Page last updated: 2024-10-20

toluene and Body Weight

toluene has been researched along with Body Weight in 94 studies

methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" These studies explored the effects of brief, repeated, prenatal toluene exposures in pregnant female rats on body weight, metabolic rate, body composition, and food intake in their offspring."3.74Effects of abuse pattern of gestational toluene exposure on metabolism, feeding and body composition. ( Bowen, SE; Coscina, DV; Fata, E; Jarosz, PA; Jen, KL, 2008)
"The present study was undertaken in order to investigate if toluene induced oxidative stress in brains from rats exposed prenatally to 1800 ppm toluene 6 hr/day at days 7-20 during the pregnancy."3.71Changes in markers of oxidative stress and membrane properties in synaptosomes from rats exposed prenatally to toluene. ( Edelfors, S; Hass, U; Hougaard, KS, 2002)
" Individual measurements of age, ventilation rate, blood/air partition coefficient, body weight, and adipose tissue fraction were made on 26 male subjects exposed to 50 ppm 2H8-toluene and 50 ppm toluene for 2 hr at rest, with collection of venous blood samples for 120 hr postexposure."3.69Interindividual differences in 2H8-toluene toxicokinetics assessed by semiempirical physiologically based model. ( Dills, RL; Kalman, DA; Morgan, MS; Nothstein, GL; Pierce, CH; Shen, DD, 1996)
"Toluene exposure was negatively associated with body weight ( d = -0."2.61Growth changes after inhalant abuse and toluene exposure: A systematic review and meta-analysis of human and animal studies. ( Andrews, ZB; Churilov, L; Crossin, R; Duncan, JR; Lawrence, AJ, 2019)
"Inhalant abuse is prevalent in adolescent populations, with chronic use resulting in neurobiological and cognitive abnormalities in adulthood."1.40Specific impairments in instrumental learning following chronic intermittent toluene inhalation in adolescent rats. ( Axelsson, M; Dick, AL; Duncan, JR; Lawrence, AJ, 2014)
"Benzene is an important industrial chemical."1.35Genotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice. ( Allison, N; Bird, MG; Dorman, DC; Gao, P; Letinski, DJ; Nicolich, MJ; Roberts, KC; Sharma, S; Struve, MF; Wetmore, BA, 2008)
" At Caesarean section on GD20, no adverse effects on implantation, number and viability of fetuses, or fetal sex distribution were observed."1.34Developmental and reproductive toxicity evaluation of toluene vapor in the rat II. Developmental toxicity. ( Nicolich, MJ; Roberts, LG; Schreiner, CA, 2007)
" Another group of "conditioned-sedentary" (C-S) rats was dosed similarly but did not perform the LPT."1.34The role of physical activity and feeding schedule on the kinetics of inhaled and oral toluene in rats. ( Bushnell, PJ; Klinger, R; Oshiro, WM; Samsam, TE, 2007)
"Body weight was significantly decreased in the toluene group (P < 0."1.33Immunohistochemical study of rat spermatogenesis after toluene-inhalation. ( Gotohda, T; Ishigami, A; Kubo, S; Tokunaga, I, 2005)
"Toluene has been reported to antagonize the function of N-methyl-D-aspartate (NMDA) receptors."1.33Neonatal toluene exposure alters agonist and antagonist sensitivity and NR2B subunit expression of NMDA receptors in cultured cerebellar granule neurons. ( Chan, MH; Chen, HH; Chien, TH; Lin, YR; Wei, CT, 2005)
" The methodology involved the use of a previously validated physiologically based pharmacokinetic (PBPK) model, in which the intrinsic clearance for hepatic metabolism (CL(int)) was expressed in terms of the CYP2E1 content."1.33Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene. ( Hines, RN; Krishnan, K; McCarver, DG; Nong, A, 2006)
"Modeling of pharmacokinetic parameters and pharmacodynamic actions requires knowledge of the arterial blood concentration."1.32Physiologically based pharmacokinetic modeling of arterial - antecubital vein concentration difference. ( Levitt, DG, 2004)
"Toluene is a major component of numerous commercial organic solvent formulations."1.31Assessment of long-term effects of exposure to toluene based on the analysis of selected behavioral responses with particular reference to the ability to trigger behavioral hypersensitivity in rats. ( Tomas, T; Wiaderna, D, 2002)
"A physiologically-based pharmacokinetic (PBPK) model for a mixture of toluene (TOL) and xylene (XYL), developed and validated in the rat, was used to predict the uptake and disposition kinetics of TOL/XYL mixture in humans."1.29Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans. ( Brodeur, J; Charest-Tardif, G; Krishnan, K; Laparé, S; Tardif, R, 1995)
"Chloroform treatment did not affect the activity of N-nitrosodimethylamine N-demethylase in pretreated rats; the high dose increased the activity in control rats."1.29Different contributions of cytochrome P450 2E1 and P450 2B1/2 to chloroform hepatotoxicity in rat. ( Aoyama, T; Elovaara, E; Gelboin, HV; Klockars, M; Nakajima, T; Okino, T; Riihimäki, V; Vainio, H, 1995)
" With both vehicles CTFT and alpha 2u-globulin were found to accumulate in the male rat kidney after 14 days of exposure and a dose-related toxic nephropathy was observed at dose of 50 mg/kg or higher."1.28Application of molecular encapsulation for toxicology studies: comparative toxicity of p-Chloro-alpha, alpha, alpha-trifluorotoluene in alpha-cyclodextrin vehicle versus corn oil vehicle in male and female Fischer 344 rats and B6C3F1 mice. ( Carlton, T; Corniffe, G; Elwell, MR; Goehl, TJ; Jameson, CW; Leininger, JR; Thompson, MB; Yuan, J, 1992)
"Toluene was administered orally by stomac tube in doses of 200, 400 or 800 mg/kg daily for 5 weeks or by inhalation at a concentration of 2000 p."1.28Effect of toluene on ethanol preference in rats. ( Kjaer, V; Ladefoged, O; Larsen, JJ, 1990)
"Toluene induction was already well developed in the youngest age group of both sexes; in most cases the induced enzyme levels in young rats were as high or higher than in adults."1.27Age-and sex-related differences in rat liver microsomal enzymes and their inducibility by toluene. ( Pyykkö, K, 1983)
"Benzene was more effective at inducing conjugation enzymes."1.27A comparative study of the effects of benzene, toluene, and xylenes on their in vitro metabolism and drug-metabolizing enzymes in rat liver. ( Brammer, JD; Pathiratne, A; Puyear, RL, 1986)
" There was a linear increase in plasma concentration of T and M during incremental dosing with 50--200 mg t."1.26A clinical and pharmacokinetic evaluation of tolmesoxide in hypertensive patients. ( Freestone, S; Phillips, FC; Ramsay, LE; Silas, JH; Tucker, GT, 1981)
"Toluene was found to inhibit growth but to cause no abnormal light-microscopical changes."1.26Effect of toluene inhalation on the liver of rats--dependence on sex dose and exposure time. ( Cseh, RJ; Folly, G; Mányay, S; Molnár, J; Szeberényi, S; Tátray, E; Ungváry, G, 1980)

