toluene 2,4-diisocyanate has been researched along with Inflammation in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (12.73) | 18.7374 |
| 1990's | 14 (25.45) | 18.2507 |
| 2000's | 14 (25.45) | 29.6817 |
| 2010's | 13 (23.64) | 24.3611 |
| 2020's | 7 (12.73) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, S; Dong, H; Huang, M; Lan, Z; Li, B; Liu, L; Peng, X; Wang, X; Yu, C; Yuan, Y; Zhao, H; Zhao, W | 1 |
| Cai, S; Chen, Y; Han, H; Huang, J; Lan, Z; Peng, X; Yang, S; Zhao, H; Zhao, W | 1 |
| Cai, S; Chen, X; Chen, Y; Gong, Z; Huang, J; Li, Y; Peng, X; Wang, Y; Yang, S; Yu, C; Zhao, H; Zhao, W | 1 |
| Cui, H; He, J; He, Y; Luo, G; Sun, E; Yang, F; Zhai, Z; Zhao, H; Zhao, W; Zhuang, J; Zhuang, L | 1 |
| Cai, S; Cheng, W; Cheng, Y; Cui, H; Dong, J; He, Y; Wang, L; Zhao, H; Zhao, W; Zhou, FH | 1 |
| Bo, C; Chen, Y; Jia, Q; Jiao, B; Peng, C; Sai, L; Shao, H; Yang, Y; Yu, G; Zhang, Y | 1 |
| Chang, P; Chen, S; Chen, X; Deng, Y; Li, J; Song, J; Tang, H; Xu, C; Yao, L | 1 |
| Ban, GY; Kim, SH; Park, HS; Pham, DL; Trinh, TH | 1 |
| Fukuyama, T; Ishimota, M; Makino, E; Tajiki-Nishino, R; Tajima, H; Watanabe, Y | 1 |
| Ban, GY; Choi, Y; Izuhara, K; Kim, SH; Lee, JH; Park, HS; Shin, YS; Trinh, HKT; Yang, EM; Ye, YM | 1 |
| Chen, R; Chen, S; Chen, X; Huang, P; Liang, Z; Tang, H; Tao, A; Wei, S; Yang, H; Yao, L; Zhang, Q | 1 |
| Patil, UK; Smita, J | 1 |
| Bernstein, DI; Boulet, LP; Cartier, A; Cruz, MJ; Fluharty, K; Gautrin, D; Johnson, VJ; Kashon, ML; Lummus, ZL; Luster, MI; Munoz, X; Quirce, S; Sastre, J; Tarlo, SM; Yucesoy, B | 1 |
| Cai, S; Dong, H; Li, W; Liu, L; Song, J; Tang, H; Tong, W; Yao, L; Zhao, H; Zou, F; Zou, M | 1 |
| Chen, X; Dai, Y; Geng, X; Jia, Q; Ju, R; Ma, Y; Meng, T; Meng, X; Miao, P; Niu, Y; Shao, H; Wang, C; Zheng, Y | 1 |
| Alpizar, YA; Boonen, B; Devos, FC; Hoet, PH; Hox, V; Liston, A; Maes, T; Nemery, B; Pollaris, L; Seys, S; Talavera, K; Vanoirbeek, JA | 1 |
| Bäumer, W; Crapo, JD; Daniele, MA; Fukuyama, T; Oberley, R; Stover, K; Young, AT | 1 |
| Jang, SH; Jang, YS; Jung, KS; Kim, JH; Kim, SH; Park, HS; Ye, YM | 1 |
| Jabłońska, E; Kur, B; Polakowska, E; Tarkowski, M | 1 |
| Hong, CS; Hur, GY; Jang, AS; Kim, CW; Kim, SH; Park, CS; Park, HS; Park, SM; Ye, YM | 1 |
| Bäumer, W; Jennings, G; Rundfeldt, C; Wlaź, P | 1 |
| Clynen, E; De Vooght, V; Haenen, S; Hoet, PH; Maes, E; Nemery, B; Schoofs, L; Vanoirbeek, JA | 1 |
| Jin, SM; Kim, HJ; Lee, KS; Lee, YC | 1 |
| Jin, SM; Kim, SS; Lee, KS; Lee, YC | 1 |
