toluene 2,4-diisocyanate has been researched along with Hypersensitivity in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (17.39) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukui, H; Kalubi, B; Kitamura, Y; Kuroda, W; Miyamoto, Y; Mizuguchi, H; Takeda, N | 1 |
| Dosso, M; Kouadio, K; Todoriki, H; Toure, AA; Zheng, KC | 1 |
| Adachi, T; Das, AK; Fukui, H; Kadota, T; Kitamura, Y; Kominami, T; Kosaka, T; Matsumoto, M; Miyagi, K; Mizuguchi, H; Orimoto, N; Sawada, A; Takeda, N; Tamada, M | 1 |
| Das, AK; Dev, S; Fukui, H; Kitamura, Y; Maeyama, K; Mizuguchi, H; Shahriar, M; Takeda, N | 1 |
| Das, AK; Dev, S; Fukui, H; Kitamura, Y; Kodama, M; Matsushita, C; Mizuguchi, H; Takeda, N; Umehara, H | 1 |
| Das, AK; Dev, S; Fukui, H; Hattori, M; Horinaga, S; Kato, S; Maeyama, K; Mizuguchi, H; Tamada, M; Umehara, H | 1 |
| Shusterman, D | 1 |
| Bäumer, W; Jennings, G; Rundfeldt, C; Wlaź, P | 1 |
| Aoyama, K | 1 |
| Chang, WF; Chiung, YM; Kao, YY; Liu, PS; Yao, CW | 1 |
| Baba, Y; Das, AK; Dev, S; Fukui, H; Mizuguchi, H | 1 |
| Fukui, H | 1 |
| Axmon, A; Broberg, K; Littorin, M; Rannug, A; Tinnerberg, H; Warholm, M | 1 |
| Pepys, J | 1 |
| Chen, BM; Huang, J; Matsushita, T; Wang, XP; Zhou, XJ | 1 |
| Okamoto, Y; Sawahata, T; Sugawara, Y; Tanaka, K | 1 |
| Manetz, TS; Meade, BJ | 1 |
| Chen, TH; Kishino, Y; Komatsu, T; Sakai, K; Takeshita, K; Yamamoto, S | 1 |
| He, B; Meade, BJ; Munson, AE | 1 |
| Alarie, YC; Ioset, HH; Karol, MH | 1 |
| Butcher, BT; Dharmarajan, V; Karr, RM; O'Neil, CE; Salvaggio, JE; Weill, H; Wilson, MR | 1 |
| Alarie, Y; Karol, MH; Riley, EJ; Sandberg, T | 1 |
| Abe, Y; Hong, SL; Irifune, M; Kalubi, B; Matsunaga, T; Ogino, S; Takeda, N; Tohyama, M; Yamano, M | 1 |
2 review(s) available for toluene 2,4-diisocyanate and Hypersensitivity
| Article | Year |
|---|---|
[Recent development in animal testing to predict the skin and respiratory sensitizing potential of chemicals].
Topics: Animal Experimentation; Animals; Bronchial Provocation Tests; Guinea Pigs; Humans; Hypersensitivity; Local Lymph Node Assay; Mice; Patch Tests; Predictive Value of Tests; Risk Assessment; Thymidine; Toluene 2,4-Diisocyanate | 2010 |
Occupational asthma: review of present clinical and immunologic status.
Topics: Bronchial Provocation Tests; Haptens; Humans; Hypersensitivity; Immunization; Molecular Weight; Occupational Diseases; Platinum; Radioallergosorbent Test; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate | 1980 |
21 other study(ies) available for toluene 2,4-diisocyanate and Hypersensitivity
| Article | Year |
|---|---|
Combination of leukotoriene receptor antagonist with antihistamine has an additive suppressive effect on the up-regulation of H1-receptor mRNA in the nasal mucosa of toluene 2,4-diisocyanate-sensitized rat.
Topics: Animals; Chlorpheniramine; Chromones; Drug Therapy, Combination; Histamine Antagonists; Hypersensitivity; Leukotriene Antagonists; Male; Nasal Mucosa; Rats; Receptors, Histamine H1; RNA, Messenger; Toluene 2,4-Diisocyanate | 2013 |
IL-4 and IL-5 secretions predominate in the airways of wistar rats exposed to toluene diisocyanate vapor.