Research

Studies (94)

TimeframeStudies, this research(%)All Research%
pre-199043 (45.74)18.7374
1990's21 (22.34)18.2507
2000's21 (22.34)29.6817
2010's9 (9.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cosnier, F1
Nunge, H1
Bonfanti, É1
Grossmann, S1
Lambert-Xollin, AM1
Muller, S1
Sébillaud, S1
Thomas, A1
Gaté, L1
Campo, P1
Crossin, R2
Lawrence, AJ4
Andrews, ZB2
Churilov, L1
Duncan, JR4
Sims, NA1
Pang, T1
Mathai, M1
Gooi, JH1
Stefanidis, A1
Oldfield, BJ1
Gui, WF1
Xu, S1
Dang, ZS1
Zhao, YM1
Dick, AL2
Axelsson, M1
Homayounfar, R1
Jeddi-Tehrani, M1
Cheraghpour, M1
Ghorbani, A1
Zand, H1
Martínez-Alfaro, M1
Cárabez-Trejo, A1
Gallegos-Corona, MA1
Pedraza-Aboytes, G1
Hernández-Chan, NG1
Leo-Amador, GE1
Tu, YF1
Lu, PJ1
Huang, CC1
Ho, CJ1
Chou, YP1
Gauthereau-Torres, MY1
Martínez-Revollar, G1
Plancarte-Miranda, M1
Girón-Abarca, L1
Campos-Campos, B1
Mercado-Camargo, R1
Funada, M1
Sato, M1
Makino, Y1
Wada, K1
Wiaderna, D1
Tomas, T1
Soulage, C2
Perrin, D1
Berenguer, P2
Pequignot, JM2
Levitt, DG1
Fautrel, A1
Abraini, JH1
Ishigami, A1
Tokunaga, I2
Kubo, S2
Gotohda, T2
Chen, HH1
Wei, CT1
Lin, YR1
Chien, TH1
Chan, MH1
Nong, A1
McCarver, DG1
Hines, RN1
Krishnan, K2
Roberts, LG1
Nicolich, MJ2
Schreiner, CA1
Win-Shwe, TT1
Tsukahara, S1
Ahmed, S1
Fukushima, A1
Yamamoto, S1
Kakeyama, M1
Nakajima, D1
Goto, S1
Kobayashi, T1
Fujimaki, H1
Bushnell, PJ1
Oshiro, WM1
Samsam, TE1
Klinger, R1
Jarosz, PA1
Fata, E1
Bowen, SE1
Jen, KL1
Coscina, DV1
Wetmore, BA1
Struve, MF1
Gao, P1
Sharma, S1
Allison, N1
Roberts, KC1
Letinski, DJ1
Bird, MG1
Dorman, DC1
Bazar, MA1
Quinn, MJ1
Mozzachio, K1
Johnson, MS1
Carter, FD1
Puyear, RL2
Brammer, JD2
Pyykkö, K3
Bucchi, R1
Gramenzi, F1
Macri', A1
Ricciardi, C2
Benignus, VA1
Muller, KE1
Barton, CN1
Bittikofer, JA1
Tyson, CA1
Dilley, JV1
Sasmore, DP1
Spanggord, RJ1
Newell, GW1
Dacre, JC1
Carlsson, A2
Ljungquist, E1
Silas, JH1
Phillips, FC1
Freestone, S1
Tucker, GT1
Ramsay, LE1
Ciss, M1
Dutertre, H1
Huyen, N1
Phu-Lich, N1
Truhaut, R1
Hakaim, AG1
Weiss, HS1
Ikeda, T1
Maehara, N1
Sadamoto, T1
Harabuchi, I1
Yamamura, K1
Miyake, H1
Tátrai, E1
Rodics, K1
Ungváry, G2
Hooson, J1
Hicks, RM1
Grasso, P1
Chowaniec, J1
Mányay, S1
Tátray, E1
Szeberényi, S1
Cseh, RJ1
Molnár, J1
Folly, G1
Tardif, R1
Laparé, S1
Charest-Tardif, G1
Brodeur, J1
Hillefors-Berglund, M1
Liu, Y1
von Euler, G2
Nakajima, T1
Elovaara, E1
Okino, T1
Gelboin, HV1
Klockars, M1
Riihimäki, V2
Aoyama, T1
Vainio, H1
Ton, TT1
Elwell, MR2
Morris, RW1
Maronpot, RR1
Sharma, HM1
Hanna, AN1
Kauffman, EM1
Newman, HA1
Burns, LA2
Bradley, SG2
White, KL2
McCay, JA2
Fuchs, BA2
Stern, M2
Brown, RD2
