Page last updated: 2024-10-20

toluene and Experimental Neoplasms

toluene has been researched along with Experimental Neoplasms in 44 studies

methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.

Research Excerpts

ExcerptRelevanceReference
"Pancreatic cancer is an exceedingly lethal disease with a five-year survival that ranks among the lowest of gastrointestinal malignancies."1.38Evidence for activation of mutated p53 by apigenin in human pancreatic cancer. ( Chen, M; Eibl, G; Go, VL; Hines, OJ; King, JC; Li, G; Lu, QY; Moro, A; Reber, HA; Takahashi, H, 2012)
"Incidence of skin cancers was 58% for BAC, 15% for BYC and 10% for BOC within 560 days."1.26Carcinogenicity of benzyl chloride, benzal chloride, benzotrichloride and benzoyl chloride in mice by skin application. ( Fukuda, K; Matsushita, H; Sakabe, H; Takemoto, K, 1981)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199030 (68.18)18.7374
1990's7 (15.91)18.2507
2000's5 (11.36)29.6817
2010's2 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tye, R1
Stemmer, KL2
Onuma, K1
Suenaga, Y1
Sakaki, R1
Yoshitome, S1
Sato, Y1
Ogawara, S1
Suzuki, S1
Kuramitsu, Y1
Yokoyama, H1
Murakami, A1
Hamada, J1
Nicolson, GL1
Kobayashi, M1
Fujii, J1
Okada, F1
King, JC1
Lu, QY1
Li, G1
Moro, A1
Takahashi, H1
Chen, M1
Go, VL1
Reber, HA1
Eibl, G1
Hines, OJ1
Dunnick, JK1
Burka, LT1
Mahler, J1
Sills, R1
UMEDA, M2
SHELTON, E1
NEMETH, G1
MASSZI, F1
SELLEI, C1
GEL'SHTEIN, VI1
BELITSKY, GA1
VASILIEV, JM1
SIMMERS, MH1
GELSHTEIN, VI1
IAGORSKAIA, TA2
Bingham, E1
Falk, HL1
Daoud, AH1
Griffin, AC1
Fukuda, K1
Matsushita, H1
Sakabe, H1
Takemoto, K1
Hooson, J1
Hicks, RM1
Grasso, P1
Chowaniec, J1
Burns, LA2
Bradley, SG2
White, KL2
McCay, JA2
Fuchs, BA2
Stern, M2
Brown, RD2
Musgrove, DL2
Holsapple, MP2
Luster, MI2
Capó, MA1
Frejo, MT1
Sevil, B1
Maltoni, C2
Ciliberti, A1
Pinto, C1
Soffritti, M1
Belpoggi, F2
Menarini, L1
Stadler, P1
Grosu, AL1
Molls, M1
Conti, B1
Cotti, G1
Fiala, S1
Fiala, ES1
Korosteleva, TA1
Potapenkova, LS2
Golub', NI1
Kolesnichenko, TS1
Shabad, LM1
Takemura, T2
Akamatsu, Y1
Ikegami, R1
Takahashi, A1
Miyajima, H1
Müller, M2
Louis, CJ1
Blunck, JM1
Pliss, GB2
Dzhioev, FK1
Broitman, AIa1
Dobre, V1
Maltezeanu, G1
Frei, JV1
Stephens, P1

Reviews

4 reviews available for toluene and Experimental Neoplasms

ArticleYear
alpha-Chlorinated toluenes and benzoyl chloride.
    IARC monographs on the evaluation of carcinogenic risks to humans, 1999, Volume: 71 Pt 2

    Topics: Animals; Benzoates; Benzyl Compounds; Carcinogenicity Tests; Carcinogens; Humans; Mutagenicity Tests

1999
Toluene.
    IARC monographs on the evaluation of carcinogenic risks to humans, 1999, Volume: 71 Pt 2

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Humans; Mutagenicity Tests; Mutagens; Neoplasms; Neopla

1999
Toluene diisocyanates.
    IARC monographs on the evaluation of carcinogenic risks to humans, 1999, Volume: 71 Pt 2

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Humans; Isocyanates; Mutagenicity Tests; Mutagens; Neop

