toluene has been researched along with Disease Models, Animal in 80 studies
methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
Excerpt | Relevance | Reference |
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" The effects of toluene and 1,1,1-trichloroethane (TCE) on NMDA-induced seizures in mice were studied using three experimental protocols: (a) animals injected i." | 7.72 | Effects of inhaled toluene and 1,1,1-trichloroethane on seizures and death produced by N-methyl-D-aspartic acid in mice. ( Balster, RL; Camacho-Muñoz, C; Cruz, SL; Gauthereau, MY; López-Rubalcava, C, 2003) |
" The potential salutary effect of pifithrin alpha, a novel-specific inhibitor of the transcription factor p53, administered 1-6 h following focal reversible cerebral ischemia, was investigated." | 7.72 | The role of p53-induced apoptosis in cerebral ischemia: effects of the p53 inhibitor pifithrin alpha. ( Aharonowiz, M; Greig, NH; Leker, RR; Ovadia, H, 2004) |
"3'-UTR: 3-untranslated region; CIR: cerebral ischemia-reperfusion; CIS: cerebral ischemic stroke; PFT-α: Pifithrin-α; PVDF: polyvinylidene fluoride; SD: Sprague-Dawley; TBST: tris buffered saline with tween." | 3.88 | MiR-125b blocks Bax/Cytochrome C/Caspase-3 apoptotic signaling pathway in rat models of cerebral ischemia-reperfusion injury by targeting p53. ( Jing, L; Xie, YL; Zhang, B, 2018) |
"Volatile organic solvent abuse continues to be a worldwide health problem, including the neurobehavioral teratogenic sequelae of toluene abuse during pregnancy." | 3.85 | Prenatal toluene exposure impairs performance in the Morris Water Maze in adolescent rats. ( Bowen, SE; Callan, SP; Hannigan, JH, 2017) |
" We tested the efficacy of a p53 inhibitor, pifithrin-α p-nitro (PFT) in attenuating steatosis, associated oxidative stress and apoptosis in a murine model of non-alcoholic fatty liver disease (NAFLD)." | 3.79 | Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease. ( Derdak, Z; Harb, R; Sousa, A; Villegas, KA; Wands, JR; Wu, AM, 2013) |
" The effects of toluene and 1,1,1-trichloroethane (TCE) on NMDA-induced seizures in mice were studied using three experimental protocols: (a) animals injected i." | 3.72 | Effects of inhaled toluene and 1,1,1-trichloroethane on seizures and death produced by N-methyl-D-aspartic acid in mice. ( Balster, RL; Camacho-Muñoz, C; Cruz, SL; Gauthereau, MY; López-Rubalcava, C, 2003) |
"The effects of toluene on the sensitivity to seizures induced by aminophylline were investigated." | 3.72 | Toluene exposure increases aminophylline-induced seizure susceptibility in mice. ( Chan, MH; Chen, HH, 2003) |
" The potential salutary effect of pifithrin alpha, a novel-specific inhibitor of the transcription factor p53, administered 1-6 h following focal reversible cerebral ischemia, was investigated." | 3.72 | The role of p53-induced apoptosis in cerebral ischemia: effects of the p53 inhibitor pifithrin alpha. ( Aharonowiz, M; Greig, NH; Leker, RR; Ovadia, H, 2004) |
"A rat model was developed to study toluene-abuse embryopathy, a clinical syndrome which occurs in offspring of women who abuse toluene during pregnancy." | 3.69 | Development of a rat model of toluene-abuse embryopathy. ( Gospe, SM; Saeed, DB; Zeman, FJ; Zhou, SS, 1996) |
" If we use as an exposure measure average lifespan dose estimated with different coefficients of exposure time in an experiment, we get two different dose-response models." | 2.45 | [Quantitative methods of cancer risk assessment in exposure to chemicals]. ( Szymczak, W, 2009) |
"However, once hearing loss is incurred, it is irreversible, and one should be alert to the possible hearing loss induced by toluene and styrene and to the possible additive, potentiating, or synergistic ototoxic effects in case of combined exposure to several chemicals and in case of combined exposure to noise and chemical substances." | 2.44 | Ototoxicity of toluene and styrene: state of current knowledge. ( Hoet, P; Lison, D, 2008) |
"Chronic toluene abuse produces a renal tubular acidosis with maternal hypokalemia and profoundly lowered serum pH." | 2.40 | Teratogen update: toluene. ( Wilkins-Haug, L, 1997) |