Musgrove, DL2
Holsapple, MP2
Luster, MI2
Rebert, CS2
Schwartz, RW1
Svendsgaard, DJ1
Pryor, GT3
Boyes, WK1
Pierce, CH1
Dills, RL1
Morgan, MS1
Nothstein, GL1
Shen, DD1
Kalman, DA1
Tap, O1
Solmaz, S1
Polat, S1
Mete, UO1
Ozbilgïn, MK1
Kaya, M1
Mortensen, B1
Nilsen, OG1
Yu, IJ1
Lee, JY1
Chung, YH1
Kim, KJ1
Han, JH1
Cha, GY1
Chung, WG1
Cha, YN1
Park, JD1
Lee, YM1
Moon, YH1
von Euler, M1
Pham, TM1
Hillefors, M1
Bjelke, B1
Henriksson, B1
Palermo-Neto, J1
Santos, FA1
Guerra, JL1
Santos, GO1
Pinheiro, SR1
Dalgaard, M1
Hossaini, A1
Hougaard, KS2
Hass, U2
Ladefoged, O3
Zhang, S1
Cawley, GF1
Eyer, CS1
Backes, WL1
Edelfors, S3
Verschuuren, HG1
Kroes, R1
Den Tonkelaar, EM1
Pfäffli, P1
Lindqvist, T1
Wahlberg, JE1
Deyl, Z1
Juricová, M1
Stuchlíková, E1
Yuan, J1
Jameson, CW1
Goehl, TJ1
Leininger, JR1
Thompson, MB1
Corniffe, G1
Carlton, T1
Johnson, AC1
Slomianka, L1
Ravn-Jonsen, A2
Rungby, J1
Danscher, G1
West, MJ1
Strange, P1
Møller, A1
Lam, HR1
Ostergaard, G1
Larsen, JJ2
Arlien-Søborg, P1
Kjaer, V1
da-Silva, VA1
Malheiros, LR1
Bueno, FM1
Huang, J1
Kato, K1
Shibata, E1
Hisanaga, N1
Ono, Y1
Takeuchi, Y1
Pathiratne, A1
Kurosaki, T1
Kawashima, K1
Nakaura, S1
Tanaka, S1
Djajalaksana, S1
Takanaka, A1
Arito, H1
Tsuruta, H1
Kyrklund, T1
Kjellstrand, P1
Haglid, K1
Macrì, A1
Stazi, AV1
Mantovani, A1
Vendramin Macrì, C1
Piccioni, A1
Badellino, E1
Bianchi, MP1
Pepe, M1
Ceccanti, M1
Ikeda, M1
Koizumi, A1
Kasahara, M1
Fujita, H1
Howd, RA1
Uyeno, ET1
Thurber, AB1
Hansson, T1
Pettersson, BM1
Eneroth, P1
Gustafsson, JA1
Goldberg, J1
Gardos, G1
Cole, JO1
Jus, A1
Pineau, R1
Jus, K1
Villeneuve, A1
Gautier, J1
Pires, P1
Drolet, A1
Cote, M1
Villeneuve, R1
Ahlenius, S1
Brown, R1
Engel, J2
Lundborg, P2
Epstein, SS1
Joshi, S1
Andrea, J1
Clapp, P1
Flak, H1
Mantel, N1
Pascal, G1
Terroine, T1
Wilson, RB1
Kula, NS1
Newberne, PM2
Conner, MW1
Creaven, PJ1
Davies, WH1
Williams, RT1
Kinkel, HF1
Holzmann, S1
Takeuchi, N1
Yamamura, Y1
Jenkins, LJ1
Jones, RA1
Siegel, J1
Kohn, RR1
Johnson, JC1
Bowman, MC1
Leuck, DB1
Knox, FE1
Bresnahan, MR1
Kula, N1

Reviews

2 reviews available for toluene and Body Weight

ArticleYear
Growth changes after inhalant abuse and toluene exposure: A systematic review and meta-analysis of human and animal studies.
    Human & experimental toxicology, 2019, Volume: 38, Issue:2

    Topics: Animals; Body Height; Body Weight; Humans; Inhalant Abuse; Solvents; Toluene

2019
Methionine, vitamin E, and selenium toxicity.
    Nutrition reviews, 1971, Volume: 29, Issue:2

    Topics: Aniline Compounds; Animal Feed; Animals; Antioxidants; Body Weight; Female; Food Additives; Liver; M