1999
5-Chloro-ortho-toluidine.
    IARC monographs on the evaluation of carcinogenic risks to humans, 2000, Volume: 77

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Coloring Agents; Disease Models, Animal; Environmental

2000

Other Studies

40 other studies available for toluene and Experimental Neoplasms

ArticleYear
Experimental carcinogenesis of the lung. II. Influence of phenols in the production of carcinoma.
    Journal of the National Cancer Institute, 1967, Volume: 39, Issue:2

    Topics: Adenocarcinoma; Adenoma; Aerosols; Animals; Benzo(a)pyrene; Bronchial Neoplasms; Carcinogens; Enviro

1967
Development of a quantitative bioassay to assess preventive compounds against inflammation-based carcinogenesis.
    Nitric oxide : biology and chemistry, 2011, Aug-01, Volume: 25, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Biological Assay; Cell Adhesion; Coumarins; Endothelial Cells; Fem

2011
Evidence for activation of mutated p53 by apigenin in human pancreatic cancer.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:2

    Topics: Animals; Apigenin; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Benzothiazoles; Cell Lin

2012
Toxicology and carcinogenesis studies of p-nitrotoluene (CAS no. 99-99-0) in F344/N rats and B6C3F(1) mice (feed studies).
    National Toxicology Program technical report series, 2002, Issue:498

    Topics: Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; CHO Cells; Cricetinae; Diet; Dose

2002
Carcinogenic potential of o-nitrotoluene and p-nitrotoluene.
    Toxicology, 2003, Feb-01, Volume: 183, Issue:1-3

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Male; Mice; Neoplasms, Experimental; Rats; Rats, Inbred

2003
[Experimental carcinogenesis: rat rhabdomyosarcoma produced by the injection of toluylene blue].
    Gan, 1954, Volume: 45, Issue:2-3

    Topics: Animals; Carcinogenesis; Neoplasms, Experimental; Rats; Rhabdomyosarcoma; Toluene

1954
Hepatomas in mice. I. Factors affecting the rapid induction of a high incidence of hepatomas by o-aminoazotoluene.
    Journal of the National Cancer Institute, 1955, Volume: 16, Issue:1

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Incidence; Liver Neoplasms; Liver Neoplasms, Experi

1955
[Experimental studies on trinitrotoluol and butter yellow; production of precancer with trinitrotoluol].
    Kiserletes orvostudomany, 1955, Volume: 7, Issue:4

    Topics: Animals; Carcinogens; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Toluene

1955
[Experimental study of m-toluylenediamine as carcinogenic agents].
    Gan, 1956, Volume: 47, Issue:3-4

    Topics: Animals; Carcinogens; Neoplasms, Experimental; Toluene

1956
[Appearance of tumors in the offspring of mice exposed to the effect of o-aminoazotoluene].
    Voprosy onkologii, 1961, Volume: 7(10)

    Topics: Animals; Azo Compounds; Mice; Neoplasms; Neoplasms, Experimental; o-Aminoazotoluene; Toluene

1961
EFFECTS OF SEX HORMONES ON THE EXCRETION OF BLASTOMOGENIC AZO-DYE IN MICE.
    Acta - Unio Internationalis Contra Cancrum, 1963, Volume: 19

    Topics: Androgens; Animals; Azo Compounds; Carcinoma, Hepatocellular; Castration; Colorimetry; Coloring Agen

1963
THE ROLE OF THE CHANGES ON THE MICROENVIRONMENT OF EPITHELIAL AND CONNECTIVE-TISSUE CELLS IN THE CARCINOGENESIS.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Azo Compounds; Benz(a)Anthracenes; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Cell Divi

1964
CANCERS FROM AIR-REFINED AND STEAM-REFINED ASPHALT.
    Industrial medicine & surgery, 1965, Volume: 34

    Topics: Animals; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Hydrocarbons; Injections, Subcutaneous; L

1965
[EFFECT OF O-AMINOAZOTOLUENE ON EXPLANTED NORMAL MOUSE LIVER AND ON TRANSPLANTED HEPATOMAS].
    Voprosy onkologii, 1964, Volume: 10