| Bloksma, N; Henricks, PA; Nijkamp, FP; Schijf, MA; Valstar, DL | 1 |
| Johnson, VJ; Luster, MI; Yucesoy, B | 1 |
| Choi, IW; Kim, SH; Lee, CM; Lee, HK; Moon, DO; Park, HJ; Park, YM; Roh, HJ | 1 |
| Ikeda, K; Shimizu, Y; Sugahara, S; Yamamoto, S | 1 |
| Jin, SM; Kim, SR; Lee, HK; Lee, KS; Lee, YC; Min, KH; Park, SJ | 1 |
| Aardal, NP; Aasen, TB; Bronstad, AM; Elsayed, S; Irgens, A; Sun, LZ; Van Do, T | 1 |
| Choe, YH; Hong, SJ; Kim, JS; Kim, SR; Lee, KS; Lee, KY; Lee, YC; Lee, YR; Min, KH; Park, SJ | 1 |
| Alenius, H; Laitinen, A; Luukkonen, R; Majuri, ML; Mäntylä, T; Meuronen, A; Nordman, H; Piirilä, PL; Wolff, HJ | 1 |
| Salvaggio, JE; Wilson, MR | 1 |
| Amitani, R; Kawai, M; Kuze, F; Niimi, A; Tanaka, K; Yamada, K | 2 |
| Chitano, P; Fabbri, LM; Karol, MH; Lapa e Silva, JR; Lucchini, RE; Maestrelli, P; Mapp, CE; Pretolani, M; Rado, V; Saetta, M | 1 |
| Ban, M; Bonnet, P; Gagnaire, F; Lemonnier, M; Micillino, JC | 1 |
| Billie, M; Castranova, V; Dedhia, HV; Frazer, D; Huffman, LJ; Judy, DJ; Shapiro, RE | 1 |
| Chitano, P; Fabbri, LM; Jovine, L; Lucchini, RE; Maestrelli, P; Mapp, CE; Miotto, D; Polak, J; Saetta, M; Springall, DR | 1 |
| Castranova, V; Dey, RD; Frazer, DG; Manley, LK | 1 |
| Kwak, YG; Lee, YC; Song, CH | 1 |
| De Marzo, N; Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, GF; Pivirotto, F; Saetta, M | 2 |
| Erjefält, I; Persson, CG | 1 |
| Fabbri, LM; Mapp, CE; Picotti, G; Saetta, M | 1 |
| Fabbri, LM; Mapp, CE; Picotti, G | 1 |
| Erjefält, I; Gustafsson, B; Luts, A; Persson, CG; Sundler, F | 1 |
| Fabbri, LM; Maestrelli, P; Mapp, CE; Saetta, M | 1 |
| Fabbri, LM; Mapp, C | 1 |
| Boschetto, P; Bruchi, O; Cappellazzo, G; Fabbri, LM; Mapp, CE; Milani, GF; Pivirotto, F; Zocca, E | 1 |
| Sheppard, D | 1 |
| Fabbri, LM | 1 |
| Distefano, S; Gordon, T; McDonald, DM; Scypinski, L; Sheppard, D | 1 |
| Gordon, T | 1 |
| Boschetto, P; Dal Vecchio, A; Fabbri, LM; Mapp, CE; Milani, G; Pivirotto, F; Plebani, M; Zocca, E | 1 |
5 review(s) available for toluene 2,4-diisocyanate and Inflammation
| Article | Year |
|---|---|
Pulmonary alterations associated with inhalation of occupational and environmental irritants.
Topics: Animals; Cell Count; Environmental Exposure; Guinea Pigs; Humans; Inflammation; Inhalation Exposure; Irritants; Lung; Male; Nasal Mucosa; Neurons, Afferent; Neuropeptides; Occupational Exposure; Rats; Rats, Sprague-Dawley; Respiration; Toluene 2,4-Diisocyanate | 2002 |
Late asthmatic reactions, airway inflammation and chronic asthma in TDI sensitized subjects.
