toluene has been researched along with Body Weight in 94 studies
methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These studies explored the effects of brief, repeated, prenatal toluene exposures in pregnant female rats on body weight, metabolic rate, body composition, and food intake in their offspring." | 3.74 | Effects of abuse pattern of gestational toluene exposure on metabolism, feeding and body composition. ( Bowen, SE; Coscina, DV; Fata, E; Jarosz, PA; Jen, KL, 2008) |
| "The present study was undertaken in order to investigate if toluene induced oxidative stress in brains from rats exposed prenatally to 1800 ppm toluene 6 hr/day at days 7-20 during the pregnancy." | 3.71 | Changes in markers of oxidative stress and membrane properties in synaptosomes from rats exposed prenatally to toluene. ( Edelfors, S; Hass, U; Hougaard, KS, 2002) |
| " Individual measurements of age, ventilation rate, blood/air partition coefficient, body weight, and adipose tissue fraction were made on 26 male subjects exposed to 50 ppm 2H8-toluene and 50 ppm toluene for 2 hr at rest, with collection of venous blood samples for 120 hr postexposure." | 3.69 | Interindividual differences in 2H8-toluene toxicokinetics assessed by semiempirical physiologically based model. ( Dills, RL; Kalman, DA; Morgan, MS; Nothstein, GL; Pierce, CH; Shen, DD, 1996) |
| "Toluene exposure was negatively associated with body weight ( d = -0." | 2.61 | Growth changes after inhalant abuse and toluene exposure: A systematic review and meta-analysis of human and animal studies. ( Andrews, ZB; Churilov, L; Crossin, R; Duncan, JR; Lawrence, AJ, 2019) |
| "Inhalant abuse is prevalent in adolescent populations, with chronic use resulting in neurobiological and cognitive abnormalities in adulthood." | 1.40 | Specific impairments in instrumental learning following chronic intermittent toluene inhalation in adolescent rats. ( Axelsson, M; Dick, AL; Duncan, JR; Lawrence, AJ, 2014) |
| "Benzene is an important industrial chemical." | 1.35 | Genotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice. ( Allison, N; Bird, MG; Dorman, DC; Gao, P; Letinski, DJ; Nicolich, MJ; Roberts, KC; Sharma, S; Struve, MF; Wetmore, BA, 2008) |
| " At Caesarean section on GD20, no adverse effects on implantation, number and viability of fetuses, or fetal sex distribution were observed." | 1.34 | Developmental and reproductive toxicity evaluation of toluene vapor in the rat II. Developmental toxicity. ( Nicolich, MJ; Roberts, LG; Schreiner, CA, 2007) |
| " Another group of "conditioned-sedentary" (C-S) rats was dosed similarly but did not perform the LPT." | 1.34 | The role of physical activity and feeding schedule on the kinetics of inhaled and oral toluene in rats. ( Bushnell, PJ; Klinger, R; Oshiro, WM; Samsam, TE, 2007) |
| "Body weight was significantly decreased in the toluene group (P < 0." | 1.33 | Immunohistochemical study of rat spermatogenesis after toluene-inhalation. ( Gotohda, T; Ishigami, A; Kubo, S; Tokunaga, I, 2005) |
| "Toluene has been reported to antagonize the function of N-methyl-D-aspartate (NMDA) receptors." | 1.33 | Neonatal toluene exposure alters agonist and antagonist sensitivity and NR2B subunit expression of NMDA receptors in cultured cerebellar granule neurons. ( Chan, MH; Chen, HH; Chien, TH; Lin, YR; Wei, CT, 2005) |
| " The methodology involved the use of a previously validated physiologically based pharmacokinetic (PBPK) model, in which the intrinsic clearance for hepatic metabolism (CL(int)) was expressed in terms of the CYP2E1 content." | 1.33 | Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene. ( Hines, RN; Krishnan, K; McCarver, DG; Nong, A, 2006) |
