toluene has been researched along with Huntington Disease in 2 studies
methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ehrnhoefer, DE | 1 |
| Skotte, NH | 1 |
| Ladha, S | 1 |
| Nguyen, YT | 1 |
| Qiu, X | 1 |
| Deng, Y | 1 |
| Huynh, KT | 1 |
| Engemann, S | 1 |
| Nielsen, SM | 1 |
| Becanovic, K | 1 |
| Leavitt, BR | 1 |
| Hasholt, L | 1 |
| Hayden, MR | 1 |
| Pitts, A | 1 |
| Dailey, K | 1 |
| Newington, JT | 1 |
| Chien, A | 1 |
| Arseneault, R | 1 |
| Cann, T | 1 |
| Thompson, LM | 1 |
| Cumming, RC | 1 |
2 other studies available for toluene and Huntington Disease
| Article | Year |
|---|---|
p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin.
Topics: Animals; Benzothiazoles; Caspase 6; Cells, Cultured; Disease Models, Animal; Female; Fibroblasts; Hu | 2014 |
Dithiol-based compounds maintain expression of antioxidant protein peroxiredoxin 1 that counteracts toxicity of mutant huntingtin.
Topics: Animals; Cell Death; Cell Line, Transformed; Corpus Striatum; Disulfides; Huntingtin Protein; Huntin | 2012 |