Page last updated: 2024-08-21

toluene 2,4-diisocyanate and Diseases, Occupational

toluene 2,4-diisocyanate has been researched along with Diseases, Occupational in 228 studies

Research

Studies (228)

Timeframe	Studies, this research(%)	All Research%
pre-1990	122 (53.51)	18.7374
1990's	54 (23.68)	18.2507
2000's	39 (17.11)	29.6817
2010's	12 (5.26)	24.3611
2020's	1 (0.44)	2.80

Authors

Authors	Studies
Frigo, AC; Liviero, F; Maestrelli, P; Mason, P	1
Goodman, JE; Lynch, HN; Prueitt, RL; Shi, L; Zu, K	1
Ishihara, Y; Isse, T; Kakiuchi, N; Kawamoto, T; Koriyama, C; Ohta, M; Tanaka, M; Tanaka, R; Tsuchiya, T; Tsuji, M; Yamamoto, M; Yu, HS	1
Ban, GY; Choi, Y; Izuhara, K; Kim, SH; Lee, JH; Park, HS; Shin, YS; Trinh, HKT; Yang, EM; Ye, YM	1
Bernstein, DI; Boulet, LP; Cartier, A; Gautrin, D; Ho, SM; Lummus, ZL; Ouyang, B; Ying, J	1
Axmon, A; Broström, JM; Ghalali, A; Högberg, J; Jönsson, BA; Lindh, CH; Littorin, M; Stenius, U; Tinnerberg, H; Ye, ZW; Zheng, H	1
Bonczarowska, M; Brzeźnicki, S; Czerczak, S; Dudek, W; Nowakowska-Świrta, E; Pałczyński, C; Świerczyńska-Machura, D; Walusiak-Skorupa, J; Wesolowski, W; Wittczak, T	1
Daniels, RD; Fent, KW; Pinkerton, LE; Yiin, JH	1
Kim, SR; Lee, YC	1
Cho, BY; Cho, EY; Hong, CS; Kim, CW; Kim, SH; Lee, JE; Park, CS; Park, HS; Shin, ES; Yang, EM	1
Choi, JH; Hong, CS; Hur, GY; Jang, AS; Kim, CW; Kim, SH; Lee, HY; Lee, KW; Park, CS; Park, HS	1
Hong, CS; Hur, GY; Jang, AS; Kim, CW; Kim, SH; Park, CS; Park, HS; Park, SM; Ye, YM	1
del Pozo, V; Fernández-Nieto, M; Pérez-Camo, I; Sánchez, JJ; Sastre, B; Sastre, J	1
Choi, GS; Kim, HY; Kim, JE; Kim, JH; Park, HS; Ye, YM	1
Moscato, G; Pala, G; Pignatti, P	1
Choi, GS; Hur, GY; Kim, JH; Kim, SH; Nam, YH; Park, HS; Park, SM	1
Pałczyński, C; Swierczyńska-Machura, D	1
Nichols, L; Sorahan, T	1
Brown, WE; Burkert, AL	1
Conner, PR	1
Diller, WF	1
Ott, MG	1
Liss, GM; Tarlo, SM	2
Jung, JW; Kim, HA; Kim, SS; Kim, YK; Lee, SK; Nahm, DH; Park, HS	1
Cuesta, J; De Las Heras, M; Fernández-Nieto, M; Novalbos, A; Quirce, S; Sastre, J	1
Allport, DC; Bugler, J; Chamberlain, JD; Clark, RL; Paddle, GM	1
Bononi, I; Boschetto, P; Maestrelli, P; Mapp, CE; Milan, G; Padoan, M; Piola, C; Pozzato, V; Simoni, M; Zedda, L	1
Liu, Q; Wisnewski, AV	1
BOFFARDI, G; JAMES, KE; LUNDY, W; SANDS, FW; WALSH, WS	1
GOWER, ND; JENNINGS, GH	1
SILVER, HM	1
MAXON, FC	1
KESSLER, RC	1
RUTGERS, VH	1
Barton, SJ; Beghé, B; Holgate, ST; Holloway, JW; Howell, WM; Mapp, CE; Moss, CT; Padoan, M	1
Jin, SM; Lee, H; Lee, KS; Lee, YC	1
Johnson, VJ; Luster, MI; Matheson, JM	1
Bousová, K; Krcmová, I	1
Bonauto, DK; Curwick, CC; Lofgren, DJ; Sumner, AD; Whittaker, SG	1
Hong, CS; Kim, CW; Kim, SH; Lee, KW; Nahm, DH; Oh, HB; Park, HS; Shin, ES	1
Baruffini, A; Bernabeo, F; Cerri, S; Mangili, A; Pisati, G	1
Hong, CS; Kang, YM; Kim, CW; Kim, HM; Kim, HR; Kim, SH; Nahm, DH; Park, CS; Park, HS; Ye, YM	1
Fujimura, M; Furusho, S; Kasahara, K; Kita, T; Myou, S; Nakao, S; Sato, S; Takehara, K; Yasui, M	1
Bernstein, DI; Graham, C; Lummus, Z; Ott, MG; Woolhiser, M	1
Hong, CS; Kim, CW; Kim, HR; Nahm, DH; Park, CS; Park, HS; Suh, CH; Ye, YM	1
Fluharty, K; Johnson, VJ; Luster, MI; Reynolds, JS; Richardson, D; Wang, W; Yucesoy, B	1
Ayres, JG; Dick, FD; Shakeri, MS	1
Alenius, H; Laitinen, A; Luukkonen, R; Majuri, ML; Mäntylä, T; Meuronen, A; Nordman, H; Piirilä, PL; Wolff, HJ	1
Hargreave, FE; Pugsley, SO; Ramsdale, EH	1
Filieri, M; Gerosa, F; Paggiaro, P; Pezzini, A; Riviera, A; Spiazzi, A; Toma, G; Tridente, G	1
Baschieri, L; Ferrante, B; Loi, AM; Paggiaro, PL; Pardi, F; Roselli, MG; Rossi, O	1
Candura, F; Moscato, G	1
Fujimura, N; Izumi, T; Kino, T; Kitaichi, M; Nagai, S; Ogawa, S; Oshima, S; Sato, K	1
Omae, K	1
Biscaldi, G; Candura, F; Gherson, G; Moscato, G	1
Biscaldi, G; Candura, F; Cottica, D; Moscato, G	1
Morris, MJ; Sugden, E; White, WG; Zapata, E	1
Bernstein, IL; Blanchard, J; Brooks, SM; Gallagher, J; Smith, AB	1
Hopkins, J	2
Oleru, UG	1
Pepys, J	1
Check, WA	1
Butcher, BT	4
Kielar, R; Luckenbach, M	1
Baur, X; Diller, W; Dorsch, W; Fruhmann, G; Römmelt, H; Roth, P	1
Buckingham, JA; Cromwell, O; Danks, JM; Davies, RJ; Newman-Taylor, AJ	1
Sepúlveda, R	1
Weill, H	1
Reed, CE	1
Bernstein, IL; Brooks, SM; Gallagher, JS; Tse, CS	1
Karol, MH	1
Dorofeeva, ED; Kryzhanovskaia, NA; Mel'nikova, ND; Penkovich, AA; Sharonova, ZV	1
Woolrich, PF	1
Bachmann, K; Forney, RB; Shapiro, R	1
Hurst, DJ	1
Bernstein, IL	1
Butcher, BT; Dharmarajan, V; Diem, JE; Glindmeyer, HW; Hendrick, DJ; Jones, RN; Salvaggio, JE; Weill, H	1
Bernstein, IL; Chen, SE	1
Bernstein, IL; Chen, SE; Splansky, GL; Vinegar, A	1
Main, DM; Musk, AW; Pagnotto, LD; Wegman, DH	1
Baur, X	1
Burge, PS	1
Butcher, BT; O'Neil, CE; Reed, MA; Salvaggio, JE	1
Baschieri, L; Cantalupi, R; Filieri, M; Loi, AM; Paggiaro, PL; Parlanti, A; Roselli, MG; Toma, G	1
Wang, SR; Wang, SS	1
Audunsson, G; Belin, L; Mathiasson, L; Wass, U	1
Eisen, EA; Greaves, IA; Robins, J	1
Daimon, N; Kido, T; Shimizu, T; Teranishi, H; Yamada, Y	1
Kawai, M; Maekawa, N; Tanaka, K	1
Blainey, D; Davies, R	1
Booth, N; Broder, I; Corey, PN; Guirguis, S; Holness, DL; Mozzon, D; Nazar, MA	1
Bernstein, DI; Herd, ZL	1
di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, G; Occari, P; Pivirotto, F; Saetta, M; Turato, G	1
Fujimoto, H; Funasako, M; Higashimoto, Y; Nakamura, Y; Ohata, M; Sumda, T; Uetani, K	1
Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, G; Pivirotto, F; Saetta, M; Turato, G	1
D'Elios, MM; De Carli, M; Del Prete, GF; Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Romagnani, S; Saetta, M	1
Ciaccia, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Saetta, M	1
Campbell, TP; Fabbri, L; Karol, MH; Maestrelli, P; Mapp, CE; Saetta, M; Tollerud, DJ	1
Bacci, E; Bancalari, L; Carrara, M; Dente, FL; Di Franco, A; Giannini, D; Giuntini, C; Paggiaro, PL; Vagaggini, B	1
Calcagni, PG; Di Stefano, A; Fabbri, LM; Hosselet, JJ; Maestrelli, P; Mapp, CE; Saetta, M; Santonastaso, A	1
Bando, T; Fujimura, M; Hirose, J; Matsuda, T; Noda, Y; Ohta, G; Shibata, K	1
Hagmar, L; Mikoczy, Z; Strömberg, U; Welinder, H	1
Baruffini, A; Pisati, G; Zedda, S	1
Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, G; Pivirotto, F; Saetta, M	1
Baur, X; Marczynski, B; Marek, W; Potthast, J	2
Korn, EL; Roe, DJ	1
Hagmar, L; Mikoczy, Z; Welinder, H	1
Boscaro, M; De Marzo, N; Fabbri, LM; Maestrelli, P; Mapp, CE; Saetta, M	1
Biscaldi, G; Corsico, A; Dellabianca, A; Gherson, G; Moscato, G; Vinci, G	1
Balboni, A; Baricordi, OR; Ciaccia, A; Fabbri, LM; Gandini, E; Mapp, CE	1
Baur, X; Marcynski, B; Marek, W; Potthast, JJ	1
Choi, J; Kim, H; Kim, YD	1
Nahm, DH; Park, HS	1
Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, GF; Occari, P; Papiris, SA; Saetta, M; Turato, G	1
Fernando, R; Siribaddana, SH; Wijesundera, A	1
Kim, YT; Lee, M; Park, H; Son, M; Youn, JK	1
Alam, R; Bernstein, DI; Bernstein, JA; Lummus, ZL	1
Desrosiers, M; Ghezzo, H; Leblanc, C; Malo, JL; Nguyen, B	1
Frossard, N; Kopferschmitt-Kubler, MC; Pauli, G; Rohde, G	1
Jung, K; Kang, K; Kim, H; Nahm, D; Park, H	1
Klees, JE; Ott, MG; Poche, SL	1
Balboni, A; Baricordi, OR; Beghè, B; Fabbri, LM; Jovine, L; Mapp, CE; Padoan, M; Zamorani, G	1
Choi, IS; Jang, AS; Koh, YI; Lee, KJ; Moon, JD	1
Fischer, A; Frossard, N; Lugnier, A; Pons, F	1
Bugler, J; Clark, RL; Meredith, SK	1
De Zotti, R; Muran, A; Zambon, F	1
Beasley, BW; Frazier, LM; Mohyuddin, AA; Sharma, GK	1
He, B; Meade, BJ; Munson, AE	1
Bodner, KM; Burns, CJ; Randolph, NM; Salazar, EJ	1
Ariizumi, M; Morioka, T; Nong, DX; Todoriki, H; Zheng, KC	1
Boschetto, P; De Marzo, N; Fryer, AA; Hemmingsen, A; Mapp, CE; Padoan, M; Pozzato, V; Spiteri, MA; Strange, RC	1
Butcher, BT; Garg, O; O'Neil, CE; Salvaggio, JE; Weill, H	1
Butcher, BT; Dharmarajan, V; Diem, JE; Glindmeyer, HW; Jones, RN; O'Neil, CE; Salvaggio, JE; Weill, H	1
Burge, PS; Harries, MG; O'Brien, I; Taylor, AJ	1
Adams, WG	1
Higgins, RL; Porter, CV; Scheel, LD	1
Butcher, B; Neilson, A; Salvaggio, J; Weill, H; Ziskind, M	1
Peters, JM; Wegman, DH	1
Aresini, G; Cirla, A; Sala, C; Zedda, S	1
Hutchcroft, BJ; Pepys, J	1
Dahl, R; Zetterström, O	1
Axford, AT; Jones, AP; Le Quesne, PM; McKerrow, CB	2
Alanko, K; Häkkinen, I; Vaaranen, IH	1
Kryshanovskaia, NA; Sharonova, ZV	1
Butcher, BT; Davies, RJ; Salvaggio, JE	1
Fine, LJ; Pagnotto, L; Peters, JM; Wegman, DH	1
Perrault, JL; Renzi, G	1
Abbritti, G; Curradi, F; Siracusa, A	1
Reinhardt, CF	1
Alarie, YC; Ioset, HH; Karol, MH	1
Okada, A; Yamada, Y	1
Saita, G	1
Cirla, AM; Sala, C; Zedda, S	1
Braman, SS; Teplitz, C	1
Brethauer, R; Chester, EH; Fleming, GM; Gerblich, AA; Horowitz, J; Martinez-Catinchi, FL; McDonald, EW; Schwartz, HJ	1
Butcher, BT; Dharmarajan, V; Karr, RM; O'Neil, CE; Salvaggio, JE; Weill, H; Wilson, MR	1
Burge, PS; Harries, MG; O'Brien, IM	1
Lubach, D	2
Salvaggio, JE	1
Chester, EH; Fleming, GM; Gerblich, AA; Horowitz, J; Schwartz, HJ	1
Baur, X; Fruhmann, G; Römmelt, H	1
Alarie, Y; Karol, MH; Riley, EJ	1
Fink, JN; Schlueter, DP	1
De Marzo, N; Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, GF; Pivirotto, F; Saetta, M	2
Cartier, A; Grammer, LC; Lesage, J; Malo, JL; Perrault, G; Vandenplas, O	1
Kim, JW; Kim, SK; Park, HS; Park, JN	1
Schenker, M	1
Foster, TA; Glindmeyer, HW; Hughes, JM; Jones, RN; O'Neil, CE; Rando, RJ; Weill, H	1
Baur, X; Fruhmann, G; Vogelmeier, C	1
Bossi, MC; Candura, SM; Dellabianca, A; Moscato, G; Vinci, G	1
Fabbri, LM; Mapp, CE; Picotti, G; Saetta, M	1
Idezuka, J; Ikarashi, H; Maruyama, M; Nozawa, S; Sasagawa, M; Suzuki, E	1
Fabbri, LM; Mapp, CE; Picotti, G	1
Aoyama, K; Chen, BM; Huang, J; Matsushita, T; Ueda, A; Wang, XP	1
Liu, JY	1
Fabbri, LM; Finotto, S; Maestrelli, P; Mapp, CE; Rado, V	1
Fabbri, LM; Mapp, C	1
Baik, JH; Cho, DI; Cho, YS; Kim, JW; Park, HS; Park, JN; Rhu, NS	1
Banks, DE; Barkman, HW; Rando, RJ	1
Eberle, ME; Harris, KE; Nugent, KM; Patterson, R	1
Fischbein, A; Luo, JC; Nelsen, KG	1
Cartier, A; Grammer, LC; Harris, KE; Malo, JL; Patterson, R	1
Bacci, E; Bernard, P; Dente, FL; Giuntini, C; Marchetti, G; Menconi, GF; Paggiaro, P; Paoletti, P; Talini, D	1
Lee, HS; Phoon, WH; Poh, SC; Wang, YT	1
Hasegawa, S; Noguchi, K; Ohtsuka, M; Suko, M; Uchida, Y; Yoshizawa, Y	1
Belin, L; Wass, U	1
Broughton, A; Gard, Z; Madison, R; Thrasher, JD	1
Dahl, R; Rasmussen, K	1
Bodner, KM; Bond, GG; Emmitte, JA; Flores, GH; Olsen, GW; Saunders, JH; Shellenberger, R	1
Grammer, L	1
Duan, YY	1
Arakawa, M; Kioi, S; Nozawa, S; Sasagawa, M; Sato, T; Suzuki, E	1
Bacci, E; Dente, FL; Fabbri, LM; Giuntini, C; Paggiaro, P; Pulerá, N; Rossi, O; Talini, D	1
Huang, PH; Lin, JM; Su, SY; Wang, JD; Wu, MC	1
Boulet, LP	1
Cirla, AM; Innocenti, A; Mariano, A; Pisati, G	1
Banks, DE; Rando, RJ	1
Fiorini, R; Governa, M; Valentino, M	1
Gee, JB; Morgan, WK	1
Baschieri, L; Lastrucci, L; Paggiaro, PL; Pardi, F; Pezzini, A; Rossi, O	1
Fink, JN; Levy, MB	1
Karol, MH; Magreni, C; Stadler, J	1
Kay, S	1
Burge, PS; Dally, MB; Newman Taylor, AJ; Pickering, CA; Venables, KM	1
Purnell, CJ; Walker, RF	1
Dzhogan, IM	1
Boschetto, P; Dal Vecchio, L; De Marzo, N; Fabbri, LM; Mapp, CE	1
Bernstein, IL; Brooks, SM; McKay, RT; Moller, DR	1
Bernstein, IL; Brooks, SM; Cassedy, K; Kopp, S; McKay, RT; Moller, DR	1
Ito, T; Kudo, T; Miki, T; Shima, S; Tachikawa, S; Yoshida, T	1
Rosenberg, C; Savolainen, H	2
Banks, DE; Butcher, BT; Salvaggio, JE	1
Broseghini, C; Di Giacomo, GR; Fabbri, LM; Mapp, CE; Omini, C	1
Ermakova, GA; Kryzhanovskaia, NA; Liuro, SD; Sharonova, ZV; Volkova, ID	1
Dolovich, J; Grammer, LC; Hargreave, FE; Harris, KE; Patterson, R	1