| "Modeling of pharmacokinetic parameters and pharmacodynamic actions requires knowledge of the arterial blood concentration." | 1.32 | Physiologically based pharmacokinetic modeling of arterial - antecubital vein concentration difference. ( Levitt, DG, 2004) |
| "Toluene is a major component of numerous commercial organic solvent formulations." | 1.31 | Assessment of long-term effects of exposure to toluene based on the analysis of selected behavioral responses with particular reference to the ability to trigger behavioral hypersensitivity in rats. ( Tomas, T; Wiaderna, D, 2002) |
| "A physiologically-based pharmacokinetic (PBPK) model for a mixture of toluene (TOL) and xylene (XYL), developed and validated in the rat, was used to predict the uptake and disposition kinetics of TOL/XYL mixture in humans." | 1.29 | Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans. ( Brodeur, J; Charest-Tardif, G; Krishnan, K; Laparé, S; Tardif, R, 1995) |
| "Chloroform treatment did not affect the activity of N-nitrosodimethylamine N-demethylase in pretreated rats; the high dose increased the activity in control rats." | 1.29 | Different contributions of cytochrome P450 2E1 and P450 2B1/2 to chloroform hepatotoxicity in rat. ( Aoyama, T; Elovaara, E; Gelboin, HV; Klockars, M; Nakajima, T; Okino, T; Riihimäki, V; Vainio, H, 1995) |
| " With both vehicles CTFT and alpha 2u-globulin were found to accumulate in the male rat kidney after 14 days of exposure and a dose-related toxic nephropathy was observed at dose of 50 mg/kg or higher." | 1.28 | Application of molecular encapsulation for toxicology studies: comparative toxicity of p-Chloro-alpha, alpha, alpha-trifluorotoluene in alpha-cyclodextrin vehicle versus corn oil vehicle in male and female Fischer 344 rats and B6C3F1 mice. ( Carlton, T; Corniffe, G; Elwell, MR; Goehl, TJ; Jameson, CW; Leininger, JR; Thompson, MB; Yuan, J, 1992) |
| "Toluene was administered orally by stomac tube in doses of 200, 400 or 800 mg/kg daily for 5 weeks or by inhalation at a concentration of 2000 p." | 1.28 | Effect of toluene on ethanol preference in rats. ( Kjaer, V; Ladefoged, O; Larsen, JJ, 1990) |
| "Toluene induction was already well developed in the youngest age group of both sexes; in most cases the induced enzyme levels in young rats were as high or higher than in adults." | 1.27 | Age-and sex-related differences in rat liver microsomal enzymes and their inducibility by toluene. ( Pyykkö, K, 1983) |
| "Benzene was more effective at inducing conjugation enzymes." | 1.27 | A comparative study of the effects of benzene, toluene, and xylenes on their in vitro metabolism and drug-metabolizing enzymes in rat liver. ( Brammer, JD; Pathiratne, A; Puyear, RL, 1986) |
| " There was a linear increase in plasma concentration of T and M during incremental dosing with 50--200 mg t." | 1.26 | A clinical and pharmacokinetic evaluation of tolmesoxide in hypertensive patients. ( Freestone, S; Phillips, FC; Ramsay, LE; Silas, JH; Tucker, GT, 1981) |
| "Toluene was found to inhibit growth but to cause no abnormal light-microscopical changes." | 1.26 | Effect of toluene inhalation on the liver of rats--dependence on sex dose and exposure time. ( Cseh, RJ; Folly, G; Mányay, S; Molnár, J; Szeberényi, S; Tátray, E; Ungváry, G, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (45.74) | 18.7374 |
| 1990's | 21 (22.34) | 18.2507 |
| 2000's | 21 (22.34) | 29.6817 |
| 2010's | 9 (9.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cosnier, F | 1 |
| Nunge, H | 1 |
| Bonfanti, É | 1 |
| Grossmann, S | 1 |
| Lambert-Xollin, AM | 1 |
| Muller, S | 1 |
| Sébillaud, S | 1 |
| Thomas, A | 1 |
| Gaté, L | 1 |
| Campo, P | 1 |
| Crossin, R | 2 |
| Lawrence, AJ | 4 |
| Andrews, ZB | 2 |
| Churilov, L | 1 |
