toluene has been researched along with Nerve Degeneration in 12 studies
methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| " By day 1, and extending through 4 days following kainic acid-induced seizures, brains from DNA-PKcs null mice showed widespread neurodegeneration that encompassed the entire hippocampal CA1-CA3 pyramidal cell layer, entorhinal cortex, and lateral septum, with relative sparing of the dentate gyrus granule cell layer and hilus, as judged by toluidine blue, Fluoro-Jade B, and terminal dUTP nick end labeling staining." | 7.73 | DNA damage and nonhomologous end joining in excitotoxicity: neuroprotective role of DNA-PKcs in kainic acid-induced seizures. ( Chechlacz, M; Gilliams-Francis, K; Lamonica, K; Lin, SL; Liu, J; Naegele, JR; Navarro-Quiroga, I; Neema, M, 2005) |
| " By day 1, and extending through 4 days following kainic acid-induced seizures, brains from DNA-PKcs null mice showed widespread neurodegeneration that encompassed the entire hippocampal CA1-CA3 pyramidal cell layer, entorhinal cortex, and lateral septum, with relative sparing of the dentate gyrus granule cell layer and hilus, as judged by toluidine blue, Fluoro-Jade B, and terminal dUTP nick end labeling staining." | 3.73 | DNA damage and nonhomologous end joining in excitotoxicity: neuroprotective role of DNA-PKcs in kainic acid-induced seizures. ( Chechlacz, M; Gilliams-Francis, K; Lamonica, K; Lin, SL; Liu, J; Naegele, JR; Navarro-Quiroga, I; Neema, M, 2005) |
| "Rats were subjected to seizures induced by kainic acid, and the resulting changes in CNS zinc staining were studied with the toluene sulfonamide quinoline fluorescence method." | 3.67 | Translocation of zinc may contribute to seizure-induced death of neurons. ( Frederickson, CJ; Hernandez, MD; McGinty, JF, 1989) |
| "Toluene treatment was performed by inhalation of 3,000 ppm toluene, in a 8 h/day and 6 day/week order for 12 weeks." | 1.35 | Nigella sativa and derived thymoquinone prevents hippocampal neurodegeneration after chronic toluene exposure in rats. ( Kanter, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pitts, A | 1 |
| Dailey, K | 1 |
| Newington, JT | 1 |
| Chien, A | 1 |
| Arseneault, R | 1 |
| Cann, T | 1 |
| Thompson, LM | 1 |
| Cumming, RC | 1 |
| Fujiwara, T | 1 |
| Morimoto, K | 1 |
| Ladefoged, O | 2 |
| Hougaard, KS | 2 |
| Hass, U | 2 |
| Sørensen, IK | 1 |
| Lund, SP | 1 |
| Svendsen, GW | 1 |
| Lam, HR | 1 |
| Neema, M | 1 |
| Navarro-Quiroga, I | 1 |
| Chechlacz, M | 1 |
| Gilliams-Francis, K | 1 |
| Liu, J | 1 |
| Lamonica, K | 1 |
| Lin, SL | 1 |
| Naegele, JR | 1 |
| Liang, ZQ | 1 |
| Li, YL | 1 |
| Zhao, XL | 1 |
| Han, R | 1 |
| Wang, XX | 1 |
| Wang, Y | 1 |
| Chase, TN | 1 |
| Bennett, MC | 1 |
| Qin, ZH | 1 |
| Eve, DJ | 1 |
| Dennis, JS | 1 |
| Citron, BA | 1 |
| Plesnila, N | 1 |
| von Baumgarten, L | 1 |
| Retiounskaia, M | 1 |
| Engel, D | 1 |
| Ardeshiri, A | 1 |
| Zimmermann, R | 1 |
| Hoffmann, F | 1 |
| Landshamer, S | 1 |
| Wagner, E | 1 |
| Culmsee, C | 1 |
| Kanter, M | 1 |
| Saavedra, H | 1 |
| De Marinis, A | 1 |
| Palestini, M | 1 |
| Dalgaard, M | 1 |
| Hossaini, A | 1 |
| Frederickson, CJ | 1 |
| Hernandez, MD | 1 |
| McGinty, JF | 1 |
| Caramia, F | 1 |
| Ubaldo Angeletti, P | 1 |
| Levi-Montalcini, R | 1 |
| Carratelli, L | 1 |
12 other studies available for toluene and Nerve Degeneration
| Article | Year |
|---|---|
Dithiol-based compounds maintain expression of antioxidant protein peroxiredoxin 1 that counteracts toxicity of mutant huntingtin.
Topics: Animals; Cell Death; Cell Line, Transformed; Corpus Striatum; Disulfides; Huntingtin Protein; Huntin | 2012 |
Inhibition of p53 transactivation functionally interacts with microtubule stabilization to suppress excitotoxicity-induced axon degeneration.
Topics: Animals; Axons; Benzothiazoles; Cells, Cultured; Dynactin Complex; Glutamic Acid; Hippocampus; Micro | 2012 |
Effects of combined prenatal stress and toluene exposure on apoptotic neurodegeneration in cerebellum and hippocampus of rats.
Topics: Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; Caspases; Cerebellum; Embryonic and Fetal De | 2004 |
DNA damage and nonhomologous end joining in excitotoxicity: neuroprotective role of DNA-PKcs in kainic acid-induced seizures.
Topics: Animals; Benzothiazoles; Cell Death; Cells, Cultured; DNA Damage; DNA Repair; DNA-Activated Protein | 2005 |
NF-kappaB contributes to 6-hydroxydopamine-induced apoptosis of nigral dopaminergic neurons through p53.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Benzothiazoles; DNA Fragmentation; Dopamine; Mal | 2007 |
Transcription factor p53 in degenerating spinal cords.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Behavior, Animal; Benzothiazoles; Case-Control | 2007 |
Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kappaB transcriptional activity.
Topics: Animals; Apoptosis; Benzothiazoles; Brain Injuries; Disease Models, Animal; Female; Humans; Male; Mi | 2007 |
Nigella sativa and derived thymoquinone prevents hippocampal neurodegeneration after chronic toluene exposure in rats.
Topics: Animals; Benzoquinones; Hippocampus; Immunohistochemistry; Male; Microscopy, Electron; Nerve Degener | 2008 |
Neuronal changes induced by chronic toluene exposure in the cat.
Topics: Administration, Inhalation; Animals; Behavior, Animal; Cats; Cerebellum; Cerebral Cortex; Electrophy | 1996 |
Developmental toxicity of toluene in male rats: effects on semen quality, testis morphology, and apoptotic neurodegeneration.
Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Animals; Animals, Newborn; Apoptosis; Body | 2001 |
Translocation of zinc may contribute to seizure-induced death of neurons.
Topics: Amygdala; Animals; Cell Survival; Cerebellum; Hippocampus; In Vitro Techniques; Kainic Acid; Nerve D | 1989 |
Mitochondrial lesions of developing sympathetic neurons induced by bretylium tosylate.
Topics: Animals; Animals, Newborn; Bretylium Compounds; Dopamine; Ganglia, Autonomic; Guanethidine; Microsco | 1972 |