Topics: Asthma; Chronic Disease; Humans; Inflammation; Occupational Diseases; Prognosis; Respiratory Hypersensitivity; Time Factors; Toluene 2,4-Diisocyanate | 1991 |
Bronchial hyperresponsiveness, airway inflammation and occupational asthma induced by toluene diisocyanate.
Topics: Animals; Asthma; Bronchi; Humans; Inflammation; Occupational Diseases; Prognosis; Toluene 2,4-Diisocyanate | 1991 |
Mechanisms of acute increases in airway responsiveness caused by environmental chemicals.
Topics: Air Pollutants; Animals; Humans; Inflammation; Ozone; Pulmonary Ventilation; Respiratory Physiological Phenomena; Toluene 2,4-Diisocyanate | 1988 |
Airway inflammation and asthma. Importance of arachidonate metabolites for airway hyperresponsiveness.
Topics: Acetylcholine; Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Humans; Inflammation; Ozone; Prednisone; Time Factors; Toluene 2,4-Diisocyanate | 1985 |
1 trial(s) available for toluene 2,4-diisocyanate and Inflammation
| Article | Year |
|---|---|
Prednisone inhibits late asthmatic reactions and airway inflammation induced by toluene diisocyanate in sensitized subjects.
Topics: Adult; Albumins; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Exudates and Transudates; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocytosis; Male; Middle Aged; Prednisone; Respiratory System; Therapeutic Irrigation; Toluene 2,4-Diisocyanate | 1987 |
49 other study(ies) available for toluene 2,4-diisocyanate and Inflammation
| Article | Year |
|---|---|
RAGE mediates airway inflammation via the HDAC1 pathway in a toluene diisocyanate-induced murine asthma model.
Topics: Animals; Asthma; Benzamides; Cell Line; Cytokines; Depsipeptides; Disease Models, Animal; Histone Deacetylase 1; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases; Receptor for Advanced Glycation End Products; Signal Transduction; Toluene 2,4-Diisocyanate | 2022 |
[Inhibition of TAK1 aggravates airway inflammation by increasing RIPK1 activity and promoting macrophage death in a mouse model of toluene diisocyanate-induced asthma].
Topics: Animals; Asthma; Inflammation; Macrophages; Mice; Receptor-Interacting Protein Serine-Threonine Kinases; Respiratory System; Toluene 2,4-Diisocyanate | 2022 |
Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma.
Topics: Animals; Asthma; Dexamethasone; Disease Models, Animal; Extracellular Traps; Humans; Inflammation; Interleukin-8; Mice; Steroids; Toluene 2,4-Diisocyanate | 2023 |
Bronchial epithelial pyroptosis promotes airway inflammation in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Asthma; Bronchi; Cell Line; Cytokines; Disease Models, Animal; Epithelial Cells; Humans; Inflammasomes; Inflammation; Male; Mice; Mice, Inbred BALB C; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 2020 |
The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model.
Topics: Airway Remodeling; Animals; Anti-Inflammatory Agents; Asthma; Cytokines; Dexamethasone; Disease Models, Animal; Heterocyclic Compounds, 3-Ring; Immunoglobulin E; Inflammation; Male; Mice; Mice, Inbred BALB C; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Toluene 2,4-Diisocyanate; Treatment Outcome | 2020 |
Toluene diisocyanate-induced inflammation and airway remodeling involves autophagy in human bronchial epithelial cells.
Topics: Airway Remodeling; Allergens; Autophagy; Bronchi; Cell Line; Cell Survival; Cytokines; Epithelial Cells; Humans; Inflammation; NF-E2-Related Factor 2; Reactive Oxygen Species; Serum Albumin, Human; Toluene 2,4-Diisocyanate | 2021 |
Distinct roles of PI3Kδ and PI3Kγ in a toluene diisocyanate-induced murine asthma model.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Class I Phosphatidylinositol 3-Kinases; Class Ib Phosphatidylinositol 3-Kinase; Disease Models, Animal; Eosinophils; Inflammation; Macrophages; Male; Mice; Mice, Inbred BALB C; Neutrophils; Toluene 2,4-Diisocyanate | 2021 |
Epithelial folliculin is involved in airway inflammation in workers exposed to toluene diisocyanate.