Reviews

21 review(s) available for toluene 2,4-diisocyanate and Diseases, Occupational

Article	Year
Dermal exposure to toluene diisocyanate and respiratory cancer risk. Environment international, 2017, Volume: 109 Topics: Administration, Cutaneous; Air Pollutants; Animals; Humans; Inhalation Exposure; Lung Neoplasms; Occupational Diseases; Occupational Exposure; Risk; Toluene 2,4-Diisocyanate	2017
PTEN as a unique promising therapeutic target for occupational asthma. Immunopharmacology and immunotoxicology, 2008, Volume: 30, Issue:4 Topics: Animals; Anti-Asthmatic Agents; Asthma; Drug Delivery Systems; Humans; Occupational Diseases; PTEN Phosphohydrolase; Signal Transduction; Toluene 2,4-Diisocyanate	2008
[Pathogenetic and clinical aspects of diisocyanate asthma]. Medycyna pracy, 2012, Volume: 63, Issue:1 Topics: Air Pollutants, Occupational; Animals; Asthma; Bronchial Hyperreactivity; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Models, Animal; Humans; Immunoglobulin E; Mice; Occupational Diseases; Occupational Exposure; T-Lymphocytes; Toluene 2,4-Diisocyanate	2012
Biomarkers of toluene diisocyanate exposure. Applied occupational and environmental hygiene, 2002, Volume: 17, Issue:12 Topics: Air Pollutants, Occupational; Asthma; Biomarkers; Environmental Monitoring; Humans; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate	2002
Experience with early detection of toluene diisocyanate-associated occupational asthma. Applied occupational and environmental hygiene, 2002, Volume: 17, Issue:12 Topics: Air Pollutants, Occupational; Asthma; Environmental Monitoring; Humans; Occupational Diseases; Occupational Exposure; Occupational Health; Surveys and Questionnaires; Toluene 2,4-Diisocyanate	2002
Frequency and trends of occupational asthma due to toluene diisocyanate: a critical review. Applied occupational and environmental hygiene, 2002, Volume: 17, Issue:12 Topics: Air Pollutants, Occupational; Asthma; Chemical Industry; Cross-Sectional Studies; Global Health; Humans; Incidence; Longitudinal Studies; Occupational Diseases; Prevalence; Toluene 2,4-Diisocyanate	2002
Occupational asthma, lung function decrement, and toluene diisocyanate (TDI) exposure: a critical review of exposure-response relationships. Applied occupational and environmental hygiene, 2002, Volume: 17, Issue:12 Topics: Air Pollutants, Occupational; Asthma; Chemical Industry; Cross-Sectional Studies; Dose-Response Relationship, Drug; Europe; Humans; Longitudinal Studies; Occupational Diseases; Occupational Exposure; Outcome Assessment, Health Care; Respiratory Function Tests; Toluene 2,4-Diisocyanate; United States	2002
Diisocyanate-induced asthma: diagnosis, prognosis, and effects of medical surveillance measures. Applied occupational and environmental hygiene, 2002, Volume: 17, Issue:12 Topics: Air Pollutants, Occupational; Asthma; Diagnosis, Differential; Environmental Monitoring; Epidemiological Monitoring; Humans; Occupational Diseases; Ontario; Population Surveillance; Prognosis; Toluene 2,4-Diisocyanate	2002
Recent developments in diisocyanate asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:5 Suppl 2 Topics: Asthma; Cyanates; Epithelial Cells; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Isocyanates; Lung; Occupational Diseases; Occupational Exposure; Skin; Toluene 2,4-Diisocyanate	2003
Which agents cause reactive airways dysfunction syndrome (RADS)? A systematic review. Occupational medicine (Oxford, England), 2008, Volume: 58, Issue:3 Topics: Acetic Acid; Adult; Air Pollutants, Occupational; Chlorine; Environmental Exposure; Female; Humans; Male; Middle Aged; Nitrogen Oxides; Occupational Diseases; Occupational Exposure; Paint; Respiratory Hypersensitivity; Sulfur Dioxide; Toluene 2,4-Diisocyanate	2008
Occupational asthma: review of present clinical and immunologic status. The Journal of allergy and clinical immunology, 1980, Volume: 66, Issue:3 Topics: Bronchial Provocation Tests; Haptens; Humans; Hypersensitivity; Immunization; Molecular Weight; Occupational Diseases; Platinum; Radioallergosorbent Test; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate	1980
Toxicology, industrial hygiene and medical control of TDI, MDI and PMPPI. American Industrial Hygiene Association journal, 1982, Volume: 43, Issue:2 Topics: Animals; Chemical Phenomena; Chemistry; Cyanates; Humans; Isocyanates; Maximum Allowable Concentration; Occupational Diseases; Polymers; Toluene 2,4-Diisocyanate	1982
Isocyanate-induced pulmonary diseases: a current perspective. The Journal of allergy and clinical immunology, 1982, Volume: 70, Issue:1 Topics: Animals; Asthma; Cyanates; Humans; Lung Diseases; Occupational Diseases; Occupational Health Services; Toluene 2,4-Diisocyanate	1982
[The problem of isocyanates in industry. From pathology to control of the risk]. La Medicina del lavoro, 1978, Volume: 69 Suppl 3 Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Bronchitis; Cough; Cyanates; Humans; Industry; Lung Diseases; Occupational Diseases; Polyurethanes; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate	1978
Late asthmatic reactions, airway inflammation and chronic asthma in TDI sensitized subjects. The European respiratory journal. Supplement, 1991, Volume: 13 Topics: Asthma; Chronic Disease; Humans; Inflammation; Occupational Diseases; Prognosis; Respiratory Hypersensitivity; Time Factors; Toluene 2,4-Diisocyanate	1991
Bronchial hyperresponsiveness, airway inflammation and occupational asthma induced by toluene diisocyanate. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1991, Volume: 21 Suppl 1 Topics: Animals; Asthma; Bronchi; Humans; Inflammation; Occupational Diseases; Prognosis; Toluene 2,4-Diisocyanate	1991
[A case of hypersensitivity pneumonitis due to isocyanate (TDI)]. Nihon Kyobu Shikkan Gakkai zasshi, 1989, Volume: 27, Issue:11 Topics: Alveolitis, Extrinsic Allergic; Cyanates; Humans; Infusions, Intravenous; Isocyanates; Male; Methylprednisolone; Middle Aged; Occupational Diseases; Skin Tests; Toluene 2,4-Diisocyanate	1989
Hypersensitivity pneumonitis. Annals of allergy, 1985, Volume: 54, Issue:3 Topics: Alveolitis, Extrinsic Allergic; Bronchi; Drug Hypersensitivity; Humans; Occupational Diseases; Phthalic Anhydrides; Pulmonary Alveoli; Therapeutic Irrigation; Toluene 2,4-Diisocyanate	1985
Immunotoxicologic evaluation of the respiratory system: animal models for immediate- and delayed-onset pulmonary hypersensitivity. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:3 Topics: Animals; Bronchi; Disease Models, Animal; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Lung; Lung Diseases; Occupational Diseases; Skin Tests; Subtilisins; Time Factors; Toluene 2,4-Diisocyanate	1985
Methods for the determination of atmospheric organic isocyanates. A review. The Analyst, 1985, Volume: 110, Issue:8 Topics: Air Pollutants; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Colorimetry; Cyanates; Humans; Isocyanates; Occupational Diseases; Spectrophotometry, Infrared; Toluene 2,4-Diisocyanate	1985
Isocyanate-induced respiratory disease. Annals of allergy, 1986, Volume: 57, Issue:6 Topics: Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Occupational Diseases; Respiratory Hypersensitivity; Respiratory System; Toluene 2,4-Diisocyanate	1986

Trials

2 trial(s) available for toluene 2,4-diisocyanate and Diseases, Occupational

Article	Year
Protective effect of nifedipine upon specific bronchial responses to isocyanates. Giornale italiano di medicina del lavoro, 1983, Volume: 5, Issue:6 Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; Constriction, Pathologic; Cyanates; Humans; Male; Nifedipine; Occupational Diseases; Random Allocation; Toluene 2,4-Diisocyanate	1983
Effects of inhaled beclomethasone on airway responsiveness in occupational asthma. Placebo-controlled study of subjects sensitized to toluene diisocyanate. The American review of respiratory disease, 1993, Volume: 148, Issue:2 Topics: Adolescent; Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Placebos; Toluene 2,4-Diisocyanate	1993

Article

Year

Protective effect of nifedipine upon specific bronchial responses to isocyanates.