" Alternative study approaches to evaluate dose-response relationships are proposed." | 2.40 | 'Multiple chemical sensitivity', the relevance of toxic, neurobiological and psychic effect mechanisms. ( Kiesswetter, E, 1999) |
"Toluene is a widely used organic solvent, heavily employed in many manufacturing industries." | 2.39 | Auditory and vestibular functions after single or combined exposure to toluene: a review. ( Dunn, DE; Johnson, AC; Morata, TC; Nylén, P, 1995) |
"Toluene is a widely used industrial organic solvent and is ubiquitous in our environment." | 1.51 | Acute and Chronic Exposure of Toluene Induces Genotoxicity in Different Regions of the Brain in Normal and Allergic Mouse Models. ( Chen, CC; Laio, TY; Liu, TY; Tsou, HH; Wang, HT, 2019) |
"There are reports of patients whose epileptic seizures are prevented by means of olfactory stimulation." | 1.48 | Intense olfactory stimulation blocks seizures in an experimental model of epilepsy. ( Bertti-Dutra, P; de Lima Umeoka, EH; de Oliveira, JAC; Del Vecchio, F; Delfino-Pereira, P; Fernandes, A; Garcia-Cairasco, N; Marroni, SS; Santos, VR, 2018) |
"Renal ischemia-reperfusion injury is a leading cause of acute kidney injury; the pathogenesis of which remains poorly understood and effective therapies are still lacking." | 1.46 | Induction of microRNA-17-5p by p53 protects against renal ischemia-reperfusion injury by targeting death receptor 6. ( Dong, Z; Hao, J; Li, L; Mei, C; Mei, S; Su, Y; Wei, Q, 2017) |
"Muscular dystrophies are often caused by genetic alterations in the dystrophin-dystroglycan complex or its extracellular ligands." | 1.42 | Immobilization of Dystrophin and Laminin α2-Chain Deficient Zebrafish Larvae In Vivo Prevents the Development of Muscular Dystrophy. ( Arner, A; Li, M, 2015) |
"Unilateral cryptorchidism was surgically induced in the rats of the cryptorchid group, PFT-α group, and cryptorchid+dissolvent of PFT-α group." | 1.40 | [Effect of PFT-α on apoptosis of spermatogenic cells caused by enorchia]. ( He, L; Long, Z; Shi, J; Xie, L; Xie, Y; Yang, Z, 2014) |
" Half dosage of this gene in humans causes most of the features of the DiGeorge or Velocardiofacial syndrome phenotypes, including aortic arch and cardiac outflow tract abnormalities." | 1.40 | p53 Suppression partially rescues the mutant phenotype in mouse models of DiGeorge syndrome. ( Baldini, A; Caprio, C, 2014) |
"The toluene-exposed mice were significantly deficient in the social interaction test, nesting behaviour, social dominance tube test, and novel objective recognition test." | 1.36 | Adolescent toluene exposure produces enduring social and cognitive deficits in mice: an animal model of solvent-induced psychosis. ( Chen, HH; Chung, SS; Lin, BF; Ou, MC; Pang, CY, 2010) |
"Toluene has been shown to inhibit the nicotinic acetylcholine receptors." | 1.35 | Toluene exposure during the brain growth spurt reduced behavioral responses to nicotine in young adult rats: a potential role for nicotinic acetylcholine receptors in fetal solvent syndrome. ( Chan, MH; Chen, HH; Chien, TH; Tang, YC, 2008) |
"The mechanism of cerebral vasospasm following subarachnoid haemorrhage (SAH) is not understood." | 1.35 | Pifithrin-alpha reduces cerebral vasospasm by attenuating apoptosis of endothelial cells in a subarachnoid haemorrhage model of rat. ( Chen, CH; Hu, Q; Luan, LJ; Qin, LH; Shi, XZ; Yan, JH; Yang, L; Yang, XM; Zhao, J; Zhou, CM, 2008) |
"Prion diseases, among them scrapie and BSE, are a group of fatal neurodegenerative disorders associated with the conversion of PrP(C) to PrP(Sc), its conformational abnormal isoform." | 1.33 | Inhibition of P53-related apoptosis had no effect on PrP(Sc) accumulation and prion disease incubation time. ( Engelstein, R; Gabizon, R; Greig, NH; Grigoriadis, N; Ovadia, H, 2005) |
"A physiologically-based pharmacokinetic (PBPK) model for a mixture of toluene (TOL) and xylene (XYL), developed and validated in the rat, was used to predict the uptake and disposition kinetics of TOL/XYL mixture in humans." | 1.29 | Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans. ( Brodeur, J; Charest-Tardif, G; Krishnan, K; Laparé, S; Tardif, R, 1995) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (3.75) | 18.7374 |
