Page last updated: 2024-10-20

toluene and Glue Abuse

toluene has been researched along with Glue Abuse in 30 studies

methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.

Research Excerpts

ExcerptRelevanceReference
"Toluene sniffing, frequently described under the generic category of "glue sniffing," is a potential cause of normal anion gap metabolic acidosis due to distal renal tubular acidosis."7.79Metabolic acidosis in toluene sniffing. ( Rehman, H; Tuchscherer, J, 2013)
"Toluene is an aromatic hydrocarbon with widespread industrial use as an organic solvent."5.37Atrioventricular conduction abnormality and hyperchloremic metabolic acidosis in toluene sniffing. ( Chern, CH; How, CK; Hu, YH; Huang, CI; Hung-Tsang Yen, D; Tsao, JH, 2011)
" Petrol sniffing significantly impaired height and weight and was associated with meeting 'failure to thrive' criteria; growth diagnostically out-performed serum toluene."3.85Adolescent inhalant abuse leads to other drug use and impaired growth; implications for diagnosis. ( Cairney, S; Crossin, R; Duncan, JR; Lawrence, AJ, 2017)
"Toluene sniffing, frequently described under the generic category of "glue sniffing," is a potential cause of normal anion gap metabolic acidosis due to distal renal tubular acidosis."3.79Metabolic acidosis in toluene sniffing. ( Rehman, H; Tuchscherer, J, 2013)
"Toluene exposure was negatively associated with body weight ( d = -0."2.61Growth changes after inhalant abuse and toluene exposure: A systematic review and meta-analysis of human and animal studies. ( Andrews, ZB; Churilov, L; Crossin, R; Duncan, JR; Lawrence, AJ, 2019)
"Inhalant abuse is most common during adolescence and can result in cognitive impairments during an important maturational period."1.62Adolescent chronic intermittent toluene inhalation dynamically regulates the transcriptome and neuronal methylome within the rat medial prefrontal cortex. ( Baker-Andresen, D; Bredy, TW; Crossin, R; Dick, ALW; Duncan, JR; Edson, J; Lawrence, AJ; Li, X; Marshall, V; Roeh, S; Zhao, Q, 2021)
"Toluene has a complex mechanism of action and broad behavioral effects, among which memory impairment is reported consistently."1.56Minocycline prevents neuronal hyperexcitability and neuroinflammation in medial prefrontal cortex, as well as memory impairment caused by repeated toluene inhalation in adolescent rats. ( Armenta-Reséndiz, M; Carranza-Aguilar, CJ; Cruz, SL; Galván, EJ, 2020)
"Toluene-induced CPP was associated with increased excitability of IL5/6 mPFC neurons projecting to the core of the NAc and reduced excitability of those projecting to the NAc shell."1.48Chemogenetic Excitation of Accumbens-Projecting Infralimbic Cortical Neurons Blocks Toluene-Induced Conditioned Place Preference. ( Wayman, WN; Woodward, JJ, 2018)