Giornale italiano di medicina del lavoro, 1983, Volume: 5, Issue:6

Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; Constriction, Pathologic; Cyanates; Humans; Male; Nifedipine; Occupational Diseases; Random Allocation; Toluene 2,4-Diisocyanate

1983

Effects of inhaled beclomethasone on airway responsiveness in occupational asthma. Placebo-controlled study of subjects sensitized to toluene diisocyanate.

The American review of respiratory disease, 1993, Volume: 148, Issue:2

Topics: Adolescent; Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Placebos; Toluene 2,4-Diisocyanate

1993

Other Studies

205 other study(ies) available for toluene 2,4-diisocyanate and Diseases, Occupational

Article	Year
Long-Term Follow-Up of Cluster-Based Diisocyanate Asthma Phenotypes. The journal of allergy and clinical immunology. In practice, 2021, Volume: 9, Issue:9 Topics: Asthma, Occupational; Follow-Up Studies; Humans; Occupational Diseases; Occupational Exposure; Phenotype; Toluene 2,4-Diisocyanate	2021
Evaluation of chemical-specific IgG antibodies in male workers from a urethane foam factory. Environmental health and preventive medicine, 2018, Jun-19, Volume: 23, Issue:1 Topics: Adult; Air Pollutants, Occupational; Environmental Monitoring; Humans; Immunoglobulin G; Japan; Male; Manufacturing and Industrial Facilities; Middle Aged; Occupational Diseases; Occupational Exposure; Phthalic Anhydrides; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate; Workforce	2018
Serum Periostin Levels: A Potential Serologic Marker for Toluene Diisocyanate-Induced Occupational Asthma. Yonsei medical journal, 2018, Volume: 59, Issue:10 Topics: Adult; Asthma; Asthma, Occupational; Biomarkers; Case-Control Studies; Cell Adhesion Molecules; Endothelial Cells; Female; Humans; Inflammation; Male; Neutrophils; Occupational Diseases; Reactive Oxygen Species; Toluene 2,4-Diisocyanate; Transforming Growth Factor beta1	2018
Interferon-γ promoter is hypermethylated in blood DNA from workers with confirmed diisocyanate asthma. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 133, Issue:2 Topics: Adult; Asthma; DNA; DNA Methylation; Epigenesis, Genetic; Female; Humans; Interferon-gamma; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Occupational Exposure; Promoter Regions, Genetic; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Young Adult	2013
Toluene diisocyanate: Induction of the autotaxin-lysophosphatidic acid axis and its association with airways symptoms. Toxicology and applied pharmacology, 2015, Sep-15, Volume: 287, Issue:3 Topics: Adult; Biomarkers; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Induction; Epithelial Cells; Female; Humans; Lung; Lung Diseases; Lysophospholipids; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Phosphoric Diester Hydrolases; Receptors, Purinergic P2X4; Receptors, Purinergic P2X7; Risk Assessment; RNA Interference; Signal Transduction; Sweden; Time Factors; Toluene 2,4-Diisocyanate; Transfection; Up-Regulation; Young Adult	2015
Occupational exposure to diisocyanates in polyurethane foam factory workers. International journal of occupational medicine and environmental health, 2015, Volume: 28, Issue:6 Topics: Adult; Air Pollutants, Occupational; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate; Workplace; Young Adult	2015
Mortality among workers exposed to toluene diisocyanate in the US polyurethane foam industry: Update and exposure-response analyses. American journal of industrial medicine, 2016, Volume: 59, Issue:8 Topics: Adult; Aged; Chemical Industry; Female; Follow-Up Studies; Humans; Life Tables; Lung Neoplasms; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Polyurethanes; Time Factors; Toluene 2,4-Diisocyanate; United States	2016
Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2009, Volume: 39, Issue:2 Topics: Adult; alpha Catenin; Asthma; B-Lymphocytes; Bronchial Provocation Tests; Cell Line, Transformed; Female; Gene Expression; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Humans; Immunoglobulin E; Immunoglobulin G; Keratin-19; Male; Middle Aged; Occupational Diseases; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide; Risk Factors; Toluene 2,4-Diisocyanate	2009
The HLA DRB11501-DQB10602-DPB10501 haplotype is a risk factor for toluene diisocyanate-induced occupational asthma. International archives of allergy and immunology, 2009, Volume: 150, Issue:2* Topics: Adult; Asthma; Female; Forced Expiratory Volume; Gene Frequency; Haplotypes; HLA-DP Antigens; HLA-DP beta-Chains; HLA-DQ Antigens; HLA-DQ beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Immunoglobulin E; Korea; Male; Membrane Glycoproteins; Middle Aged; Occupational Diseases; Risk Factors; Toluene 2,4-Diisocyanate	2009
Tissue transglutaminase can be involved in airway inflammation of toluene diisocyanate-induced occupational asthma. Journal of clinical immunology, 2009, Volume: 29, Issue:6 Topics: Adult; Asthma; Case-Control Studies; Female; GTP-Binding Proteins; Humans; Immunoglobulin E; Immunoglobulin G; Inflammation; Male; Middle Aged; Occupational Diseases; Protein Glutamine gamma Glutamyltransferase 2; Reactive Oxygen Species; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate; Transglutaminases; Young Adult	2009
Serum ferritin and transferrin levels are not serologic markers of toluene diisocyanate-induced occupational asthma. The Journal of allergy and clinical immunology, 2010, Volume: 125, Issue:3 Topics: Adult; Area Under Curve; Asthma; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Ferritins; Humans; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate; Transferrin	2010
Serum cytokines markers in toluene diisocyanate-induced asthma. Respiratory medicine, 2011, Volume: 105, Issue:7 Topics: Adult; Asthma; Biomarkers; Chemical Industry; Early Diagnosis; Female; Humans; Male; Matrix Metalloproteinase 9; Occupational Diseases; Occupational Exposure; Tissue Inhibitor of Metalloproteinase-1; Toluene 2,4-Diisocyanate; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A	2011
Occupational exposure to toluene diisocyanate and neutrophilic bronchitis without asthma. Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:6 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchitis; Chronic Disease; Cough; Female; Humans; Lymphocyte Count; Neutrophils; Occupational Diseases; Occupational Exposure; Spirometry; Sputum; Toluene 2,4-Diisocyanate	2011
Role of vitamin D-binding protein in isocyanate-induced occupational asthma. Experimental & molecular medicine, 2012, May-31, Volume: 44, Issue:5 Topics: Adult; Animals; Asthma; Cell Line; Epithelial Cells; Female; Gene Expression; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Rats; Toluene 2,4-Diisocyanate; Vitamin D-Binding Protein	2012
Mortality and cancer morbidity of production workers in the UK flexible polyurethane foam industry: updated findings, 1958-98. Occupational and environmental medicine, 2002, Volume: 59, Issue:11 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cause of Death; Chemical Industry; Cohort Studies; England; Female; Humans; Lung Neoplasms; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Polyurethanes; Respiratory Tract Diseases; Sex Characteristics; Toluene 2,4-Diisocyanate; Wales	2002
Metalloproteinase-9 is increased after toluene diisocyanate exposure in the induced sputum from patients with toluene diisocyanate-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2003, Volume: 33, Issue:1 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Case-Control Studies; Female; Gelatinases; Humans; Irritants; Lung; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methacholine Chloride; Middle Aged; Occupational Diseases; Sputum; Tissue Inhibitor of Metalloproteinase-1; Toluene 2,4-Diisocyanate	2003
Need for monitoring nonspecific bronchial hyperresponsiveness before and after isocyanate inhalation challenge. Chest, 2003, Volume: 123, Issue:4 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cyanates; False Negative Reactions; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Middle Aged; Monitoring, Physiologic; Occupational Diseases; Prospective Studies; Toluene 2,4-Diisocyanate	2003
A 17-year epidemiological study on changes in lung function in toluene diisocyanate foam workers. International archives of occupational and environmental health, 2003, Volume: 76, Issue:4 Topics: Adult; Age Factors; Construction Materials; Environmental Pollutants; Female; Humans; Longitudinal Studies; Lung Diseases; Male; Middle Aged; Occupational Diseases; Polyurethanes; Respiratory Function Tests; Smoking; Toluene 2,4-Diisocyanate; United Kingdom	2003
Long-term follow-up of toluene diisocyanate-induced asthma. The European respiratory journal, 2003, Volume: 21, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Follow-Up Studies; Humans; Logistic Models; Longitudinal Studies; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Occupational Exposure; Prognosis; Respiratory Function Tests; Toluene 2,4-Diisocyanate	2003
Toluene diisocyanate; engineering and medical control of exposures in polyurethane foam manufacturing. American Industrial Hygiene Association quarterly, 1957, Volume: 18, Issue:4 Topics: Cyanates; Engineering; Humans; Occupational Diseases; Polyurethanes; Toluene; Toluene 2,4-Diisocyanate	1957
Thrombocytopenic purpura in toluene di-isocyanate workers. Lancet (London, England), 1963, Feb-23, Volume: 1, Issue:7278 Topics: Cyanates; Humans; Occupational Diseases; Purpura, Thrombocytopenic; Toluene; Toluene 2,4-Diisocyanate	1963
TOLUENE DIISOCYANATE ASTHMA. REVIEW AND CASE REPORT WITH RESPONSE TO STEROIDS. Archives of internal medicine, 1963, Volume: 112 Topics: Asthma; Bronchial Spasm; Cyanates; Humans; Occupational Diseases; Respiratory Function Tests; Steroids; Toluene; Toluene 2,4-Diisocyanate; Toxicology	1963
RESPIRATORY IRRITATION FROM TOLUENE DIISOCYANATE. Archives of environmental health, 1964, Volume: 8 Topics: Cyanates; Humans; Occupational Diseases; Paint; Respiratory Function Tests; Respiratory Tract Diseases; Toluene; Toluene 2,4-Diisocyanate; Toxicology	1964
Pulmonary sensitization to toluene diisocyanate. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1960, Volume: 2 Topics: Cyanides; Humans; Nervous System Physiological Phenomena; Occupational Diseases; Toluene; Toluene 2,4-Diisocyanate	1960
[Observations on workers exposed to 2-4-toluene-diisocyanate (Desmodur T)]. Nederlands tijdschrift voor geneeskunde, 1962, Aug-25, Volume: 106 Topics: Cyanates; Humans; Lung Abscess; Occupational Diseases; Toluene; Toluene 2,4-Diisocyanate	1962
Lack of association of HLA class I genes and TNF alpha-308 polymorphism in toluene diisocyanate-induced asthma. Allergy, 2004, Volume: 59, Issue:1 Topics: Adult; Asthma; Case-Control Studies; Female; Genetic Predisposition to Disease; Histocompatibility Antigens Class I; Humans; Male; Middle Aged; Occupational Diseases; Polymorphism, Genetic; Probability; Prognosis; Reference Values; Risk Assessment; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha	2004
Imbalance between matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in toluene diisocyanate-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:2 Topics: Animals; Asthma; Blotting, Western; Bronchi; Bronchoalveolar Lavage Fluid; Female; Immunoblotting; Immunohistochemistry; Lung; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Models, Animal; Occupational Diseases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Solvents; Tissue Inhibitor of Metalloproteinase-1; Toluene 2,4-Diisocyanate	2004
Immune mediators in a murine model for occupational asthma: studies with toluene diisocyanate. Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 84, Issue:1 Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Enzyme-Linked Immunosorbent Assay; Eosinophils; Immunoglobulin E; Mice; Mice, Inbred C57BL; Mice, Knockout; Occupational Diseases; Peroxidases; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Th2 Cells; Toluene 2,4-Diisocyanate	2005
[Diisocyanate exposure as a cause of occupational asthma]. Acta medica (Hradec Kralove). Supplementum, 2004, Volume: 47, Issue:1 Topics: Adult; Asthma; Cyanates; Humans; Middle Aged; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate	2004