1990's | 7 (8.75) | 18.2507 |
2000's | 28 (35.00) | 29.6817 |
2010's | 39 (48.75) | 24.3611 |
2020's | 3 (3.75) | 2.80 |
Authors | Studies |
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Páez-Martínez, N | 1 |
Pellicer, F | 1 |
González-Trujano, ME | 1 |
Cruz-López, B | 1 |
Zhang, L | 3 |
Gao, Y | 3 |
Zhang, R | 1 |
Sun, F | 1 |
Cheng, C | 1 |
Qian, F | 1 |
Duan, X | 1 |
Wei, G | 1 |
Sun, C | 1 |
Pang, X | 1 |
Chen, P | 1 |
Chai, R | 1 |
Yang, T | 4 |
Wu, H | 1 |
Liu, D | 2 |
Nguépy Keubo, FR | 1 |
Mboua, PC | 1 |
Djifack Tadongfack, T | 1 |
Fokouong Tchoffo, E | 1 |
Tasson Tatang, C | 1 |
Ide Zeuna, J | 1 |
Noupoue, EM | 1 |
Tsoplifack, CB | 1 |
Folefack, GO | 1 |
Kettani, M | 1 |
Bandelier, P | 1 |
Huo, J | 1 |
Li, H | 4 |
Yu, D | 1 |
Arulsamy, N | 1 |
AlAbbad, S | 1 |
Sardot, T | 1 |
Lekashvili, O | 1 |
Decato, D | 1 |
Lelj, F | 1 |
Alexander Ross, JB | 1 |
Rosenberg, E | 1 |
Nazir, H | 1 |
Muthuswamy, N | 1 |
Louis, C | 1 |
Jose, S | 1 |
Prakash, J | 1 |
Buan, MEM | 1 |
Flox, C | 1 |
Chavan, S | 1 |
Shi, X | 1 |
Kauranen, P | 1 |
Kallio, T | 1 |
Maia, G | 1 |
Tammeveski, K | 1 |
Lymperopoulos, N | 1 |
Carcadea, E | 1 |
Veziroglu, E | 1 |
Iranzo, A | 1 |
M Kannan, A | 1 |
Arunamata, A | 1 |
Tacy, TA | 1 |
Kache, S | 1 |
Mainwaring, RD | 1 |
Ma, M | 1 |
Maeda, K | 1 |
Punn, R | 1 |
Noguchi, S | 1 |
Hahn, S | 3 |
Iwasa, Y | 3 |
Ling, J | 2 |
Voccio, JP | 2 |
Kim, Y | 3 |
Song, J | 3 |
Bascuñán, J | 2 |
Chu, Y | 1 |
Tomita, M | 1 |
Cazorla, M | 1 |
Herrera, E | 1 |
Palomeque, E | 1 |
Saud, N | 1 |
Hoplock, LB | 1 |
Lobchuk, MM | 1 |
Lemoine, J | 1 |
Li, X | 10 |
Henson, MA | 1 |
Unsihuay, D | 1 |
Qiu, J | 1 |
Swaroop, S | 1 |
Nagornov, KO | 1 |
Kozhinov, AN | 1 |
Tsybin, YO | 1 |
Kuang, S | 1 |
Laskin, J | 1 |
Zin, NNINM | 1 |
Mohamad, MN | 1 |
Roslan, K | 1 |
Abdul Wafi, S | 1 |
Abdul Moin, NI | 1 |
Alias, A | 1 |
Zakaria, Y | 1 |
Abu-Bakar, N | 1 |
Naveed, A | 1 |
Jilani, K | 1 |
Siddique, AB | 1 |
Akbar, M | 1 |
Riaz, M | 1 |
Mushtaq, Z | 1 |
Sikandar, M | 1 |
Ilyas, S | 1 |
Bibi, I | 1 |
Asghar, A | 1 |
Rasool, G | 1 |
Irfan, M | 1 |
Li, XY | 1 |
Zhao, S | 1 |
Fan, XH | 1 |
Chen, KP | 1 |
Hua, W | 1 |
Liu, ZM | 1 |
Xue, XD | 1 |
Zhou, B | 1 |
Zhang, S | 2 |
Xing, YL | 1 |
Chen, MA | 1 |
Sun, Y | 2 |
Neradilek, MB | 1 |
Wu, XT | 1 |
Zhang, D | 2 |
Huang, W | 1 |
Cui, Y | 1 |
Yang, QQ | 1 |
Li, HW | 1 |
Zhao, XQ | 1 |
Hossein Rashidi, B | 1 |
Tarafdari, A | 1 |
Ghazimirsaeed, ST | 1 |
Shahrokh Tehraninezhad, E | 1 |
Keikha, F | 1 |
Eslami, B | 1 |
Ghazimirsaeed, SM | 1 |
Jafarabadi, M | 1 |
Silvani, Y | 1 |
Lovita, AND | 1 |
Maharani, A | 1 |
Wiyasa, IWA | 1 |
Sujuti, H | 1 |
Ratnawati, R | 1 |
Raras, TYM | 1 |
Lemin, AS | 1 |
Rahman, MM | 1 |
Pangarah, CA | 1 |
Kiyu, A | 1 |
Zeng, C | 2 |
Du, H | 1 |
Lin, D | 1 |
Jalan, D | 1 |
Rubagumya, F | 1 |
Hopman, WM | 1 |
Vanderpuye, V | 1 |
Lopes, G | 1 |
Seruga, B | 1 |
Booth, CM | 1 |
Berry, S | 1 |
Hammad, N | 1 |
Sajo, EA | 1 |
Okunade, KS | 1 |
Olorunfemi, G | 1 |
Rabiu, KA | 1 |
Anorlu, RI | 1 |
Xu, C | 2 |
Xiang, Y | 1 |
Xu, X | 1 |
Zhou, L | 3 |
Dong, X | 1 |
Tang, S | 1 |
Gao, XC | 1 |
Wei, CH | 1 |
Zhang, RG | 1 |
Cai, Q | 1 |
He, Y | 1 |
Tong, F | 1 |
Dong, JH | 1 |
Wu, G | 1 |
Dong, XR | 1 |
Tang, X | 1 |
Tao, F | 1 |
Xiang, W | 1 |
Zhao, Y | 2 |
Jin, L | 1 |
Tao, H | 1 |
Lei, Y | 1 |
Gan, H | 1 |
Huang, Y | 1 |
Chen, Y | 3 |
Chen, L | 3 |
Shan, A | 1 |
Zhao, H | 2 |
Wu, M | 2 |
Ma, Q | 1 |
Wang, J | 4 |
Zhang, E | 1 |
Zhang, J | 3 |
Li, Y | 5 |
Xue, F | 1 |
Deng, L | 1 |
Liu, L | 2 |
Yan, Z | 2 |
Wang, Y | 6 |
Meng, J | 1 |
Chen, G | 2 |
Anastassiadou, M | 1 |
Bernasconi, G | 1 |
Brancato, A | 1 |
Carrasco Cabrera, L | 1 |
Greco, L | 1 |
Jarrah, S | 1 |
Kazocina, A | 1 |
Leuschner, R | 1 |
Magrans, JO | 1 |
Miron, I | 1 |
Nave, S | 1 |
Pedersen, R | 1 |
Reich, H | 1 |
Rojas, A | 1 |
Sacchi, A | 1 |
Santos, M | 1 |
Theobald, A | 1 |
Vagenende, B | 1 |
Verani, A | 1 |
Du, L | 1 |
Liu, X | 1 |
Ren, Y | 1 |
Li, J | 8 |
Li, P | 1 |
Jiao, Q | 1 |
Meng, P | 1 |
Wang, F | 3 |
Wang, YS | 1 |
Wang, C | 3 |
Zhou, X | 2 |