| Duncan, JR | 4 |
| Sims, NA | 1 |
| Pang, T | 1 |
| Mathai, M | 1 |
| Gooi, JH | 1 |
| Stefanidis, A | 1 |
| Oldfield, BJ | 1 |
| Gui, WF | 1 |
| Xu, S | 1 |
| Dang, ZS | 1 |
| Zhao, YM | 1 |
| Dick, AL | 2 |
| Axelsson, M | 1 |
| Homayounfar, R | 1 |
| Jeddi-Tehrani, M | 1 |
| Cheraghpour, M | 1 |
| Ghorbani, A | 1 |
| Zand, H | 1 |
| Martínez-Alfaro, M | 1 |
| Cárabez-Trejo, A | 1 |
| Gallegos-Corona, MA | 1 |
| Pedraza-Aboytes, G | 1 |
| Hernández-Chan, NG | 1 |
| Leo-Amador, GE | 1 |
| Tu, YF | 1 |
| Lu, PJ | 1 |
| Huang, CC | 1 |
| Ho, CJ | 1 |
| Chou, YP | 1 |
| Gauthereau-Torres, MY | 1 |
| Martínez-Revollar, G | 1 |
| Plancarte-Miranda, M | 1 |
| Girón-Abarca, L | 1 |
| Campos-Campos, B | 1 |
| Mercado-Camargo, R | 1 |
| Funada, M | 1 |
| Sato, M | 1 |
| Makino, Y | 1 |
| Wada, K | 1 |
| Wiaderna, D | 1 |
| Tomas, T | 1 |
| Soulage, C | 2 |
| Perrin, D | 1 |
| Berenguer, P | 2 |
| Pequignot, JM | 2 |
| Levitt, DG | 1 |
| Fautrel, A | 1 |
| Abraini, JH | 1 |
| Ishigami, A | 1 |
| Tokunaga, I | 2 |
| Kubo, S | 2 |
| Gotohda, T | 2 |
| Chen, HH | 1 |
| Wei, CT | 1 |
| Lin, YR | 1 |
| Chien, TH | 1 |
| Chan, MH | 1 |
| Nong, A | 1 |
| McCarver, DG | 1 |
| Hines, RN | 1 |
| Krishnan, K | 2 |
| Roberts, LG | 1 |
| Nicolich, MJ | 2 |
| Schreiner, CA | 1 |
| Win-Shwe, TT | 1 |
| Tsukahara, S | 1 |
| Ahmed, S | 1 |
| Fukushima, A | 1 |
| Yamamoto, S | 1 |
| Kakeyama, M | 1 |
| Nakajima, D | 1 |
| Goto, S | 1 |
| Kobayashi, T | 1 |
| Fujimaki, H | 1 |
| Bushnell, PJ | 1 |
| Oshiro, WM | 1 |
| Samsam, TE | 1 |
| Klinger, R | 1 |
| Jarosz, PA | 1 |
| Fata, E | 1 |
| Bowen, SE | 1 |
| Jen, KL | 1 |
| Coscina, DV | 1 |
| Wetmore, BA | 1 |
| Struve, MF | 1 |
| Gao, P | 1 |
| Sharma, S | 1 |
| Allison, N | 1 |
| Roberts, KC | 1 |
| Letinski, DJ | 1 |
| Bird, MG | 1 |
| Dorman, DC | 1 |
| Bazar, MA | 1 |
| Quinn, MJ | 1 |
| Mozzachio, K | 1 |
| Johnson, MS | 1 |
| Carter, FD | 1 |
| Puyear, RL | 2 |
| Brammer, JD | 2 |
| Pyykkö, K | 3 |
| Bucchi, R | 1 |
| Gramenzi, F | 1 |
| Macri', A | 1 |
| Ricciardi, C | 2 |
| Benignus, VA | 1 |
| Muller, KE | 1 |
| Barton, CN | 1 |
| Bittikofer, JA | 1 |
| Tyson, CA | 1 |
| Dilley, JV | 1 |
| Sasmore, DP | 1 |
| Spanggord, RJ | 1 |
| Newell, GW | 1 |
| Dacre, JC | 1 |
| Carlsson, A | 2 |
| Ljungquist, E | 1 |
| Silas, JH | 1 |
| Phillips, FC | 1 |
| Freestone, S | 1 |
| Tucker, GT | 1 |
| Ramsay, LE | 1 |
| Ciss, M | 1 |
| Dutertre, H | 1 |
| Huyen, N | 1 |
| Phu-Lich, N | 1 |
| Truhaut, R | 1 |
| Hakaim, AG | 1 |
| Weiss, HS | 1 |
| Ikeda, T | 1 |
| Maehara, N | 1 |
| Sadamoto, T | 1 |
| Harabuchi, I | 1 |
| Yamamura, K | 1 |
| Miyake, H | 1 |
| Tátrai, E | 1 |
| Rodics, K | 1 |
| Ungváry, G | 2 |
| Hooson, J | 1 |
| Hicks, RM | 1 |
| Grasso, P | 1 |
| Chowaniec, J | 1 |
| Mányay, S | 1 |
| Tátray, E | 1 |
| Szeberényi, S | 1 |
| Cseh, RJ | 1 |
| Molnár, J | 1 |
| Folly, G | 1 |
| Tardif, R | 1 |
| Laparé, S | 1 |
| Charest-Tardif, G | 1 |
| Brodeur, J | 1 |
| Hillefors-Berglund, M | 1 |
| Liu, Y | 1 |
| von Euler, G | 2 |
| Nakajima, T | 1 |
| Elovaara, E | 1 |
| Okino, T | 1 |
| Gelboin, HV | 1 |
| Klockars, M | 1 |
| Riihimäki, V | 2 |
| Aoyama, T | 1 |
| Vainio, H | 1 |
| Ton, TT | 1 |
| Elwell, MR | 2 |
| Morris, RW | 1 |
| Maronpot, RR | 1 |
| Sharma, HM | 1 |
| Hanna, AN | 1 |
| Kauffman, EM | 1 |
| Newman, HA | 1 |
| Burns, LA | 2 |
| Bradley, SG | 2 |
| White, KL | 2 |
| McCay, JA | 2 |
| Fuchs, BA | 2 |
| Stern, M | 2 |
| Brown, RD | 2 |
| Musgrove, DL | 2 |
| Holsapple, MP | 2 |
| Luster, MI | 2 |
| Rebert, CS | 2 |
| Schwartz, RW | 1 |
| Svendsgaard, DJ | 1 |
| Pryor, GT | 3 |
| Boyes, WK | 1 |
| Pierce, CH | 1 |
| Dills, RL | 1 |
| Morgan, MS | 1 |
| Nothstein, GL | 1 |
| Shen, DD | 1 |
| Kalman, DA | 1 |
| Tap, O | 1 |