Topics: Animals; Bronchoalveolar Lavage Fluid; Enzyme-Linked Immunosorbent Assay; Eosinophils; Female; Gases; Hypersensitivity; Interleukin-4; Interleukin-5; Lung; Rats; Rats, Wistar; Toluene 2,4-Diisocyanate | 2014 |
Suplatast tosilate alleviates nasal symptoms through the suppression of nuclear factor of activated T-cells-mediated IL-9 gene expression in toluene-2,4-diisocyanate-sensitized rats.
Topics: Animals; Anti-Allergic Agents; Arylsulfonates; Calcineurin; Cells, Cultured; Drug Therapy, Combination; Gene Expression; Histamine Antagonists; Hypersensitivity; Interleukin-9; Male; NFATC Transcription Factors; Nose Diseases; Rats; Receptors, Histamine H1; Signal Transduction; Sulfonium Compounds; Toluene 2,4-Diisocyanate | 2016 |
Antihistamines suppress upregulation of histidine decarboxylase gene expression with potencies different from their binding affinities for histamine H1 receptor in toluene 2,4-diisocyanate-sensitized rats.
Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Gene Expression; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histidine Decarboxylase; Humans; Hypersensitivity; Male; Molecular Targeted Therapy; Protein Binding; Rats; Receptors, Histamine H1; RNA, Messenger; Signal Transduction; Toluene 2,4-Diisocyanate; Up-Regulation | 2016 |
Sho-seiryu-to suppresses histamine signaling at the transcriptional level in TDI-sensitized nasal allergy model rats.
Topics: Animals; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Histamine; Histidine Decarboxylase; Hypersensitivity; Male; Medicine, Kampo; Nasal Mucosa; Rats; Rats, Inbred BN; Receptors, Histamine H1; RNA, Messenger; Signal Transduction; Toluene 2,4-Diisocyanate | 2009 |
Kujin suppresses histamine signaling at the transcriptional level in toluene 2,4-diisocyanate-sensitized rats.
Topics: Animals; Cytokines; Fabaceae; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine Release; Histidine Decarboxylase; Hypersensitivity; Male; Nasal Mucosa; Plant Roots; Pyrilamine; Rats; Rats, Inbred BN; Receptors, Histamine H1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Th2 Cells; Toluene 2,4-Diisocyanate; Transcription, Genetic | 2009 |
Neurogenic inflammation: additional points.
Topics: Air Pollutants; Air Pollution, Indoor; Humans; Hypersensitivity; Inhalation Exposure; Neurogenic Inflammation; Receptors, Neurokinin-1; Sensory Receptor Cells; Toluene 2,4-Diisocyanate | 1994 |
The putative lipid raft modulator miltefosine displays immunomodulatory action in T-cell dependent dermal inflammation models.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Disease Models, Animal; Ear; Female; Hypersensitivity; Immunologic Factors; Inflammation; Interleukins; Membrane Microdomains; Mice; Phosphorylcholine; Pruritus; Skin; T-Lymphocytes; Toluene 2,4-Diisocyanate | 2010 |
Toluene diisocyanate (TDI) induces calcium elevation and interleukine-4 (IL-4) release - early responses upon TDI stimulation.
Topics: Animals; Calcium; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Hypersensitivity; Interleukin-4; Jurkat Cells; RNA, Messenger; Toluene 2,4-Diisocyanate | 2010 |
Transcriptional microarray analysis reveals suppression of histamine signaling by Kujin alleviates allergic symptoms through down-regulation of FAT10 expression.
Topics: Animals; Disease Models, Animal; Down-Regulation; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity; Male; Microarray Analysis; Nasal Mucosa; Phytotherapy; Plant Extracts; Rats; Rats, Inbred Strains; Signal Transduction; Sophora; Toluene 2,4-Diisocyanate; Ubiquitins | 2011 |
Progress in allergy signal research on mast cells: up-regulation of histamine signal-related gene expression in allergy model rats.
Topics: Animals; Dexamethasone; Disease Models, Animal; Gene Expression Regulation; HeLa Cells; Histamine; Histidine Decarboxylase; Humans; Hypersensitivity; Male; Mast Cells; Nasal Mucosa; Rats; Rats, Inbred BN; Receptors, Histamine H1; Signal Transduction; Toluene 2,4-Diisocyanate; Up-Regulation | 2008 |
Influence of genetic factors on toluene diisocyanate-related symptoms: evidence from a cross-sectional study.