Work-related asthma in the spray-on truck bed lining industry. Journal of occupational and environmental medicine, 2005, Volume: 47, Issue:5 Topics: Adolescent; Adult; Asthma; Automobiles; Humans; Incidence; Male; Occupational Diseases; Occupational Exposure; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Washington; Workers' Compensation	2005
HLA DRB115-DPB105 haplotype: a susceptible gene marker for isocyanate-induced occupational asthma? Allergy, 2006, Volume: 61, Issue:7 Topics: Adult; Asthma; Biomarkers; Bronchial Provocation Tests; Bronchoconstrictor Agents; Case-Control Studies; Female; Haplotypes; HLA-DP Antigens; HLA-DP beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Korea; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Occupational Exposure; Skin Tests; Toluene 2,4-Diisocyanate	2006
Rechallenging subjects with occupational asthma due to toluene diisocyanate (TDI), after long-term removal from exposure. International archives of occupational and environmental health, 2007, Volume: 80, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Follow-Up Studies; Forced Expiratory Volume; Humans; Occupational Diseases; Occupational Exposure; Recovery of Function; Toluene 2,4-Diisocyanate	2007
Relationship between neurokinin 2 receptor gene polymorphisms and serum vascular endothelial growth factor levels in patients with toluene diisocyanate-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:9 Topics: Adult; Asthma; Female; Forced Expiratory Volume; Gene Frequency; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Immunoglobulin E; Male; Middle Aged; Occupational Diseases; Polymorphism, Single Nucleotide; Receptors, Neurokinin-2; Toluene 2,4-Diisocyanate; Vascular Endothelial Growth Factor A	2006
Role of intercellular adhesion molecule-1 in a murine model of toluene diisocyanate-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:10 Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Chemokine CXCL2; Chemokines; Immunoglobulin E; Immunoglobulin G; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-4; Interleukin-5; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha	2006
Evaluation of antibody binding to diisocyanate protein conjugates in a general population. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:3 Topics: Adolescent; Adult; Antibody Specificity; Cyanates; Environmental Exposure; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Prevalence; Toluene 2,4-Diisocyanate	2006
Cytokeratin autoantibodies: useful serologic markers for toluene diisocyanate-induced asthma. Yonsei medical journal, 2006, Dec-31, Volume: 47, Issue:6 Topics: Adult; Asthma; Autoantibodies; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoblotting; Keratin-18; Keratin-19; Keratin-8; Keratins; Male; Middle Aged; Occupational Diseases; Sensitivity and Specificity; Toluene 2,4-Diisocyanate	2006
Inhalation of toluene diisocyanate vapor induces allergic rhinitis in mice. Journal of immunology (Baltimore, Md. : 1950), 2007, Aug-01, Volume: 179, Issue:3 Topics: Administration, Inhalation; Aerosols; Animals; Antibody Specificity; Cytokines; Disease Models, Animal; Female; Immunoglobulin E; Immunoglobulin G; Mice; Mice, Inbred C57BL; Nasal Mucosa; Occupational Diseases; Random Allocation; Rhinitis, Allergic, Perennial; Th1 Cells; Th2 Cells; Toluene 2,4-Diisocyanate	2007
Inflammation and functional outcome in diisocyanate-induced asthma after cessation of exposure. Allergy, 2008, Volume: 63, Issue:5 Topics: Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoscopy; Female; Humans; Inflammation; Interleukin-4; Macrophages; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Respiratory Function Tests; Respiratory Mucosa; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha	2008
Occupational asthma without bronchial hyperresponsiveness. The American review of respiratory disease, 1984, Volume: 130, Issue:3 Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Peak Expiratory Flow Rate; Pulmonary Ventilation; Toluene 2,4-Diisocyanate	1984
Specific IgE antibodies in twenty-eight workers with diisocyanate-induced bronchial asthma. Clinical allergy, 1984, Volume: 14, Issue:5 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Toluene 2,4-Diisocyanate	1984
Follow-up study of patients with respiratory disease due to toluene diisocyanate (TDI). Clinical allergy, 1984, Volume: 14, Issue:5 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Respiratory Function Tests; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate	1984
Do amines induce occupational asthma in workers manufacturing polyurethane foams? British journal of industrial medicine, 1984, Volume: 41, Issue:4 Topics: Amines; Asthma; Chemical Industry; Humans; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Phenylenediamines; Polyurethanes; Toluene 2,4-Diisocyanate	1984
[Hypersensitivity pneumonitis in a polyurethane paint sprayer]. Nihon Kyobu Shikkan Gakkai zasshi, 1984, Volume: 22, Issue:6 Topics: Alveolitis, Extrinsic Allergic; Cyanates; Female; Humans; Lung; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1984
Two-year observation of pulmonary function in workers exposed to low concentrations of toluene diisocyanate. International archives of occupational and environmental health, 1984, Volume: 55, Issue:1 Topics: Adult; Cross-Sectional Studies; Cyanates; Follow-Up Studies; Humans; Lung; Male; Occupational Diseases; Respiratory Function Tests; Time Factors; Toluene 2,4-Diisocyanate	1984
Specific bronchial provocation tests in occupational asthma and methods of stimulation: case report. Giornale italiano di medicina del lavoro, 1983, Volume: 5, Issue:6 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Occupational Diseases; Paint; Respiratory Function Tests; Toluene 2,4-Diisocyanate	1983
Isocyanate-induced asthma in a car factory. Lancet (London, England), 1980, Apr-05, Volume: 1, Issue:8171 Topics: Asthma; Automobiles; Cyanates; Female; Humans; Immunoglobulin E; Occupational Diseases; Occupations; Respiratory Function Tests; Toluene 2,4-Diisocyanate	1980
Absence of airway hyperreactivity to methacholine in a worker sensitized to toluene diisocyanate (TDI). Journal of occupational medicine. : official publication of the Industrial Medical Association, 1980, Volume: 22, Issue:5 Topics: Adult; Airway Obstruction; Asthma; Bronchi; Cyanates; Dose-Response Relationship, Drug; Female; Humans; Methacholine Compounds; Occupational Diseases; Toluene 2,4-Diisocyanate	1980
Differences of opinion over TDI. Food and cosmetics toxicology, 1980, Volume: 18, Issue:2 Topics: Cyanates; Forced Expiratory Volume; Humans; Lung Diseases; Occupational Diseases; Toluene 2,4-Diisocyanate	1980
Respiratory function study of Nigerian workers in a TDI-based foam plant. American Industrial Hygiene Association journal, 1980, Volume: 41, Issue:8 Topics: Adult; Cyanates; Humans; Lung Diseases; Male; Nigeria; Occupational Diseases; Respiratory Function Tests; Smoking; Time Factors; Toluene 2,4-Diisocyanate	1980
Work-related asthma comes out of hiding. JAMA, 1980, Oct-10, Volume: 244, Issue:15 Topics: Allergens; Asthma; Cyanates; Molecular Weight; Occupational Diseases; Phthalic Anhydrides; Radioallergosorbent Test; Toluene 2,4-Diisocyanate	1980
Approaches to the understanding of mechanisms in occupational asthma. European journal of respiratory diseases. Supplement, 1980, Volume: 107 Topics: Allergens; Asthma; Humans; Lymphocytes; Occupational Diseases; Receptors, Adrenergic, beta; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate	1980
Toxic corneal epithelial edema from exposure to high atmospheric concentration of toluene diisocyanates. American journal of ophthalmology, 1980, Volume: 90, Issue:5 Topics: Adult; Conjunctival Diseases; Cornea; Corneal Diseases; Cyanates; Edema; Epithelium; Female; Humans; Male; Middle Aged; Occupational Diseases; Polyurethanes; Temperature; Time Factors; Toluene 2,4-Diisocyanate; Ventilation; Visual Acuity	1980
[Clinical symptoms and results of RAST and inhalation provocation tests]. Zentralblatt fur Arbeitsmedizin, Arbeitsschutz, Prophylaxe und Ergonomie, 1980, Volume: 30, Issue:4 Topics: Adult; Cyanates; Humans; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Radioimmunoassay; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate	1980
Toluene-diisocyanate induced asthma: evaluation of antibodies in the serum of affected workers against a tolyl mono-isocyanate protein conjugate. Clinical allergy, 1981, Volume: 11, Issue:2 Topics: Antibody Formation; Antibody Specificity; Asthma; Cyanates; Humans; Immunoglobulin E; Isocyanates; Occupational Diseases; Radioimmunoassay; Serum Albumin; Toluene 2,4-Diisocyanate	1981
[Occupational asthma (author's transl)]. Revista medica de Chile, 1980, Volume: 108, Issue:2 Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Occupational Diseases; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate	1980
Occupational lung diseases. State of the art. Chest, 1981, Volume: 80, Issue:1 Suppl Topics: Asbestosis; Byssinosis; Dust; Edible Grain; Gases; Humans; Lung Diseases; Occupational Diseases; Silicosis; Toluene 2,4-Diisocyanate	1981
Occupational asthma: a challenge in patient management and community care. Postgraduate medicine, 1981, Volume: 70, Issue:2 Topics: Asthma; Environmental Exposure; Humans; Immunization; Immunoglobulin E; Occupational Diseases; Occupational Medicine; Skin Tests; Toluene 2,4-Diisocyanate; United States	1981
Diverse profiles of immunoreactivity in toluene diisocyanate (TDI) asthma. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1981, Volume: 23, Issue:9 Topics: Adult; Antigen-Antibody Reactions; Asthma; Cell Migration Inhibition; Cyanates; Female; Humans; Immunity, Cellular; Lymphokines; Male; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Skin Tests; Toluene 2,4-Diisocyanate	1981
Survey of industrial workers for antibodies to toluene diisocyanate. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1981, Volume: 23, Issue:11 Topics: Antibody Formation; Cyanates; Drug Hypersensitivity; Humans; Immunoglobulin E; Occupational Diseases; Respiratory Distress Syndrome; Toluene 2,4-Diisocyanate	1981
[Cardiovascular system changes in workers in toluene diisocyanate manufacture]. Gigiena truda i professional'nye zabolevaniia, 1982, Issue:1 Topics: Adult; Cardiovascular System; Conjunctiva; Cyanates; Electrocardiography; Female; Humans; Male; Microcirculation; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1982
Warfarin binding to plasma of workers exposed to toluene diisocyanate. International journal of clinical pharmacology, therapy, and toxicology, 1982, Volume: 20, Issue:2 Topics: Adult; Blood Proteins; Chemical Industry; Cyanates; Humans; Occupational Diseases; Protein Binding; Rubber; Toluene 2,4-Diisocyanate; Warfarin	1982
Occupational asthma. The Journal of laboratory and clinical medicine, 1982, Volume: 99, Issue:5 Topics: Animals; Asthma; Bronchi; Cyanates; Dogs; Humans; Isocyanates; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate	1982
Five-year longitudinal study of workers employed in a new toluene diisocyanate manufacturing plant. The American review of respiratory disease, 1982, Volume: 126, Issue:3 Topics: Adult; Chemical Industry; Cyanates; Forced Expiratory Volume; Humans; Longitudinal Studies; Louisiana; Lung Diseases; Lung Volume Measurements; Male; Maximum Allowable Concentration; Occupational Diseases; Risk; Smoking; Spirometry; Toluene 2,4-Diisocyanate	1982
The guinea pig model of diisocyanate sensitization. I. Immunologic studies. The Journal of allergy and clinical immunology, 1982, Volume: 70, Issue:5 Topics: Animals; Asthma; Cross Reactions; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Humans; Immunization; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Passive Cutaneous Anaphylaxis; Serum Albumin; Toluene 2,4-Diisocyanate; Transferrin	1982
The guinea pig model of diisocyanate sensitization. II. Physiologic studies. The Journal of allergy and clinical immunology, 1982, Volume: 70, Issue:5 Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Immune Sera; Immunoglobulin E; Isocyanates; Occupational Diseases; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Transferrin	1982