| Solmaz, S | 1 |
| Polat, S | 1 |
| Mete, UO | 1 |
| Ozbilgïn, MK | 1 |
| Kaya, M | 1 |
| Mortensen, B | 1 |
| Nilsen, OG | 1 |
| Yu, IJ | 1 |
| Lee, JY | 1 |
| Chung, YH | 1 |
| Kim, KJ | 1 |
| Han, JH | 1 |
| Cha, GY | 1 |
| Chung, WG | 1 |
| Cha, YN | 1 |
| Park, JD | 1 |
| Lee, YM | 1 |
| Moon, YH | 1 |
| von Euler, M | 1 |
| Pham, TM | 1 |
| Hillefors, M | 1 |
| Bjelke, B | 1 |
| Henriksson, B | 1 |
| Palermo-Neto, J | 1 |
| Santos, FA | 1 |
| Guerra, JL | 1 |
| Santos, GO | 1 |
| Pinheiro, SR | 1 |
| Dalgaard, M | 1 |
| Hossaini, A | 1 |
| Hougaard, KS | 2 |
| Hass, U | 2 |
| Ladefoged, O | 3 |
| Zhang, S | 1 |
| Cawley, GF | 1 |
| Eyer, CS | 1 |
| Backes, WL | 1 |
| Edelfors, S | 3 |
| Verschuuren, HG | 1 |
| Kroes, R | 1 |
| Den Tonkelaar, EM | 1 |
| Pfäffli, P | 1 |
| Lindqvist, T | 1 |
| Wahlberg, JE | 1 |
| Deyl, Z | 1 |
| Juricová, M | 1 |
| Stuchlíková, E | 1 |
| Yuan, J | 1 |
| Jameson, CW | 1 |
| Goehl, TJ | 1 |
| Leininger, JR | 1 |
| Thompson, MB | 1 |
| Corniffe, G | 1 |
| Carlton, T | 1 |
| Johnson, AC | 1 |
| Slomianka, L | 1 |
| Ravn-Jonsen, A | 2 |
| Rungby, J | 1 |
| Danscher, G | 1 |
| West, MJ | 1 |
| Strange, P | 1 |
| Møller, A | 1 |
| Lam, HR | 1 |
| Ostergaard, G | 1 |
| Larsen, JJ | 2 |
| Arlien-Søborg, P | 1 |
| Kjaer, V | 1 |
| da-Silva, VA | 1 |
| Malheiros, LR | 1 |
| Bueno, FM | 1 |
| Huang, J | 1 |
| Kato, K | 1 |
| Shibata, E | 1 |
| Hisanaga, N | 1 |
| Ono, Y | 1 |
| Takeuchi, Y | 1 |
| Pathiratne, A | 1 |
| Kurosaki, T | 1 |
| Kawashima, K | 1 |
| Nakaura, S | 1 |
| Tanaka, S | 1 |
| Djajalaksana, S | 1 |
| Takanaka, A | 1 |
| Arito, H | 1 |
| Tsuruta, H | 1 |
| Kyrklund, T | 1 |
| Kjellstrand, P | 1 |
| Haglid, K | 1 |
| Macrì, A | 1 |
| Stazi, AV | 1 |
| Mantovani, A | 1 |
| Vendramin Macrì, C | 1 |
| Piccioni, A | 1 |
| Badellino, E | 1 |
| Bianchi, MP | 1 |
| Pepe, M | 1 |
| Ceccanti, M | 1 |
| Ikeda, M | 1 |
| Koizumi, A | 1 |
| Kasahara, M | 1 |
| Fujita, H | 1 |
| Howd, RA | 1 |
| Uyeno, ET | 1 |
| Thurber, AB | 1 |
| Hansson, T | 1 |
| Pettersson, BM | 1 |
| Eneroth, P | 1 |
| Gustafsson, JA | 1 |
| Goldberg, J | 1 |
| Gardos, G | 1 |
| Cole, JO | 1 |
| Jus, A | 1 |
| Pineau, R | 1 |
| Jus, K | 1 |
| Villeneuve, A | 1 |
| Gautier, J | 1 |
| Pires, P | 1 |
| Drolet, A | 1 |
| Cote, M | 1 |
| Villeneuve, R | 1 |
| Ahlenius, S | 1 |
| Brown, R | 1 |
| Engel, J | 2 |
| Lundborg, P | 2 |
| Epstein, SS | 1 |
| Joshi, S | 1 |
| Andrea, J | 1 |
| Clapp, P | 1 |
| Flak, H | 1 |
| Mantel, N | 1 |
| Pascal, G | 1 |
| Terroine, T | 1 |
| Wilson, RB | 1 |
| Kula, NS | 1 |
| Newberne, PM | 2 |
| Conner, MW | 1 |
| Creaven, PJ | 1 |
| Davies, WH | 1 |
| Williams, RT | 1 |
| Kinkel, HF | 1 |
| Holzmann, S | 1 |
| Takeuchi, N | 1 |
| Yamamura, Y | 1 |
| Jenkins, LJ | 1 |
| Jones, RA | 1 |
| Siegel, J | 1 |
| Kohn, RR | 1 |
| Johnson, JC | 1 |
| Bowman, MC | 1 |
| Leuck, DB | 1 |
| Knox, FE | 1 |
| Bresnahan, MR | 1 |
| Kula, N | 1 |
2 reviews available for toluene and Body Weight
| Article | Year |
|---|---|
Growth changes after inhalant abuse and toluene exposure: A systematic review and meta-analysis of human and animal studies.
Topics: Animals; Body Height; Body Weight; Humans; Inhalant Abuse; Solvents; Toluene | 2019 |
Methionine, vitamin E, and selenium toxicity.
Topics: Aniline Compounds; Animal Feed; Animals; Antioxidants; Body Weight; Female; Food Additives; Liver; M | 1971 |
2 trials available for toluene and Body Weight
| Article | Year |
|---|---|
A controlled evaluation of pyrovalerone in chronically fatigued volunteers.
Topics: Blood Pressure; Body Weight; Central Nervous System Stimulants; Clinical Trials as Topic; Fatigue; F | 1973 |
Penfluridol: a long-acting oral neuroleptic as therapeutic agent in chronic schizophrenia.