Wang, W | 1 |
Wang, S | 2 |
Hou, J | 1 |
Zhang, A | 1 |
Lv, B | 1 |
Gao, C | 1 |
Pang, D | 1 |
Lu, K | 1 |
Ahmad, NH | 1 |
Wang, L | 1 |
Zhu, J | 2 |
Zhuang, T | 1 |
Tu, J | 1 |
Zhao, Z | 1 |
Qu, Y | 1 |
Yao, H | 1 |
Wang, X | 7 |
Lee, DF | 1 |
Shen, J | 3 |
Wen, L | 1 |
Huang, G | 2 |
Xie, X | 1 |
Zhao, Q | 1 |
Hu, W | 1 |
Zhang, Y | 4 |
Wu, X | 1 |
Lu, J | 2 |
Li, M | 2 |
Li, W | 2 |
Wu, W | 1 |
Du, F | 1 |
Ji, H | 1 |
Yang, X | 2 |
Xu, Z | 1 |
Wan, L | 1 |
Wen, Q | 1 |
Cho, CH | 1 |
Zou, C | 1 |
Xiao, Z | 1 |
Liao, J | 1 |
Su, X | 1 |
Bi, Z | 1 |
Su, Q | 1 |
Huang, H | 1 |
Wei, Y | 2 |
Na, KJ | 1 |
Choi, H | 1 |
Oh, HR | 1 |
Kim, YH | 1 |
Lee, SB | 1 |
Jung, YJ | 1 |
Koh, J | 1 |
Park, S | 1 |
Lee, HJ | 1 |
Jeon, YK | 1 |
Chung, DH | 1 |
Paeng, JC | 1 |
Park, IK | 1 |
Kang, CH | 1 |
Cheon, GJ | 1 |
Kang, KW | 1 |
Lee, DS | 1 |
Kim, YT | 1 |
Pajuelo-Lozano, N | 1 |
Alcalá, S | 1 |
Sainz, B | 1 |
Perona, R | 1 |
Sanchez-Perez, I | 1 |
Logotheti, S | 1 |
Marquardt, S | 1 |
Gupta, SK | 1 |
Richter, C | 1 |
Edelhäuser, BAH | 1 |
Engelmann, D | 1 |
Brenmoehl, J | 1 |
Söhnchen, C | 1 |
Murr, N | 1 |
Alpers, M | 1 |
Singh, KP | 1 |
Wolkenhauer, O | 1 |
Heckl, D | 1 |
Spitschak, A | 1 |
Pützer, BM | 1 |
Liao, Y | 1 |
Cheng, J | 1 |
Kong, X | 1 |
Li, S | 1 |
Zhang, M | 4 |
Zhang, H | 3 |
Dong, Y | 1 |
Xu, Y | 1 |
Yuan, Z | 1 |
Cao, J | 1 |
Zheng, Y | 1 |
Luo, Z | 1 |
Mei, Z | 1 |
Yao, Y | 1 |
Liu, Z | 2 |
Liang, C | 1 |
Yang, H | 1 |
Song, Y | 1 |
Yu, K | 1 |
Zhu, C | 1 |
Huang, Z | 1 |
Qian, J | 1 |
Ge, J | 1 |
Hu, J | 2 |
Wang, H | 2 |
Liu, Y | 4 |
Mi, Y | 1 |
Kong, H | 1 |
Xi, D | 1 |
Yan, W | 1 |
Luo, X | 1 |
Ning, Q | 1 |
Chang, X | 2 |
Zhang, T | 2 |
Wang, Q | 2 |
Rathore, MG | 1 |
Reddy, K | 1 |
Chen, H | 1 |
Shin, SH | 1 |
Ma, WY | 1 |
Bode, AM | 1 |
Dong, Z | 3 |
Mu, W | 1 |
Liu, C | 3 |
Gao, F | 1 |
Qi, Y | 1 |
Lu, H | 1 |
Zhang, X | 5 |
Cai, X | 1 |
Ji, RY | 1 |
Hou, Y | 3 |
Tian, J | 2 |
Shi, Y | 1 |
Ying, S | 1 |
Tan, M | 1 |
Feng, G | 1 |
Kuang, Y | 1 |
Chen, D | 1 |
Wu, D | 3 |
Zhu, ZQ | 1 |
Tang, HX | 1 |
Shi, ZE | 1 |
Kang, J | 1 |
Liu, Q | 2 |
Qi, J | 3 |
Mu, J | 1 |
Cong, Z | 1 |
Chen, S | 2 |
Fu, D | 1 |
Li, Z | 2 |
Celestrin, CP | 1 |
Rocha, GZ | 1 |
Stein, AM | 1 |
Guadagnini, D | 1 |
Tadelle, RM | 1 |
Saad, MJA | 1 |
Oliveira, AG | 1 |
Bianconi, V | 1 |
Bronzo, P | 1 |
Banach, M | 1 |
Sahebkar, A | 1 |
Mannarino, MR | 1 |
Pirro, M | 1 |
Patsourakos, NG | 1 |
Kouvari, M | 1 |
Kotidis, A | 1 |
Kalantzi, KI | 1 |
Tsoumani, ME | 1 |
Anastasiadis, F | 1 |
Andronikos, P | 1 |
Aslanidou, T | 1 |
Efraimidis, P | 1 |
Georgiopoulos, A | 1 |
Gerakiou, K | 1 |
Grigoriadou-Skouta, E | 1 |
Grigoropoulos, P | 1 |
Hatzopoulos, D | 1 |
Kartalis, A | 1 |
Lyras, A | 1 |
Markatos, G | 1 |
Mikrogeorgiou, A | 1 |
Myroforou, I | 1 |
Orkopoulos, A | 1 |
Pavlidis, P | 1 |
Petras, C | 1 |
Riga, M | 1 |
Skouloudi, M | 1 |
Smyrnioudis, N | 1 |
Thomaidis, K | 1 |
Tsikouri, GE | 1 |
Tsikouris, EI | 1 |
Zisimos, K | 1 |
Vavoulis, P | 1 |
Vitali, MG | 1 |
Vitsas, G | 1 |
Vogiatzidis, C | 1 |
Chantanis, S | 1 |
Fousas, S | 1 |
Panagiotakos, DB | 1 |
Tselepis, AD | 1 |
Jungen, C | 1 |
Alken, FA | 1 |
Eickholt, C | 1 |
Scherschel, K | 1 |
Kuklik, P | 1 |
Klatt, N | 1 |
Schwarzl, J | 1 |
Moser, J | 1 |
Jularic, M | 1 |
Akbulak, RO | 1 |
Schaeffer, B | 1 |
Willems, S | 1 |
Meyer, C | 1 |
Nowak, JK | 1 |
Szczepanik, M | 1 |
Trypuć, M | 1 |
Pogorzelski, A | 1 |
Bobkowski, W | 1 |
Grytczuk, M | 1 |
Minarowska, A | 1 |
Wójciak, R | 1 |
Walkowiak, J | 1 |
Lu, Y | 1 |
Xi, J | 1 |
Li, C | 2 |
Chen, W | 2 |
Hu, X | 1 |
Zhang, F | 1 |
Wei, H | 1 |
Wang, Z | 1 |
Gurzu, S | 1 |
Jung, I | 1 |
Sugimura, H | 2 |
Stefan-van Staden, RI | 1 |
Yamada, H | 1 |
Natsume, H | 1 |
Iwashita, Y | 1 |
Szodorai, R | 1 |
Szederjesi, J | 1 |
Yari, D | 1 |
Ehsanbakhsh, Z | 1 |
Validad, MH | 1 |
Langroudi, FH | 1 |
Esfandiari, H | 1 |
Prager, A | 1 |
Hassanpour, K | 1 |
Kurup, SP | 1 |
Mets-Halgrimson, R | 1 |
Yoon, H | 1 |
Zeid, JL | 1 |
Mets, MB | 1 |
Rahmani, B | 1 |
Araujo-Castillo, RV | 1 |
Culquichicón, C | 1 |
Solis Condor, R | 1 |
Efendi, F | 1 |
Sebayang, SK | 1 |
Astutik, E | 1 |
Hadisuyatmana, S | 1 |
Has, EMM | 1 |