Topics: Adult; Biomarkers; Cell Line; Estrone; Female; Humans; Inflammation; Male; Middle Aged; Neutrophils; Occupational Exposure; Respiratory Function Tests; Respiratory Mucosa; Toluene 2,4-Diisocyanate | 2017 |
Oral Administration of Bisphenol A Directly Exacerbates Allergic Airway Inflammation but Not Allergic Skin Inflammation in Mice.
Topics: Administration, Oral; Animals; Benzhydryl Compounds; Cell Line; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Disease Progression; Environmental Pollutants; Epithelial Cells; Female; Humans; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Phenols; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 2018 |
Serum Periostin Levels: A Potential Serologic Marker for Toluene Diisocyanate-Induced Occupational Asthma.
Topics: Adult; Asthma; Asthma, Occupational; Biomarkers; Case-Control Studies; Cell Adhesion Molecules; Endothelial Cells; Female; Humans; Inflammation; Male; Neutrophils; Occupational Diseases; Reactive Oxygen Species; Toluene 2,4-Diisocyanate; Transforming Growth Factor beta1 | 2018 |
Transient Receptor Potential Ion Channels Mediate Adherens Junctions Dysfunction in a Toluene Diisocyanate-Induced Murine Asthma Model.
Topics: Acetanilides; Adherens Junctions; Animals; Asthma; beta Catenin; Bronchoalveolar Lavage Fluid; Cadherins; Cytokines; Epithelial Cells; Inflammation; Lung; Mice; Mice, Inbred C57BL; Phosphorylation; Piperidines; Purines; Quinolines; Toluene 2,4-Diisocyanate; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2019 |
Effect of Ipomea carnea Jacq. flowers on hematological changes in toluene diisocyanate-induced inflammation in Wistar rats.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Eosinophils; Female; Flowers; Hematology; Inflammation; Ipomoea; Leukocyte Count; Male; Molecular Structure; Neutrophils; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Stigmasterol; Toluene 2,4-Diisocyanate | 2014 |
Genetic variants in TNFα, TGFB1, PTGS1 and PTGS2 genes are associated with diisocyanate-induced asthma.
Topics: Adult; Asthma, Occupational; Case-Control Studies; Cyclooxygenase 1; Cyclooxygenase 2; DNA Mutational Analysis; Environmental Exposure; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Inflammation; Male; Polymorphism, Single Nucleotide; Toluene 2,4-Diisocyanate; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2016 |
1,25-Dihydroxyvitamin D3 prevents toluene diisocyanate-induced airway epithelial barrier disruption.
Topics: Animals; Asthma; Cadherins; Calcitriol; Cell Line; Cell Membrane Permeability; Electric Impedance; Eosinophils; Extracellular Signal-Regulated MAP Kinases; Humans; Immunoglobulin E; Inflammation; Interferon-gamma; Interleukin-4; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Occludin; Respiratory Mucosa; Tight Junctions; Toluene 2,4-Diisocyanate; Zonula Occludens-1 Protein | 2015 |
[Effect of occupational exposure to toluene diisocyanate on workers' health].
