals; Chromatography, Gas; Ducks; Epinephrine; Female; In Vitro Techniques; Indomethacin; Muscle

1973
Radioimmunoassay of aldosterone in plasma and urine: validation of a novel separation technique and a rapid urine assay.
    Clinical science and molecular medicine, 1973, Volume: 45, Issue:5

    Topics: Aldosterone; Animals; Chromatography, Paper; Cross Reactions; Female; Furosemide; Humans; Hydrocorti

1973
[Autoradiographic studies on the distribution of 14 C-labelled Bisolvon in the rat and mouse].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:7

    Topics: Aniline Compounds; Animals; Autoradiography; Carbon Isotopes; Expectorants; Female; Male; Maternal-F

1971
Estimation of total estrogens in early pregnancy by column chromatography.
    Steroids, 1971, Volume: 18, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Alcohols; Androsterone; Autoanalysis; Cholesterol; Chrom

1971
Persistence of Phosvel in corn silage and effects of feeding dairy cows the treated silage.
    Journal of dairy science, 1971, Volume: 54, Issue:12

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cattle; Cholinesteras

1971
[Transplacental effect of blastomogenic substances. Some further studies on organ cultures].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:7

    Topics: Adenoma; Animals; Benz(a)Anthracenes; Biphenyl Compounds; Carcinogens; Culture Techniques; Embryo, M

1969
[The combined effect of divinyl and toluol on the estrus cycle in rats].
    Akusherstvo i ginekologiia, 1969, Volume: 45, Issue:9

    Topics: Animals; Estrus; Female; Polyvinyls; Pregnancy; Rats; Toluene

1969
A method for the estimation of pregnanediol in amniotic fluid.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1970, Volume: 77, Issue:6

    Topics: 17-Ketosteroids; Acids; Amniotic Fluid; Chromatography; Chromatography, Gas; Female; Humans; Methods

1970
[A simple, new colorimetric method for the determination of pregnanediol].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1970, Volume: 8, Issue:6

    Topics: Abortion, Threatened; Chemistry, Clinical; Colorimetry; Female; Flavoring Agents; Glucuronates; Huma

1970
[Animal experimental studies of an industrial noxa].
    Archiv fur Gynakologie, 1967, Volume: 204, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Animals; Female; Humans; Infant, Newbor

1967