Topics: Adult; Analysis of Variance; Basal Ganglia Diseases; Body Weight; Chlorpromazine; Chronic Disease; C | 1974 |
90 other studies available for toluene and Body Weight
| Article | Year |
|---|---|
Toluene and methylethylketone: effect of combined exposure on their metabolism in rat.
Topics: Animals; Biological Assay; Body Weight; Brain; Butanones; Inhalation Exposure; Liver; Male; Organ Si | 2018 |
Adolescent Inhalant Abuse Results in Adrenal Dysfunction and a Hypermetabolic Phenotype with Persistent Growth Impairments.
Topics: Adolescent; Adolescent Behavior; Adolescent Development; Adrenal Gland Diseases; Adrenal Glands; Ani | 2018 |
In Vitro and in Vivo Effect of MAPK Signal Transduction Pathway Inhibitors on Echinococcus multilocularis.
Topics: Albendazole; Animals; Anthelmintics; Benzamides; Body Weight; Cell Line; Disease Models, Animal; Ech | 2019 |
Specific impairments in instrumental learning following chronic intermittent toluene inhalation in adolescent rats.
Topics: Administration, Inhalation; Aging; Animals; Body Weight; Conditioning, Operant; Cues; Dietary Sucros | 2014 |
Relationship of p53 accumulation in peripheral tissues of high-fat diet-induced obese rats with decrease in metabolic and oncogenic signaling of insulin.
Topics: Adipose Tissue; Adiposity; Animals; Benzothiazoles; Body Weight; Diet, High-Fat; Fluorescent Antibod | 2015 |
Chronic intermittent toluene inhalation initiated during adolescence in rats does not alter voluntary consumption of ethanol in adulthood.
Topics: Administration, Inhalation; Age Factors; Alcohol Dehydrogenase; Alcohol Drinking; Animals; Body Weig | 2014 |
Thinner inhalation effects on oxidative stress and DNA repair in a rat model of abuse.
Topics: Animals; Biomarkers; Body Weight; Bone Marrow; Disease Models, Animal; DNA Damage; DNA Repair; Inhal | 2010 |
Moderate dietary restriction reduces p53-mediated neurovascular damage and microglia activation after hypoxic ischemia in neonatal brain.
Topics: Animals; Animals, Newborn; Apoptosis; Benzothiazoles; Blood-Brain Barrier; Blotting, Western; Body W | 2012 |
Effects of chronic solvent abuse exposure on umami taste perception.
Topics: Animals; Benzene; Body Weight; Eating; Glutamic Acid; Male; Rats; Rats, Wistar; Solvents; Taste Perc | 2009 |
Evaluation of rewarding effect of toluene by the conditioned place preference procedure in mice.
Topics: Administration, Inhalation; Animals; Atmosphere Exposure Chambers; Behavior, Animal; Body Weight; Br | 2002 |
Assessment of long-term effects of exposure to toluene based on the analysis of selected behavioral responses with particular reference to the ability to trigger behavioral hypersensitivity in rats.
Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Body Weight; Dopamine; Inhalation Exposu | 2002 |
Sub-chronic exposure to toluene at 40 ppm alters the monoamine biosynthesis rate in discrete brain areas.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Monoamines; Body Weight; Brain Chemistry; Cerebellum; Female; | 2004 |
Physiologically based pharmacokinetic modeling of arterial - antecubital vein concentration difference.
Topics: Acetone; Adult; Algorithms; Arteries; Body Weight; Deuterium Oxide; Drug Administration Schedule; El | 2004 |
Behavioral and neurochemical effects induced by subchronic combined exposure to toluene at 40 ppm and noise at 80 dB-A in rats.
Topics: Animals; Behavior, Animal; Body Weight; Brain Chemistry; Caudate Nucleus; Cytochrome P-450 CYP2E1; D | 2004 |
Immunohistochemical study of rat spermatogenesis after toluene-inhalation.
Topics: Administration, Inhalation; Animals; Apoptosis; Body Weight; Epididymis; HSP70 Heat-Shock Proteins; | 2005 |
Neonatal toluene exposure alters agonist and antagonist sensitivity and NR2B subunit expression of NMDA receptors in cultured cerebellar granule neurons.
Topics: Animals; Animals, Newborn; Blotting, Western; Body Weight; Calcium Signaling; Cerebellum; Dose-Respo | 2005 |
Toluene inhalation-induced adrenocortical hypertrophy and endocrinological changes in rat.
Topics: Administration, Inhalation; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Body Weight; Cell | 2005 |
Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.
Topics: Administration, Inhalation; Adolescent; Age Factors; Area Under Curve; Body Weight; Child; Child, Pr | 2006 |
Developmental and reproductive toxicity evaluation of toluene vapor in the rat II. Developmental toxicity.
Topics: Abnormalities, Drug-Induced; Air Pollutants; Animals; Body Weight; Bone and Bones; Dose-Response Rel | 2007 |
Athymic nude mice are insensitive to low-level toluene-induced up-regulation of memory-related gene expressions in the hippocampus.
Topics: Animals; Body Weight; CD3 Complex; Cell Count; DNA, Complementary; Female; Gene Expression; Hippocam | 2007 |
The role of physical activity and feeding schedule on the kinetics of inhaled and oral toluene in rats.
Topics: Administration, Inhalation; Administration, Oral; Animals; Body Weight; Conditioning, Operant; Male; | 2007 |
Effects of abuse pattern of gestational toluene exposure on metabolism, feeding and body composition.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Body Composition; Body Weight; Do | 2008 |
Genotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice.