1971

Trials

2 trials available for toluene and Body Weight

ArticleYear
A controlled evaluation of pyrovalerone in chronically fatigued volunteers.
    International pharmacopsychiatry, 1973, Volume: 8, Issue:1

    Topics: Blood Pressure; Body Weight; Central Nervous System Stimulants; Clinical Trials as Topic; Fatigue; F

1973
Penfluridol: a long-acting oral neuroleptic as therapeutic agent in chronic schizophrenia.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:10

    Topics: Adult; Analysis of Variance; Basal Ganglia Diseases; Body Weight; Chlorpromazine; Chronic Disease; C

1974

Other Studies

90 other studies available for toluene and Body Weight

ArticleYear
Toluene and methylethylketone: effect of combined exposure on their metabolism in rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 2018, Volume: 48, Issue:7

    Topics: Animals; Biological Assay; Body Weight; Brain; Butanones; Inhalation Exposure; Liver; Male; Organ Si

2018
Adolescent Inhalant Abuse Results in Adrenal Dysfunction and a Hypermetabolic Phenotype with Persistent Growth Impairments.
    Neuroendocrinology, 2018, Volume: 107, Issue:4

    Topics: Adolescent; Adolescent Behavior; Adolescent Development; Adrenal Gland Diseases; Adrenal Glands; Ani

2018
In Vitro and in Vivo Effect of MAPK Signal Transduction Pathway Inhibitors on Echinococcus multilocularis.
    The Journal of parasitology, 2019, Volume: 105, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Benzamides; Body Weight; Cell Line; Disease Models, Animal; Ech

2019
Specific impairments in instrumental learning following chronic intermittent toluene inhalation in adolescent rats.
    Psychopharmacology, 2014, Volume: 231, Issue:8

    Topics: Administration, Inhalation; Aging; Animals; Body Weight; Conditioning, Operant; Cues; Dietary Sucros

2014
Relationship of p53 accumulation in peripheral tissues of high-fat diet-induced obese rats with decrease in metabolic and oncogenic signaling of insulin.
    General and comparative endocrinology, 2015, Apr-01, Volume: 214

    Topics: Adipose Tissue; Adiposity; Animals; Benzothiazoles; Body Weight; Diet, High-Fat; Fluorescent Antibod

2015
Chronic intermittent toluene inhalation initiated during adolescence in rats does not alter voluntary consumption of ethanol in adulthood.
    Alcohol (Fayetteville, N.Y.), 2014, Volume: 48, Issue:6

    Topics: Administration, Inhalation; Age Factors; Alcohol Dehydrogenase; Alcohol Drinking; Animals; Body Weig

2014
Thinner inhalation effects on oxidative stress and DNA repair in a rat model of abuse.
    Journal of applied toxicology : JAT, 2010, Volume: 30, Issue:3

    Topics: Animals; Biomarkers; Body Weight; Bone Marrow; Disease Models, Animal; DNA Damage; DNA Repair; Inhal

2010
Moderate dietary restriction reduces p53-mediated neurovascular damage and microglia activation after hypoxic ischemia in neonatal brain.
    Stroke, 2012, Volume: 43, Issue:2

    Topics: Animals; Animals, Newborn; Apoptosis; Benzothiazoles; Blood-Brain Barrier; Blotting, Western; Body W

2012
Effects of chronic solvent abuse exposure on umami taste perception.
    Proceedings of the Western Pharmacology Society, 2009, Volume: 52

    Topics: Animals; Benzene; Body Weight; Eating; Glutamic Acid; Male; Rats; Rats, Wistar; Solvents; Taste Perc

2009
Evaluation of rewarding effect of toluene by the conditioned place preference procedure in mice.
    Brain research. Brain research protocols, 2002, Volume: 10, Issue:1

    Topics: Administration, Inhalation; Animals; Atmosphere Exposure Chambers; Behavior, Animal; Body Weight; Br

2002
Assessment of long-term effects of exposure to toluene based on the analysis of selected behavioral responses with particular reference to the ability to trigger behavioral hypersensitivity in rats.
    International journal of occupational medicine and environmental health, 2002, Volume: 15, Issue:3

    Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Body Weight; Dopamine; Inhalation Exposu

2002
Sub-chronic exposure to toluene at 40 ppm alters the monoamine biosynthesis rate in discrete brain areas.
    Toxicology, 2004, Mar-01, Volume: 196, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Monoamines; Body Weight; Brain Chemistry; Cerebellum; Female;

2004
Physiologically based pharmacokinetic modeling of arterial - antecubital vein concentration difference.
    BMC clinical pharmacology, 2004, Feb-19, Volume: 4

    Topics: Acetone; Adult; Algorithms; Arteries; Body Weight; Deuterium Oxide; Drug Administration Schedule; El

2004
Behavioral and neurochemical effects induced by subchronic combined exposure to toluene at 40 ppm and noise at 80 dB-A in rats.
    Physiology & behavior, 2004, Volume: 81, Issue:3

    Topics: Animals; Behavior, Animal; Body Weight; Brain Chemistry; Caudate Nucleus; Cytochrome P-450 CYP2E1; D

2004
Immunohistochemical study of rat spermatogenesis after toluene-inhalation.
    Legal medicine (Tokyo, Japan), 2005, Volume: 7, Issue:1

    Topics: Administration, Inhalation; Animals; Apoptosis; Body Weight; Epididymis; HSP70 Heat-Shock Proteins;