    Topics: Animals; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Mice; Neoplasm Transplantation; Neoplasm

1964
The effects of repeated injections of certain adjuvants on chemical carcinogenesis.
    Annals of allergy, 1967, Volume: 25, Issue:12

    Topics: Adjuvants, Immunologic; Animals; Benzopyrenes; Cyclohexanes; Female; Freund's Adjuvant; Granuloma; I

1967
Benzotrichloride.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1982, Volume: 29

    Topics: Animals; Carcinogens; Female; Humans; Hydrocarbons, Chlorinated; Mice; Mice, Inbred ICR; Mutagenicit

1982
Effect of retinoic acid, butylated hydroxytoluene, selenium and sorbic acid on azo-dye hepatocarcinogenesis.
    Cancer letters, 1980, Volume: 9, Issue:4

    Topics: Animals; Drug Interactions; Fatty Acids, Unsaturated; Liver Neoplasms; Male; Methyldimethylaminoazob

1980
Carcinogenicity of benzyl chloride, benzal chloride, benzotrichloride and benzoyl chloride in mice by skin application.
    Gan, 1981, Volume: 72, Issue:5

    Topics: Animals; Benzoates; Benzyl Compounds; Benzylidene Compounds; Female; Hydrocarbons, Chlorinated; Leuk

1981
Ortho-toluene sulphonamide and saccharin in the promotion of bladder cancer in the rat.
    British journal of cancer, 1980, Volume: 42, Issue:1

    Topics: Animals; Body Weight; Drinking; Eating; Female; Kidney; Methylnitrosourea; Neoplasms, Experimental;

1980
Immunotoxicity of mono-nitrotoluenes in female B6C3F1 mice: I. Para-nitrotoluene.
    Drug and chemical toxicology, 1994, Volume: 17, Issue:3

    Topics: Administration, Oral; Animals; Antigen-Antibody Reactions; Antigens; B-Lymphocytes; Body Weight; Bon

1994
Immunotoxicity of mono-nitrotoluenes in female B6C3F1 mice: II. Meta-nitrotoluene.
    Drug and chemical toxicology, 1994, Volume: 17, Issue:3

    Topics: Administration, Oral; Animals; Antibody Formation; Antigens; Blood Cells; Body Weight; Bone Marrow;

1994
The use of the glial fibrillary acidic protein (GFAP) biomarker as an early detection model of chemically induced cancer.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1997, Volume: 16, Issue:1

    Topics: Animals; Animals, Newborn; Astrocytes; Biomarkers, Tumor; Brain; Cell Division; Cell Line; Cell Tran

1997
Results of long-term experimental carcinogenicity studies of the effects of gasoline, correlated fuels, and major gasoline aromatics on rats.
    Annals of the New York Academy of Sciences, 1997, Dec-26, Volume: 837

    Topics: Animals; Benzene Derivatives; Biological Assay; Carcinogens; Female; Gasoline; Kerosene; Male; Mamma

1997
[A chemical inhibitor of p53 that protects mice from the side effects of cancer treatment].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2000, Volume: 176, Issue:2

    Topics: Animals; Antineoplastic Agents; Benzothiazoles; Combined Modality Therapy; Drug Evaluation, Preclini

2000
Toxicology and carcinogenesis studies of o-nitrotoluene sulfone (CAS no. 88-72-2) in F344/N rats and B6C3F(1) mice (feed studies).
    National Toxicology Program technical report series, 2002, Issue:504

    Topics: Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; CHO Cells; Cricetinae; Diet; Dose

2002
Experimental studies on benzene carcinogenicity at the Bologna Institute of Oncology: current results and ongoing research.
    American journal of industrial medicine, 1985, Volume: 7, Issue:5-6

    Topics: Animals; Benzene; Benzene Derivatives; Female; Male; Mice; Neoplasms, Experimental; Rats; Rats, Inbr

1985
Activation by chemical carcinogens of gamma-glutamyl transpeptidase in rat and mouse liver.
    Journal of the National Cancer Institute, 1973, Volume: 51, Issue:1

    Topics: Acetamides; Acyltransferases; Animals; Azo Compounds; Carcinogens; Carcinoma, Hepatocellular; Diet;