Topics: Animals; Atmosphere Exposure Chambers; Benzene; Benzene Derivatives; Body Weight; Bone Marrow Cells; | 2008 |
Toxicological responses of red-backed salamanders (Plethodon cinereus) to subchronic soil exposures of 2,4,6-trinitrotoluene.
Topics: Animals; Body Weight; Color; Hematology; Soil Pollutants; Spleen; Toluene; Trinitrotoluene; Urodela | 2008 |
Effects of Aroclor 1254 treatment on the in vitro hepatic metabolism of toluene, aniline and aminopyrine in hybrid sunfish.
Topics: Aminopyrine; Aniline Compounds; Aniline Hydroxylase; Animals; Aroclors; Body Weight; Chlorodiphenyl | 1984 |
Time-course of effects of toluene on microsomal enzymes in rat liver, kidney and lung during and after inhalation exposure.
Topics: Animals; Body Weight; Cytochrome P-450 Enzyme System; Kidney; Lung; Male; Microsomes; Microsomes, Li | 1983 |
Age-and sex-related differences in rat liver microsomal enzymes and their inducibility by toluene.
Topics: Aging; Animals; Body Weight; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Liver; Male; | 1983 |
[Subchronic oral toxicity in the rat of 3-nitro-4-chloro-alpha,alpha,alpha-trifluorotoluene (NCTT)].
Topics: Animals; Blood Chemical Analysis; Body Weight; Heart; Liver; Male; Organ Size; Pancreas; Rats; Rats, | 1983 |
Toluene blood level following subcutaneous injection of toluene in the rat.
Topics: Animals; Body Weight; Injections, Subcutaneous; Models, Biological; Rats; Statistics as Topic; Tolue | 1984 |
Effects of methylbenzenes on microsomal enzymes in rat liver, kidney and lung.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzene Deri | 1980 |
Single-dose and repeated-exposure toxicity of a complex wastewater from munitions manufacturing plants.
Topics: Animals; Atrophy; Body Weight; Dogs; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Male; | 1982 |
Exposure to toluene: concentration in subcutaneous adipose tissue.
Topics: Adipose Tissue; Adult; Body Weight; Humans; Male; Physical Exertion; Respiration; Toluene | 1982 |
A clinical and pharmacokinetic evaluation of tolmesoxide in hypertensive patients.
Topics: Adult; Aged; Body Weight; Female; Hemodynamics; Humans; Hypertension; Kinetics; Male; Middle Aged; S | 1981 |
[Toxicological study of nitrotoluenes: acute toxicity and sub-acute toxicity].
Topics: Animals; Body Weight; Female; Lethal Dose 50; Male; Rats; Toluene | 1980 |
The interaction of topically applied toluene and ambient temperature on O2 uptake of tissue homogenates.
Topics: Administration, Topical; Animals; Body Temperature; Body Weight; Male; Mice; Oxygen Consumption; Tem | 1981 |
Effects of toluene exposure on the rest-activity cycle of rats.
Topics: Animals; Body Weight; Circadian Rhythm; Male; Motor Activity; Rats; Rats, Inbred Strains; Toluene | 1981 |
Embryotoxic effects of simultaneously applied exposure of benzene and toluene.
Topics: Abnormalities, Drug-Induced; Animals; Benzene; Body Weight; Female; Fetal Growth Retardation; Fetus; | 1980 |
Ortho-toluene sulphonamide and saccharin in the promotion of bladder cancer in the rat.
Topics: Animals; Body Weight; Drinking; Eating; Female; Kidney; Methylnitrosourea; Neoplasms, Experimental; | 1980 |
Effect of toluene inhalation on the liver of rats--dependence on sex dose and exposure time.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Female; Liver; Male; Organ Size; Rats; Sex F | 1980 |
Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans.
Topics: Animals; Body Weight; Computer Simulation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; | 1995 |
Persistent, specific and dose-dependent effects of toluene exposure on dopamine D2 agonist binding in the rat caudate-putamen.
Topics: Aging; Analysis of Variance; Animals; Binding, Competitive; Body Weight; Caudate Nucleus; Dopamine A | 1995 |
Different contributions of cytochrome P450 2E1 and P450 2B1/2 to chloroform hepatotoxicity in rat.
Topics: Alanine Transaminase; Animals; Antibodies, Monoclonal; Antibody Formation; Aryl Hydrocarbon Hydroxyl | 1995 |
Development and persistence of placental glutathione-S-transferase-positive foci in livers of male F344 rats exposed to o-nitrotoluene.
Topics: Animals; Body Weight; Carcinogens; Glutathione Transferase; Isoenzymes; Liver Neoplasms; Liver Neopl | 1995 |
Effect of herbal mixture student Rasayana on lipoxygenase activity and lipid peroxidation.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Humans; Lipid Peroxidation; Lipoxygenase; Ma | 1995 |
Immunotoxicity of mono-nitrotoluenes in female B6C3F1 mice: I. Para-nitrotoluene.
Topics: Administration, Oral; Animals; Antigen-Antibody Reactions; Antigens; B-Lymphocytes; Body Weight; Bon | 1994 |
Immunotoxicity of mono-nitrotoluenes in female B6C3F1 mice: II. Meta-nitrotoluene.