Topics: Adolescent; Adult; Air Pollutants, Occupational; Allergens; Biomarkers; Cross-Sectional Studies; Eye Diseases; Female; Genetic Predisposition to Disease; Genotype; Humans; Hypersensitivity; Male; Middle Aged; Occupational Exposure; Polymorphism, Single Nucleotide; Respiratory Tract Diseases; Sweden; Toluene 2,4-Diisocyanate | 2008 |
Dose-response relationships for chemical sensitization from TDI and DNCB.
Topics: Administration, Inhalation; Administration, Topical; Animals; Cytoplasmic Granules; Dinitrochlorobenzene; Guinea Pigs; Histamine Release; Hypersensitivity; Mast Cells; Mice; Mice, Inbred BALB C; Spectrometry, Fluorescence; Toluene 2,4-Diisocyanate | 1993 |
Skin reactivity in guinea pigs sensitized with 2,4-toluene diisocyanate.
Topics: Animals; Basophils; Guinea Pigs; Hypersensitivity; Immunization, Passive; Male; Mast Cells; Skin; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate | 1993 |
Development of a flow cytometry assay for the identification and differentiation of chemicals with the potential to elicit irritation, IgE-mediated, or T cell-mediated hypersensitivity responses.
Topics: Administration, Cutaneous; Animals; Dermatitis, Contact; Dinitrofluorobenzene; Dose-Response Relationship, Drug; Edema; Female; Flow Cytometry; Hypersensitivity; Immunoglobulin G; Irritants; Lymph Nodes; Mice; Phenotype; Sodium Dodecyl Sulfate; Specific Pathogen-Free Organisms; T-Lymphocytes; Toluene 2,4-Diisocyanate | 1999 |
Effect of amino acid mixtures on nasal allergic responses induced by toluene diisocyanate in mice.
Topics: Administration, Intranasal; Amino Acids; Animals; Dietary Proteins; Female; Hypersensitivity; Mice; Toluene 2,4-Diisocyanate | 2000 |
Analysis of gene expression induced by irritant and sensitizing chemicals using oligonucleotide arrays.
Topics: Animals; Fatty Acids; Female; Gene Expression; Gene Expression Profiling; Humans; Hypersensitivity; Immunization; Irritants; Mice; Mice, Inbred BALB C; Occupational Diseases; Oligonucleotide Array Sequence Analysis; Oxazolone; Reverse Transcriptase Polymerase Chain Reaction; Toluene 2,4-Diisocyanate | 2001 |
Tolyl-specific IgE antibodies in workders with hypersensitivity to toluene diisocyanate.
Topics: Antibodies; Antibody Specificity; Cyanates; Environmental Exposure; Haptens; Humans; Hypersensitivity; Immunoglobulin E; Occupational Diseases; Radioimmunoassay; Toluene 2,4-Diisocyanate | 1978 |
Inhalation challenge and pharmacologic studies of toluene diisocyanate (TDI)-sensitive workers.
Topics: Aerosols; Complement System Proteins; Cromolyn Sodium; Cyanates; Cyclic AMP; Environmental Exposure; Histamine; Humans; Hypersensitivity; Lymphocytes; Methacholine Compounds; Occupational Diseases; Toluene 2,4-Diisocyanate | 1979 |
Longitudinal study of tolyl-reactive IgE antibodies in workers hypersensitive to TDI.
Topics: Adult; Bronchi; Cyanates; Female; Humans; Hypersensitivity; Hypersensitivity, Immediate; Immunoglobulin E; Male; Middle Aged; Radioallergosorbent Test; Skin Tests; Toluene 2,4-Diisocyanate | 1979 |
Nasal mucosa sensitization with toluene diisocyanate (TDI) increases preprotachykinin A (PPTA) and preproCGRP mRNAs in guinea pig trigeminal ganglion neurons.
Topics: Animals; Autoradiography; Calcitonin Gene-Related Peptide; Gene Expression; Guinea Pigs; Hypersensitivity; Immunization; Nasal Mucosa; Neurons; Protein Precursors; Reference Values; RNA, Messenger; Sulfur Radioisotopes; Tachykinins; Toluene 2,4-Diisocyanate; Trigeminal Ganglion | 1992 |