Kuswanto, H | 1 |
Foroutan, T | 1 |
Ahmadi, F | 1 |
Moayer, F | 1 |
Khalvati, S | 1 |
Zhang, Q | 2 |
Lyu, Y | 1 |
Huang, J | 1 |
Yu, N | 1 |
Wen, Z | 1 |
Hou, H | 1 |
Zhao, T | 1 |
Gupta, A | 1 |
Khosla, N | 1 |
Govindasamy, V | 1 |
Saini, A | 1 |
Annapurna, K | 1 |
Dhakate, SR | 1 |
Akkaya, Ö | 1 |
Chandgude, AL | 1 |
Dömling, A | 1 |
Harnett, J | 1 |
Oakes, K | 1 |
Carè, J | 1 |
Leach, M | 1 |
Brown, D | 1 |
Cramer, H | 1 |
Pinder, TA | 1 |
Steel, A | 1 |
Anheyer, D | 1 |
Cantu, J | 1 |
Valle, J | 1 |
Flores, K | 1 |
Gonzalez, D | 1 |
Valdes, C | 1 |
Lopez, J | 1 |
Padilla, V | 1 |
Alcoutlabi, M | 1 |
Parsons, J | 1 |
Núñez, K | 1 |
Hamed, M | 1 |
Fort, D | 1 |
Bruce, D | 1 |
Thevenot, P | 1 |
Cohen, A | 1 |
Weber, P | 1 |
Menezes, AMB | 1 |
Gonçalves, H | 1 |
Perez-Padilla, R | 1 |
Jarvis, D | 1 |
de Oliveira, PD | 1 |
Wehrmeister, FC | 1 |
Mir, S | 1 |
Wong, J | 1 |
Ryan, CM | 1 |
Bellingham, G | 1 |
Singh, M | 2 |
Waseem, R | 1 |
Eckert, DJ | 1 |
Chung, F | 1 |
Hegde, H | 1 |
Shimpi, N | 1 |
Panny, A | 1 |
Glurich, I | 1 |
Christie, P | 1 |
Acharya, A | 1 |
English, KL | 1 |
Downs, M | 1 |
Goetchius, E | 1 |
Buxton, R | 1 |
Ryder, JW | 1 |
Ploutz-Snyder, R | 1 |
Guilliams, M | 1 |
Scott, JM | 1 |
Ploutz-Snyder, LL | 1 |
Martens, C | 1 |
Goplen, FK | 1 |
Aasen, T | 1 |
Gjestad, R | 1 |
Nordfalk, KF | 1 |
Nordahl, SHG | 1 |
Inoue, T | 1 |
Soshi, S | 1 |
Kubota, M | 1 |
Marumo, K | 1 |
Mortensen, NP | 1 |
Caffaro, MM | 1 |
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Cai, L | 1 |
Commodore, L | 1 |
Xu, Q | 1 |
Keats, J | 1 |
Wardwell, S | 1 |
Ning, Y | 1 |
Snodgrass, JT | 1 |
Broudy, MI | 1 |
Russian, K | 1 |
Iuliucci, J | 1 |
Rivera, VM | 1 |
Sawyer, TK | 1 |
Dalgarno, DC | 1 |
Clackson, T | 1 |
Shakespeare, WC | 1 |
Yoshida, Y | 1 |
Gmaz, JM | 1 |
Matthews, BA | 1 |
McKay, BE | 1 |
Xu, H | 1 |
Menendez, S | 1 |
Schlegelberger, B | 1 |
Bae, N | 1 |
Aplan, PD | 1 |
Göhring, G | 1 |
Deblasio, TR | 1 |
Nimer, SD | 1 |
Leeper, NJ | 1 |
Raiesdana, A | 1 |
Kojima, Y | 1 |
Kundu, RK | 1 |
Cheng, H | 1 |
Maegdefessel, L | 1 |
Toh, R | 1 |
Ahn, GO | 1 |
Ali, ZA | 1 |
Anderson, DR | 1 |
Miller, CL | 1 |
Roberts, SC | 1 |
Spin, JM | 1 |
de Almeida, PE | 1 |
Wu, JC | 1 |
Xu, B | 1 |
Cheng, K | 1 |
Quertermous, M | 1 |
Kundu, S | 1 |
Kortekaas, KE | 1 |
Berzin, E | 1 |
Downing, KP | 1 |
Dalman, RL | 1 |
Tsao, PS | 1 |
Schadt, EE | 1 |
Owens, GK | 1 |
Quertermous, T | 1 |
Derdak, Z | 1 |
Villegas, KA | 1 |
Harb, R | 1 |
Wu, AM | 1 |
Sousa, A | 1 |
Wands, JR | 1 |
Sutton, TA | 1 |
Hato, T | 1 |
Mai, E | 1 |
Yoshimoto, M | 1 |
Kuehl, S | 1 |
Anderson, M | 1 |
Mang, H | 1 |
Plotkin, Z | 1 |
Chan, RJ | 1 |
Dagher, PC | 1 |
Cruz, SL | 1 |
Gauthereau, MY | 1 |
Camacho-Muñoz, C | 1 |
López-Rubalcava, C | 1 |
Balster, RL | 1 |
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Skowronski, GA | 1 |
Suh, DH | 1 |
Abdel-Rahman, MS | 1 |
Bäumer, W | 1 |
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Hoppmann, J | 1 |
Ehinger, AM | 1 |
Rundfeldt, C | 1 |
Kietzmann, M | 1 |
Chan, MH | 2 |
Sills, RC | 1 |
Hong, HL | 1 |
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Moomaw, C | 1 |
Clayton, N | 1 |
Boorman, GA | 1 |
Dunnick, J | 1 |
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Filley, CM | 1 |
Halliday, W | 1 |
Kleinschmidt-DeMasters, BK | 1 |
Leker, RR | 1 |
Aharonowiz, M | 1 |
Ovadia, H | 2 |
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Grigoriadis, N | 1 |
Gabizon, R | 1 |
Zhou, C | 1 |
Yamaguchi, M | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Evaluation of New Neuroinflammation Markers in Subarachnoid Haemorrhage Patients: a Pilot Study[NCT03411746] | 60 participants (Actual) | Observational | 2018-01-26 | Completed | |||
An Open Randomized Comparative Trial of Four Different Dressings for Cutaneous Coverage in Pemphigus and Pemphigoid[NCT02365675] | 12 participants (Anticipated) | Interventional | 2015-01-31 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
9 reviews available for toluene and Disease Models, Animal
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
[Quantitative methods of cancer risk assessment in exposure to chemicals].