"Turk J Pediatr 2018; 60: 206-209."1.48A `glue sniffer` teenager with anuric renal failure and hepatitis. ( Karapınar, B; Saz, EU; Türksoylu, M; Yazıcı, P; Yurtseven, A, 2018)
"Toluene inhalation is a common form of drug abuse throughout the world."1.38Clinical presentation and management in acute toluene intoxication: a case series. ( Cámara-Lemarroy, CR; González-González, JG; Gónzalez-Moreno, EI; Rodriguez-Gutierrez, R, 2012)
"Toluene is a commonly used solvent in the rubber, paint, plastics, leather, printing, and chemical industries."1.371H NMR spectroscopic identification of a glue sniffing biomarker. ( Kim, MD; Kim, S; Kwon, B; Lee, DK; Lee, JS; Park, YJ, 2011)
"Toluene is an aromatic hydrocarbon with widespread industrial use as an organic solvent."1.37Atrioventricular conduction abnormality and hyperchloremic metabolic acidosis in toluene sniffing. ( Chern, CH; How, CK; Hu, YH; Huang, CI; Hung-Tsang Yen, D; Tsao, JH, 2011)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's25 (83.33)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
Cruz, SL3
Armenta-Reséndiz, M1
Carranza-Aguilar, CJ1
Galván, EJ1
Dick, ALW1
Zhao, Q1
Crossin, R5
Baker-Andresen, D1
Li, X1
Edson, J1
Roeh, S1
Marshall, V1
Bredy, TW1
Lawrence, AJ5
Duncan, JR5
Arunogiri, S1
Lau, YH1
Mawardi, AS1
Zain, NR1
Viswanathan, S1
Wayman, WN1
Woodward, JJ2
Andrews, ZB2
Churilov, L1
Sims, NA1
Pang, T1
Mathai, M1
Gooi, JH1
Stefanidis, A1
Oldfield, BJ1
Yurtseven, A1
Türksoylu, M1
Yazıcı, P1
Karapınar, B1
Saz, EU1
Hsu, CC1
Haacke, EM1
Heyn, C1
Kato, K1
Watkins, TW1
Krings, T1
Filley, CM1
Tuchscherer, J1
Rehman, H1
Palmer, BF1
Perazella, MA1
Choi, MJ1
Senthilkumaran, S1
Jena, NN1
Jayaraman, S1
Menezes, RG1
Thirumalaikolundusubramanian, P1
Beckley, JT1
Randall, PK1
Smith, RJ1
Hughes, BA1
Kalivas, PW1
Jayanth, SH1
Hugar, BS1
Praveen, S1
Girish Chandra, YP1
Cairney, S1
Kwon, B1
Kim, S3
Lee, DK1
Park, YJ1
Kim, MD1
Lee, JS1
Elkoussi, A1
Bakheet, S1
Hynes-Dowell, M1
Mateu-Gelabert, P1
Barros, HM1
Delva, J1
Villatoro, JA1
Ortiz, A1
Medina-Mora, ME1
Sharma, S1
Lal, R1
Važan, P1
Khan, MR1
Poduška, O1
Stastná, L1
Miovský, M1
Domínguez, M1
Takagi, M1
Lubman, DI1
Yücel, M1
Chen, HH1
Lin, YR1
Chan, MH1
Tsao, JH1
Hu, YH1
How, CK1
Chern, CH1
Hung-Tsang Yen, D1
Huang, CI1
Cámara-Lemarroy, CR1
Gónzalez-Moreno, EI1
Rodriguez-Gutierrez, R1
González-González, JG1
Pan, SY1
Lin, SL1
DODDS, J1
SANTOSTEFANO, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neurobiología Del Consumo de Substancias Psicoactivas: PET-CT- Inhalables[NCT02188914]70 participants (Actual)Observational2014-11-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for toluene and Glue Abuse