Occupational asthma. The West Virginia medical journal, 1982, Volume: 78, Issue:6 Topics: Asthma; Cyanates; Humans; Male; Middle Aged; Occupational Diseases; Pneumoconiosis; Toluene 2,4-Diisocyanate	1982
Accelerated loss of FEV- in polyurethane production workers: a four-year prospective study. American journal of industrial medicine, 1982, Volume: 3, Issue:2 Topics: Cyanates; Dose-Response Relationship, Drug; Forced Expiratory Volume; Humans; Occupational Diseases; Prospective Studies; Regression Analysis; Smoking; Toluene 2,4-Diisocyanate	1982
Immunologic cross-reactivity between different albumin-bound isocyanates. The Journal of allergy and clinical immunology, 1983, Volume: 71, Issue:2 Topics: Adult; Aerosols; Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate	1983
Isocyanate induced asthma. European journal of respiratory diseases. Supplement, 1982, Volume: 123 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Forced Expiratory Volume; Humans; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate	1982
Mechanisms of isocyanate induced asthma. European journal of respiratory diseases. Supplement, 1982, Volume: 123 Topics: Asthma; Cyanates; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Immunoglobulin E; Lymphocytes; Occupational Diseases; Radioimmunoassay; Skin Tests; Toluene 2,4-Diisocyanate	1982
Non-specific bronchial hyper-reactivity in workers exposed to toluene di-isocyanate, diphenyl methane di-isocyanate and colophony. European journal of respiratory diseases. Supplement, 1982, Volume: 123 Topics: Asthma; Bronchi; Cyanates; Electronics; Environmental Exposure; Histamine; Humans; Isocyanates; Occupational Diseases; Resins, Plant; Toluene 2,4-Diisocyanate	1982
Radioallergosorbent testing with p-tolyl monoisocyanate in toluene diisocyanate workers. Clinical allergy, 1983, Volume: 13, Issue:1 Topics: Asthma; Cyanates; Dermatitis, Atopic; Drug Hypersensitivity; False Positive Reactions; Humans; Immunoglobulin E; Isocyanates; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate	1983
Absence of IgG antibodies to TDI-HSA in a radioimmunological study. Clinical allergy, 1983, Volume: 13, Issue:1 Topics: Animals; Asthma; Cyanates; Humans; Immunoglobulin G; Occupational Diseases; Rabbits; Radioimmunoassay; Respiratory Hypersensitivity; Serum Albumin; Toluene 2,4-Diisocyanate	1983
[Asthma induced by diphenylmethane diisocyanate]. Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology, 1983, Volume: 16, Issue:1 Topics: Adult; Asthma; Chemical Phenomena; Chemistry; Cyanates; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Risk; Toluene 2,4-Diisocyanate	1983
Amines: possible causative agents in the development of bronchial hyperreactivity in workers manufacturing polyurethanes from isocyanates. British journal of industrial medicine, 1983, Volume: 40, Issue:3 Topics: Adult; Aged; Amines; Bronchial Diseases; Chemical Industry; Forced Expiratory Volume; Humans; Maximal Expiratory Flow Rate; Methacholine Compounds; Middle Aged; Morpholines; Occupational Diseases; Piperazines; Polyurethanes; Skin Tests; Toluene 2,4-Diisocyanate	1983
Five-year longitudinal study of workers employed in a new toluene diisocyanate manufacturing plant. The American review of respiratory disease, 1983, Volume: 128, Issue:2 Topics: Cyanates; Humans; Longitudinal Studies; Maximum Allowable Concentration; Occupational Diseases; Toluene 2,4-Diisocyanate; United States	1983
[Toluene diisocyanate asthma. 1. Clinico-immunological evaluation]. Arerugi = [Allergy], 1983, Volume: 32, Issue:2 Topics: Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Immunoglobulin E; Male; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate	1983
Experimental model of asthma by toluene diisocyanate (TDI). Bulletin of the Chest Disease Research Institute, Kyoto University, 1983, Volume: 16, Issue:1-2 Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Lung; Male; Occupational Diseases; Toluene 2,4-Diisocyanate	1983
Anaphylactic reactions to industrial toxins. Developments in toxicology and environmental science, 1983, Volume: 11 Topics: Air Pollutants, Occupational; Anaphylaxis; Asthma; Dust; Edible Grain; Female; Humans; Male; Mites; Occupational Diseases; Potassium; Potassium Compounds; Skin Tests; Sulfates; Toluene 2,4-Diisocyanate	1983
Respiratory variables and exposure-effect relationships in isocyanate-exposed workers. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1984, Volume: 26, Issue:6 Topics: Adult; Air Pollutants, Occupational; Cough; Cyanates; Dyspnea; Female; Humans; Male; Middle Aged; Occupational Diseases; Respiratory Function Tests; Time Factors; Toluene 2,4-Diisocyanate	1984
Antigen-specific stimulation of histamine releasing factors in diisocyanate-induced occupational asthma. American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:4 Topics: Allergens; Antibody Specificity; Asthma; Biomarkers; Biomarkers, Tumor; Cells, Cultured; Dose-Response Relationship, Immunologic; Epitopes; Female; Histamine Release; Humans; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Occupational Diseases; Statistics, Nonparametric; Toluene 2,4-Diisocyanate; Tumor Protein, Translationally-Controlled 1	1994
Cytokines in the airway mucosa of subjects with asthma induced by toluene diisocyanate. American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:3 Pt 1 Topics: Adult; Asthma; Biopsy; Bronchi; Cell Adhesion; Cell Adhesion Molecules; Cytokines; E-Selectin; Female; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Leukocytes; Lymphocyte Activation; Male; Mast Cells; Occupational Diseases; Receptors, Interleukin-2; Receptors, Very Late Antigen; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha	1995
[A case of chronic hypersensitivity pneumonitis due to long term exposure to toluene diisocyanate]. Nihon Kyobu Shikkan Gakkai zasshi, 1995, Volume: 33, Issue:4 Topics: Alveolitis, Extrinsic Allergic; Chronic Disease; Humans; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate	1995
Airway wall remodeling after cessation of exposure to isocyanates in sensitized asthmatic subjects. American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:2 Pt 1 Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Time Factors; Toluene 2,4-Diisocyanate	1995
CD8 T-cell clones producing interleukin-5 and interferon-gamma in bronchial mucosa of patients with asthma induced by toluene diisocyanate. Scandinavian journal of work, environment & health, 1994, Volume: 20, Issue:5 Topics: Adult; Asthma; Biopsy; Bronchi; Bronchial Provocation Tests; Case-Control Studies; CD8-Positive T-Lymphocytes; Cells, Cultured; Clone Cells; Humans; Immunophenotyping; Interferon-gamma; Interleukin-5; Lymphocyte Activation; Male; Middle Aged; Mucous Membrane; Occupational Diseases; Toluene 2,4-Diisocyanate	1994
Low molecular weight pollutants and asthma: pathogenetic mechanisms and genetic factors. The European respiratory journal, 1994, Volume: 7, Issue:9 Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; HLA-DQ Antigens; HLA-DQ beta-Chains; Humans; Immunity, Cellular; Molecular Weight; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate	1994
Predictive value of airways hyperresponsiveness and circulating IgE for identifying types of responses to toluene diisocyanate inhalation challenge. American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:3 Pt 1 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chi-Square Distribution; Female; Forced Expiratory Volume; Humans; Immunoglobulin E; Immunoglobulin G; Male; Methacholine Chloride; Occupational Diseases; Predictive Value of Tests; Reproducibility of Results; Skin Tests; Toluene 2,4-Diisocyanate	1994
Bronchial hyperresponsiveness and toluene diisocyanate. Long-term change in sensitized asthmatic subjects. Chest, 1993, Volume: 103, Issue:4 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate	1993
Toluene diisocyanate induced asthma: outcome according to persistence or cessation of exposure. British journal of industrial medicine, 1993, Volume: 50, Issue:11 Topics: Asthma; Follow-Up Studies; Humans; Occupational Diseases; Toluene 2,4-Diisocyanate	1993
Sputum eosinophilia after asthmatic responses induced by isocyanates in sensitized subjects. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1994, Volume: 24, Issue:1 Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Eosinophilia; Female; Humans; Isocyanates; Leukocyte Count; Male; Occupational Diseases; Sputum; Toluene 2,4-Diisocyanate	1994
[A case of hypersensitivity pneumonitis induced by toluene diisocyanate presenting with transient bronchoconstriction]. Nihon Kyobu Shikkan Gakkai zasshi, 1993, Volume: 31, Issue:10 Topics: Alveolitis, Extrinsic Allergic; Asthma; Bronchoconstriction; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1993
Incidence of cancer and exposure to toluene diisocyanate and methylene diphenyldiisocyanate: a cohort based case-referent study in the polyurethane foam manufacturing industry. British journal of industrial medicine, 1993, Volume: 50, Issue:11 Topics: Case-Control Studies; Cohort Studies; Humans; Incidence; Isocyanates; Male; Neoplasms; Occupational Diseases; Occupational Exposure; Polyurethanes; Prostatic Neoplasms; Sweden; Toluene 2,4-Diisocyanate	1993
Toluene diisocyanate induced asthma: outcome according to persistence or cessation of exposure. British journal of industrial medicine, 1993, Volume: 50, Issue:1 Topics: Adult; Asthma; Chemical Industry; Follow-Up Studies; Forced Expiratory Volume; Humans; Occupational Diseases; Occupational Exposure; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate; Vital Capacity	1993
Mast cells in the airway mucosa and rapid development of occupational asthma induced by toluene diisocyanate. The American review of respiratory disease, 1993, Volume: 147, Issue:4 Topics: Adult; Aged; Asthma; Bronchi; Female; Humans; Male; Mast Cells; Middle Aged; Mucous Membrane; Occupational Diseases; Toluene 2,4-Diisocyanate	1993
[Toluene diisocyanate-induced bronchial hyperreactivity in an animal model of occupationally-induced lung diseases]. Pneumologie (Stuttgart, Germany), 1993, Volume: 47, Issue:3 Topics: Animals; Bronchial Hyperreactivity; Lung Volume Measurements; Maximum Allowable Concentration; Occupational Diseases; Rabbits; Toluene 2,4-Diisocyanate	1993
Time-period effects in longitudinal studies measuring average rates of change. Statistics in medicine, 1993, May-15, Volume: 12, Issue:9 Topics: Bias; Forced Expiratory Volume; Humans; Longitudinal Studies; Lung Diseases; Models, Statistical; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate	1993
Cancer incidence and mortality in the Swedish polyurethane foam manufacturing industry. British journal of industrial medicine, 1993, Volume: 50, Issue:6 Topics: Adult; Aged; Cause of Death; Chemical Industry; Cohort Studies; Cyanates; Female; Humans; Incidence; Isocyanates; Male; Middle Aged; Neoplasms; Occupational Diseases; Occupational Exposure; Sweden; Time Factors; Toluene 2,4-Diisocyanate	1993
Bronchial responsiveness to ultrasonic fog in occupational asthma due to toluene diisocyanate. Chest, 1993, Volume: 104, Issue:4 Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Male; Methacholine Chloride; Occupational Diseases; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Ultrasonics; Water	1993
Toluene diisocyanate induction of airway hyperresponsiveness at the threshold limit value (10 ppb) in rabbits. Lung, 1995, Volume: 173, Issue:6 Topics: Acetylcholine; Airway Resistance; Animals; Blood Pressure; Bronchial Hyperreactivity; Bronchial Provocation Tests; Disease Models, Animal; Elasticity; Lung Diseases; Maximum Allowable Concentration; Occupational Diseases; Rabbits; Reproducibility of Results; Toluene 2,4-Diisocyanate	1995
Association between toluene diisocyanate-induced asthma and DQB1 markers: a possible role for aspartic acid at position 57. The European respiratory journal, 1996, Volume: 9, Issue:2 Topics: Adult; Alleles; Aspartic Acid; Asthma; Female; Gene Frequency; Genetic Markers; Haplotypes; HLA-DQ alpha-Chains; HLA-DQ Antigens; HLA-DQ beta-Chains; Humans; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Polymerase Chain Reaction; Toluene 2,4-Diisocyanate	1996