Topics: Algorithms; Animals; Benchmarking; Carcinogens; Disease Models, Animal; Dose-Response Relationship, | 2009 |
Neurotoxicity of toluene.
Topics: Animals; Brain; Disease Models, Animal; Environmental Pollutants; Humans; Mice; Neuroimmunomodulatio | 2010 |
The effects of toluene on the central nervous system.
Topics: Administration, Inhalation; Adult; Animals; Central Nervous System; Child; Disease Models, Animal; F | 2004 |
Ototoxicity of toluene and styrene: state of current knowledge.
Topics: Animals; Disease Models, Animal; Hearing Loss; Humans; Occupational Exposure; Solvents; Styrene; Tol | 2008 |
Auditory and vestibular functions after single or combined exposure to toluene: a review.
Topics: Animals; Cochlea; Disease Models, Animal; Hearing; Humans; Occupational Exposure; Solvents; Toluene; | 1995 |
Teratogen update: toluene.
Topics: Abnormalities, Drug-Induced; Acidosis, Renal Tubular; Administration, Inhalation; Administration, Or | 1997 |
'Multiple chemical sensitivity', the relevance of toxic, neurobiological and psychic effect mechanisms.
Topics: Animals; Disease Models, Animal; Environmental Pollutants; Humans; Multiple Chemical Sensitivity; To | 1999 |
5-Chloro-ortho-toluidine.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Coloring Agents; Disease Models, Animal; Environmental | 2000 |
1 trial available for toluene and Disease Models, Animal
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
71 other studies available for toluene and Disease Models, Animal
Article | Year |
---|---|
Environmental enrichment reduces behavioural sensitization in mice previously exposed to toluene: The role of D1 receptors.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Caudate Nucleus; Central Nervous System Sensitizatio | 2020 |
THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis.
Topics: Animals; Apoptosis; Benzothiazoles; CRISPR-Associated Protein 9; Deafness; Disease Models, Animal; D | 2020 |
Dopaminergic Neuron-Specific Deletion of p53 Gene Attenuates Methamphetamine Neurotoxicity.
Topics: Animals; bcl-2-Associated X Protein; Benzothiazoles; Central Nervous System Stimulants; Disease Mode | 2017 |
Bre Enhances Osteoblastic Differentiation by Promoting the Mdm2-Mediated Degradation of p53.
Topics: Animals; Benzothiazoles; Bone and Bones; Bone Marrow Cells; Cell Differentiation; Cyclin-Dependent K | 2017 |
Toluene exposure enhances acute and chronic formalin-induced nociception in rats: Participation of 5-HT
Topics: Animals; Disease Models, Animal; Disinfectants; Dose-Response Relationship, Drug; Female; Formaldehy | 2017 |
A novel mouse model of atopic dermatitis that is T helper 2 (Th2)-polarized by an epicutaneous allergen.
Topics: Allergens; Animals; Dermatitis, Atopic; Detergents; Dinitrochlorobenzene; Disease Models, Animal; Fe | 2018 |
Intense olfactory stimulation blocks seizures in an experimental model of epilepsy.
Topics: Acoustic Stimulation; Amygdala; Animals; Brain Stem; Disease Models, Animal; Epilepsy, Reflex; Kindl | 2018 |
Neuroprotective effects of pifithrin-α against traumatic brain injury in the striatum through suppression of neuroinflammation, oxidative stress, autophagy, and apoptosis.
Topics: Animals; Apoptosis; Autophagy; Benzothiazoles; Blotting, Western; Brain Injuries, Traumatic; Disease | 2018 |
Does p53 Inhibition Suppress Myocardial Ischemia-Reperfusion Injury?
Topics: Animals; Benzothiazoles; Disease Models, Animal; Male; Mice, Inbred C57BL; Mice, Knockout; Myocardia | 2018 |
MiR-125b blocks Bax/Cytochrome C/Caspase-3 apoptotic signaling pathway in rat models of cerebral ischemia-reperfusion injury by targeting p53.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; Brain Infarction; Brain Ischemia; Ca | 2018 |
Tumor suppressor protein p53 negatively regulates ischemia-induced angiogenesis and arteriogenesis.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Benzothiazoles; Blood Flow Velocity; | 2018 |
Adolescent Inhalant Abuse Results in Adrenal Dysfunction and a Hypermetabolic Phenotype with Persistent Growth Impairments.
Topics: Adolescent; Adolescent Behavior; Adolescent Development; Adrenal Gland Diseases; Adrenal Glands; Ani | 2018 |
The atopic dermatitis-like lesion and the associated MRSA infection and barrier dysfunction can be alleviated by 2,4-dimethoxy-6-methylbenzene-1,3-diol from Antrodia camphorata.
Topics: Administration, Cutaneous; Animals; Anti-Bacterial Agents; Antrodia; Cell Line; Chemokines; Dermatit | 2018 |
Novel Role of p53 in Septic Immunosuppression: Involvement in Loss and Dysfunction of CD4+ T Lymphocytes.
Topics: Animals; Apoptosis; Benzothiazoles; CD4-Positive T-Lymphocytes; Disease Models, Animal; Humans; Jurk | 2018 |
In Vitro and in Vivo Effect of MAPK Signal Transduction Pathway Inhibitors on Echinococcus multilocularis.