Topics: Case-Control Studies; Erythrocyte Count; Forced Expiratory Volume; Humans; Inflammation; L-Lactate Dehydrogenase; Leukocyte Count; Lung; Occupational Exposure; Pulmonary Ventilation; Succinate Dehydrogenase; Superoxide Dismutase; Toluene 2,4-Diisocyanate; Vital Capacity | 2016 |
Neuro-immune interactions in chemical-induced airway hyperreactivity.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Calcium; CHO Cells; Cricetulus; Inflammation; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Patch-Clamp Techniques; Sensory Receptor Cells; Toluene 2,4-Diisocyanate; TRPA1 Cation Channel; TRPV Cation Channels | 2016 |
Topically applied manganese-porphyrins BMX-001 and BMX-010 display a significant anti-inflammatory response in a mouse model of allergic dermatitis.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Cell Line; Dendritic Cells; Dermatitis, Allergic Contact; Disease Models, Animal; Ear; Female; Humans; Infant, Newborn; Inflammation; Interleukin-1beta; Interleukin-4; Keratinocytes; Metalloporphyrins; Mice; Mice, Inbred BALB C; p-Methoxy-N-methylphenethylamine; Pruritus; Skin; Skin Cream; Superoxide Dismutase; Toluene 2,4-Diisocyanate | 2016 |
Toluene diisocyanate exposure induces airway inflammation of bronchial epithelial cells via the activation of transient receptor potential melastatin 8.
Topics: Bronchi; Cell Line; Humans; Inflammation; Interleukins; Respiratory Mucosa; RNA, Messenger; Toluene 2,4-Diisocyanate; TRPM Cation Channels | 2017 |
Comparative studies of lymph node cell subpopulations and cytokine expression in murine model for testing the potentials of chemicals to induce respiratory sensitization.
Topics: Allergens; Animals; Bronchial Provocation Tests; Cytokines; Dinitrochlorobenzene; Disease Models, Animal; Inflammation; Interferon-gamma; Interleukin-4; Irritants; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Respiratory Hypersensitivity; RNA, Messenger; Toluene 2,4-Diisocyanate | 2008 |
Tissue transglutaminase can be involved in airway inflammation of toluene diisocyanate-induced occupational asthma.
Topics: Adult; Asthma; Case-Control Studies; Female; GTP-Binding Proteins; Humans; Immunoglobulin E; Immunoglobulin G; Inflammation; Male; Middle Aged; Occupational Diseases; Protein Glutamine gamma Glutamyltransferase 2; Reactive Oxygen Species; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate; Transglutaminases; Young Adult | 2009 |
The putative lipid raft modulator miltefosine displays immunomodulatory action in T-cell dependent dermal inflammation models.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Disease Models, Animal; Ear; Female; Hypersensitivity; Immunologic Factors; Inflammation; Interleukins; Membrane Microdomains; Mice; Phosphorylcholine; Pruritus; Skin; T-Lymphocytes; Toluene 2,4-Diisocyanate | 2010 |
Proteome analysis of multiple compartments in a mouse model of chemical-induced asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation; Mass Spectrometry; Methacholine Chloride; Mice; Neutrophils; Oxidative Stress; Proteome; Toluene 2,4-Diisocyanate | 2010 |
Matrix metalloproteinase inhibitor regulates inflammatory cell migration by reducing ICAM-1 and VCAM-1 expression in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Movement; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-4; Leukocytes; Lung; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; RNA, Messenger; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2003 |
Doxycycline reduces airway inflammation and hyperresponsiveness in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Anti-Bacterial Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Doxycycline; Female; Inflammation; Lung; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Ovalbumin; Protease Inhibitors; RNA, Messenger; Toluene 2,4-Diisocyanate | 2004 |
Glutathione-conjugated toluene diisocyanate causes airway inflammation in sensitised mice.