ArticleYear
Harms associated with inhalant misuse in adolescent females - a review of the pre-clinical and clinical evidence.
    Drug and alcohol dependence, 2020, 11-01, Volume: 216

    Topics: Administration, Inhalation; Adolescent; Female; Humans; Inhalant Abuse; Substance-Related Disorders;

2020
Growth changes after inhalant abuse and toluene exposure: A systematic review and meta-analysis of human and animal studies.
    Human & experimental toxicology, 2019, Volume: 38, Issue:2

    Topics: Animals; Body Height; Body Weight; Humans; Inhalant Abuse; Solvents; Toluene

2019
Toluene abuse and white matter: a model of toxic leukoencephalopathy.
    The Psychiatric clinics of North America, 2013, Volume: 36, Issue:2

    Topics: Atrophy; Brain; Dementia; Humans; Inhalant Abuse; Leukoencephalopathies; Nerve Fibers, Myelinated; P

2013
Conventional concepts and new perspectives for understanding the addictive properties of inhalants.
    Journal of pharmacological sciences, 2013, Volume: 122, Issue:4

    Topics: Adolescent; Animals; Brain; Dopaminergic Neurons; GABAergic Neurons; gamma-Aminobutyric Acid; Glutam

2013

Other Studies

26 other studies available for toluene and Glue Abuse

ArticleYear
Minocycline prevents neuronal hyperexcitability and neuroinflammation in medial prefrontal cortex, as well as memory impairment caused by repeated toluene inhalation in adolescent rats.
    Toxicology and applied pharmacology, 2020, 05-15, Volume: 395

    Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Gene Expression; Inhalant Abuse; Inte

2020
Adolescent chronic intermittent toluene inhalation dynamically regulates the transcriptome and neuronal methylome within the rat medial prefrontal cortex.
    Addiction biology, 2021, Volume: 26, Issue:3

    Topics: Administration, Inhalation; Animals; DNA Methylation; DNA-Binding Proteins; Gene Expression; Inhalan

2021
Toluene-induced leukodystrophy from glue sniffing.
    Practical neurology, 2021, Volume: 21, Issue:5

    Topics: Adult; Basal Ganglia; Brain; Humans; Inhalant Abuse; Male; Substance-Related Disorders; Toluene

2021
Chemogenetic Excitation of Accumbens-Projecting Infralimbic Cortical Neurons Blocks Toluene-Induced Conditioned Place Preference.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018, 02-07, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Aging; Animals; Cerebral Cortex; Conditioning, Operant; Drug-Seeking Beh

2018
Adolescent Inhalant Abuse Results in Adrenal Dysfunction and a Hypermetabolic Phenotype with Persistent Growth Impairments.
    Neuroendocrinology, 2018, Volume: 107, Issue:4

    Topics: Adolescent; Adolescent Behavior; Adolescent Development; Adrenal Gland Diseases; Adrenal Glands; Ani

2018
A `glue sniffer` teenager with anuric renal failure and hepatitis.
    The Turkish journal of pediatrics, 2018, Volume: 60, Issue:2

    Topics: Acute Kidney Injury; Adhesives; Administration, Inhalation; Adolescent; Chemical and Drug Induced Li

2018
"Pseudo" T1-weighted appearance of the brain on FLAIR: unmasking the extent of gray matter involvement on susceptibility-weighted imaging in chronic toluene abuse.
    Neuroradiology, 2019, Volume: 61, Issue:1

    Topics: Chronic Disease; Female; Gray Matter; Humans; Inhalant Abuse; Leukoencephalopathies; Magnetic Resona

2019
Metabolic acidosis in toluene sniffing.
    CJEM, 2013, Volume: 15, Issue:4

    Topics: Acidosis; Acidosis, Renal Tubular; Adult; Emergency Service, Hospital; Female; Humans; Inhalant Abus

2013
American Society of Nephrology Quiz and Questionnaire 2013: electrolyte and acid-base.
    Clinical journal of the American Society of Nephrology : CJASN, 2014, Jun-06, Volume: 9, Issue:6

    Topics: Acid-Base Equilibrium; Acidosis; Education, Medical, Continuing; Female; Humans; Hypokalemia; Hypona

2014
Direct urine ammonium measurement in metabolic acidosis: time to move on.
    CJEM, 2014, Volume: 16, Issue:6

    Topics: Acidosis; Acidosis, Renal Tubular; Female; Humans; Inhalant Abuse; Solvents; Toluene

2014
Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene.
    Addiction biology, 2016, Volume: 21, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enkephalins; Glutamic Acid; Immun

2016
Glue sniffing.
    The Medico-legal journal, 2017, Volume: 85, Issue:1

    Topics: Forensic Medicine; Humans; Inhalant Abuse; Male; Substance-Related Disorders; Toluene; Young Adult

2017
Adolescent inhalant abuse leads to other drug use and impaired growth; implications for diagnosis.
    Australian and New Zealand journal of public health, 2017, Volume: 41, Issue:1