Topics: Albendazole; Animals; Anthelmintics; Benzamides; Body Weight; Cell Line; Disease Models, Animal; Ech | 2019 |
Acute and Chronic Exposure of Toluene Induces Genotoxicity in Different Regions of the Brain in Normal and Allergic Mouse Models.
Topics: Animals; Brain; Comet Assay; Disease Models, Animal; DNA Damage; Hypersensitivity; Male; Mice, Inbre | 2019 |
p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin.
Topics: Animals; Benzothiazoles; Caspase 6; Cells, Cultured; Disease Models, Animal; Female; Fibroblasts; Hu | 2014 |
[Effect of PFT-α on apoptosis of spermatogenic cells caused by enorchia].
Topics: Animals; Apoptosis; Benzothiazoles; Cryptorchidism; Disease Models, Animal; Humans; Male; Rats; Rats | 2014 |
[Neurotoxic effect of toluene on background of prenatal hypoxic brain damage to white rats].
Topics: Animals; Behavior, Animal; Brain; Cognition Disorders; Disease Models, Animal; Electroencephalograph | 2014 |
p53 Suppression partially rescues the mutant phenotype in mouse models of DiGeorge syndrome.
Topics: Animals; Arteries; Benzothiazoles; Branchial Region; Chromatin; Crosses, Genetic; DiGeorge Syndrome; | 2014 |
Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury.
Topics: Animals; Apoptosis; Benzothiazoles; Brain Injuries; Cell Survival; Disease Models, Animal; Male; Neu | 2015 |
Prenatal toluene exposure impairs performance in the Morris Water Maze in adolescent rats.
Topics: Animals; Disease Models, Animal; Female; Male; Maze Learning; Pregnancy; Prenatal Exposure Delayed E | 2017 |
Immobilization of Dystrophin and Laminin α2-Chain Deficient Zebrafish Larvae In Vivo Prevents the Development of Muscular Dystrophy.
Topics: Animals; Birefringence; Disease Models, Animal; Dystrophin; Laminin; Larva; Muscle Contraction; Musc | 2015 |
Regenerative repair of Pifithrin-α in cerebral ischemia via VEGF dependent manner.
Topics: Animals; Benzothiazoles; Brain Ischemia; Cell Proliferation; Disease Models, Animal; In Vitro Techni | 2016 |
Cardiac arrest triggers hippocampal neuronal death through autophagic and apoptotic pathways.
Topics: Animals; Apoptosis; Autophagy; Benzothiazoles; Biomarkers; Blood Gas Analysis; Cell Death; Disease M | 2016 |
Post-traumatic administration of the p53 inactivator pifithrin-α oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury.
Topics: Aldehydes; Animals; Annexin A5; Apoptosis Regulatory Proteins; Benzothiazoles; Brain; Brain Injuries | 2016 |
Induction of microRNA-17-5p by p53 protects against renal ischemia-reperfusion injury by targeting death receptor 6.
Topics: Acute Kidney Injury; Animals; Apoptosis; Benzothiazoles; Caspases; Cell Line; Disease Models, Animal | 2017 |
Inhibition of p53 transcriptional activity: a potential target for future development of therapeutic strategies for primary demyelination.
Topics: Animals; Benzothiazoles; Cells, Cultured; Cuprizone; Demyelinating Diseases; Disease Models, Animal; | 2008 |
Selective activation of p38 mitogen-activated protein kinase in dopaminergic neurons of substantia nigra leads to nuclear translocation of p53 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Benzothiazoles; Brain; | 2008 |
Strain differences in extracellular amino acid neurotransmitter levels in the hippocampi of major histocompatibility complex congenic mice in response to toluene exposure.
Topics: Amino Acids; Animals; Disease Models, Animal; Extracellular Fluid; Glycine; Haplotypes; Hippocampus; | 2009 |
Characterization of an inhaled toluene drug discrimination in mice: effect of exposure conditions and route of administration.
Topics: Animals; Central Nervous System; Discrimination, Psychological; Disease Models, Animal; Humans; Illi | 2009 |
Delayed treatment with a p53 inhibitor enhances recovery in stroke brain.
Topics: Adult Stem Cells; Analysis of Variance; Animals; Benzothiazoles; Brain; Bromodeoxyuridine; Cell Diff | 2009 |
Thinner inhalation effects on oxidative stress and DNA repair in a rat model of abuse.
Topics: Animals; Biomarkers; Body Weight; Bone Marrow; Disease Models, Animal; DNA Damage; DNA Repair; Inhal | 2010 |
Activation of p53 promotes renal injury in acute aristolochic acid nephropathy.
Topics: Animals; Apoptosis; Aristolochic Acids; Benzothiazoles; Cells, Cultured; Disease Models, Animal; Dos | 2010 |
Can T-cell deficiency affect spatial learning ability following toluene exposure?
Topics: Animals; Astrocytes; Disease Models, Animal; Immune Tolerance; Immunity, Cellular; Immunity, Innate; | 2010 |
Adolescent toluene exposure produces enduring social and cognitive deficits in mice: an animal model of solvent-induced psychosis.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cognition Disorders; Corn Oil; Di | 2010 |
Strain differences influence N-methyl-D-aspartate receptor subunit gene expression in the olfactory bulb of an allergic mouse model following toluene exposure.
Topics: Allergens; Animals; Disease Models, Animal; Gene Expression Regulation; Hypersensitivity; Male; Mice | 2010 |
Synthesis and biological evaluation of imidazolo[2,1-b]benzothiazole derivatives, as potential p53 inhibitors.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Disease Models, Animal; Female; Ge | 2011 |
Discovery of 5-(arenethynyl) hetero-monocyclic derivatives as potent inhibitors of BCR-ABL including the T315I gatekeeper mutant.
Topics: Administration, Oral; Alkynes; Aniline Compounds; Animals; Cyclization; Disease Models, Animal; Fusi | 2011 |
Dysregulation of immune responses in an allergic mouse model following low-level toluene exposure.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Gen | 2011 |
Toluene inhalation modulates dentate gyrus granule cell output in vivo.