2005
Neonatal toluene exposure alters agonist and antagonist sensitivity and NR2B subunit expression of NMDA receptors in cultured cerebellar granule neurons.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 85, Issue:1

    Topics: Animals; Animals, Newborn; Blotting, Western; Body Weight; Calcium Signaling; Cerebellum; Dose-Respo

2005
Toluene inhalation-induced adrenocortical hypertrophy and endocrinological changes in rat.
    Life sciences, 2005, Mar-11, Volume: 76, Issue:17

    Topics: Administration, Inhalation; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Body Weight; Cell

2005
Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.
    Toxicology and applied pharmacology, 2006, Jul-01, Volume: 214, Issue:1

    Topics: Administration, Inhalation; Adolescent; Age Factors; Area Under Curve; Body Weight; Child; Child, Pr

2006
Developmental and reproductive toxicity evaluation of toluene vapor in the rat II. Developmental toxicity.
    Reproductive toxicology (Elmsford, N.Y.), 2007, Volume: 23, Issue:4

    Topics: Abnormalities, Drug-Induced; Air Pollutants; Animals; Body Weight; Bone and Bones; Dose-Response Rel

2007
Athymic nude mice are insensitive to low-level toluene-induced up-regulation of memory-related gene expressions in the hippocampus.
    Neurotoxicology, 2007, Volume: 28, Issue:5

    Topics: Animals; Body Weight; CD3 Complex; Cell Count; DNA, Complementary; Female; Gene Expression; Hippocam

2007
The role of physical activity and feeding schedule on the kinetics of inhaled and oral toluene in rats.
    Journal of toxicology and environmental health. Part A, 2007, Volume: 70, Issue:21

    Topics: Administration, Inhalation; Administration, Oral; Animals; Body Weight; Conditioning, Operant; Male;

2007
Effects of abuse pattern of gestational toluene exposure on metabolism, feeding and body composition.
    Physiology & behavior, 2008, Mar-18, Volume: 93, Issue:4-5

    Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Body Composition; Body Weight; Do

2008
Genotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice.
    Chemico-biological interactions, 2008, Jun-17, Volume: 173, Issue:3

    Topics: Animals; Atmosphere Exposure Chambers; Benzene; Benzene Derivatives; Body Weight; Bone Marrow Cells;

2008
Toxicological responses of red-backed salamanders (Plethodon cinereus) to subchronic soil exposures of 2,4,6-trinitrotoluene.
    Environmental toxicology and chemistry, 2008, Volume: 27, Issue:6

    Topics: Animals; Body Weight; Color; Hematology; Soil Pollutants; Spleen; Toluene; Trinitrotoluene; Urodela

2008
Effects of Aroclor 1254 treatment on the in vitro hepatic metabolism of toluene, aniline and aminopyrine in hybrid sunfish.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 78, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Aniline Hydroxylase; Animals; Aroclors; Body Weight; Chlorodiphenyl

1984
Time-course of effects of toluene on microsomal enzymes in rat liver, kidney and lung during and after inhalation exposure.
    Chemico-biological interactions, 1983, Volume: 44, Issue:3

    Topics: Animals; Body Weight; Cytochrome P-450 Enzyme System; Kidney; Lung; Male; Microsomes; Microsomes, Li

1983
Age-and sex-related differences in rat liver microsomal enzymes and their inducibility by toluene.
    Acta pharmacologica et toxicologica, 1983, Volume: 53, Issue:5

    Topics: Aging; Animals; Body Weight; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Liver; Male;

1983
[Subchronic oral toxicity in the rat of 3-nitro-4-chloro-alpha,alpha,alpha-trifluorotoluene (NCTT)].
    Annali dell'Istituto superiore di sanita, 1983, Volume: 19, Issue:2-3

    Topics: Animals; Blood Chemical Analysis; Body Weight; Heart; Liver; Male; Organ Size; Pancreas; Rats; Rats,

1983
Toluene blood level following subcutaneous injection of toluene in the rat.
    Environmental research, 1984, Volume: 33, Issue:2

    Topics: Animals; Body Weight; Injections, Subcutaneous; Models, Biological; Rats; Statistics as Topic; Tolue

1984
Effects of methylbenzenes on microsomal enzymes in rat liver, kidney and lung.
    Biochimica et biophysica acta, 1980, Nov-17, Volume: 633, Issue:1

    Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzene Deri

1980
Single-dose and repeated-exposure toxicity of a complex wastewater from munitions manufacturing plants.
    Journal of toxicology and environmental health, 1982, Volume: 9, Issue:4

    Topics: Animals; Atrophy; Body Weight; Dogs; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Male;

1982
Exposure to toluene: concentration in subcutaneous adipose tissue.
    Scandinavian journal of work, environment & health, 1982, Volume: 8, Issue:1

    Topics: Adipose Tissue; Adult; Body Weight; Humans; Male; Physical Exertion; Respiration; Toluene

1982
A clinical and pharmacokinetic evaluation of tolmesoxide in hypertensive patients.
    European journal of clinical pharmacology, 1981, Volume: 19, Issue:2

    Topics: Adult; Aged; Body Weight; Female; Hemodynamics; Humans; Hypertension; Kinetics; Male; Middle Aged; S

1981
[Toxicological study of nitrotoluenes: acute toxicity and sub-acute toxicity].
    Dakar medical, 1980, Volume: 25, Issue:4