    Topics: Adolescent; Adolescent Behavior; Creatine Kinase; Failure to Thrive; Gasoline; Growth Disorders; Hum

2017
1H NMR spectroscopic identification of a glue sniffing biomarker.
    Forensic science international, 2011, Jun-15, Volume: 209, Issue:1-3

    Topics: Biomarkers; Case-Control Studies; Citrates; Creatinine; Forensic Toxicology; Hippurates; Humans; Inh

2011
Volatile substance misuse among street children in Upper Egypt.
    Substance use & misuse, 2011, Volume: 46 Suppl 1

    Topics: Adolescent; Child; Egypt; Female; Homeless Youth; Humans; Inhalant Abuse; Male; Pilot Projects; Solv

2011
Volatile substance misuse among high school students in South America.
    Substance use & misuse, 2011, Volume: 46 Suppl 1

    Topics: Adolescent; Cross-Sectional Studies; Female; Humans; Inhalant Abuse; Male; Multivariate Analysis; So

2011
Volatile substance misuse in Mexico: correlates and trends.
    Substance use & misuse, 2011, Volume: 46 Suppl 1

    Topics: Adolescent; Adult; Aged; Child; Female; Humans; Inhalant Abuse; Male; Mexico; Middle Aged; Solvents;

2011
Volatile substance misuse among street children in India: a preliminary report.
    Substance use & misuse, 2011, Volume: 46 Suppl 1

    Topics: Adolescent; Child; Female; Homeless Youth; Humans; India; Inhalant Abuse; Male; Risk Factors; Solven

2011
Chronic toluene misuse among Roma youth in Eastern Slovakia.
    Substance use & misuse, 2011, Volume: 46 Suppl 1

    Topics: Adolescent; Adult; Child; Female; Humans; Inhalant Abuse; Interviews as Topic; Male; Roma; Slovakia;

2011
Misusing volatile substances for their hallucinatory effects: a qualitative pilot study with Mexican teenagers and a pharmacological discussion of their hallucinations.
    Substance use & misuse, 2011, Volume: 46 Suppl 1

    Topics: Adolescent; Female; Hallucinations; Humans; Inhalant Abuse; Interviews as Topic; Male; Mexico; Pilot

2011
Solvent-induced leukoencephalopathy: a disorder of adolescence?
    Substance use & misuse, 2011, Volume: 46 Suppl 1

    Topics: Adolescent; Autopsy; Brain; Humans; Inhalant Abuse; Leukoencephalopathies; Radiography; Solvents; To

2011
Toluene exposure during brain growth spurt and adolescence produces differential effects on N-methyl-D-aspartate receptor-mediated currents in rat hippocampus.
    Toxicology letters, 2011, Sep-10, Volume: 205, Issue:3

    Topics: Aging; Animals; CA1 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Agonists; Excit

2011
Atrioventricular conduction abnormality and hyperchloremic metabolic acidosis in toluene sniffing.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2011, Volume: 110, Issue:10

    Topics: Acidosis; Adult; Atrioventricular Block; Chlorine; Humans; Inhalant Abuse; Male; Toluene

2011
Clinical presentation and management in acute toluene intoxication: a case series.
    Inhalation toxicology, 2012, Volume: 24, Issue:7

    Topics: Acidosis; Adolescent; Adult; Female; Humans; Hypokalemia; Inhalant Abuse; Male; Muscle Weakness; Par

2012
Toluene intoxication-atrioventricular block due to hypokalemia?
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2012, Volume: 111, Issue:9

    Topics: Acidosis; Atrioventricular Block; Humans; Inhalant Abuse; Male; Toluene

2012
A COMPARISON OF THE COGNITIVE FUNCTIONING OF GLUE-SNIFFERS AND NONSNIFFERS.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: Adhesives; Adolescent; Attention; Child; Cognition; Humans; Inhalant Abuse; Motor Skills; Nervous Sy

1964