Topics: Airway Resistance; Animals; Bronchial Provocation Tests; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Inflammation; Lung; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 2004 |
Prevention of IL-1 signaling attenuates airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Antibody Formation; Antibody Specificity; Asthma; Disease Models, Animal; Female; Inflammation; Interleukin-1; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Interleukin-1; Respiratory Hypersensitivity; Signal Transduction; Toluene 2,4-Diisocyanate; Up-Regulation | 2005 |
Epigallocatechin-3-gallate protects toluene diisocyanate-induced airway inflammation in a murine model of asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Catechin; Disease Models, Animal; Gene Expression Regulation; Inflammation; Interleukin-5; Matrix Metalloproteinase 9; Mice; Reactive Oxygen Species; Respiratory System; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 2006 |
Pharmacological profile of a novel phosphodiesterase 7A and -4 dual inhibitor, YM-393059, on acute and chronic inflammation models.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acute Disease; Animals; Anti-Inflammatory Agents; Carrageenan; Chronic Disease; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 7; Cyclosporine; Dermatitis, Contact; Edema; Erythrocytes; Fumarates; Hypersensitivity, Delayed; Immunosuppressive Agents; Indoles; Inflammation; Male; Mice; Mice, Inbred BALB C; Peritonitis; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Sheep; Sulfonamides; Toluene 2,4-Diisocyanate; Zymosan | 2006 |
Modulation of airway remodeling and airway inflammation by peroxisome proliferator-activated receptor gamma in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Asthma; Cell Adhesion Molecules; Cytokines; Disease Models, Animal; Inflammation; Mice; NF-kappa B; PPAR gamma; Respiratory System; Th2 Cells; Toluene 2,4-Diisocyanate; Transforming Growth Factor beta1 | 2006 |
Airway inflammation and bronchial remodelling in toluene diisocyanate-exposed BALB/c mouse model.
Topics: Alum Compounds; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Inflammation; Interleukin-4; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Th2 Cells; Toluene 2,4-Diisocyanate | 2007 |
PTEN down-regulates IL-17 expression in a murine model of toluene diisocyanate-induced airway disease.
Topics: Adenoviridae; Animals; Asthma; Disease Models, Animal; Down-Regulation; Female; Inflammation; Inhalation Exposure; Interleukin-17; Mice; Mice, Inbred BALB C; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Sulfones; Toluene 2,4-Diisocyanate | 2007 |
Inflammation and functional outcome in diisocyanate-induced asthma after cessation of exposure.
Topics: Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoscopy; Female; Humans; Inflammation; Interleukin-4; Macrophages; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Respiratory Function Tests; Respiratory Mucosa; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 2008 |
Activation of the alternative pathway of complement: a mechanism in search of diseases.
Topics: Anaphylaxis; Asthma; Byssinosis; Complement Activation; Complement C1s; Complement C3b; Complement C3b Inactivator Proteins; Complement Pathway, Alternative; Humans; Inflammation; Toluene 2,4-Diisocyanate | 1980 |
[Airway inflammatory cell dynamics during late asthmatic reactions induced by toluene diisocyanate in guinea pigs. I. Bronchoalveolar lavage study].
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Guinea Pigs; Hypersensitivity, Delayed; Inflammation; Male; Respiratory System; Toluene 2,4-Diisocyanate | 1993 |
[Airway inflammatory cell dynamics during late asthmatic reactions induced by toluene diisocyanate in guinea pigs. II. Histological study].
Topics: Animals; Asthma; Bronchi; Eosinophils; Guinea Pigs; Hypersensitivity, Delayed; Inflammation; Male; Neutrophils; Toluene 2,4-Diisocyanate | 1993 |
Inflammatory events in the blood and airways of guinea pigs immunized to toluene diisocyanate.
Topics: Animals; Antibodies; Asthma; Blood Cell Count; Bronchi; Eosinophils; Guinea Pigs; Immunization; Immunoglobulin G; Immunohistochemistry; Inflammation; Lung; Male; Mast Cells; Toluene 2,4-Diisocyanate | 1996 |
Bronchial responsiveness and inflammation in guinea-pigs exposed to toluene diisocyanate: a study on single and repeated exposure.
Topics: Acetylcholine; Administration, Inhalation; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Female; Guinea Pigs; Inflammation; Neutrophils; Time Factors; Toluene 2,4-Diisocyanate | 1996 |
Inhalation of toluene diisocyanate is associated with increased production of nitric oxide by rat bronchoalveolar lavage cells.
Topics: Administration, Inhalation; Air; Animals; Arginine; Blotting, Northern; Bronchoalveolar Lavage Fluid; Cells, Cultured; Enzyme Induction; Inflammation; Luminescent Measurements; Macrophages, Alveolar; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Respiratory Function Tests; RNA, Messenger; Toluene 2,4-Diisocyanate; Zymosan | 1997 |
Immunization and challenge with toluene diisocyanate decrease tachykinin and calcitonin gene-related peptide immunoreactivity in guinea pig central airways.