    Topics: Animals; Body Weight; Female; Lethal Dose 50; Male; Rats; Toluene

1980
The interaction of topically applied toluene and ambient temperature on O2 uptake of tissue homogenates.
    Research communications in chemical pathology and pharmacology, 1981, Volume: 33, Issue:1

    Topics: Administration, Topical; Animals; Body Temperature; Body Weight; Male; Mice; Oxygen Consumption; Tem

1981
Effects of toluene exposure on the rest-activity cycle of rats.
    Toxicology letters, 1981, Volume: 9, Issue:3

    Topics: Animals; Body Weight; Circadian Rhythm; Male; Motor Activity; Rats; Rats, Inbred Strains; Toluene

1981
Embryotoxic effects of simultaneously applied exposure of benzene and toluene.
    Folia morphologica, 1980, Volume: 28, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Benzene; Body Weight; Female; Fetal Growth Retardation; Fetus;

1980
Ortho-toluene sulphonamide and saccharin in the promotion of bladder cancer in the rat.
    British journal of cancer, 1980, Volume: 42, Issue:1

    Topics: Animals; Body Weight; Drinking; Eating; Female; Kidney; Methylnitrosourea; Neoplasms, Experimental;

1980
Effect of toluene inhalation on the liver of rats--dependence on sex dose and exposure time.
    Journal of hygiene, epidemiology, microbiology, and immunology, 1980, Volume: 24, Issue:3

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Female; Liver; Male; Organ Size; Rats; Sex F

1980
Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans.
    Risk analysis : an official publication of the Society for Risk Analysis, 1995, Volume: 15, Issue:3

    Topics: Animals; Body Weight; Computer Simulation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System;

1995
Persistent, specific and dose-dependent effects of toluene exposure on dopamine D2 agonist binding in the rat caudate-putamen.
    Toxicology, 1995, Jun-26, Volume: 100, Issue:1-3

    Topics: Aging; Analysis of Variance; Animals; Binding, Competitive; Body Weight; Caudate Nucleus; Dopamine A

1995
Different contributions of cytochrome P450 2E1 and P450 2B1/2 to chloroform hepatotoxicity in rat.
    Toxicology and applied pharmacology, 1995, Volume: 133, Issue:2

    Topics: Alanine Transaminase; Animals; Antibodies, Monoclonal; Antibody Formation; Aryl Hydrocarbon Hydroxyl

1995
Development and persistence of placental glutathione-S-transferase-positive foci in livers of male F344 rats exposed to o-nitrotoluene.
    Cancer letters, 1995, Aug-16, Volume: 95, Issue:1-2

    Topics: Animals; Body Weight; Carcinogens; Glutathione Transferase; Isoenzymes; Liver Neoplasms; Liver Neopl

1995
Effect of herbal mixture student Rasayana on lipoxygenase activity and lipid peroxidation.
    Free radical biology & medicine, 1995, Volume: 18, Issue:4

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Humans; Lipid Peroxidation; Lipoxygenase; Ma

1995
Immunotoxicity of mono-nitrotoluenes in female B6C3F1 mice: I. Para-nitrotoluene.
    Drug and chemical toxicology, 1994, Volume: 17, Issue:3

    Topics: Administration, Oral; Animals; Antigen-Antibody Reactions; Antigens; B-Lymphocytes; Body Weight; Bon

1994
Immunotoxicity of mono-nitrotoluenes in female B6C3F1 mice: II. Meta-nitrotoluene.
    Drug and chemical toxicology, 1994, Volume: 17, Issue:3

    Topics: Administration, Oral; Animals; Antibody Formation; Antigens; Blood Cells; Body Weight; Bone Marrow;

1994
Combined effects of paired solvents on the rat's auditory system.
    Toxicology, 1995, Dec-28, Volume: 105, Issue:2-3

    Topics: Administration, Inhalation; Animals; Audiometry, Evoked Response; Auditory Pathways; Body Weight; Ch

1995
Interindividual differences in 2H8-toluene toxicokinetics assessed by semiempirical physiologically based model.
    Toxicology and applied pharmacology, 1996, Volume: 139, Issue:1

    Topics: Absorption; Adipose Tissue; Adult; Aging; Blood-Air Barrier; Body Weight; Computer Simulation; Envir

1996
The effect of toluene on the rat ovary: an ultrastructural study.
    Journal of submicroscopic cytology and pathology, 1996, Volume: 28, Issue:4

    Topics: Animals; Body Weight; Estrogen Antagonists; Female; Ovary; Progesterone; Rats; Rats, Wistar; Toluene

1996
Allometric species comparison of toluene and n-hexane metabolism: prediction of hepatic clearance in man from experiments with rodent liver S9 in a head space vial equilibration system.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:4

    Topics: Adult; Animals; Body Weight; Hexanes; Humans; Liver; Male; Metabolic Clearance Rate; Mice; Toluene

1998
Co-administration of toluene and xylene antagonized the testicular toxicity but not the hematopoietic toxicity caused by ethylene glycol monoethyl ether in Sprague-Dawley rats.
    Toxicology letters, 1999, Sep-20, Volume: 109, Issue:1-2

    Topics: Animals; Body Weight; Enzymes; Ethylene Glycols; Genitalia; Hematopoietic System; Male; Organ Size;

1999
Inhalation of low concentrations of toluene induces persistent effects on a learning retention task, beam-walk performance, and cerebrocortical size in the rat.
    Experimental neurology, 2000, Volume: 163, Issue:1

    Topics: Administration, Inhalation; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Body W