1973
[Antigens and antibodies, circulating in the blood at early stages of experimental hepatocarcinogenesis].
    Voprosy onkologii, 1973, Volume: 19, Issue:7

    Topics: Animals; Antibodies; Antigens; Azo Compounds; Carcinogens; Immunodiffusion; Immunoelectrophoresis; L

1973
[Blastomogenic effects of some azo-containing compounds on the progeny of test mice].
    Biulleten' eksperimental'noi biologii i meditsiny, 1974, Volume: 78, Issue:12

    Topics: Aniline Compounds; Animals; Azo Compounds; Benzidines; Carcinogens; Diethylamines; Female; Leukemia,

1974
Growth behavior of spontaneous hepatoma and OAT-induced hepatoma in mice.
    Medical journal of Osaka University, 1966, Volume: 16, Issue:4

    Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Liver Neoplasms; Mice; Neoplasms, Experimental;

1966
Growth behavior of hepatomas in o-aminoazotoluene-treated mice in comparison with spontaneous hepatomas.
    Gan, 1967, Volume: 58, Issue:4

    Topics: Animals; Autoradiography; Azo Compounds; Carcinogens; Carcinoma, Hepatocellular; Hemangioendotheliom

1967
[Immunologic cross experiments with o-aminoazotoluene hepatomas and a spontaneous liver tumor in mice].
    Archiv fur Geschwulstforschung, 1968, Volume: 31, Issue:4

    Topics: Animals; Antigens; Carcinogens; Carcinoma, Hepatocellular; Female; Injections, Intraperitoneal; Live

1968
[Experiments on the induction of transplantation immunity against o-aminoazotoluene-hepatomas in syngeneic Fl-hybrid mice].
    Archiv fur Geschwulstforschung, 1968, Volume: 31, Issue:3

    Topics: Animals; Antigens; Azo Compounds; Carcinoma, Hepatocellular; Histocompatibility; Liver Neoplasms; Mi

1968
The isolation of normal rat liver h proteins and the immunological reactions of mouse anti-rat liver h protein.
    Cancer research, 1970, Volume: 30, Issue:7

    Topics: Animals; Antibodies; Antibody Formation; Antibody Specificity; Antigen-Antibody Reactions; Antigens;

1970
[An electrophoretic analysis of the serum proteins and soluble liver proteins of mice during experimental hepatocarcinogenesis].
    Voprosy onkologii, 1971, Volume: 17, Issue:9

    Topics: Animals; Antigens; Antigens, Neoplasm; Azo Compounds; Blood Protein Electrophoresis; Carcinoma, Hepa

1971
[Inhibition of O-aminazotoluol induced tumors with antioxidants].
    Voprosy onkologii, 1974, Volume: 20, Issue:7

    Topics: Animals; Antioxidants; Azo Compounds; Carcinogens; Cresols; Female; Liver Neoplasms; Mice; Mice, Inb

1974
[Comparative study of the sensitivity of liver explants and transplantable hepatomas in mice to various chemical substances].
    Voprosy onkologii, 1967, Volume: 13, Issue:9

    Topics: Animals; Azo Compounds; Benzopyrenes; Carcinogens; Fluorenes; Liver; Mice; Neoplasm Transplantation;

1967
3-N,N-bis(2-chloroethylamino)p-toluic acid, a new cytostatic drug active in cancer.
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:5

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Benzoates; Dosage Forms; Female; Hematopoiesis; M

1970
The correlation of promotion of tumour growth and of induction of hyperplasia in epidermal two-stage carcinogenesis.
    British journal of cancer, 1968, Volume: 22, Issue:1

    Topics: Albumins; Animals; Benz(a)Anthracenes; Carcinogens; Croton Oil; Ear Neoplasms; Exudates and Transuda

1968
[On the carcinogenic properties of o-toluidine and dianisidine].
    Gigiena truda i professional'nye zabolevaniia, 1965, Volume: 9, Issue:7

    Topics: Aniline Compounds; Animals; Biphenyl Compounds; Carcinogens; Mammary Neoplasms, Experimental; Neopla

1965