Topics: Animals; Bronchial Provocation Tests; Calcitonin Gene-Related Peptide; Cell Count; Disease Models, Animal; Eosinophils; Guinea Pigs; Immunization; Immunoglobulin G; Immunohistochemistry; Inflammation; Male; Nerve Fibers; Respiratory System; Substance P; Tachykinins; Toluene 2,4-Diisocyanate | 1998 |
Contribution of vascular endothelial growth factor to airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma.
Topics: Administration, Inhalation; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Migration Inhibition; Cell Movement; Disease Models, Animal; Endothelial Growth Factors; Extravasation of Diagnostic and Therapeutic Materials; Female; Indoles; Inflammation; Leukocyte Count; Lymphokines; Mice; Mice, Inbred BALB C; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Toluene 2,4-Diisocyanate; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Airway mucosal inflammation in occupational asthma induced by toluene diisocyanate.
Topics: Adolescent; Adult; Asthma; Basement Membrane; Bronchi; Bronchoscopy; Eosinophils; Epithelium; Female; Humans; Inflammation; Male; Mast Cells; Middle Aged; Mucous Membrane; Occupational Diseases; Toluene 2,4-Diisocyanate | 1992 |
Effect of cessation of exposure to toluene diisocyanate (TDI) on bronchial mucosa of subjects with TDI-induced asthma.
Topics: Adult; Asthma; Basement Membrane; Biopsy; Bronchi; Bronchoscopy; Female; Humans; Inflammation; Male; Middle Aged; Mucous Membrane; Occupational Diseases; Toluene 2,4-Diisocyanate | 1992 |
Increased sensitivity to toluene diisocyanate (TDI) in airways previously exposed to low doses of TDI.
Topics: Administration, Cutaneous; Administration, Topical; Animals; Budesonide; Guinea Pigs; Inflammation; Intubation, Intratracheal; Male; Pregnenediones; Respiratory Hypersensitivity; Theophylline; Toluene 2,4-Diisocyanate; Xanthines | 1992 |
Late asthmatic reactions, airway inflammation and chronic asthma in toluene-diisocyanate-sensitized subjects.
Topics: Asthma; Bronchi; Eosinophils; Humans; Immunization; Inflammation; Lung; Occupational Diseases; Prognosis; Toluene 2,4-Diisocyanate | 1991 |
Toluene diisocyanate produces an increase in airway tone that outlasts the inflammatory exudation phase.
Topics: Airway Resistance; Animals; Carbachol; Exudates and Transudates; Guinea Pigs; Inflammation; Male; Mucous Membrane; Muscle, Smooth; Terbutaline; Theophylline; Toluene 2,4-Diisocyanate; Trachea | 1991 |
Airway inflammation during late asthmatic reactions induced by toluene diisocyanate.
Topics: Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Humans; Inflammation; Toluene 2,4-Diisocyanate | 1991 |
Importance of airway inflammation for late asthmatic reactions induced by toluene diisocyanate in sensitized subjects.
Topics: Adult; Asthma; Cyanates; Humans; Inflammation; Male; Methacholine Chloride; Methacholine Compounds; Respiratory System; Time Factors; Toluene 2,4-Diisocyanate | 1987 |
Airway hyperresponsiveness and inflammation induced by toluene diisocyanate in guinea pigs.
Topics: Acetylcholine; Animals; Cyanates; Eosinophils; Guinea Pigs; Inflammation; Male; Neutrophils; Ozone; Respiratory System; Smoking; Toluene 2,4-Diisocyanate; Trachea; Tracheitis | 1985 |
Purity of catalase preparations: contamination by endotoxin and its role in the inhibition of airway inflammation.
Topics: Animals; Catalase; Drug Contamination; Drug Synergism; Edema; Endotoxins; Guinea Pigs; Inflammation; Neutrophils; Toluene 2,4-Diisocyanate; Tracheal Diseases | 1986 |