2000
Glue solvent inhalation impairs host resistance to Mycobacterium bovis-induced infection in hamsters.
    Veterinary and human toxicology, 2001, Volume: 43, Issue:1

    Topics: Animals; Atmosphere Exposure Chambers; Body Weight; Cricetinae; Hexanes; Immune System; Liver; Lung;

2001
Developmental toxicity of toluene in male rats: effects on semen quality, testis morphology, and apoptotic neurodegeneration.
    Archives of toxicology, 2001, Volume: 75, Issue:2

    Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Animals; Animals, Newborn; Apoptosis; Body

2001
Altered ethylbenzene-mediated hepatic CYP2E1 expression in growth hormone-deficient dwarf rats.
    Toxicology and applied pharmacology, 2002, Mar-01, Volume: 179, Issue:2

    Topics: Animals; Benzene Derivatives; Blotting, Northern; Blotting, Western; Body Weight; Cytochrome P-450 C

2002
Changes in markers of oxidative stress and membrane properties in synaptosomes from rats exposed prenatally to toluene.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:1

    Topics: Animals; Body Weight; Cell Membrane; Female; Maternal-Fetal Exchange; Oxidative Stress; Pregnancy; P

2002
Short-term oral and dermal toxicity of MCPA and MCPP.
    Toxicology, 1975, Volume: 3, Issue:3

    Topics: Administration, Oral; Animals; Behavior, Animal; Body Weight; Chlorobenzenes; Enzymes; Erythema; Fee

1975
Percutaneous absorption of solvent vapors in man.
    Scandinavian journal of work, environment & health, 1978, Volume: 4, Issue:1

    Topics: Adult; Atmosphere Exposure Chambers; Body Height; Body Surface Area; Body Weight; Humans; Lung; Male

1978
Exposure of animals and man to toluene.
    Scandinavian journal of work, environment & health, 1977, Volume: 3, Issue:3

    Topics: Adipose Tissue; Adult; Air Pollutants; Animals; Body Weight; Environmental Exposure; Humans; Male; P

1977
Percutaneous toxicity of solvents. A comparative investigation in the guinea pig with benzene, toluene and 1,1,2-trichloroethane.
    The Annals of occupational hygiene, 1976, Volume: 19, Issue:2

    Topics: Animals; Benzene; Body Weight; Female; Guinea Pigs; Hydrocarbons, Chlorinated; Male; Methods; Skin;

1976
The effect of nutritional regimes upon collagen concentration and survival of rats.
    Advances in experimental medicine and biology, 1975, Volume: 53

    Topics: Age Factors; Animals; Body Weight; Collagen; Cricetinae; Diet; Ethyl Ethers; Food Deprivation; Kidne

1975
Application of molecular encapsulation for toxicology studies: comparative toxicity of p-Chloro-alpha, alpha, alpha-trifluorotoluene in alpha-cyclodextrin vehicle versus corn oil vehicle in male and female Fischer 344 rats and B6C3F1 mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:3

    Topics: alpha-Cyclodextrins; Alpha-Globulins; Animals; Blood Cell Count; Body Weight; Capsules; Corn Oil; Cy

1992
Auditory sensitivity in rats exposed to toluene and/or acetyl salicylic acid.
    Neuroreport, 1992, Volume: 3, Issue:12

    Topics: Acoustic Stimulation; Animals; Aspirin; Body Weight; Drug Synergism; Evoked Potentials, Auditory, Br

1992
Interactive effects of toluene and hexane on behavior and neurophysiologic responses in Fischer-344 rats.
    Neurotoxicology, 1992,Spring, Volume: 13, Issue:1

    Topics: Action Potentials; Animals; Avoidance Learning; Behavior, Animal; Body Weight; Conditioning, Operant

1992
The effect of low-level toluene exposure on the developing hippocampal region of the rat: histological evidence and volumetric findings.
    Toxicology, 1990, May-31, Volume: 62, Issue:2

    Topics: Animals; Animals, Newborn; Body Weight; Hippocampus; Male; Rats; Rats, Inbred Strains; Staining and

1990
Effects of simultaneous ethanol and toluene exposure on nerve cells measured by changes in synaptosomal calcium uptake and (Ca2+/Mg2+)-ATPase activity.
    Pharmacology & toxicology, 1991, Volume: 69, Issue:2

    Topics: Animals; Body Weight; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Radioisotopes; Calcium-Transporting ATP

1991
Irreversible effects in rats of toluene (inhalation) exposure for six months.
    Pharmacology & toxicology, 1991, Volume: 68, Issue:5

    Topics: Administration, Inhalation; Animals; Biogenic Amines; Body Weight; Cerebral Cortex; Chromatography,

1991
Effect of toluene on ethanol preference in rats.
    Pharmacology & toxicology, 1990, Volume: 67, Issue:4

    Topics: Administration, Inhalation; Administration, Oral; Alcohol Drinking; Animals; Behavior, Animal; Body

1990
Effects of toluene exposure during gestation on neurobehavioral development of rats and hamsters.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1990, Volume: 23, Issue:6-7

    Topics: Animals; Behavior, Animal; Body Weight; Cricetinae; Female; Litter Size; Male; Mesocricetus; Pregnan

1990
Effects of subacute toluene exposure on neuronal and glial marker proteins in rat brain.
    Toxicology, 1990, Apr-17, Volume: 61, Issue:2

    Topics: Animals; Biomarkers; Body Weight; Brain; Creatine Kinase; Immunoenzyme Techniques; Isoenzymes; Male;