Topics: Administration, Oral; Animals; Antibody Formation; Antigens; Blood Cells; Body Weight; Bone Marrow; | 1994 |
Combined effects of paired solvents on the rat's auditory system.
Topics: Administration, Inhalation; Animals; Audiometry, Evoked Response; Auditory Pathways; Body Weight; Ch | 1995 |
Interindividual differences in 2H8-toluene toxicokinetics assessed by semiempirical physiologically based model.
Topics: Absorption; Adipose Tissue; Adult; Aging; Blood-Air Barrier; Body Weight; Computer Simulation; Envir | 1996 |
The effect of toluene on the rat ovary: an ultrastructural study.
Topics: Animals; Body Weight; Estrogen Antagonists; Female; Ovary; Progesterone; Rats; Rats, Wistar; Toluene | 1996 |
Allometric species comparison of toluene and n-hexane metabolism: prediction of hepatic clearance in man from experiments with rodent liver S9 in a head space vial equilibration system.
Topics: Adult; Animals; Body Weight; Hexanes; Humans; Liver; Male; Metabolic Clearance Rate; Mice; Toluene | 1998 |
Co-administration of toluene and xylene antagonized the testicular toxicity but not the hematopoietic toxicity caused by ethylene glycol monoethyl ether in Sprague-Dawley rats.
Topics: Animals; Body Weight; Enzymes; Ethylene Glycols; Genitalia; Hematopoietic System; Male; Organ Size; | 1999 |
Inhalation of low concentrations of toluene induces persistent effects on a learning retention task, beam-walk performance, and cerebrocortical size in the rat.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Body W | 2000 |
Glue solvent inhalation impairs host resistance to Mycobacterium bovis-induced infection in hamsters.
Topics: Animals; Atmosphere Exposure Chambers; Body Weight; Cricetinae; Hexanes; Immune System; Liver; Lung; | 2001 |
Developmental toxicity of toluene in male rats: effects on semen quality, testis morphology, and apoptotic neurodegeneration.
Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Animals; Animals, Newborn; Apoptosis; Body | 2001 |
Altered ethylbenzene-mediated hepatic CYP2E1 expression in growth hormone-deficient dwarf rats.
Topics: Animals; Benzene Derivatives; Blotting, Northern; Blotting, Western; Body Weight; Cytochrome P-450 C | 2002 |
Changes in markers of oxidative stress and membrane properties in synaptosomes from rats exposed prenatally to toluene.
Topics: Animals; Body Weight; Cell Membrane; Female; Maternal-Fetal Exchange; Oxidative Stress; Pregnancy; P | 2002 |
Short-term oral and dermal toxicity of MCPA and MCPP.
Topics: Administration, Oral; Animals; Behavior, Animal; Body Weight; Chlorobenzenes; Enzymes; Erythema; Fee | 1975 |
Percutaneous absorption of solvent vapors in man.
Topics: Adult; Atmosphere Exposure Chambers; Body Height; Body Surface Area; Body Weight; Humans; Lung; Male | 1978 |
Exposure of animals and man to toluene.
Topics: Adipose Tissue; Adult; Air Pollutants; Animals; Body Weight; Environmental Exposure; Humans; Male; P | 1977 |
Percutaneous toxicity of solvents. A comparative investigation in the guinea pig with benzene, toluene and 1,1,2-trichloroethane.
Topics: Animals; Benzene; Body Weight; Female; Guinea Pigs; Hydrocarbons, Chlorinated; Male; Methods; Skin; | 1976 |
The effect of nutritional regimes upon collagen concentration and survival of rats.
Topics: Age Factors; Animals; Body Weight; Collagen; Cricetinae; Diet; Ethyl Ethers; Food Deprivation; Kidne | 1975 |
Application of molecular encapsulation for toxicology studies: comparative toxicity of p-Chloro-alpha, alpha, alpha-trifluorotoluene in alpha-cyclodextrin vehicle versus corn oil vehicle in male and female Fischer 344 rats and B6C3F1 mice.
Topics: alpha-Cyclodextrins; Alpha-Globulins; Animals; Blood Cell Count; Body Weight; Capsules; Corn Oil; Cy | 1992 |
Auditory sensitivity in rats exposed to toluene and/or acetyl salicylic acid.
Topics: Acoustic Stimulation; Animals; Aspirin; Body Weight; Drug Synergism; Evoked Potentials, Auditory, Br | 1992 |
Interactive effects of toluene and hexane on behavior and neurophysiologic responses in Fischer-344 rats.
Topics: Action Potentials; Animals; Avoidance Learning; Behavior, Animal; Body Weight; Conditioning, Operant | 1992 |
The effect of low-level toluene exposure on the developing hippocampal region of the rat: histological evidence and volumetric findings.
Topics: Animals; Animals, Newborn; Body Weight; Hippocampus; Male; Rats; Rats, Inbred Strains; Staining and | 1990 |
Effects of simultaneous ethanol and toluene exposure on nerve cells measured by changes in synaptosomal calcium uptake and (Ca2+/Mg2+)-ATPase activity.
Topics: Animals; Body Weight; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Radioisotopes; Calcium-Transporting ATP | 1991 |
Irreversible effects in rats of toluene (inhalation) exposure for six months.
Topics: Administration, Inhalation; Animals; Biogenic Amines; Body Weight; Cerebral Cortex; Chromatography, | 1991 |
Effect of toluene on ethanol preference in rats.