Role of substance P and neurokinin A in toluene diisocyanate-induced increased airway responsiveness in rabbits. Lung, 1996, Volume: 174, Issue:2 Topics: Acetylcholine; Administration, Inhalation; Airway Resistance; Animals; Bronchi; Bronchoconstriction; Capsaicin; Disease Models, Animal; Lung Diseases; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Occupational Diseases; Rabbits; Receptors, Neurokinin-2; Substance P; Toluene 2,4-Diisocyanate; Trachea	1996
Seroimmunological characteristics of Korean workers exposed to toluene diisocyanate. Environmental research, 1997, Volume: 75, Issue:1 Topics: Adult; Asthma; Female; Humans; Immunoglobulin E; Immunoglobulin G; Korea; Male; Middle Aged; Occupational Diseases; Sensitivity and Specificity; Toluene 2,4-Diisocyanate	1997
Prognostic factors for toluene diisocyanate-induced occupational asthma after removal from exposure. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1997, Volume: 27, Issue:10 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Environmental Exposure; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Longitudinal Studies; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Prognosis; Smoking; Steroids; Toluene 2,4-Diisocyanate	1997
Expression of interleukin (IL)-4 and IL-5 proteins in asthma induced by toluene diisocyanate (TDI). Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1997, Volume: 27, Issue:11 Topics: Adult; Asthma; Biopsy; Bronchi; Chronic Disease; Eosinophils; Female; Humans; Immunohistochemistry; Interleukin-4; Interleukin-5; Male; Mast Cells; Middle Aged; Mucous Membrane; Occupational Diseases; T-Lymphocytes; Toluene 2,4-Diisocyanate	1997
Toluene diisocyanate exposure in a glove manufacturing plant. Journal of toxicology. Clinical toxicology, 1998, Volume: 36, Issue:1-2 Topics: Adolescent; Adult; Female; Gloves, Protective; Headache; Humans; Latex; Lung; Male; Muscular Diseases; Occupational Diseases; Occupational Exposure; Pain; Spectrophotometry, Infrared; Toluene 2,4-Diisocyanate	1998
Heterogeneity of IgE response to TDI-HSA conjugates by ELISA in toluene diisocyanate (TDI) -induced occupational asthma (OA) patients. Journal of Korean medical science, 1998, Volume: 13, Issue:2 Topics: Antibody Specificity; Asthma; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin E; Occupational Diseases; Serum Albumin; Toluene 2,4-Diisocyanate	1998
Diisocyanate antigen-enhanced production of monocyte chemoattractant protein-1, IL-8, and tumor necrosis factor-alpha by peripheral mononuclear cells of workers with occupational asthma. The Journal of allergy and clinical immunology, 1998, Volume: 102, Issue:2 Topics: Adult; Antigens; Asthma; Biomarkers, Tumor; Chemokine CCL2; Chemokines; Cyanates; Female; Humans; Interleukin-8; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha; Tumor Protein, Translationally-Controlled 1	1998
Nasal response in subjects undergoing challenges by inhaling occupational agents causing asthma through the nose and mouth. Allergy, 1998, Volume: 53, Issue:9 Topics: Administration, Inhalation; Adult; Allergens; Asthma; Female; Flour; Forced Expiratory Volume; Galactans; Humans; Male; Mannans; Middle Aged; Mouth Mucosa; Nasal Mucosa; Nasal Provocation Tests; Occupational Diseases; Occupational Exposure; Plant Gums; Toluene 2,4-Diisocyanate	1998
Increase in non-specific bronchial hyperresponsiveness without specific response to isocyanate in isocyanate-induced asthma: a pilot study. Respiratory medicine, 1998, Volume: 92, Issue:9 Topics: Adult; Air Pollutants, Occupational; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Female; Humans; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Parasympathomimetics; Pilot Projects; Predictive Value of Tests; Statistics, Nonparametric; Toluene 2,4-Diisocyanate	1998
Neutrophil activation following TDI bronchial challenges to the airway secretion from subjects with TDI-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29, Issue:10 Topics: Adult; Asthma; Bronchi; Bronchoconstrictor Agents; Female; Humans; Interleukin-8; Male; Methacholine Chloride; Middle Aged; Neutrophil Activation; Occupational Diseases; Peroxidase; Sputum; Toluene 2,4-Diisocyanate	1999
Respiratory health surveillance in a toluene di-isocyanate production unit, 1967-97: clinical observations and lung function analyses. Occupational and environmental medicine, 2000, Volume: 57, Issue:1 Topics: Asthma; Cohort Studies; Cross-Sectional Studies; Female; Forced Expiratory Volume; Humans; Incidence; Longitudinal Studies; Male; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate; Vital Capacity	2000
Association between HLA genes and susceptibility to toluene diisocyanate-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2000, Volume: 30, Issue:5 Topics: Adult; Asthma; Female; Genes, MHC Class II; Genetic Predisposition to Disease; HLA-DQ alpha-Chains; HLA-DQ Antigens; HLA-DQ beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Male; Occupational Diseases; Toluene 2,4-Diisocyanate	2000
Increase in airway hyperresponsiveness among workers exposed to methylene diphenyldiisocyanate compared to workers exposed to toluene diisocyanate at a petrochemical plant in Korea. American journal of industrial medicine, 2000, Volume: 37, Issue:6 Topics: Adult; Air Pollutants, Occupational; Allergens; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chemical Industry; Female; Forced Expiratory Volume; Humans; Intradermal Tests; Isocyanates; Korea; Male; Occupational Diseases; Petroleum; Toluene 2,4-Diisocyanate	2000
Effect of toluene diisocyanate and its corresponding amines on viability and growth of human lung fibroblasts in culture. Cell biology and toxicology, 1999, Volume: 15, Issue:5 Topics: Asthma; Carcinogens; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Cytotoxins; Fibroblasts; Humans; Hydrogen Peroxide; Lung; Occupational Diseases; Oxidants; Phenylenediamines; Tetrazolium Salts; Thiazoles; Toluene 2,4-Diisocyanate	1999
Isocyanate exposure and occupational asthma: a case-referent study. Occupational and environmental medicine, 2000, Volume: 57, Issue:12 Topics: Adolescent; Adult; Allergens; Asthma; Case-Control Studies; Female; Humans; Hypersensitivity, Immediate; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Risk Factors; Smoking; Toluene 2,4-Diisocyanate	2000
Two cases of paraoccupational asthma due to toluene diisocyanate (TDI). Occupational and environmental medicine, 2000, Volume: 57, Issue:12 Topics: Adult; Asthma; Female; Humans; Male; Middle Aged; Occupational Diseases; Paint; Polyurethanes; Toluene 2,4-Diisocyanate	2000
Health information in material safety data sheets for a chemical which causes asthma. Journal of general internal medicine, 2001, Volume: 16, Issue:2 Topics: Asthma; Drug Labeling; Humans; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate	2001
Analysis of gene expression induced by irritant and sensitizing chemicals using oligonucleotide arrays. International immunopharmacology, 2001, Volume: 1, Issue:5 Topics: Animals; Fatty Acids; Female; Gene Expression; Gene Expression Profiling; Humans; Hypersensitivity; Immunization; Irritants; Mice; Mice, Inbred BALB C; Occupational Diseases; Oligonucleotide Array Sequence Analysis; Oxazolone; Reverse Transcriptase Polymerase Chain Reaction; Toluene 2,4-Diisocyanate	2001
A longitudinal study of respiratory health of toluene diisocyanate production workers. Journal of occupational and environmental medicine, 2001, Volume: 43, Issue:10 Topics: Adult; Chemical Industry; Chi-Square Distribution; Cross-Sectional Studies; Environmental Monitoring; Epidemiological Monitoring; Female; Humans; Hydrocarbons; Longitudinal Studies; Lung Diseases; Male; Occupational Diseases; Prevalence; Regression Analysis; Respiratory Function Tests; Risk Factors; Smoking; Surveys and Questionnaires; Texas; Toluene 2,4-Diisocyanate	2001
Elevated interleukin-4 and interleukin-6 in rats sensitized with toluene diisocyanate. Industrial health, 2001, Volume: 39, Issue:4 Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Interleukin-4; Interleukin-6; Lung; Lymphocyte Subsets; Lymphocytes; Male; Occupational Diseases; Rats; Rats, Wistar; Spleen; Statistics, Nonparametric; Toluene 2,4-Diisocyanate	2001
Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates. The Journal of allergy and clinical immunology, 2002, Volume: 109, Issue:5 Topics: Adult; Asthma; Bronchial Hyperreactivity; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Time Factors; Toluene 2,4-Diisocyanate	2002
Toluene diisocyanate pulmonary disease: immunopharmacologic and mecholyl challenge studies. The Journal of allergy and clinical immunology, 1977, Volume: 59, Issue:3 Topics: Administration, Intranasal; Aerosols; Cyanates; Cyclic AMP; Histamine Release; Isoproterenol; Lymphocytes; Methacholine Compounds; Occupational Diseases; Receptors, Adrenergic, beta; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate	1977
Longitudinal study of workers employed in the manufacture of toluene-diisocyanate. The American review of respiratory disease, 1977, Volume: 116, Issue:3 Topics: Antibodies; Cyanates; Cyclic AMP; Environmental Exposure; Environmental Pollution; Histamine Release; Humans; Immunoglobulins; Longitudinal Studies; Occupational Diseases; Respiratory Function Tests; Respiratory Tract Diseases; Skin Tests; Surveys and Questionnaires; Toluene 2,4-Diisocyanate	1977
Toluene diisocyanate. Lancet (London, England), 1978, Jul-08, Volume: 2, Issue:8080 Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Cyanates; Dose-Response Relationship, Drug; Humans; Maximum Allowable Concentration; Occupational Diseases; Toluene 2,4-Diisocyanate	1978
Long-term effects on the health of men engaged in the manufacture of tolylene di-isocyanate. British journal of industrial medicine, 1975, Volume: 32, Issue:1 Topics: Age Factors; Body Height; Chemical Industry; Cyanates; Humans; Male; Occupational Diseases; Prospective Studies; Respiratory Hypersensitivity; Smoking; Spirometry; Toluene; Toluene 2,4-Diisocyanate; Vital Capacity	1975
A retrospective study of clinical, physiologic and immunologic changes in workers exposed to toluene diisocyanate. American Industrial Hygiene Association journal, 1975, Volume: 36, Issue:3 Topics: Adult; Agglutination Tests; Air Pollution; Chemical Industry; Cyanates; Environmental Exposure; Humans; Hypersensitivity, Delayed; Immunization, Passive; Middle Aged; Occupational Diseases; Pollen; Respiratory Function Tests; Respiratory Hypersensitivity; Retrospective Studies; Time Factors; Toluene 2,4-Diisocyanate	1975
Respiratory effects in toluene diisocyanate manufacture: a multidisciplinary approach. Environmental health perspectives, 1975, Volume: 11 Topics: Air Pollutants, Occupational; Antibodies; Chemical Industry; Cyanates; Dose-Response Relationship, Drug; Environmental Exposure; Eosinophils; Humans; Immunoglobulins; Leukocyte Count; Louisiana; Lymphocyte Activation; Maximum Allowable Concentration; Occupational Diseases; Occupational Medicine; Respiratory Function Tests; Respiratory Tract Diseases; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate	1975
Epidemiology of toluene diisocyanate (TDI)-induced respiratory disease. Environmental health perspectives, 1975, Volume: 11 Topics: Asthma; Bronchitis; Chemical Industry; Cyanates; Environmental Exposure; Eosinophils; Forced Expiratory Volume; Humans; Leukocyte Count; Lung Diseases, Obstructive; Maximum Allowable Concentration; Occupational Diseases; Respiratory Tract Diseases; Toluene 2,4-Diisocyanate	1975
Occupational type test for the etiological diagnosis of asthma due to toluene di-isocyanate. Respiration; international review of thoracic diseases, 1976, Volume: 33, Issue:1 Topics: Acetylcholine; Adult; Aerosols; Asthma; Bronchi; Cyanates; Evaluation Studies as Topic; Forced Expiratory Volume; Humans; Male; Methods; Occupational Diseases; Toluene 2,4-Diisocyanate	1976
Bronchial provocation tests in etiologic diagnosis and analysis of asthma. The American review of respiratory disease, 1975, Volume: 112, Issue:6 Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Aspergillus fumigatus; Asthma; Bronchi; Bronchodilator Agents; Cromolyn Sodium; Dust; Environmental Exposure; Flour; Foreign-Body Reaction; Granuloma; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immunoglobulin E; Immunoglobulin G; Occupational Diseases; Piperazines; Platinum; Pulmonary Alveoli; Resins, Plant; Resins, Synthetic; Respiratory Function Tests; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate; Wood	1975