1990
A comparative study of the effects of benzene, toluene, and xylenes on their in vitro metabolism and drug-metabolizing enzymes in rat liver.
    Toxicology and applied pharmacology, 1986, Volume: 82, Issue:2

    Topics: Animals; Benzene; Body Weight; Chromatography, Gas; Cytochrome P-450 Enzyme System; Enzyme Induction

1986
[Effects of dibenzyltoluene on fetal developments of rats].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1988, Issue:106

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Dose-Response Relationship, Drug;

1988
Increased water drinking following repeated exposures to toluene vapor in rats.
    Industrial health, 1988, Volume: 26, Issue:2

    Topics: Animals; Body Weight; Diuresis; Drinking Behavior; Male; Rats; Rats, Inbred Strains; Toluene; Water-

1988
Brain lipid changes in rats exposed to xylene and toluene.
    Toxicology, 1987, Volume: 45, Issue:2

    Topics: Animals; Atmosphere Exposure Chambers; Body Weight; Brain; Cholesterol; Liver; Male; Organ Size; Pho

1987
Subchronic oral toxicity of 4-chloro-alpha, alpha, alpha-trifluorotoluene in Sprague-Dawley rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1987, Volume: 25, Issue:10

    Topics: Administration, Oral; Animals; Body Weight; Dose-Response Relationship, Drug; Female; Kidney Disease

1987
Combined effects of n-hexane and toluene on norepinephrine and dopamine levels in rat brain tissues after long-term exposures.
    Bulletin of environmental contamination and toxicology, 1986, Volume: 36, Issue:4

    Topics: Animals; Body Weight; Brain Chemistry; Dopamine; Hexanes; Male; Norepinephrine; Rats; Rats, Inbred S

1986
Interactions between toluene and alcohol.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:3

    Topics: Alcohol Drinking; Animals; Blood Chemical Analysis; Body Weight; Choice Behavior; Conditioning, Oper

1985
Neonatal exposure to toluene: effects on the development of liver microsomal cytochrome P-450 and serum hormone levels in the rat.
    Toxicology, 1985, Volume: 37, Issue:1-2

    Topics: Androstenedione; Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Atmosphere Exposure Chamb

1985
Learning deficits in 4 weeks old offspring of the nursing mothers treated with the neuroleptic drug penfluridol.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Avoidance Learning; Body Weight; Breast Feeding; Female; Glu

1973
Regional changes in monoamine levels and in the rate of tyrosine and tryptophan hydroxylation in 4 week old offspring of nursing mothers treated with the neuroleptic drug penfluridol.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:4

    Topics: 5-Hydroxytryptophan; Age Factors; Animals; Animals, Newborn; Biogenic Amines; Body Weight; Brain; Br

1974
Synergistic toxicity and carcinogenicity of 'freons' and piperonyl butoxide.
    Nature, 1967, Apr-29, Volume: 214, Issue:5087

    Topics: Animals; Body Weight; Carcinogens; Carcinoma, Hepatocellular; Drug Synergism; Female; Halogens; Live

1967
[Influence of butyl-hydroxy-toluene (BHT) on the cytochrome oxidase activity in rat liver].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1969, Mar-17, Volume: 268, Issue:11

    Topics: Animals; Antioxidants; Body Weight; Diet; Electron Transport Complex IV; Female; Liver; Male; Organ

1969
Vascular damage and lipid peroxidation in choline-deficient rats.
    Experimental and molecular pathology, 1973, Volume: 18, Issue:3

    Topics: Animals; Anisoles; Aorta; Arteries; Barbiturates; Body Weight; Cholesterol, Dietary; Choline Deficie

1973
The effect of butylated hydroxytoluene, butylated hydroxyanisole and octyl gallate upon liver weight and biphenyl 4-hydroxylase activity in the rat.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:8

    Topics: Animals; Body Weight; Butyrates; Diet; Dietary Fats; Gallic Acid; Liver; Male; Microsomes; Mixed Fun

1966
Study of long-term percutaneous toxicity and carcinogenicity of hair dyes (oxidizing dyes) in rats.
    Food and cosmetics toxicology, 1973, Volume: 11, Issue:4

    Topics: Administration, Topical; Alanine Transaminase; Animals; Anisoles; Behavior, Animal; Blood Cell Count

1973
Effects of egg yolk and moctamide on serum lipids in man.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Amides; Anticholesteremic Agents; Appetite; Autoanalysis; Body Weight; Cholestero

1974
Long-term inhalation screening studies of benzene, toluene, o-xylene, and cumene on experimental animals.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:3

    Topics: Aerosols; Animals; Benzene; Blood Cells; Blood Chemical Analysis; Body Weight; Dogs; Female; Guinea

1970
Effect of antioxidants on life-span of C57BL mice.
    Journal of gerontology, 1971, Volume: 26, Issue:3

    Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Body Weight; Environment;

1971
Persistence of Phosvel in corn silage and effects of feeding dairy cows the treated silage.
    Journal of dairy science, 1971, Volume: 54, Issue:12

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cattle; Cholinesteras

1971
Effects of two synthetic antioxidants, vitamin E, and ascorbic acid on the choline-deficient rat.
    The Journal of nutrition, 1969, Volume: 97, Issue:2

    Topics: Animals; Antioxidants; Aorta; Ascorbic Acid; Body Weight; Cholesterol; Choline Deficiency; Coronary

1969