Topics: Administration, Inhalation; Administration, Oral; Alcohol Drinking; Animals; Behavior, Animal; Body | 1990 |
Effects of toluene exposure during gestation on neurobehavioral development of rats and hamsters.
Topics: Animals; Behavior, Animal; Body Weight; Cricetinae; Female; Litter Size; Male; Mesocricetus; Pregnan | 1990 |
Effects of subacute toluene exposure on neuronal and glial marker proteins in rat brain.
Topics: Animals; Biomarkers; Body Weight; Brain; Creatine Kinase; Immunoenzyme Techniques; Isoenzymes; Male; | 1990 |
A comparative study of the effects of benzene, toluene, and xylenes on their in vitro metabolism and drug-metabolizing enzymes in rat liver.
Topics: Animals; Benzene; Body Weight; Chromatography, Gas; Cytochrome P-450 Enzyme System; Enzyme Induction | 1986 |
[Effects of dibenzyltoluene on fetal developments of rats].
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Dose-Response Relationship, Drug; | 1988 |
Increased water drinking following repeated exposures to toluene vapor in rats.
Topics: Animals; Body Weight; Diuresis; Drinking Behavior; Male; Rats; Rats, Inbred Strains; Toluene; Water- | 1988 |
Brain lipid changes in rats exposed to xylene and toluene.
Topics: Animals; Atmosphere Exposure Chambers; Body Weight; Brain; Cholesterol; Liver; Male; Organ Size; Pho | 1987 |
Subchronic oral toxicity of 4-chloro-alpha, alpha, alpha-trifluorotoluene in Sprague-Dawley rats.
Topics: Administration, Oral; Animals; Body Weight; Dose-Response Relationship, Drug; Female; Kidney Disease | 1987 |
Combined effects of n-hexane and toluene on norepinephrine and dopamine levels in rat brain tissues after long-term exposures.
Topics: Animals; Body Weight; Brain Chemistry; Dopamine; Hexanes; Male; Norepinephrine; Rats; Rats, Inbred S | 1986 |
Interactions between toluene and alcohol.
Topics: Alcohol Drinking; Animals; Blood Chemical Analysis; Body Weight; Choice Behavior; Conditioning, Oper | 1985 |
Neonatal exposure to toluene: effects on the development of liver microsomal cytochrome P-450 and serum hormone levels in the rat.
Topics: Androstenedione; Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Atmosphere Exposure Chamb | 1985 |
Learning deficits in 4 weeks old offspring of the nursing mothers treated with the neuroleptic drug penfluridol.
Topics: Age Factors; Animals; Animals, Newborn; Avoidance Learning; Body Weight; Breast Feeding; Female; Glu | 1973 |
Regional changes in monoamine levels and in the rate of tyrosine and tryptophan hydroxylation in 4 week old offspring of nursing mothers treated with the neuroleptic drug penfluridol.
Topics: 5-Hydroxytryptophan; Age Factors; Animals; Animals, Newborn; Biogenic Amines; Body Weight; Brain; Br | 1974 |
Synergistic toxicity and carcinogenicity of 'freons' and piperonyl butoxide.
Topics: Animals; Body Weight; Carcinogens; Carcinoma, Hepatocellular; Drug Synergism; Female; Halogens; Live | 1967 |
[Influence of butyl-hydroxy-toluene (BHT) on the cytochrome oxidase activity in rat liver].
Topics: Animals; Antioxidants; Body Weight; Diet; Electron Transport Complex IV; Female; Liver; Male; Organ | 1969 |
Vascular damage and lipid peroxidation in choline-deficient rats.
Topics: Animals; Anisoles; Aorta; Arteries; Barbiturates; Body Weight; Cholesterol, Dietary; Choline Deficie | 1973 |
The effect of butylated hydroxytoluene, butylated hydroxyanisole and octyl gallate upon liver weight and biphenyl 4-hydroxylase activity in the rat.
Topics: Animals; Body Weight; Butyrates; Diet; Dietary Fats; Gallic Acid; Liver; Male; Microsomes; Mixed Fun | 1966 |
Study of long-term percutaneous toxicity and carcinogenicity of hair dyes (oxidizing dyes) in rats.
Topics: Administration, Topical; Alanine Transaminase; Animals; Anisoles; Behavior, Animal; Blood Cell Count | 1973 |
Effects of egg yolk and moctamide on serum lipids in man.
Topics: Adolescent; Adult; Amides; Anticholesteremic Agents; Appetite; Autoanalysis; Body Weight; Cholestero | 1974 |
Long-term inhalation screening studies of benzene, toluene, o-xylene, and cumene on experimental animals.
Topics: Aerosols; Animals; Benzene; Blood Cells; Blood Chemical Analysis; Body Weight; Dogs; Female; Guinea | 1970 |
Effect of antioxidants on life-span of C57BL mice.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Body Weight; Environment; | 1971 |
Persistence of Phosvel in corn silage and effects of feeding dairy cows the treated silage.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cattle; Cholinesteras | 1971 |
Effects of two synthetic antioxidants, vitamin E, and ascorbic acid on the choline-deficient rat.
Topics: Animals; Antioxidants; Aorta; Ascorbic Acid; Body Weight; Cholesterol; Choline Deficiency; Coronary | 1969 |