[Asthma caused by di-isocyanate]. Ugeskrift for laeger, 1976, Mar-01, Volume: 138, Issue:10 Topics: Asthma; Cyanates; Environmental Exposure; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1976
Accidental exposure to isocyanate fumes in a group of firemen. British journal of industrial medicine, 1976, Volume: 33, Issue:2 Topics: Adult; Cyanates; Fires; Follow-Up Studies; Forced Expiratory Volume; Gastrointestinal Diseases; Humans; Male; Occupational Diseases; Respiratory Tract Diseases; Smoking; Toluene 2,4-Diisocyanate; Vital Capacity	1976
Neurological complications after a single severe exposure to toluene di-isocyanate. British journal of industrial medicine, 1976, Volume: 33, Issue:2 Topics: Adult; Cyanates; Depression; Fires; Headache; Humans; Male; Memory Disorders; Mental Recall; Middle Aged; Nervous System Diseases; Occupational Diseases; Personality Disorders; Time Factors; Toluene 2,4-Diisocyanate; Wechsler Scales	1976
[Asthma and respiratory symptome induced by isocyanates]. Duodecim; laaketieteellinen aikakauskirja, 1976, Volume: 92, Issue:11 Topics: Adult; Asthma; Bronchitis; Cyanates; Environmental Exposure; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1976
[Occupational liver pathology induced by toluylene diisocyanate]. Gigiena truda i professional'nye zabolevaniia, 1976, Issue:11 Topics: Adult; Chemical and Drug Induced Liver Injury; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1976
Occupational asthma caused by low molecular weight chemical agents. The Journal of allergy and clinical immunology, 1977, Volume: 60, Issue:2 Topics: Anhydrides; Asthma; Humans; Lymphokines; Molecular Weight; Occupational Diseases; Occupational Medicine; Phthalic Acids; Toluene 2,4-Diisocyanate; Tricarboxylic Acids	1977
Chronic pulmonary function loss from exposure to toluene diisocyanate. British journal of industrial medicine, 1977, Volume: 34, Issue:3 Topics: Adult; Cyanates; Environmental Exposure; Female; Forced Expiratory Volume; Humans; Lung; Lung Diseases; Male; Occupational Diseases; Toluene 2,4-Diisocyanate	1977
Toluene di-isocyanate (TDI). Clinical otolaryngology and allied sciences, 1977, Volume: 2, Issue:3 Topics: Asthma; Cyanates; Humans; Nasal Polyps; Occupational Diseases; Respiratory System; Toluene 2,4-Diisocyanate; United Kingdom	1977
[Occupational exposure to polyurethanes]. L'union medicale du Canada, 1977, Volume: 106, Issue:12 Topics: Humans; Lung Diseases; Occupational Diseases; Polyurethanes; Risk; Toluene 2,4-Diisocyanate	1977
Recurrent nocturnal asthma due to tolylene di-isocyanate: a case report. Clinical allergy, 1978, Volume: 8, Issue:2 Topics: Adult; Allergens; Asthma; Circadian Rhythm; Cyanates; Humans; Male; Occupational Diseases; Occupations; Recurrence; Toluene 2,4-Diisocyanate	1978
Chemical hypersusceptibility. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1978, Volume: 20, Issue:5 Topics: Adult; alpha 1-Antitrypsin Deficiency; Anemia, Sickle Cell; Antibodies; Carbon Disulfide; Dermatitis, Occupational; Environmental Exposure; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Male; Occupational Diseases; Respiratory Hypersensitivity; Smoking; Toluene 2,4-Diisocyanate	1978
Tolyl-specific IgE antibodies in workders with hypersensitivity to toluene diisocyanate. American Industrial Hygiene Association journal, 1978, Volume: 39, Issue:6 Topics: Antibodies; Antibody Specificity; Cyanates; Environmental Exposure; Haptens; Humans; Hypersensitivity; Immunoglobulin E; Occupational Diseases; Radioimmunoassay; Toluene 2,4-Diisocyanate	1978
[Bronchial asthma presumably caused by isocyanate in "Yamanaka, Japan-Ware" workers (author's transl)]. Sangyo igaku. Japanese journal of industrial health, 1978, Volume: 20, Issue:2 Topics: Adult; Asthma; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1978
[Hematological damage of occupational origin in industry]. La Medicina del lavoro, 1978, Volume: 69 Suppl 3, Issue:3 Suppl Topics: Air Pollutants; Air Pollutants, Occupational; Benzene; Benzene Derivatives; Environmental Pollutants; Hematologic Diseases; Humans; Industry; Leukemia; Leukemia, Radiation-Induced; Metals; Occupational Diseases; Toluene 2,4-Diisocyanate; Vinyl Chloride	1978
Occupational lung disease. Primary care, 1978, Volume: 5, Issue:3 Topics: Asthma; Berylliosis; Bronchitis; Byssinosis; Carcinoma, Bronchogenic; Environmental Exposure; Humans; Lung Diseases; Lung Neoplasms; Occupational Diseases; Pneumoconiosis; Pulmonary Alveoli; Respiratory Hypersensitivity; Silicosis; Toluene 2,4-Diisocyanate	1978
Patterns of airway reactivity to asthma produced by exposure to toluene di-isocyanate. Chest, 1979, Volume: 75, Issue:2 Suppl Topics: Air Pollutants; Air Pollutants, Occupational; Airway Resistance; Asthma; Bronchi; Cyanates; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Humans; Maximal Expiratory Flow-Volume Curves; Methacholine Compounds; Occupational Diseases; Ohio; Toluene 2,4-Diisocyanate	1979
Evidence of a safe level of TDI. Food and cosmetics toxicology, 1979, Volume: 17, Issue:1 Topics: Cyanates; Forced Expiratory Volume; Humans; Lung Diseases; Occupational Diseases; Respiratory Hypersensitivity; Time Factors; Toluene 2,4-Diisocyanate	1979
Inhalation challenge and pharmacologic studies of toluene diisocyanate (TDI)-sensitive workers. The Journal of allergy and clinical immunology, 1979, Volume: 64, Issue:2 Topics: Aerosols; Complement System Proteins; Cromolyn Sodium; Cyanates; Cyclic AMP; Environmental Exposure; Histamine; Humans; Hypersensitivity; Lymphocytes; Methacholine Compounds; Occupational Diseases; Toluene 2,4-Diisocyanate	1979
Peak flow rate records in the diagnosis of occupational asthma due to isocyanates. Thorax, 1979, Volume: 34, Issue:3 Topics: Asthma; Cyanates; England; Humans; Occupational Diseases; Peak Expiratory Flow Rate; Printing; Time Factors; Toluene 2,4-Diisocyanate	1979
[Diseases caused by diisocyanates. 1. Irritation of the respiratory system and skin]. Dermatosen in Beruf und Umwelt. Occupation and environment, 1978, Volume: 26, Issue:6 Topics: Cyanates; Dermatitis, Contact; Dermatitis, Occupational; Environmental Exposure; Fever; Humans; Lung Diseases; Maximum Allowable Concentration; Occupational Diseases; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate	1978
[Diseases caused by diisocyanates. 2. Diisocyanate asthma]. Dermatosen in Beruf und Umwelt. Occupation and environment, 1979, Volume: 27, Issue:1 Topics: Asthma; Cyanates; Humans; Immune Complex Diseases; Immunity, Cellular; Immunoglobulin E; Occupational Diseases; Toluene 2,4-Diisocyanate	1979
Occupational asthma: overview and mechanisms. The Journal of allergy and clinical immunology, 1979, Volume: 64, Issue:6 pt 2 Topics: Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Occupational Diseases; Toluene 2,4-Diisocyanate	1979
Inhalation challenge testing with toluene diisocyanate. The Journal of allergy and clinical immunology, 1979, Volume: 64, Issue:6 pt 2 Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Occupational Diseases; Toluene 2,4-Diisocyanate	1979
A proposed standardized method for bronchoprovocation tests in toluene diisocyanate--induced asthma. The Journal of allergy and clinical immunology, 1979, Volume: 64, Issue:6 pt 2 Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Occupational Diseases; Toluene 2,4-Diisocyanate	1979
[On the pathogenesis of isocyanate-induced asthma]. Respiration; international review of thoracic diseases, 1979, Volume: 38, Issue:5 Topics: Adult; Asthma; Cyanates; Humans; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Respiratory Function Tests; Toluene 2,4-Diisocyanate	1979
Presence of tolyl-specific IgE and absence of IgG antibodies in workers exposed to toluene diisocyanate. Journal of environmental science and health. Part C: Environmental health sciences, 1979, Volume: 13, Issue:3 Topics: Cyanates; Drug Hypersensitivity; Humans; Immunoenzyme Techniques; Immunoglobulin E; Immunoglobulin G; Occupational Diseases; Radioimmunoassay; Toluene 2,4-Diisocyanate	1979
Bathtub refinisher's lung: an unusual response to toluene diisocyanate. The American review of respiratory disease, 1978, Volume: 118, Issue:5 Topics: Alveolitis, Extrinsic Allergic; Cyanates; Humans; Intradermal Tests; Lymphocyte Activation; Male; Middle Aged; Occupational Diseases; Respiratory Function Tests; Toluene 2,4-Diisocyanate	1978
Airway mucosal inflammation in occupational asthma induced by toluene diisocyanate. The American review of respiratory disease, 1992, Volume: 145, Issue:1 Topics: Adolescent; Adult; Asthma; Basement Membrane; Bronchi; Bronchoscopy; Eosinophils; Epithelium; Female; Humans; Inflammation; Male; Mast Cells; Middle Aged; Mucous Membrane; Occupational Diseases; Toluene 2,4-Diisocyanate	1992
Effect of cessation of exposure to toluene diisocyanate (TDI) on bronchial mucosa of subjects with TDI-induced asthma. The American review of respiratory disease, 1992, Volume: 145, Issue:1 Topics: Adult; Asthma; Basement Membrane; Biopsy; Bronchi; Bronchoscopy; Female; Humans; Inflammation; Male; Middle Aged; Mucous Membrane; Occupational Diseases; Toluene 2,4-Diisocyanate	1992
Occupational asthma caused by a prepolymer but not the monomer of toluene diisocyanate (TDI). The Journal of allergy and clinical immunology, 1992, Volume: 89, Issue:6 Topics: Adult; Antibodies; Antibody Specificity; Asthma; Bronchial Provocation Tests; Chronic Disease; Construction Materials; Humans; Male; Middle Aged; Occupational Diseases; Polymers; Spirometry; Structure-Activity Relationship; Time Factors; Toluene 2,4-Diisocyanate	1992
Clinical and immunological evaluation of isocyanate-exposed workers. Journal of Korean medical science, 1992, Volume: 7, Issue:2 Topics: Adult; Asthma; Bronchial Provocation Tests; Humans; Immunoglobulin E; Occupational Diseases; Occupational Exposure; Serum Albumin; Toluene 2,4-Diisocyanate	1992
Occupational lung diseases in the industrializing and industrialized world due to modern industries and modern pollutants. Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1992, Volume: 73, Issue:1 Topics: Antimony; Arsenic; Boron; Developing Countries; Gases; Humans; Lung Diseases; Occupational Diseases; Phosphorus; Semiconductors; Toluene 2,4-Diisocyanate	1992
Abnormal lung function in polyurethane foam producers. Weak relationship to toluene diisocyanate exposures. The American review of respiratory disease, 1992, Volume: 146, Issue:4 Topics: Adult; Asthma; Bronchitis; Construction Materials; Female; Humans; Male; Occupational Diseases; Occupational Exposure; Polyurethanes; Prevalence; Regression Analysis; Respiratory Function Tests; Risk Factors; Smoking; Toluene 2,4-Diisocyanate	1992
Isocyanate-induced asthma: results of inhalation tests with TDI, MDI and methacholine. International archives of occupational and environmental health, 1991, Volume: 63, Issue:1 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Isocyanates; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate	1991
Toluene diisocyanate-induced asthma: clinical findings and bronchial responsiveness studies in 113 exposed subjects with work-related respiratory symptoms. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1991, Volume: 33, Issue:6 Topics: Adult; Asthma; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Occupational Diseases; Spirometry; Toluene 2,4-Diisocyanate; Vital Capacity	1991
Late asthmatic reactions, airway inflammation and chronic asthma in toluene-diisocyanate-sensitized subjects. Respiration; international review of thoracic diseases, 1991, Volume: 58 Suppl 1 Topics: Asthma; Bronchi; Eosinophils; Humans; Immunization; Inflammation; Lung; Occupational Diseases; Prognosis; Toluene 2,4-Diisocyanate	1991
[A case of isocyanate-induced hypersensitivity pneumonitis and a compression-air mask thought to be effective in its prevention]. Arerugi = [Allergy], 1991, Volume: 40, Issue:7 Topics: Adult; Air Pressure; Alveolitis, Extrinsic Allergic; Humans; Male; Masks; Occupational Diseases; Recurrence; Toluene 2,4-Diisocyanate	1991