Topics: Administration, Inhalation; Animals; Cognition Disorders; Dentate Gyrus; Disease Models, Animal; Fem | 2012 |
Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model.
Topics: Animals; Benzothiazoles; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Flow Cytom | 2012 |
Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
Topics: Adolescent; Adult; Aged; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Benzothia | 2013 |
Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Apoptosis; Benzothiazoles; Cell Line; Diet, High-Fat; Disease Models, | 2013 |
p53 is renoprotective after ischemic kidney injury by reducing inflammation.
Topics: Acute Kidney Injury; Animals; Apoptosis; Benzothiazoles; Bone Marrow Transplantation; Chimera; Cytok | 2013 |
Effects of inhaled toluene and 1,1,1-trichloroethane on seizures and death produced by N-methyl-D-aspartic acid in mice.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; | 2003 |
Effect of a chemical mixture on dermal penetration of arsenic and nickel in male pig in vitro.
Topics: Animals; Arsenic Poisoning; Arsenicals; Chloroform; Disease Models, Animal; Drug Synergism; Hazardou | 2003 |
AWD 12-281, a highly selective phosphodiesterase 4 inhibitor, is effective in the prevention and treatment of inflammatory reactions in a model of allergic dermatitis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Administration, Topical; Amides; Animals; | 2003 |
Toluene exposure increases aminophylline-induced seizure susceptibility in mice.
Topics: Aminophylline; Animals; Benzaldehydes; Bronchodilator Agents; Caffeine; Disease Models, Animal; Drug | 2003 |
o-Nitrotoluene-induced large intestinal tumors in B6C3F1 mice model human colon cancer in their molecular pathogenesis.
Topics: Animals; Base Sequence; beta Catenin; Carcinogens; Cecal Neoplasms; Codon; Colonic Neoplasms; Cytosk | 2004 |
The role of p53-induced apoptosis in cerebral ischemia: effects of the p53 inhibitor pifithrin alpha.
Topics: Animals; Apoptosis; Benzothiazoles; Blotting, Western; Brain; Brain Ischemia; Cell Count; Disability | 2004 |
Inhibition of P53-related apoptosis had no effect on PrP(Sc) accumulation and prion disease incubation time.
Topics: Animals; Apoptosis; Benzothiazoles; Brain; Caspase 3; Caspases; Cell Line; Cricetinae; Disease Model | 2005 |
Role of p53 and apoptosis in cerebral vasospasm after experimental subarachnoid hemorrhage.
Topics: Animals; Apoptosis; Basilar Artery; Benzothiazoles; Blotting, Western; Brain; Cerebral Angiography; | 2005 |
Effects of p53 inhibitor on survival and death of cells subjected to oxidative stress.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Benzothiazoles; Brain Ischemia; Cell Death; Cell Shape; C | 2005 |
Metabolic correlates of toluene abuse: decline and recovery of function in adolescent animals.
Topics: Animals; Brain; Brain Mapping; Disease Models, Animal; Fluorodeoxyglucose F18; Inhalation Exposure; | 2006 |
[On probable use of general vibration as a functional load in studies of xylene and toluene exposure].
Topics: Animals; Disease Models, Animal; Electrocardiography; Environmental Exposure; Environmental Illness; | 2006 |
Transcription factor p53 in degenerating spinal cords.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Behavior, Animal; Benzothiazoles; Case-Control | 2007 |
Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kappaB transcriptional activity.
Topics: Animals; Apoptosis; Benzothiazoles; Brain Injuries; Disease Models, Animal; Female; Humans; Male; Mi | 2007 |
Activation and involvement of p53 in cisplatin-induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Apoptosis; Benzothiazoles; Cisplatin; Disease M | 2007 |
Toluene exposure during the brain growth spurt reduced behavioral responses to nicotine in young adult rats: a potential role for nicotinic acetylcholine receptors in fetal solvent syndrome.
Topics: Aging; Animals; Behavior, Animal; Blotting, Western; Body Temperature; Brain; Disease Models, Animal | 2008 |
Evaluation of the cough reflex and airway reactivity in toluene- and ovalbumin-induced airway hyperresponsiveness.
Topics: Airway Resistance; Animals; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Age | 2007 |
Pifithrin-alpha reduces cerebral vasospasm by attenuating apoptosis of endothelial cells in a subarachnoid haemorrhage model of rat.
Topics: Animals; Apoptosis; Benzothiazoles; Blotting, Western; Disease Models, Animal; Endothelial Cells; Ma | 2008 |
Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans.
Topics: Animals; Body Weight; Computer Simulation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; | 1995 |
Development of a rat model of toluene-abuse embryopathy.
Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Brain; Disease Models, Animal; Eating; F | 1996 |
Irritant reactions on hairless micropig skin: a model for testing barrier creams?
Topics: Alopecia; Animals; Body Water; Dermatitis, Irritant; Disease Models, Animal; Drug Evaluation, Precli | 1995 |
Effect of toluene inhalation on astrocytes and neurotrophic factor in rat brain.
Topics: Acute Disease; Animals; Astrocytes; Brain; Brain Chemistry; Chronic Disease; Disease Models, Animal; | 2000 |
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.
Topics: Amyloid beta-Peptides; Animals; Antineoplastic Agents; Benzothiazoles; Brain Ischemia; Caspase 3; Ca | 2001 |
Neurobehavioral development of rats exposed to toluene through maternal milk.
Topics: Animals; Brain; Disease Models, Animal; Female; Milk; Pregnancy; Rats; Rats, Wistar; Toluene | 1991 |
Lung bacterial clearance in the burned rat.
Topics: Animals; Burns; Disease Models, Animal; Lung; Male; Ointments; Pseudomonas aeruginosa; Pseudomonas I | 1970 |
Burn wound dressings. I. Effect on insensible water loss.
Topics: Acetates; Animals; Bandages; Burns; Dehydration; Disease Models, Animal; Ointments; Petrolatum; Rats | 1971 |
Burn wound dressings. II. Effect on wound sepsis.
Topics: Acetates; Animals; Bandages; Burns; Disease Models, Animal; Nitrofurazone; Ointments; Petrolatum; Ra | 1971 |