Allergologic evaluation for workers exposed to toluene diisocyanate. Industrial health, 1991, Volume: 29, Issue:3 Topics: Adult; Asthma; China; Cross-Sectional Studies; Dermatitis, Contact; Female; Humans; Male; Occupational Diseases; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate	1991
[An experimental etiological study of toluene diisocyanate (TDI) induced occupational asthma]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1991, Volume: 25, Issue:6 Topics: Animals; Asthma; Disease Models, Animal; Guinea Pigs; Immunoglobulin E; Occupational Diseases; Passive Cutaneous Anaphylaxis; Toluene 2,4-Diisocyanate	1991
Increase in numbers of CD8 positive lymphocytes and eosinophils in peripheral blood of subjects with late asthmatic reactions induced by toluene diisocyanate. British journal of industrial medicine, 1991, Volume: 48, Issue:2 Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Asthma; CD8 Antigens; Eosinophils; Female; Forced Expiratory Volume; Humans; Leukocyte Count; Lung; Male; Middle Aged; Occupational Diseases; Occupational Exposure; T-Lymphocytes, Regulatory; Toluene 2,4-Diisocyanate	1991
Significant changes of bronchial responsiveness to methacholine after early asthmatic reaction to toluene diisocyanate (TDI) in a TDI-sensitive asthmatic worker. Journal of Korean medical science, 1990, Volume: 5, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Humans; Male; Methacholine Chloride; Occupational Diseases; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate	1990
Persistence of toluene diisocyanate-induced asthma despite negligible workplace exposures. Chest, 1990, Volume: 97, Issue:1 Topics: Asthma; Cyanates; Forced Expiratory Volume; Humans; Longitudinal Studies; Occupational Diseases; Spirometry; Toluene 2,4-Diisocyanate; Vital Capacity	1990
Immunologic hemorrhagic pneumonia caused by isocyanates. The American review of respiratory disease, 1990, Volume: 141, Issue:1 Topics: Acute Disease; Adult; Cyanates; Enzyme-Linked Immunosorbent Assay; Hemorrhage; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Lung; Male; Occupational Diseases; Pneumonia; Radiography; Serum Albumin; Toluene 2,4-Diisocyanate	1990
Persistent reactive airway dysfunction syndrome after exposure to toluene diisocyanate. British journal of industrial medicine, 1990, Volume: 47, Issue:4 Topics: Accidents, Traffic; Adult; Asthma; Cyanates; Follow-Up Studies; Humans; Lung; Male; Middle Aged; Occupational Diseases; Prednisolone; Social Control, Formal; Time Factors; Toluene 2,4-Diisocyanate	1990
The use of an immunoassay index for antibodies against isocyanate human protein conjugates and application to human isocyanate disease. The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:1 Topics: Antibodies; Antibody Specificity; Blood Proteins; Cyanates; Enzyme-Linked Immunosorbent Assay; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate	1990
Bronchoalveolar lavage and morphology of the airways after cessation of exposure in asthmatic subjects sensitized to toluene diisocyanate. Chest, 1990, Volume: 98, Issue:3 Topics: Adult; Asthma; Biopsy; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Count; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1990
Occupational asthma due to isocyanates in Singapore. Singapore medical journal, 1990, Volume: 31, Issue:5 Topics: Adolescent; Adult; Aged; Asthma; Cyanates; Female; Humans; Infant; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1990
Hypersensitivity pneumonitis induced by toluene diisocyanate: sequelae of continuous exposure. Annals of internal medicine, 1989, Jan-01, Volume: 110, Issue:1 Topics: Adult; Alveolitis, Extrinsic Allergic; Bronchoalveolar Lavage Fluid; Cyanates; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin A; Immunoglobulin G; Leukocyte Count; Lymphocyte Activation; Lymphocytes; Male; Occupational Diseases; Serum Albumin; Toluene 2,4-Diisocyanate	1989
Immunologic specificity of isocyanate-induced IgE antibodies in serum from 10 sensitized workers. The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:1 Topics: Antibody Specificity; Asthma; Carrier Proteins; Cyanates; Haptens; Humans; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Toluene 2,4-Diisocyanate	1989
Building-related illness and antibodies to albumin conjugates of formaldehyde, toluene diisocyanate, and trimellitic anhydride. American journal of industrial medicine, 1989, Volume: 15, Issue:2 Topics: Adult; Air Pollutants, Occupational; Female; Formaldehyde; Humans; Immunoglobulin E; Immunoglobulin G; Male; Microclimate; Middle Aged; Occupational Diseases; Phthalic Anhydrides; Serum Albumin; Syndrome; Toluene 2,4-Diisocyanate	1989
[Bronchial asthma caused by isocyanate in the internal/external environment]. Ugeskrift for laeger, 1989, May-08, Volume: 151, Issue:19 Topics: Asthma; Cyanates; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1989
An epidemiologic investigation of forced expiratory volume at 1 second and respiratory symptoms among employees of a toluene diisocyanate production plant. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1989, Volume: 31, Issue:8 Topics: Adult; Age Factors; Cross-Sectional Studies; Cyanates; Environmental Exposure; Female; Forced Expiratory Volume; Humans; Male; Occupational Diseases; Respiratory Tract Diseases; Sex Factors; Texas; Toluene 2,4-Diisocyanate	1989
Hypersensitivity pneumonitis and toluene diisocyanate. Annals of internal medicine, 1989, Oct-15, Volume: 111, Issue:8 Topics: Alveolitis, Extrinsic Allergic; Cyanates; Humans; Male; Occupational Diseases; Toluene 2,4-Diisocyanate	1989
[Occupational toluene diisocyanate (TDI) asthma--inhalation challenge test and TDI-HSA (human serum albumin) skin test and detection of specific IgE]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1989, Volume: 12, Issue:3 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Immunoglobulin E; Male; Occupational Diseases; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate	1989
Atropine does not inhibit late asthmatic responses induced by toluene-diisocyanate in sensitized subjects. The American review of respiratory disease, 1987, Volume: 136, Issue:5 Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Atropine; Carbachol; Cyanates; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1987
Occupational asthma due to toluene diisocyanate among velcro-like tape manufacturers. American journal of industrial medicine, 1988, Volume: 14, Issue:1 Topics: Adhesives; Air Pollutants, Occupational; Asthma; Cyanates; Female; Humans; Male; Occupational Diseases; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Ventilation	1988
Increases in airway responsiveness following acute exposure to respiratory irritants. Reactive airway dysfunction syndrome or occupational asthma? Chest, 1988, Volume: 94, Issue:3 Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Female; Humans; Hydrochloric Acid; Male; Middle Aged; Occupational Diseases; Respiratory Tract Diseases; Sulfuric Acids; Tetrachloroethylene; Toluene 2,4-Diisocyanate	1988
Cross-reaction between aromatic isocyanates (TDI and MDI): a specific bronchial provocation test study. Clinical allergy, 1988, Volume: 18, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Cross Reactions; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate	1988
Recurrent asthma induced by toluene diisocyanate. Thorax, 1988, Volume: 43, Issue:8 Topics: Adult; Asthma; Chemical Industry; Cyanates; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Recurrence; Toluene 2,4-Diisocyanate	1988
Increased neutrophil leukocyte chemotaxis induced by release of a serum factor in toluene-diisocyanate (TDI) asthma. Lung, 1988, Volume: 166, Issue:6 Topics: Adult; Asthma; Bronchial Provocation Tests; Chemotactic Factors; Chemotaxis, Leukocyte; Cyanates; Female; Humans; Interleukin-8; Male; Neutrophils; Occupational Diseases; Toluene 2,4-Diisocyanate	1988
A 10-year follow-up study of a group of workers exposed to isocyanates. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1985, Volume: 27, Issue:1 Topics: Adult; Cyanates; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Isocyanates; Lung Diseases, Obstructive; Male; Middle Aged; Occupational Diseases; Smoking; Time Factors; Toluene 2,4-Diisocyanate; Vital Capacity	1985
TDI-induced oculorhinitis and bronchial asthma. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1985, Volume: 27, Issue:1 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Endophthalmitis; Humans; Immunoglobulin E; Male; Middle Aged; Occupational Diseases; Paint; Rhinitis; Toluene 2,4-Diisocyanate	1985
Toluene diisocyanate and lung function. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:3 Topics: Chemical Industry; Cyanates; Humans; Lung Diseases; Occupational Diseases; Respiratory Function Tests; Smoking; Toluene 2,4-Diisocyanate	1985
Occupational asthma in a steel coating plant. British journal of industrial medicine, 1985, Volume: 42, Issue:8 Topics: Adult; Asthma; Cross-Sectional Studies; Cyanates; Disease Outbreaks; England; Female; Follow-Up Studies; Humans; Male; Metallurgy; Middle Aged; Occupational Diseases; Peak Expiratory Flow Rate; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate	1985
[Functional diagnosis of myocardial diseases in patients exposed to various chemical substances]. Vrachebnoe delo, 1985, Issue:12 Topics: Adolescent; Adult; Cyanates; Female; Heart Function Tests; Humans; Insecticides; Male; Middle Aged; Myocarditis; Occupational Diseases; Toluene 2,4-Diisocyanate	1985
Toluene diisocyanate-induced asthma without airway hyperresponsiveness. European journal of respiratory diseases, 1986, Volume: 68, Issue:2 Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate	1986
Persistent airways disease caused by toluene diisocyanate. The American review of respiratory disease, 1986, Volume: 134, Issue:1 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate	1986
Chronic asthma due to toluene diisocyanate. Chest, 1986, Volume: 90, Issue:4 Topics: Adult; Asthma; Chronic Disease; Cyanates; Forced Expiratory Volume; Humans; Middle Aged; Occupational Diseases; Prognosis; Retrospective Studies; Time Factors; Toluene 2,4-Diisocyanate; Vital Capacity	1986
[Health hazards in workers of small scale polyurethane production factory]. Sangyo igaku. Japanese journal of industrial health, 1986, Volume: 28, Issue:2 Topics: Adolescent; Adult; Aged; Asthma; Chemical Industry; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Morbidity; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate	1986
Determination in urine of diisocyanate-derived amines from occupational exposure by gas chromatography-mass fragmentography. The Analyst, 1986, Volume: 111, Issue:9 Topics: Amines; Cyanates; Gas Chromatography-Mass Spectrometry; Humans; Occupational Diseases; Toluene 2,4-Diisocyanate	1986
Determination of occupational exposure to toluene diisocyanate by biological monitoring. Journal of chromatography, 1986, Oct-03, Volume: 367, Issue:2 Topics: Amines; Cyanates; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Monitoring, Physiologic; Occupational Diseases; Phenylenediamines; Toluene 2,4-Diisocyanate	1986
Late, but not early, asthmatic reactions induced by toluene-diisocyanate are associated with increased airway responsiveness to methacholine. European journal of respiratory diseases, 1986, Volume: 69, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate	1986
Bathtub refinishers' lung. Journal of occupational medicine. : official publication of the Industrial Medical Association, 1987, Volume: 29, Issue:5 Topics: Cyanates; Humans; Occupational Diseases; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate	1987
[Body reactivity of workers in contact with the chemical allergen toluene diisocyanate]. Gigiena truda i professional'nye zabolevaniia, 1987, Issue:5 Topics: Adult; Allergens; Cyanates; Female; Humans; Immunization; Male; Occupational Diseases; Skin Tests; Toluene 2,4-Diisocyanate	1987
Toluene diisocyanate respiratory reactions. I. Reassessment of the problem. International archives of allergy and applied immunology, 1987, Volume: 84, Issue:1 Topics: Adult; Asthma; Cyanates; Humans; Immunoglobulins; Isomerism; Middle Aged; Occupational Diseases; Respiration; Toluene 2,4-Diisocyanate	1987